etofibrate 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |
| Stem definition | Drug id | CAS RN |
|---|---|---|
| clofibrate derivatives, peroxisome proliferator activated receptor-alpha(PPAR-alpha) agonists | 1106 | 31637-97-5 |
Description:
| Molecule | Description |
|---|---|
|
Synonyms:
|
analog of clofibrate with nicotinic acid substituted on the 2-carbon of the ethyl ester group; structure; RN given refers to parent cpd
|
Drug dosage:
None
ADMET properties:
| Property | Value | Reference |
|---|---|---|
| S (Water solubility) | 0.01 mg/mL | Bocci G, Oprea TI, Benet LZ |
| BDDCS (Biopharmaceutical Drug Disposition Classification System) | 2 | Bocci G, Oprea TI, Benet LZ |
Approvals:
None
FDA Adverse Event Reporting System (Female)
None
FDA Adverse Event Reporting System (Male)
None
FDA Adverse Event Reporting System (Geriatric)
None
FDA Adverse Event Reporting System (Pediatric)
None
Pharmacologic Action:
| Source | Code | Description |
|---|---|---|
| ATC | C10AB09 | CARDIOVASCULAR SYSTEM LIPID MODIFYING AGENTS LIPID MODIFYING AGENTS, PLAIN Fibrates |
| MeSH PA | D000924 | Anticholesteremic Agents |
| MeSH PA | D000963 | Antimetabolites |
| MeSH PA | D000960 | Hypolipidemic Agents |
| MeSH PA | D057847 | Lipid Regulating Agents |
| CHEBI has role | CHEBI:25212 | metabolites |
| CHEBI has role | CHEBI:35620 | vasodilator agents |
| CHEBI has role | CHEBI:35679 | antilipemic drugs |
| CHEBI has role | CHEBI:50247 | antidotes |
| CHEBI has role | CHEBI:75771 | Mus musculus metabolites |
| CHEBI has role | CHEBI:76924 | plant metabolites |
| CHEBI has role | CHEBI:76971 | Escherichia coli metabolites |
| CHEBI has role | CHEBI:84087 | human urinary metabolites |
| CHEBI has role | CHEBI:84264 | nicotinamide deaminase inhibitors |
| CHEBI has role | CHEBI:24527 | herbicides |
| CHEBI has role | CHEBI:35610 | antineoplastic agents |
| CHEBI has role | CHEBI:35821 | anticholesteremic drugs |
| CHEBI has role | CHEBI:70782 | PPAR-alpha agonist |
| CHEBI has role | CHEBI:83399 | marine xenobiotic metabolites |
Drug Use | Suggest Off label Use Form| |View source of the data|
None
🐶 Veterinary Drug Use
None
🐶 Veterinary products
None
Acid dissociation constants calculated using MoKa v3.0.0
| Dissociation level | Dissociation constant | Type (acidic/basic) |
|---|---|---|
| pKa1 | 3.03 | Basic |
Orange Book patent data (new drug applications)
None
Orange Book exclusivity data (new drug applications)
None
Bioactivity Summary:
None
External reference:
| ID | Source |
|---|---|
| D07187 | KEGG_DRUG |
| 4017661 | VANDF |
| 4019440 | VANDF |
| C0059869 | UMLSCUI |
| CHEBI:135535 | CHEBI |
| CHEBI:34648 | CHEBI |
| CHEBI:15940 | CHEBI |
| NIO | PDB_CHEM_ID |
| CHEMBL358150 | ChEMBL_ID |
| DB08983 | DRUGBANK_ID |
| C009746 | MESH_SUPPLEMENTAL_RECORD_UI |
| 65777 | PUBCHEM_CID |
| 3616 | INN_ID |
| 23TF67G79M | UNII |
| DB00627 | DRUGBANK_ID |
| 24609 | RXNORM |
| 2275 | MMSL |
| 5169 | MMSL |
| 7161 | MMSL |
| d00314 | MMSL |
| 001052 | NDDF |
| 006004 | NDDF |
| 273943001 | SNOMEDCT_US |
| 63639004 | SNOMEDCT_US |
| 703414000 | SNOMEDCT_US |
| 703900008 | SNOMEDCT_US |
| C0009003 | UMLSCUI |
| C0027996 | UMLSCUI |
| 2439 | INN_ID |
| 2797 | PUBCHEM_CID |
| 938 | PUBCHEM_CID |
| D002995 | MESH_DESCRIPTOR_UI |
Pharmaceutical products:
None