dipipanone 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | PK/Tox | Related Drugs | BioActivity |

Stem definitionDrug idCAS RN
921 467-83-4

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • dipipanone
  • dipipanon
  • piperidylamidone
piperidyl analog of methadone where piperidino group replaces dimethylamino group; RN given refers to parent cpd without isomeric designation; structure
  • Molecular weight: 349.52
  • Formula: C24H31NO
  • CLOGP: 5.30
  • LIPINSKI: 1
  • HAC: 2
  • HDO: 0
  • TPSA: 20.31
  • ALOGS: -5.66
  • ROTB: 7

Drug dosage:

None

ADMET properties:

None

Predicted pharmacokinetic/toxicological properties (PK-AZ):

PropertyDescriptionValueUnitConfidenceSimilarity
kinase-safety-class ACVR2B,AKT1,AKT2,AXL,BRAF,BTK,CAMK2B,CAMK2D,CDK4,CDK5,CDK9,EIF2AK3,EPHB4,ERBB2,GRK2,ITK,JAK2,MAP3K7,MAPK10,MAPK12,MAPK7,MAPKAPK2,MET,NTRK2,PDK2,PDK4,PDPK1,PIM2,PRKDC,TEK,TGFBR1 31
kinase-selectivity-class AXL,GRK2,PDK4,SIK2 4
pfas-class PFAS structural alert (1 = True, 0 = False) 0

Approvals:

None

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

None

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

None

Drug Use | Suggest Off label Use Form| |View source of the data|

None




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

Dissociation levelDissociation constantType (acidic/basic)
pKa1 8.73 Basic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

IDSource
23405 RXNORM
C0058410 UMLSCUI
CHEBI:135479 CHEBI
CHEMBL2111157 ChEMBL_ID
DB01491 DRUGBANK_ID
C007527 MESH_SUPPLEMENTAL_RECORD_UI
13331 PUBCHEM_CID
9081 IUPHAR_LIGAND_ID
465 INN_ID
X188638Y2V UNII
003696 NDDF
387226000 SNOMEDCT_US
40974005 SNOMEDCT_US

Pharmaceutical products:

None