ribostamycin 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |
| Stem definition | Drug id | CAS RN |
|---|---|---|
| antibiotics, produced by Streptomyces strains | 3526 | 25546-65-0 |
Description:
| Molecule | Description |
|---|---|
|
Synonyms:
|
A broad-spectrum antimicrobial isolated from Streptomyces ribosifidicus.
|
Drug dosage:
| Dose | Unit | Route |
|---|---|---|
| 1 | g | P |
ADMET properties:
| Property | Value | Reference |
|---|---|---|
| Vd (Volume of distribution) | 0.25 L/kg | Lombardo F, Berellini G, Obach RS |
| CL (Clearance) | 1.50 mL/min/kg | Lombardo F, Berellini G, Obach RS |
| t_half (Half-life) | 2.50 hours | Lombardo F, Berellini G, Obach RS |
Approvals:
None
FDA Adverse Event Reporting System (Female)
None
FDA Adverse Event Reporting System (Male)
None
FDA Adverse Event Reporting System (Geriatric)
None
FDA Adverse Event Reporting System (Pediatric)
None
Pharmacologic Action:
| Source | Code | Description |
|---|---|---|
| ATC | J01GB10 | ANTIINFECTIVES FOR SYSTEMIC USE ANTIBACTERIALS FOR SYSTEMIC USE AMINOGLYCOSIDE ANTIBACTERIALS Other aminoglycosides |
| MeSH PA | D000900 | Anti-Bacterial Agents |
| MeSH PA | D000890 | Anti-Infective Agents |
| CHEBI has role | CHEBI:33281 | antibiotics |
| CHEBI has role | CHEBI:33282 | bactericides |
| CHEBI has role | CHEBI:36047 | antibacterial drugs |
| CHEBI has role | CHEBI:25212 | metabolites |
Drug Use | Suggest Off label Use Form| |View source of the data|
None
🐶 Veterinary Drug Use
None
🐶 Veterinary products
None
Acid dissociation constants calculated using MoKa v3.0.0
| Dissociation level | Dissociation constant | Type (acidic/basic) |
|---|---|---|
| pKa1 | 12.57 | acidic |
| pKa2 | 13.56 | acidic |
| pKa3 | 13.9 | acidic |
| pKa4 | 8.21 | Basic |
| pKa5 | 7.69 | Basic |
| pKa6 | 6.31 | Basic |
| pKa7 | 5.7 | Basic |
Orange Book patent data (new drug applications)
None
Orange Book exclusivity data (new drug applications)
None
Bioactivity Summary:
None
External reference:
| ID | Source |
|---|---|
| D02209 | KEGG_DRUG |
| 53797-35-6 | SECONDARY_CAS_RN |
| C0035554 | UMLSCUI |
| CHEBI:65028 | CHEBI |
| RIO | PDB_CHEM_ID |
| CHEMBL221572 | ChEMBL_ID |
| D012271 | MESH_DESCRIPTOR_UI |
| DB03615 | DRUGBANK_ID |
| 12161 | IUPHAR_LIGAND_ID |
| 3197 | INN_ID |
| 2Q5JOU7T53 | UNII |
| 33042 | PUBCHEM_CID |
| 010978 | NDDF |
| 010979 | NDDF |
Pharmaceutical products:
None