elliptinium 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |
| Stem definition | Drug id | CAS RN |
|---|---|---|
| quaternary ammonium compounds | 996 | 58337-35-2 |
Description:
| Molecule | Description |
|---|---|
|
Synonyms:
|
synthetic ellipticine deriv; RN given refers to parent cpd; structure given in first source
|
Drug dosage:
None
ADMET properties:
None
Approvals:
None
FDA Adverse Event Reporting System (Female)
None
FDA Adverse Event Reporting System (Male)
None
FDA Adverse Event Reporting System (Geriatric)
None
FDA Adverse Event Reporting System (Pediatric)
None
Pharmacologic Action:
| Source | Code | Description |
|---|---|---|
| MeSH PA | D000970 | Antineoplastic Agents |
| MeSH PA | D007202 | Indicators and Reagents |
| MeSH PA | D007364 | Intercalating Agents |
Drug Use | Suggest Off label Use Form| |View source of the data|
None
🐶 Veterinary Drug Use
None
🐶 Veterinary products
None
Acid dissociation constants calculated using MoKa v3.0.0
| Dissociation level | Dissociation constant | Type (acidic/basic) |
|---|---|---|
| pKa1 | 9.38 | acidic |
| pKa2 | 12.59 | acidic |
Orange Book patent data (new drug applications)
None
Orange Book exclusivity data (new drug applications)
None
Bioactivity Summary:
| Target | Class | Pharos | UniProt | Action | Type | Activity value (-log[M]) | Mechanism action | Bioact source | MoA source |
|---|---|---|---|---|---|---|---|---|---|
| Mast/stem cell growth factor receptor Kit | Kinase | IC50 | 6.40 | CHEMBL | |||||
| Platelet-derived growth factor receptor alpha | Kinase | IC50 | 6.15 | CHEMBL | |||||
| Fibroblast growth factor receptor 3 | Kinase | IC50 | 6.30 | CHEMBL |
External reference:
| ID | Source |
|---|---|
| C0115685 | UMLSCUI |
| CHEBI:135147 | CHEBI |
| CHEMBL16699 | ChEMBL_ID |
| CHEMBL24078 | ChEMBL_ID |
| C027767 | MESH_SUPPLEMENTAL_RECORD_UI |
| 42723 | PUBCHEM_CID |
| 1F1959S062 | UNII |
| 006100 | NDDF |
| 006101 | NDDF |
| 4783 | INN_ID |
| 58337-34-1 | SECONDARY_CAS_RN |
Pharmaceutical products:
None