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algestone acetophenide 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | PK/Tox | Related Drugs | BioActivity |
| Stem definition | Drug id | CAS RN |
|---|---|---|
| corticosteroids, except prednisolone derivatives | 797 | 24356-94-3 |
Description:
| Molecule | Description |
|---|---|
|
Synonyms:
|
A progesterone that has been used in ESTRUS SYNCHRONIZATION and has been evaluated as an injectable contraceptive in combination with estradiol enanthate. It is also applied topically as an anti-inflammatory and in the treatment of ACNE.
|
Drug dosage:
None
ADMET properties:
None
Predicted pharmacokinetic/toxicological properties (PK-AZ):
| Property | Description | Value | Unit | Confidence | Similarity |
|---|---|---|---|---|---|
| kinase-safety-class | ACVR2B,AXL,BRAF,CAMK2D,CDK5,EIF2AK3,ERBB2,GRK2,ITK,MAPK10,NTRK2,PDK1,PDK2,PDK4,PRKDC | 15 | |||
| kinase-selectivity-class | EIF2AK3,GRK2 | 2 | |||
| pfas-class | PFAS structural alert (1 = True, 0 = False) | 0 |
Approvals:
None
FDA Adverse Event Reporting System (Female)
None
FDA Adverse Event Reporting System (Male)
None
FDA Adverse Event Reporting System (Geriatric)
| MedDRA adverse event term | Likelihood ratio | Likelihood ratio threshold | Patients taking drug having adverse event | Patients taking drug not having adverse event | Patients not taking drug having adverse event | Patients not taking drug not having adverse event |
|---|---|---|---|---|---|---|
| Lupus nephritis | 35.53 | 32.70 | 4 | 3 | 4641 | 110584651 |
FDA Adverse Event Reporting System (Pediatric)
None
Pharmacologic Action:
| Source | Code | Description |
|---|---|---|
| MeSH PA | D000080066 | Contraceptive Agents, Hormonal |
| MeSH PA | D000893 | Anti-Inflammatory Agents |
| MeSH PA | D003271 | Contraceptive Agents, Female |
| MeSH PA | D003280 | Contraceptives, Oral, Synthetic |
| MeSH PA | D006728 | Hormones |
| MeSH PA | D011372 | Progestins |
| MeSH PA | D012102 | Reproductive Control Agents |
| CHEBI has role | CHEBI:35472 | anti-inflammatory drug |
| CHEBI has role | CHEBI:49326 | synthetic oral contraceptive |
Drug Use | Suggest Off label Use Form| |View source of the data|
None
🐶 Veterinary Drug Use
None
🐶 Veterinary products
None
Acid dissociation constants calculated using MoKa v3.0.0
None
Orange Book patent data (new drug applications)
None
Orange Book exclusivity data (new drug applications)
None
Bioactivity Summary:
None
External reference:
| ID | Source |
|---|---|
| D02809 | KEGG_DRUG |
| CHEMBL3989742 | ChEMBL_ID |
| DB15775 | DRUGBANK_ID |
| 32887 | MMSL |
| 006143 | NDDF |
| 490911000221103 | SNOMEDCT_US |
| C0002039 | UMLSCUI |
| D000463 | MESH_DESCRIPTOR_UI |
| CHEBI:49327 | CHEBI |
| 5284538 | PUBCHEM_CID |
| OL7KC2O3OT | UNII |
Pharmaceutical products:
None