fentonium 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
quaternary ammonium compounds 1167 5868-06-4

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • fentonium
  • fentonium bromide
  • phenthonium
  • phenthonium bromide
  • phentonium
  • phentonium bromide
less effect on eye, heart & gland functions than atropine; proposed for therapy of gastrointestinal ulcers; minor descriptor (78-84); on-line & Index Medicus search ATROPINE DERIVATIVES (78-84); RN given refers to bromide(3(S)-endo)-isomer
  • Molecular weight: 484.62
  • Formula: C31H34NO4
  • CLOGP: 1.52
  • LIPINSKI: 0
  • HAC: 5
  • HDO: 1
  • TPSA: 63.60
  • ALOGS: -6.95
  • ROTB: 9

Drug dosage:

DoseUnitRoute
60 mg O

ADMET properties:

None

Approvals:

None

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

None

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

SourceCodeDescription
ATC A03BB04 ALIMENTARY TRACT AND METABOLISM
DRUGS FOR FUNCTIONAL GASTROINTESTINAL DISORDERS
BELLADONNA AND DERIVATIVES, PLAIN
Belladonna alkaloids, semisynthetic, quaternary ammonium compounds

Drug Use | Suggest Off label Use Form| |View source of the data|

None




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

Dissociation levelDissociation constantType (acidic/basic)
pKa1 13.24 acidic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

IDSource
D07951 KEGG_DRUG
C0060206 UMLSCUI
CHEBI:135781 CHEBI
CHEMBL3989849 ChEMBL_ID
CHEMBL3989580 ChEMBL_ID
DB08978 DRUGBANK_ID
C100112 MESH_SUPPLEMENTAL_RECORD_UI
26BF4S8FO5 UNII
10347880 PUBCHEM_CID
3384 INN_ID
34786-74-8 SECONDARY_CAS_RN

Pharmaceutical products:

None