iopodic acid 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
iodine-containing contrast media 1474 5587-89-3

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • ipodate
  • oragrafin sodium
  • iopodic acid
  • bilimin acid
  • bilopten
  • oragrafin
  • calcium iopodate
  • ipodate sodium
  • sodium iopodate
  • ipodate calcium
Ionic monomeric contrast media. Usually the sodium or calcium salts are used for examination of the gall bladder and biliary tract. (From Martindale, The Extra Pharmacopoeia, 30th ed, p704)
  • Molecular weight: 597.96
  • Formula: C12H13I3N2O2
  • CLOGP: 4.38
  • LIPINSKI: 1
  • HAC: 4
  • HDO: 1
  • TPSA: 52.90
  • ALOGS: -4.86
  • ROTB: 4

  • Status: OFM

  • Legend:
    OFP - off patent
    OFM - off market
    ONP - on patent

Drug dosage:

None

ADMET properties:

None

Approvals:

DateAgencyCompanyOrphan
March 15, 1962 FDA BRACCO

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

None

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

SourceCodeDescription
ATC V08AC08 VARIOUS
CONTRAST MEDIA
X-RAY CONTRAST MEDIA, IODINATED
Watersoluble, hepatotropic X-ray contrast media
ATC V08AC10 VARIOUS
CONTRAST MEDIA
X-RAY CONTRAST MEDIA, IODINATED
Watersoluble, hepatotropic X-ray contrast media
MeSH PA D003287 Contrast Media
MeSH PA D064907 Diagnostic Uses of Chemicals

Drug Use | Suggest Off label Use Form| |View source of the data|

DiseaseRelationSNOMED_IDDOID
Diagnostic aid indication 2949005
Acute nephropathy contraindication 58574008
Hepatic failure contraindication 59927004
Kidney disease contraindication 90708001 DOID:557
Hb SS disease contraindication 127040003 DOID:10923
Asthma contraindication 195967001 DOID:2841
Pregnancy, function contraindication 289908002
Pheochromocytoma contraindication 302835009
Hypertensive Emergencies contraindication




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

Dissociation levelDissociation constantType (acidic/basic)
pKa1 4.12 acidic
pKa2 7.83 Basic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

IDSource
4017623 VUID
N0000178897 NUI
D01015 KEGG_DRUG
1221-56-3 SECONDARY_CAS_RN
4017623 VANDF
4017624 VANDF
4019790 VANDF
C4082438 UMLSCUI
CHEBI:81496 CHEBI
CHEMBL1201243 ChEMBL_ID
CHEMBL1201033 ChEMBL_ID
CHEMBL2068725 ChEMBL_ID
DB09333 DRUGBANK_ID
1151-11-7 SECONDARY_CAS_RN
5241 PUBCHEM_CID
1911 RXNORM
2949 MMSL
4914 MMSL
4915 MMSL
d01439 MMSL
001226 NDDF
001227 NDDF
001228 NDDF
395877001 SNOMEDCT_US
773169004 SNOMEDCT_US
87445005 SNOMEDCT_US
D007487 MESH_DESCRIPTOR_UI
1033 INN_ID
F316LLW9WW UNII

Pharmaceutical products:

None