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2022 Update-Veterinary Drugs & Uses
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DrugCentral 2023 ๐
2022 Update-Veterinary Drugs & Uses
Search
Structure ๐
Similarity ๐
Smart API
Redial
About
Download
L1000
FAQ
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FDA-approved
EMA-approved
PMDA-approved
Target Card Uniprot Example:
P23975
denaverine ๐ถ
Veterinary Use |
Indications/Contra
| FAERs-F
| FAERs-M
| Orange Bk
| BioActivity |
Stem definition
Drug id
CAS RN
spasmolytics with a papaverine-like action
805
3579-62-2
Description:
Molecule
Description
Molfile
Inchi
Smiles
Synonyms:
spasmalgan
denaverine hydrochloride
denaverine
Molecular weight: 383.53
Formula: C24H33NO3
CLOGP: 5.66
LIPINSKI: 1
HAC: 4
HDO: 0
TPSA: 38.77
ALOGS: -5.58
ROTB: 12
Drug dosage:
None
ADMET properties:
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entries
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Property
Value
Reference
Vd (Volume of distribution)
7.10 L/kg
Lombardo F, Berellini G, Obach RS
MRTD (Maximum Recommended Therapeutic Daily Dose)
6.70 ยตM/kg/day
Contrera JF, Matthews EJ, Kruhlak NL, Benz RD
CL (Clearance)
5.70 mL/min/kg
Lombardo F, Berellini G, Obach RS
t_half (Half-life)
34 hours
Lombardo F, Berellini G, Obach RS
Showing 1 to 4 of 4 entries
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Approvals:
None
FDA Adverse Event Reporting System (Female)
None
FDA Adverse Event Reporting System (Male)
None
FDA Adverse Event Reporting System (Geriatric)
None
FDA Adverse Event Reporting System (Pediatric)
None
Pharmacologic Action:
None
Drug Use
| Suggest Off label Use Form|
|View source of the data|
None
๐ถ Veterinary Drug Use
None
๐ถ Veterinary products
None
Acid dissociation constants calculated using MoKa v3.0.0
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Dissociation level
Dissociation constant
Type (acidic/basic)
pKa1
8.13
Basic
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Orange Book patent data (new drug applications)
None
Orange Book exclusivity data (new drug applications)
None
Bioactivity Summary:
None
External reference:
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ID
Source
006845
NDDF
006846
NDDF
22503
RXNORM
3029
INN_ID
3321-06-0
SECONDARY_CAS_RN
71130
PUBCHEM_CID
C001967
MESH_SUPPLEMENTAL_RECORD_UI
C0057383
UMLSCUI
CHEBI:135601
CHEBI
CHEMBL1614656
ChEMBL_ID
Showing 1 to 10 of 12 entries
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Pharmaceutical products:
None
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denaverine