ribostamycin indications/contra

Stem definitionDrug idCAS RN
antibiotics, produced by Streptomyces strains 3526 25546-65-0

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • ribostamycin sulfate
  • ribostamycin
  • hetangmycin
  • vistamycin
  • ribostamycin sulfate salt
A broad-spectrum antimicrobial isolated from Streptomyces ribosifidicus.
  • Molecular weight: 454.48
  • Formula: C17H34N4O10
  • CLOGP: -5.02
  • LIPINSKI: 2
  • HAC: 14
  • HDO: 10
  • TPSA: 262.38
  • ALOGS: -0.71
  • ROTB: 6

Drug dosage:

DoseUnitRoute
1 g P

Approvals:

None

FDA Adverse Event Reporting System

None

Pharmacologic Action:

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SourceCodeDescription
ATC J01GB10 ANTIINFECTIVES FOR SYSTEMIC USE
ANTIBACTERIALS FOR SYSTEMIC USE
AMINOGLYCOSIDE ANTIBACTERIALS
Other aminoglycosides
MeSH PA D000900 Anti-Bacterial Agents
MeSH PA D000890 Anti-Infective Agents
CHEBI has role CHEBI:36047 antibacterial drug

Drug Use (View source of the data)

None

Acid dissociation constants calculated using MoKa v3.0.0

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Dissociation levelDissociation constantType (acidic/basic)
pKa1 12.57 acidic
pKa2 13.56 acidic
pKa3 13.9 acidic
pKa4 8.21 Basic
pKa5 7.69 Basic
pKa6 6.31 Basic
pKa7 5.7 Basic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

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IDSource
D02209 KEGG_DRUG
2Q5JOU7T53 UNII
3197 INN_ID
N0000168458 NDFRT
010978 NDDF
CHEMBL221572 ChEMBL_ID
33042 PUBCHEM_CID
DB03615 DRUGBANK_ID
D012271 MESH_DESCRIPTOR_UI
53797-35-6 SECONDARY_CAS_RN
CHEBI:45257 CHEBI
RIO PDB_CHEM_ID

Pharmaceutical products:

None