ethylestrenol 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |
| Stem definition | Drug id | CAS RN |
|---|---|---|
| anabolic steroids | 1094 | 965-90-2 |
Description:
| Molecule | Description |
|---|---|
|
Synonyms:
|
An anabolic steroid with some progestational activity and little androgenic effect.
Legend: OFP - off patent OFM - off market ONP - on patent |
Drug dosage:
| Dose | Unit | Route |
|---|---|---|
| 2 | mg | O |
ADMET properties:
None
Approvals:
| Date | Agency | Company | Orphan |
|---|---|---|---|
| May 28, 1964 | FDA |
FDA Adverse Event Reporting System (Female)
None
FDA Adverse Event Reporting System (Male)
None
FDA Adverse Event Reporting System (Geriatric)
None
FDA Adverse Event Reporting System (Pediatric)
None
Pharmacologic Action:
| Source | Code | Description |
|---|---|---|
| ATC | A14AB02 | ALIMENTARY TRACT AND METABOLISM ANABOLIC AGENTS FOR SYSTEMIC USE ANABOLIC STEROIDS Estren derivatives |
| MeSH PA | D045930 | Anabolic Agents |
| MeSH PA | D006728 | Hormones |
Drug Use | Suggest Off label Use Form| |View source of the data|
None
🐶 Veterinary Drug Use
None
🐶 Veterinary products
None
Acid dissociation constants calculated using MoKa v3.0.0
None
Orange Book patent data (new drug applications)
None
Orange Book exclusivity data (new drug applications)
None
Bioactivity Summary:
| Target | Class | Pharos | UniProt | Action | Type | Activity value (-log[M]) | Mechanism action | Bioact source | MoA source |
|---|---|---|---|---|---|---|---|---|---|
| Androgen receptor | Nuclear hormone receptor | AGONIST | CHEMBL | CHEMBL | |||||
| Sodium-dependent noradrenaline transporter | Transporter | Ki | 5.68 | DRUG MATRIX | |||||
| Muscarinic acetylcholine receptor M2 | GPCR | Ki | 6.98 | DRUG MATRIX | |||||
| Estrogen receptor | Nuclear hormone receptor | Ki | 6.50 | DRUG MATRIX | |||||
| Acetylcholinesterase | Enzyme | IC50 | 5.19 | DRUG MATRIX | |||||
| Cytochrome P450 2C19 | Enzyme | IC50 | 5.89 | DRUG MATRIX | |||||
| Sodium-dependent serotonin transporter | Transporter | Ki | 7.37 | DRUG MATRIX | |||||
| Androgen receptor | Transcription factor | Ki | 7.75 | DRUG MATRIX | |||||
| Progesterone receptor | Transcription factor | Ki | 7.59 | DRUG MATRIX |
External reference:
| ID | Source |
|---|---|
| 4018517 | VUID |
| N0000146839 | NUI |
| D01414 | KEGG_DRUG |
| 4018517 | VANDF |
| C0015099 | UMLSCUI |
| CHEBI:31578 | CHEBI |
| CHEMBL1200623 | ChEMBL_ID |
| DB01493 | DRUGBANK_ID |
| D005032 | MESH_DESCRIPTOR_UI |
| 13765 | PUBCHEM_CID |
| 6948 | IUPHAR_LIGAND_ID |
| 1107 | INN_ID |
| ADC79EK5Q8 | UNII |
| 4162 | RXNORM |
| 001251 | NDDF |
| 126170002 | SNOMEDCT_US |
| 80618000 | SNOMEDCT_US |
Pharmaceutical products:
None