alpiropride 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
sulpiride derivatives and analogues 135 81982-32-3

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • alpiropride
  • Molecular weight: 382.48
  • Formula: C17H26N4O4S
  • CLOGP: 1.72
  • LIPINSKI: 0
  • HAC: 8
  • HDO: 3
  • TPSA: 113.76
  • ALOGS: -3.23
  • ROTB: 7

Drug dosage:

None

ADMET properties:

PropertyValueReference
Vd (Volume of distribution) 2.30 L/kg Lombardo F, Berellini G, Obach RS
CL (Clearance) 5.47 mL/min/kg Lombardo F, Berellini G, Obach RS
t_half (Half-life) 4.80 hours Lombardo F, Berellini G, Obach RS

Approvals:

None

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

None

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

None

Drug Use | Suggest Off label Use Form| |View source of the data|

None




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

Dissociation levelDissociation constantType (acidic/basic)
pKa1 9.87 acidic
pKa2 8.45 Basic
pKa3 0.66 Basic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

IDSource
C2346723 UMLSCUI
CHEMBL2104024 ChEMBL_ID
71253 PUBCHEM_CID
5290 INN_ID
1768UW0XS1 UNII

Pharmaceutical products:

None