epomediol 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | PK/Tox | Related Drugs | BioActivity |

Stem definitionDrug idCAS RN
1033 56084-15-2

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • epomediol
  • 2,6-Dihydroxycineol
  • clesidren
marked choleretic activity in Wistar rats; mechanism of action may be related to increases in both the bile salt dependent & independent fractions of bile
  • Molecular weight: 186.25
  • Formula: C10H18O3
  • CLOGP: 0.87
  • LIPINSKI: 0
  • HAC: 3
  • HDO: 2
  • TPSA: 49.69
  • ALOGS: -0.37
  • ROTB: 0

Drug dosage:

None

ADMET properties:

None

Predicted pharmacokinetic/toxicological properties (PK-AZ):

PropertyDescriptionValueUnitConfidenceSimilarity
kinase-safety-class ACVR2B,AXL,BRAF,CAMK2D,CDK5,CDK9,EIF2AK3,ERBB2,GRK2,ITK,MAP2K6,MAP3K21,MAPK7,NTRK2,PDK1,PDK2,PDK4,PRKDC,TEK 19
kinase-selectivity-class CHUK,PDK1 2
pfas-class PFAS structural alert (1 = True, 0 = False) 0

Approvals:

None

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

None

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

SourceCodeDescription
ATC A05BA05 ALIMENTARY TRACT AND METABOLISM
BILE AND LIVER THERAPY
LIVER THERAPY, LIPOTROPICS
Liver therapy
MeSH PA D002756 Cholagogues and Choleretics
MeSH PA D005765 Gastrointestinal Agents

Related Drugs by ATC class:

A05BA Liver therapy 7 drugs
arginine glutamatecitioloneglycyrrhizic acidornithine oxoglurateresmetiromsilymarintidiacic arginine

Drug Use | Suggest Off label Use Form| |View source of the data|

None




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

None

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

IDSource
C0059459 UMLSCUI
CHEBI:81225 CHEBI
CHEMBL3707255 ChEMBL_ID
DB13802 DRUGBANK_ID
115056 PUBCHEM_CID
C031365 MESH_SUPPLEMENTAL_RECORD_UI
KFU4XSK3BK UNII
24263 RXNORM
007163 NDDF
1310101-21-3 SECONDARY_CAS_RN

Pharmaceutical products:

None