enocitabine 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
nucleosides antiviral or antineoplastic agents, cytarabine or azacitidine derivatives 1012 55726-47-1

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • enocitabine
  • behenoylcytosine arabinoside
  • sunrabin
  • Molecular weight: 565.80
  • Formula: C31H55N3O6
  • CLOGP: 8.54
  • LIPINSKI: 2
  • HAC: 9
  • HDO: 4
  • TPSA: 131.69
  • ALOGS: -5.67
  • ROTB: 23

  • Status: OFP

  • Legend:
    OFP - off patent
    OFM - off market
    ONP - on patent

Drug dosage:

None

ADMET properties:

None

Approvals:

None

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

None

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

SourceCodeDescription
FDA MoA N0000000233 Nucleic Acid Synthesis Inhibitors
MeSH PA D000890 Anti-Infective Agents
MeSH PA D000970 Antineoplastic Agents
MeSH PA D000998 Antiviral Agents
MeSH PA D000963 Antimetabolites
MeSH PA D000964 Antimetabolites, Antineoplastic
MeSH PA D007155 Immunologic Factors
MeSH PA D007166 Immunosuppressive Agents
MeSH PA D009676 Noxae
FDA EPC N0000175595 Nucleoside Metabolic Inhibitor
CHEBI has role CHEBI:22587 antiviral agents
CHEBI has role CHEBI:35221 antimetabolite
CHEBI has role CHEBI:35610 antineoplastic agents
CHEBI has role CHEBI:35705 immunosuppressive agents

Drug Use | Suggest Off label Use Form| |View source of the data|

None




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

Dissociation levelDissociation constantType (acidic/basic)
pKa1 11.91 acidic
pKa2 12.42 acidic
pKa3 12.58 acidic
pKa4 13.11 acidic
pKa5 1.62 Basic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

IDSource
D01633 KEGG_DRUG
4018080 VANDF
C0059364 UMLSCUI
CHEBI:31537 CHEBI
CHEBI:28680 CHEBI
AR3 PDB_CHEM_ID
CHEMBL2106589 ChEMBL_ID
C015019 MESH_SUPPLEMENTAL_RECORD_UI
5121 INN_ID
9YVR68W306 UNII
71734 PUBCHEM_CID
3041 RXNORM
372 MMSL
4526 MMSL
d00201 MMSL
002649 NDDF
010917 NDDF
387511003 SNOMEDCT_US
89265009 SNOMEDCT_US
C0010711 UMLSCUI
DB00987 DRUGBANK_ID
1709 INN_ID
D003561 MESH_DESCRIPTOR_UI
6253 PUBCHEM_CID

Pharmaceutical products:

None