Stem definition | Drug id | CAS RN |
---|---|---|
antibiotics, produced by Streptomyces strains | 1520 | 4696-76-8 |
Dose | Unit | Route |
---|---|---|
0.60 | g | P |
None
None
None
None
None
None
Source | Code | Description |
---|---|---|
ATC | J01GB13 | ANTIINFECTIVES FOR SYSTEMIC USE ANTIBACTERIALS FOR SYSTEMIC USE AMINOGLYCOSIDE ANTIBACTERIALS Other aminoglycosides |
MeSH PA | D000900 | Anti-Bacterial Agents |
MeSH PA | D000890 | Anti-Infective Agents |
None
None
None
Dissociation level | Dissociation constant | Type (acidic/basic) |
---|---|---|
pKa1 | 13.0 | acidic |
pKa2 | 13.56 | acidic |
pKa3 | 13.99 | acidic |
pKa4 | 8.03 | Basic |
pKa5 | 7.6 | Basic |
pKa6 | 7.07 | Basic |
pKa7 | 6.11 | Basic |
pKa8 | 5.41 | Basic |
None
None
Target | Class | Pharos | UniProt | Action | Type | Activity value (-log[M]) | Mechanism action | Bioact source | MoA source |
---|---|---|---|---|---|---|---|---|---|
3-oxoacyl-[acyl-carrier-protein] synthase 3 | Enzyme | IC50 | 5.20 | CHEMBL | |||||
3-oxoacyl-[acyl-carrier-protein] synthase 3 | Unclassified | IC50 | 5.25 | CHEMBL |
ID | Source |
---|---|
D07497 | KEGG_DRUG |
C0053076 | UMLSCUI |
CHEBI:28098 | CHEBI |
9CS | PDB_CHEM_ID |
CHEMBL176 | ChEMBL_ID |
DB13673 | DRUGBANK_ID |
C001495 | MESH_SUPPLEMENTAL_RECORD_UI |
12182 | IUPHAR_LIGAND_ID |
2838 | INN_ID |
15JT14C3GI | UNII |
439318 | PUBCHEM_CID |
None