Stem definition | Drug id | CAS RN |
---|---|---|
corticosteroids, except prednisolone derivatives | 734 | 50-04-4 |
None
Property | Value | Reference |
---|---|---|
BDDCS (Biopharmaceutical Drug Disposition Classification System) | 1 | Benet LZ, Broccatelli F, Oprea TI |
S (Water solubility) | 0.28 mg/mL | Benet LZ, Broccatelli F, Oprea TI |
MRTD (Maximum Recommended Therapeutic Daily Dose) | 13.87 ยตM/kg/day | Contrera JF, Matthews EJ, Kruhlak NL, Benz RD |
Date | Agency | Company | Orphan |
---|---|---|---|
June 13, 1950 | FDA |
MedDRA adverse event term | Likelihood ratio | Likelihood ratio threshold | Patients taking drug having adverse event | Patients taking drug not having adverse event | Patients not taking drug having adverse event | Patients not taking drug not having adverse event |
---|---|---|---|---|---|---|
Pemphigus | 3758.07 | 69.05 | 3023 | 123256 | 180703 | 63182040 |
Systemic lupus erythematosus | 3529.49 | 69.05 | 3078 | 123201 | 205840 | 63156903 |
Glossodynia | 3325.02 | 69.05 | 2785 | 123494 | 176091 | 63186652 |
Hand deformity | 3106.61 | 69.05 | 2552 | 123727 | 156905 | 63205838 |
Wound | 2956.56 | 69.05 | 2505 | 123774 | 160758 | 63201985 |
Pericarditis | 2491.90 | 69.05 | 2073 | 124206 | 129506 | 63233237 |
Abdominal discomfort | 2445.92 | 69.05 | 3090 | 123189 | 317795 | 63044948 |
Alopecia | 2379.50 | 69.05 | 3127 | 123152 | 334409 | 63028334 |
Discomfort | 2324.07 | 69.05 | 2212 | 124067 | 165162 | 63197581 |
Swelling | 2321.68 | 69.05 | 2791 | 123488 | 272587 | 63090156 |
Anti-cyclic citrullinated peptide antibody positive | 2222.67 | 69.05 | 1842 | 124437 | 114370 | 63248373 |
Arthropathy | 2165.96 | 69.05 | 2493 | 123786 | 232299 | 63130444 |
Contraindicated product administered | 1991.56 | 69.05 | 2302 | 123977 | 215346 | 63147397 |
Synovitis | 1903.94 | 69.05 | 2091 | 124188 | 184827 | 63177916 |
Maternal exposure during pregnancy | 1745.67 | 69.05 | 2165 | 124114 | 217897 | 63144846 |
Rheumatoid factor positive | 1618.83 | 69.05 | 1341 | 124938 | 83065 | 63279678 |
Infusion related reaction | 1515.23 | 69.05 | 2136 | 124143 | 243385 | 63119358 |
Hepatic enzyme increased | 1454.10 | 69.05 | 1896 | 124383 | 200432 | 63162311 |
Duodenal ulcer perforation | 1452.63 | 69.05 | 1278 | 125001 | 85931 | 63276812 |
Helicobacter infection | 1363.08 | 69.05 | 1267 | 125012 | 91518 | 63271225 |
Product use issue | 1348.81 | 69.05 | 1911 | 124368 | 218609 | 63144134 |
Hypersensitivity | 1249.62 | 69.05 | 2149 | 124130 | 290536 | 63072207 |
Drug intolerance | 1180.74 | 69.05 | 2160 | 124119 | 306501 | 63056242 |
Treatment failure | 1097.30 | 69.05 | 1643 | 124636 | 197400 | 63165343 |
Rheumatic fever | 940.17 | 69.05 | 739 | 125540 | 42372 | 63320371 |
Swollen joint count increased | 849.23 | 69.05 | 647 | 125632 | 35407 | 63327336 |
Joint swelling | 846.69 | 69.05 | 1951 | 124328 | 325715 | 63037028 |
Pain | 760.51 | 69.05 | 3191 | 123088 | 737437 | 62625306 |
Therapeutic product effect decreased | 749.56 | 69.05 | 1362 | 124917 | 191825 | 63170918 |
Type 2 diabetes mellitus | 660.97 | 69.05 | 722 | 125557 | 63146 | 63299597 |
Blood cholesterol increased | 647.04 | 69.05 | 864 | 125415 | 93168 | 63269575 |
Blister | 639.05 | 69.05 | 1018 | 125261 | 128796 | 63233947 |
Death | 630.13 | 69.05 | 27 | 126252 | 374354 | 62988389 |
Fall | 617.79 | 69.05 | 42 | 126237 | 392292 | 62970451 |
Hip arthroplasty | 606.79 | 69.05 | 602 | 125677 | 47044 | 63315699 |
Rash | 600.98 | 69.05 | 2451 | 123828 | 558420 | 62804323 |
Anaemia | 494.07 | 69.05 | 21 | 126258 | 293409 | 63069334 |
Knee arthroplasty | 492.85 | 69.05 | 573 | 125706 | 53633 | 63309110 |
Folliculitis | 486.43 | 69.05 | 648 | 125631 | 69669 | 63293074 |
General physical health deterioration | 479.46 | 69.05 | 1163 | 125116 | 200239 | 63162504 |
Toxicity to various agents | 469.48 | 69.05 | 4 | 126275 | 247246 | 63115497 |
Muscle injury | 457.85 | 69.05 | 606 | 125673 | 64739 | 63298004 |
Musculoskeletal stiffness | 430.70 | 69.05 | 1058 | 125221 | 183560 | 63179183 |
Irritable bowel syndrome | 425.59 | 69.05 | 661 | 125618 | 81751 | 63280992 |
Intentional product use issue | 415.60 | 69.05 | 837 | 125442 | 127055 | 63235688 |
Hypotension | 415.08 | 69.05 | 34 | 126245 | 272570 | 63090173 |
Sleep disorder due to general medical condition, insomnia type | 406.12 | 69.05 | 510 | 125769 | 51707 | 63311036 |
Urinary tract infection | 403.02 | 69.05 | 33 | 126246 | 264651 | 63098092 |
Nausea | 400.80 | 69.05 | 680 | 125599 | 853791 | 62508952 |
Liver injury | 394.61 | 69.05 | 542 | 125737 | 59978 | 63302765 |
Drug interaction | 386.92 | 69.05 | 16 | 126263 | 229115 | 63133628 |
Constipation | 382.22 | 69.05 | 15 | 126264 | 224928 | 63137815 |
Impaired healing | 358.31 | 69.05 | 692 | 125587 | 101850 | 63260893 |
Back pain | 347.14 | 69.05 | 55 | 126224 | 264090 | 63098653 |
Neutropenia | 314.20 | 69.05 | 7 | 126272 | 174998 | 63187745 |
Somnolence | 313.79 | 69.05 | 9 | 126270 | 178676 | 63184067 |
Cough | 298.31 | 69.05 | 105 | 126174 | 292638 | 63070105 |
Diarrhoea | 297.15 | 69.05 | 612 | 125667 | 714754 | 62647989 |
Dehydration | 296.35 | 69.05 | 11 | 126268 | 173343 | 63189400 |
Psoriatic arthropathy | 284.14 | 69.05 | 588 | 125691 | 90932 | 63271811 |
Sepsis | 267.79 | 69.05 | 8 | 126271 | 153115 | 63209628 |
Erythema | 264.40 | 69.05 | 23 | 126256 | 175728 | 63187015 |
Product dose omission issue | 263.96 | 69.05 | 70 | 126209 | 234243 | 63128500 |
Ill-defined disorder | 262.92 | 69.05 | 533 | 125746 | 81222 | 63281521 |
Fatigue | 257.86 | 69.05 | 2794 | 123485 | 885234 | 62477509 |
Drug ineffective | 255.90 | 69.05 | 3180 | 123099 | 1041585 | 62321158 |
Fibromyalgia | 255.89 | 69.05 | 522 | 125757 | 79898 | 63282845 |
Injury | 255.38 | 69.05 | 494 | 125785 | 72753 | 63289990 |
Prescribed overdose | 247.24 | 69.05 | 322 | 125957 | 33831 | 63328912 |
Feeling abnormal | 245.04 | 69.05 | 12 | 126267 | 148380 | 63214363 |
Seizure | 243.32 | 69.05 | 4 | 126275 | 132630 | 63230113 |
Haemoglobin decreased | 239.48 | 69.05 | 12 | 126267 | 145473 | 63217270 |
Blood pressure increased | 236.35 | 69.05 | 24 | 126255 | 162038 | 63200705 |
Tremor | 234.60 | 69.05 | 6 | 126273 | 132233 | 63230510 |
Live birth | 231.27 | 69.05 | 270 | 126009 | 25360 | 63337383 |
White blood cell count decreased | 224.20 | 69.05 | 13 | 126266 | 139091 | 63223652 |
Disease progression | 223.95 | 69.05 | 4 | 126275 | 122754 | 63239989 |
Asthenia | 219.80 | 69.05 | 264 | 126015 | 383340 | 62979403 |
Febrile neutropenia | 215.50 | 69.05 | 4 | 126275 | 118445 | 63244298 |
Thrombocytopenia | 213.77 | 69.05 | 25 | 126254 | 151132 | 63211611 |
Condition aggravated | 210.42 | 69.05 | 1444 | 124835 | 400773 | 62961970 |
Adverse event | 209.56 | 69.05 | 434 | 125845 | 67125 | 63295618 |
Mobility decreased | 208.40 | 69.05 | 621 | 125658 | 120538 | 63242205 |
Pneumonia | 207.29 | 69.05 | 370 | 125909 | 456397 | 62906346 |
Platelet count decreased | 207.00 | 69.05 | 5 | 126274 | 116117 | 63246626 |
Neuropathy peripheral | 202.22 | 69.05 | 5 | 126274 | 113662 | 63249081 |
Renal failure | 199.20 | 69.05 | 8 | 126271 | 117644 | 63245099 |
Myalgia | 195.80 | 69.05 | 29 | 126250 | 146500 | 63216243 |
Injection site pain | 195.16 | 69.05 | 17 | 126262 | 129783 | 63232960 |
Dyspnoea | 190.99 | 69.05 | 676 | 125603 | 660637 | 62702106 |
Stomatitis | 190.36 | 69.05 | 658 | 125621 | 138067 | 63224676 |
Pulmonary embolism | 187.74 | 69.05 | 11 | 126268 | 116673 | 63246070 |
Cerebrovascular accident | 187.56 | 69.05 | 6 | 126273 | 108018 | 63254725 |
Syncope | 186.05 | 69.05 | 12 | 126267 | 117373 | 63245370 |
Respiratory failure | 183.05 | 69.05 | 4 | 126275 | 101854 | 63260889 |
Pancytopenia | 177.45 | 69.05 | 3 | 126276 | 96930 | 63265813 |
Alanine aminotransferase increased | 175.87 | 69.05 | 7 | 126272 | 103763 | 63258980 |
Chills | 175.59 | 69.05 | 13 | 126266 | 113365 | 63249378 |
Myocardial infarction | 171.83 | 69.05 | 6 | 126273 | 99887 | 63262856 |
Lower respiratory tract infection | 164.78 | 69.05 | 608 | 125671 | 131699 | 63231044 |
Palpitations | 163.61 | 69.05 | 17 | 126262 | 112753 | 63249990 |
Hyperhidrosis | 162.44 | 69.05 | 14 | 126265 | 107822 | 63254921 |
Cardiac failure | 162.19 | 69.05 | 3 | 126276 | 89139 | 63273604 |
Blood creatinine increased | 159.64 | 69.05 | 3 | 126276 | 87841 | 63274902 |
Aspartate aminotransferase increased | 156.78 | 69.05 | 5 | 126274 | 90272 | 63272471 |
COVID-19 | 156.72 | 69.05 | 20 | 126259 | 113083 | 63249660 |
Anxiety | 156.62 | 69.05 | 122 | 126157 | 217419 | 63145324 |
Adjustment disorder with depressed mood | 154.60 | 69.05 | 142 | 126137 | 10062 | 63352681 |
Vision blurred | 153.12 | 69.05 | 7 | 126272 | 91917 | 63270826 |
Renal impairment | 153.06 | 69.05 | 5 | 126274 | 88350 | 63274393 |
Deep vein thrombosis postoperative | 152.72 | 69.05 | 148 | 126131 | 11221 | 63351522 |
Drug tolerance decreased | 152.53 | 69.05 | 181 | 126098 | 17292 | 63345451 |
Infection | 151.47 | 69.05 | 874 | 125405 | 228299 | 63134444 |
Heart rate increased | 151.24 | 69.05 | 9 | 126270 | 94229 | 63268514 |
Lip dry | 148.01 | 69.05 | 168 | 126111 | 15302 | 63347441 |
Foot deformity | 147.26 | 69.05 | 226 | 126053 | 27627 | 63335116 |
Vomiting | 146.48 | 69.05 | 595 | 125684 | 559022 | 62803721 |
Facet joint syndrome | 146.38 | 69.05 | 149 | 126130 | 11989 | 63350754 |
Balance disorder | 145.45 | 69.05 | 5 | 126274 | 84417 | 63278326 |
Cellulitis | 144.28 | 69.05 | 4 | 126275 | 81954 | 63280789 |
Loss of consciousness | 143.36 | 69.05 | 30 | 126249 | 118091 | 63244652 |
Chest discomfort | 141.84 | 69.05 | 24 | 126255 | 109945 | 63252798 |
Oropharyngeal pain | 140.33 | 69.05 | 13 | 126266 | 94474 | 63268269 |
Dislocation of vertebra | 140.33 | 69.05 | 125 | 126154 | 8510 | 63354233 |
Injection site erythema | 139.63 | 69.05 | 6 | 126273 | 83168 | 63279575 |
Retinitis | 138.79 | 69.05 | 108 | 126171 | 6088 | 63356655 |
Adverse drug reaction | 138.34 | 69.05 | 410 | 125869 | 79304 | 63283439 |
Inappropriate schedule of product administration | 137.89 | 69.05 | 21 | 126258 | 103944 | 63258799 |
Dysphagia | 137.61 | 69.05 | 10 | 126269 | 88575 | 63274168 |
Oxygen saturation decreased | 137.61 | 69.05 | 10 | 126269 | 88575 | 63274168 |
Malignant neoplasm progression | 137.61 | 69.05 | 6 | 126273 | 82115 | 63280628 |
Deep vein thrombosis | 137.59 | 69.05 | 7 | 126272 | 83793 | 63278950 |
Influenza | 135.31 | 69.05 | 26 | 126253 | 108696 | 63254047 |
Blood glucose increased | 134.40 | 69.05 | 8 | 126271 | 83748 | 63278995 |
Leukopenia | 131.69 | 69.05 | 5 | 126274 | 77285 | 63285458 |
Tachycardia | 131.63 | 69.05 | 36 | 126243 | 118120 | 63244623 |
Prescribed underdose | 131.15 | 69.05 | 222 | 126057 | 29467 | 63333276 |
Anti-cyclic citrullinated peptide antibody | 130.53 | 69.05 | 108 | 126171 | 6650 | 63356093 |
Weight decreased | 130.10 | 69.05 | 219 | 126060 | 276579 | 63086164 |
Herpes zoster | 128.99 | 69.05 | 9 | 126270 | 82453 | 63280290 |
Overdose | 128.31 | 69.05 | 35 | 126244 | 115043 | 63247700 |
Abdominal pain | 128.20 | 69.05 | 243 | 126036 | 293213 | 63069530 |
Flushing | 127.45 | 69.05 | 5 | 126274 | 75082 | 63287661 |
Bradycardia | 127.35 | 69.05 | 4 | 126275 | 73223 | 63289520 |
Grip strength decreased | 126.59 | 69.05 | 187 | 126092 | 22100 | 63340643 |
Exposure during pregnancy | 125.68 | 69.05 | 627 | 125652 | 154920 | 63207823 |
Bronchitis | 121.73 | 69.05 | 48 | 126231 | 124887 | 63237856 |
Gastrointestinal disorder | 121.26 | 69.05 | 550 | 125729 | 130689 | 63232054 |
Stress | 119.27 | 69.05 | 3 | 126276 | 67164 | 63295579 |
Anaphylactic reaction | 117.20 | 69.05 | 3 | 126276 | 66097 | 63296646 |
Epistaxis | 116.53 | 69.05 | 7 | 126272 | 72718 | 63290025 |
Peripheral venous disease | 115.23 | 69.05 | 148 | 126131 | 15329 | 63347414 |
Coma | 113.82 | 69.05 | 3 | 126276 | 64361 | 63298382 |
Insomnia | 111.93 | 69.05 | 159 | 126120 | 215093 | 63147650 |
Autoimmune disorder | 110.61 | 69.05 | 153 | 126126 | 17024 | 63345719 |
Hypokalaemia | 109.46 | 69.05 | 35 | 126244 | 103769 | 63258974 |
Interstitial lung disease | 109.05 | 69.05 | 3 | 126276 | 61905 | 63300838 |
Nerve injury | 109.00 | 69.05 | 116 | 126163 | 9830 | 63352913 |
Gastrooesophageal reflux disease | 108.68 | 69.05 | 28 | 126251 | 95611 | 63267132 |
Blood pressure decreased | 108.13 | 69.05 | 5 | 126274 | 65017 | 63297726 |
Dizziness | 108.06 | 69.05 | 464 | 125815 | 429461 | 62933282 |
Suicide attempt | 107.13 | 69.05 | 3 | 126276 | 60915 | 63301828 |
Chronic obstructive pulmonary disease | 106.98 | 69.05 | 4 | 126275 | 62682 | 63300061 |
Depression | 106.32 | 69.05 | 141 | 126138 | 196351 | 63166392 |
Rash pruritic | 104.95 | 69.05 | 3 | 126276 | 59796 | 63302947 |
Swelling face | 102.03 | 69.05 | 6 | 126273 | 63469 | 63299274 |
Hypoglycaemia | 98.65 | 69.05 | 5 | 126274 | 60060 | 63302683 |
X-ray abnormal | 98.60 | 69.05 | 100 | 126179 | 8010 | 63354733 |
Lupus vulgaris | 97.86 | 69.05 | 87 | 126192 | 5907 | 63356836 |
Nasal congestion | 97.58 | 69.05 | 9 | 126270 | 65651 | 63297092 |
Rhinorrhoea | 94.81 | 69.05 | 10 | 126269 | 65567 | 63297176 |
Suicidal ideation | 94.27 | 69.05 | 8 | 126271 | 62413 | 63300330 |
Lethargy | 94.14 | 69.05 | 4 | 126275 | 56003 | 63306740 |
Pulmonary fibrosis | 93.47 | 69.05 | 229 | 126050 | 39580 | 63323163 |
Thrombosis | 93.30 | 69.05 | 10 | 126269 | 64745 | 63297998 |
Dry skin | 92.60 | 69.05 | 5 | 126274 | 56882 | 63305861 |
Systemic lupus erythematosus rash | 92.48 | 69.05 | 57 | 126222 | 2195 | 63360548 |
Abdominal distension | 89.92 | 69.05 | 30 | 126249 | 86585 | 63276158 |
Haematochezia | 89.41 | 69.05 | 4 | 126275 | 53540 | 63309203 |
Hot flush | 88.22 | 69.05 | 3 | 126276 | 51156 | 63311587 |
Cardiac disorder | 87.56 | 69.05 | 3 | 126276 | 50813 | 63311930 |
Pleural effusion | 87.25 | 69.05 | 38 | 126241 | 93172 | 63269571 |
Cystitis | 86.00 | 69.05 | 6 | 126273 | 54985 | 63307758 |
Hallucination | 85.67 | 69.05 | 6 | 126273 | 54811 | 63307932 |
Productive cough | 85.58 | 69.05 | 12 | 126267 | 63196 | 63299547 |
Joint range of motion decreased | 85.31 | 69.05 | 195 | 126084 | 32233 | 63330510 |
Breast cancer | 82.86 | 69.05 | 3 | 126276 | 48380 | 63314363 |
Liver function test abnormal | 82.47 | 69.05 | 3 | 126276 | 48178 | 63314565 |
Unevaluable event | 82.16 | 69.05 | 5 | 126274 | 51381 | 63311362 |
Angioedema | 82.06 | 69.05 | 3 | 126276 | 47962 | 63314781 |
Cataract | 81.71 | 69.05 | 9 | 126270 | 57044 | 63305699 |
Multiple organ dysfunction syndrome | 81.16 | 69.05 | 9 | 126270 | 56743 | 63306000 |
Contusion | 80.69 | 69.05 | 543 | 125736 | 149501 | 63213242 |
Colitis | 79.82 | 69.05 | 4 | 126275 | 48524 | 63314219 |
Upper respiratory tract infection | 79.13 | 69.05 | 32 | 126247 | 82015 | 63280728 |
Vertigo | 77.36 | 69.05 | 13 | 126266 | 59874 | 63302869 |
Haemorrhage | 77.18 | 69.05 | 14 | 126265 | 61008 | 63301735 |
Agitation | 77.13 | 69.05 | 13 | 126266 | 59744 | 63302999 |
Breast cancer stage III | 76.82 | 69.05 | 99 | 126180 | 10287 | 63352456 |
Malaise | 75.45 | 69.05 | 501 | 125778 | 415453 | 62947290 |
Pulmonary oedema | 75.28 | 69.05 | 10 | 126269 | 54863 | 63307880 |
Dysphonia | 75.03 | 69.05 | 5 | 126274 | 47609 | 63315134 |
Oedema | 74.23 | 69.05 | 387 | 125892 | 97235 | 63265508 |
International normalised ratio increased | 72.79 | 69.05 | 5 | 126274 | 46420 | 63316323 |
Blood alkaline phosphatase increased | 72.44 | 69.05 | 3 | 126276 | 42964 | 63319779 |
Blood pressure systolic increased | 71.78 | 69.05 | 6 | 126273 | 47391 | 63315352 |
Multiple sclerosis relapse | 71.09 | 69.05 | 7 | 126272 | 48471 | 63314272 |
Mucosal inflammation | 70.90 | 69.05 | 6 | 126273 | 46922 | 63315821 |
Wound infection | 70.44 | 69.05 | 141 | 126138 | 21269 | 63341474 |
Burning sensation | 69.86 | 69.05 | 12 | 126267 | 54395 | 63308348 |
Rectal haemorrhage | 69.55 | 69.05 | 8 | 126271 | 49022 | 63313721 |
MedDRA adverse event term | Likelihood ratio | Likelihood ratio threshold | Patients taking drug having adverse event | Patients taking drug not having adverse event | Patients not taking drug having adverse event | Patients not taking drug not having adverse event |
---|---|---|---|---|---|---|
Onychoclasis | 149.50 | 24.23 | 33 | 2400 | 1867 | 34952631 |
Tooth loss | 126.26 | 24.23 | 33 | 2400 | 3825 | 34950673 |
Lymphoma | 91.71 | 24.23 | 34 | 2399 | 12473 | 34942025 |
Neoplasm malignant | 79.65 | 24.23 | 35 | 2398 | 19870 | 34934628 |
Alopecia | 55.20 | 24.23 | 29 | 2404 | 24326 | 34930172 |
Osteonecrosis of jaw | 48.36 | 24.23 | 24 | 2409 | 17865 | 34936633 |
Drug intolerance | 46.17 | 24.23 | 36 | 2397 | 59534 | 34894964 |
Administration site discomfort | 45.85 | 24.23 | 7 | 2426 | 46 | 34954452 |
Contraindicated product administered | 41.46 | 24.23 | 23 | 2410 | 21458 | 34933040 |
Genital herpes simplex | 39.63 | 24.23 | 7 | 2426 | 122 | 34954376 |
Suture rupture | 37.82 | 24.23 | 8 | 2425 | 368 | 34954130 |
Drug tolerance decreased | 33.07 | 24.23 | 10 | 2423 | 1957 | 34952541 |
Drug ineffective | 30.98 | 24.23 | 85 | 2348 | 456666 | 34497832 |
Lymphocele | 27.62 | 24.23 | 8 | 2425 | 1349 | 34953149 |
Soft tissue disorder | 27.35 | 24.23 | 7 | 2426 | 743 | 34953755 |
Elbow operation | 26.25 | 24.23 | 5 | 2428 | 134 | 34954364 |
Autoimmune disorder | 25.42 | 24.23 | 8 | 2425 | 1786 | 34952712 |
Synovitis | 24.26 | 24.23 | 14 | 2419 | 14052 | 34940446 |
MedDRA adverse event term | Likelihood ratio | Likelihood ratio threshold | Patients taking drug having adverse event | Patients taking drug not having adverse event | Patients not taking drug having adverse event | Patients not taking drug not having adverse event |
---|---|---|---|---|---|---|
Pemphigus | 2782.39 | 52.38 | 1578 | 84445 | 98004 | 79560361 |
Systemic lupus erythematosus | 2606.89 | 52.38 | 1622 | 84401 | 119527 | 79538838 |
Glossodynia | 2451.53 | 52.38 | 1473 | 84550 | 101864 | 79556501 |
Hand deformity | 2374.16 | 52.38 | 1446 | 84577 | 102473 | 79555892 |
Pericarditis | 2189.44 | 52.38 | 1375 | 84648 | 102861 | 79555504 |
Wound | 2118.32 | 52.38 | 1402 | 84621 | 114777 | 79543588 |
Anti-cyclic citrullinated peptide antibody positive | 2006.76 | 52.38 | 1199 | 84824 | 81944 | 79576421 |
Alopecia | 1754.30 | 52.38 | 1664 | 84359 | 229691 | 79428674 |
Synovitis | 1746.76 | 52.38 | 1382 | 84641 | 149352 | 79509013 |
Arthropathy | 1689.13 | 52.38 | 1450 | 84573 | 175661 | 79482704 |
Discomfort | 1630.01 | 52.38 | 1232 | 84791 | 124385 | 79533980 |
Swelling | 1597.46 | 52.38 | 1535 | 84488 | 215176 | 79443189 |
Abdominal discomfort | 1557.38 | 52.38 | 1618 | 84405 | 249109 | 79409256 |
Contraindicated product administered | 1473.55 | 52.38 | 1276 | 84747 | 156262 | 79502103 |
Rheumatoid factor positive | 1461.25 | 52.38 | 870 | 85153 | 58969 | 79599396 |
Duodenal ulcer perforation | 1372.50 | 52.38 | 867 | 85156 | 65344 | 79593021 |
Maternal exposure during pregnancy | 1366.56 | 52.38 | 1150 | 84873 | 135388 | 79522977 |
Helicobacter infection | 1297.42 | 52.38 | 853 | 85170 | 68851 | 79589514 |
Hepatic enzyme increased | 1237.21 | 52.38 | 1236 | 84787 | 181374 | 79476991 |
Hypersensitivity | 1166.33 | 52.38 | 1423 | 84600 | 260816 | 79397549 |
Drug intolerance | 1150.06 | 52.38 | 1418 | 84605 | 262701 | 79395664 |
Infusion related reaction | 1068.48 | 52.38 | 1277 | 84746 | 228960 | 79429405 |
Joint swelling | 844.88 | 52.38 | 1279 | 84744 | 287367 | 79370998 |
Therapeutic product effect decreased | 841.38 | 52.38 | 958 | 85065 | 162905 | 79495460 |
Treatment failure | 818.81 | 52.38 | 963 | 85060 | 169523 | 79488842 |
Rheumatic fever | 802.47 | 52.38 | 455 | 85568 | 28070 | 79630295 |
Blister | 801.26 | 52.38 | 805 | 85218 | 118671 | 79539694 |
Product use issue | 782.28 | 52.38 | 1044 | 84979 | 208778 | 79449587 |
Swollen joint count increased | 672.73 | 52.38 | 376 | 85647 | 22551 | 79635814 |
Folliculitis | 640.27 | 52.38 | 508 | 85515 | 54872 | 79603493 |
Hip arthroplasty | 612.72 | 52.38 | 416 | 85607 | 35340 | 79623025 |
Irritable bowel syndrome | 610.74 | 52.38 | 519 | 85504 | 61722 | 79596643 |
Muscle injury | 608.05 | 52.38 | 467 | 85556 | 48094 | 79610271 |
Blood cholesterol increased | 566.27 | 52.38 | 567 | 85456 | 83153 | 79575212 |
Sleep disorder due to general medical condition, insomnia type | 545.58 | 52.38 | 419 | 85604 | 43137 | 79615228 |
Type 2 diabetes mellitus | 537.36 | 52.38 | 465 | 85558 | 56657 | 79601708 |
Acute kidney injury | 533.50 | 52.38 | 5 | 86018 | 519399 | 79138966 |
Impaired healing | 528.35 | 52.38 | 558 | 85465 | 87097 | 79571268 |
Knee arthroplasty | 506.87 | 52.38 | 400 | 85623 | 42848 | 79615517 |
Death | 483.75 | 52.38 | 33 | 85990 | 566481 | 79091884 |
Fibromyalgia | 461.43 | 52.38 | 450 | 85573 | 63890 | 79594475 |
Pain | 461.25 | 52.38 | 1732 | 84291 | 702070 | 78956295 |
Liver injury | 449.74 | 52.38 | 419 | 85604 | 56195 | 79602170 |
Toxicity to various agents | 428.36 | 52.38 | 5 | 86018 | 421535 | 79236830 |
Anaemia | 414.33 | 52.38 | 15 | 86008 | 445000 | 79213365 |
Musculoskeletal stiffness | 411.59 | 52.38 | 703 | 85320 | 174305 | 79484060 |
Psoriatic arthropathy | 404.68 | 52.38 | 459 | 85564 | 77540 | 79580825 |
Rash | 382.98 | 52.38 | 1429 | 84594 | 576929 | 79081436 |
Fall | 364.44 | 52.38 | 48 | 85975 | 487581 | 79170784 |
Ill-defined disorder | 359.40 | 52.38 | 398 | 85625 | 65477 | 79592888 |
Drug interaction | 348.90 | 52.38 | 26 | 85997 | 415157 | 79243208 |
Hypotension | 344.67 | 52.38 | 37 | 85986 | 440280 | 79218085 |
Intentional product use issue | 312.36 | 52.38 | 576 | 85447 | 151536 | 79506829 |
Injury | 307.23 | 52.38 | 398 | 85625 | 77098 | 79581267 |
General physical health deterioration | 293.33 | 52.38 | 802 | 85221 | 274436 | 79383929 |
Stomatitis | 291.65 | 52.38 | 548 | 85475 | 146209 | 79512156 |
Neutropenia | 273.63 | 52.38 | 8 | 86015 | 287702 | 79370663 |
Adverse event | 268.50 | 52.38 | 328 | 85695 | 59886 | 79598479 |
Mobility decreased | 263.90 | 52.38 | 473 | 85550 | 121702 | 79536663 |
Prescribed overdose | 262.25 | 52.38 | 260 | 85763 | 37623 | 79620742 |
Exposure during pregnancy | 249.11 | 52.38 | 415 | 85608 | 100717 | 79557648 |
Foot deformity | 248.85 | 52.38 | 207 | 85816 | 23867 | 79634498 |
Constipation | 242.64 | 52.38 | 16 | 86007 | 283034 | 79375331 |
Lower respiratory tract infection | 242.50 | 52.38 | 471 | 85552 | 128749 | 79529616 |
Completed suicide | 240.66 | 52.38 | 5 | 86018 | 245762 | 79412603 |
Infection | 240.37 | 52.38 | 687 | 85336 | 241025 | 79417340 |
Sepsis | 225.82 | 52.38 | 17 | 86006 | 269411 | 79388954 |
Febrile neutropenia | 224.99 | 52.38 | 5 | 86018 | 230994 | 79427371 |
Deep vein thrombosis postoperative | 222.90 | 52.38 | 141 | 85882 | 10611 | 79647754 |
Pneumonia | 220.23 | 52.38 | 233 | 85790 | 660013 | 78998352 |
Lip dry | 218.97 | 52.38 | 160 | 85863 | 15258 | 79643107 |
Facet joint syndrome | 218.91 | 52.38 | 142 | 85881 | 11160 | 79647205 |
Thrombocytopenia | 216.03 | 52.38 | 19 | 86004 | 265240 | 79393125 |
Dehydration | 215.78 | 52.38 | 13 | 86010 | 248174 | 79410191 |
Somnolence | 206.31 | 52.38 | 13 | 86010 | 238968 | 79419397 |
Live birth | 205.94 | 52.38 | 167 | 85856 | 18577 | 79639788 |
Adjustment disorder with depressed mood | 198.02 | 52.38 | 123 | 85900 | 8963 | 79649402 |
Urinary tract infection | 193.33 | 52.38 | 32 | 85991 | 274480 | 79383885 |
Autoimmune disorder | 193.14 | 52.38 | 153 | 85870 | 16459 | 79641906 |
Gastrointestinal disorder | 189.77 | 52.38 | 412 | 85611 | 121793 | 79536572 |
Back pain | 184.51 | 52.38 | 50 | 85973 | 304130 | 79354235 |
Adverse drug reaction | 181.89 | 52.38 | 286 | 85737 | 66106 | 79592259 |
Erythema | 181.78 | 52.38 | 16 | 86007 | 223274 | 79435091 |
Nausea | 177.55 | 52.38 | 492 | 85531 | 956704 | 78701661 |
Seizure | 176.78 | 52.38 | 6 | 86017 | 188828 | 79469537 |
Grip strength decreased | 173.83 | 52.38 | 162 | 85861 | 21707 | 79636658 |
Renal failure | 173.25 | 52.38 | 11 | 86012 | 200957 | 79457408 |
Myocardial infarction | 171.84 | 52.38 | 6 | 86017 | 184123 | 79474242 |
Peripheral venous disease | 171.11 | 52.38 | 140 | 85883 | 15769 | 79642596 |
Haemoglobin decreased | 170.22 | 52.38 | 20 | 86003 | 222099 | 79436266 |
Disease progression | 168.66 | 52.38 | 7 | 86016 | 184355 | 79474010 |
Dislocation of vertebra | 167.51 | 52.38 | 105 | 85918 | 7775 | 79650590 |
Retinitis | 166.69 | 52.38 | 93 | 85930 | 5550 | 79652815 |
Respiratory failure | 165.07 | 52.38 | 7 | 86016 | 180904 | 79477461 |
Platelet count decreased | 163.87 | 52.38 | 12 | 86011 | 194652 | 79463713 |
Anti-cyclic citrullinated peptide antibody | 163.53 | 52.38 | 93 | 85930 | 5759 | 79652606 |
Cardiac arrest | 162.76 | 52.38 | 5 | 86018 | 172091 | 79486274 |
Condition aggravated | 159.42 | 52.38 | 1004 | 85019 | 500120 | 79158245 |
Hyponatraemia | 158.63 | 52.38 | 8 | 86015 | 177840 | 79480525 |
Drug ineffective | 158.43 | 52.38 | 1819 | 84204 | 1079094 | 78579271 |
Tremor | 153.79 | 52.38 | 7 | 86016 | 170076 | 79488289 |
Pancytopenia | 152.60 | 52.38 | 6 | 86017 | 165739 | 79492626 |
Pulmonary embolism | 146.16 | 52.38 | 10 | 86013 | 171644 | 79486721 |
Renal impairment | 144.29 | 52.38 | 6 | 86017 | 157777 | 79500588 |
White blood cell count decreased | 144.15 | 52.38 | 17 | 86006 | 188271 | 79470094 |
Osteoarthritis | 141.99 | 52.38 | 300 | 85723 | 87009 | 79571356 |
Cerebrovascular accident | 141.70 | 52.38 | 6 | 86017 | 155286 | 79503079 |
Cough | 140.27 | 52.38 | 114 | 85909 | 366675 | 79291690 |
Blood pressure increased | 139.43 | 52.38 | 29 | 85994 | 211331 | 79447034 |
Blood creatinine increased | 138.20 | 52.38 | 7 | 86016 | 155050 | 79503315 |
Fatigue | 137.97 | 52.38 | 1569 | 84454 | 928158 | 78730207 |
Joint range of motion decreased | 136.63 | 52.38 | 174 | 85849 | 33108 | 79625257 |
Cardiac failure | 134.87 | 52.38 | 8 | 86015 | 154834 | 79503531 |
Alanine aminotransferase increased | 134.07 | 52.38 | 11 | 86012 | 162559 | 79495806 |
Sinusitis | 133.60 | 52.38 | 489 | 85534 | 195012 | 79463353 |
Feeling abnormal | 133.45 | 52.38 | 10 | 86013 | 159189 | 79499176 |
Syncope | 133.00 | 52.38 | 18 | 86005 | 179431 | 79478934 |
Arthralgia | 133.00 | 52.38 | 1062 | 84961 | 570741 | 79087624 |
Contusion | 131.66 | 52.38 | 406 | 85617 | 148370 | 79509995 |
Gastrointestinal haemorrhage | 130.61 | 52.38 | 7 | 86016 | 147712 | 79510653 |
Hypoaesthesia | 129.69 | 52.38 | 457 | 85566 | 178895 | 79479470 |
Neuropathy peripheral | 127.15 | 52.38 | 6 | 86017 | 141299 | 79517066 |
Chills | 126.36 | 52.38 | 13 | 86010 | 160221 | 79498144 |
Systemic lupus erythematosus rash | 125.82 | 52.38 | 54 | 85969 | 1806 | 79656559 |
Bradycardia | 118.07 | 52.38 | 7 | 86016 | 135550 | 79522815 |
Overdose | 117.99 | 52.38 | 27 | 85996 | 184179 | 79474186 |
Myalgia | 115.39 | 52.38 | 29 | 85994 | 185612 | 79472753 |
Breast cancer stage III | 115.29 | 52.38 | 91 | 85932 | 9735 | 79648630 |
Dyspnoea | 115.16 | 52.38 | 505 | 85518 | 856520 | 78801845 |
Hyperhidrosis | 112.72 | 52.38 | 15 | 86008 | 151477 | 79506888 |
Multiple organ dysfunction syndrome | 111.89 | 52.38 | 4 | 86019 | 120242 | 79538123 |
Obesity | 109.90 | 52.38 | 161 | 85862 | 34964 | 79623401 |
Product dose omission issue | 107.62 | 52.38 | 67 | 85956 | 247470 | 79410895 |
Aspartate aminotransferase increased | 107.39 | 52.38 | 12 | 86011 | 138629 | 79519736 |
Oedema | 107.33 | 52.38 | 328 | 85695 | 119252 | 79539113 |
COVID-19 | 105.29 | 52.38 | 21 | 86002 | 157653 | 79500712 |
Pregnancy | 104.92 | 52.38 | 137 | 85886 | 26714 | 79631651 |
Diarrhoea | 104.16 | 52.38 | 543 | 85480 | 879946 | 78778419 |
Hyperkalaemia | 102.46 | 52.38 | 5 | 86018 | 114393 | 79543972 |
Exostosis | 100.86 | 52.38 | 107 | 85916 | 16751 | 79641614 |
Oxygen saturation decreased | 100.38 | 52.38 | 11 | 86012 | 129036 | 79529329 |
Tachycardia | 99.09 | 52.38 | 34 | 85989 | 177734 | 79480631 |
Bursitis | 98.96 | 52.38 | 155 | 85868 | 35689 | 79622676 |
Wound infection | 97.79 | 52.38 | 125 | 85898 | 23866 | 79634499 |
Hypoxia | 97.60 | 52.38 | 3 | 86020 | 103240 | 79555125 |
Rhabdomyolysis | 97.48 | 52.38 | 3 | 86020 | 103128 | 79555237 |
Blood glucose increased | 96.99 | 52.38 | 7 | 86016 | 114968 | 79543397 |
Bone erosion | 95.82 | 52.38 | 107 | 85916 | 17740 | 79640625 |
Leukopenia | 95.73 | 52.38 | 8 | 86015 | 116505 | 79541860 |
Lupus-like syndrome | 93.82 | 52.38 | 94 | 85929 | 13763 | 79644602 |
Loss of consciousness | 93.82 | 52.38 | 32 | 85991 | 167911 | 79490454 |
Asthenia | 93.75 | 52.38 | 264 | 85759 | 511425 | 79146940 |
Dysphagia | 93.52 | 52.38 | 11 | 86012 | 122125 | 79536240 |
Joint dislocation | 93.44 | 52.38 | 103 | 85920 | 16836 | 79641529 |
Lower limb fracture | 93.12 | 52.38 | 120 | 85903 | 23095 | 79635270 |
Coma | 91.43 | 52.38 | 4 | 86019 | 100645 | 79557720 |
Cellulitis | 90.97 | 52.38 | 7 | 86016 | 109053 | 79549312 |
Sciatica | 90.79 | 52.38 | 143 | 85880 | 33079 | 79625286 |
Epistaxis | 90.68 | 52.38 | 8 | 86015 | 111507 | 79546858 |
Nasopharyngitis | 89.58 | 52.38 | 523 | 85500 | 253358 | 79405007 |
Injection site pain | 89.44 | 52.38 | 16 | 86007 | 129822 | 79528543 |
Nerve injury | 89.33 | 52.38 | 77 | 85946 | 9315 | 79649050 |
Hypoglycaemia | 89.22 | 52.38 | 5 | 86018 | 101589 | 79556776 |
C-reactive protein abnormal | 89.04 | 52.38 | 175 | 85848 | 48192 | 79610173 |
Malignant neoplasm progression | 88.96 | 52.38 | 19 | 86004 | 135971 | 79522394 |
C-reactive protein | 87.78 | 52.38 | 59 | 85964 | 4920 | 79653445 |
Vision blurred | 87.76 | 52.38 | 7 | 86016 | 105891 | 79552474 |
Deep vein thrombosis | 87.54 | 52.38 | 13 | 86010 | 120906 | 79537459 |
Heart rate increased | 87.35 | 52.38 | 13 | 86010 | 120711 | 79537654 |
Chest discomfort | 84.94 | 52.38 | 22 | 86001 | 138022 | 79520343 |
Laryngitis | 84.13 | 52.38 | 95 | 85928 | 15944 | 79642421 |
Herpes zoster | 80.47 | 52.38 | 5 | 86018 | 93078 | 79565287 |
Balance disorder | 77.98 | 52.38 | 8 | 86015 | 98849 | 79559516 |
Vomiting | 76.70 | 52.38 | 414 | 85609 | 665414 | 78992951 |
Night sweats | 76.68 | 52.38 | 172 | 85851 | 51923 | 79606442 |
Palpitations | 76.34 | 52.38 | 21 | 86002 | 126589 | 79531776 |
Suicide attempt | 76.32 | 52.38 | 3 | 86020 | 82929 | 79575436 |
Lethargy | 74.61 | 52.38 | 3 | 86020 | 81289 | 79577076 |
Maternal exposure timing unspecified | 73.08 | 52.38 | 56 | 85967 | 5736 | 79652629 |
Hunger | 71.84 | 52.38 | 54 | 85969 | 5374 | 79652991 |
Blood pressure decreased | 71.30 | 52.38 | 11 | 86012 | 99455 | 79558910 |
X-ray abnormal | 70.71 | 52.38 | 55 | 85968 | 5758 | 79652607 |
Inappropriate schedule of product administration | 70.35 | 52.38 | 28 | 85995 | 133600 | 79524765 |
Hypokalaemia | 69.80 | 52.38 | 34 | 85989 | 144006 | 79514359 |
Stress | 69.65 | 52.38 | 4 | 86019 | 79608 | 79578757 |
Influenza | 68.48 | 52.38 | 27 | 85996 | 129579 | 79528786 |
Hallucination | 67.47 | 52.38 | 7 | 86016 | 85738 | 79572627 |
Seronegative arthritis | 67.31 | 52.38 | 49 | 85974 | 4643 | 79653722 |
Walking aid user | 67.16 | 52.38 | 68 | 85955 | 10080 | 79648285 |
Agitation | 67.15 | 52.38 | 13 | 86010 | 99702 | 79558663 |
Chronic obstructive pulmonary disease | 67.14 | 52.38 | 7 | 86016 | 85412 | 79572953 |
Haematochezia | 66.83 | 52.38 | 8 | 86015 | 87637 | 79570728 |
International normalised ratio increased | 66.45 | 52.38 | 7 | 86016 | 84714 | 79573651 |
Wheezing | 65.94 | 52.38 | 275 | 85748 | 116389 | 79541976 |
Bunion operation | 65.59 | 52.38 | 28 | 85995 | 924 | 79657441 |
Pulmonary oedema | 65.02 | 52.38 | 9 | 86014 | 88245 | 79570120 |
Lupus vulgaris | 64.69 | 52.38 | 42 | 85981 | 3304 | 79655061 |
Rash pruritic | 64.56 | 52.38 | 3 | 86020 | 71626 | 79586739 |
Pleural effusion | 63.54 | 52.38 | 39 | 85984 | 145223 | 79513142 |
Colitis | 63.18 | 52.38 | 4 | 86019 | 73303 | 79585062 |
Hypercholesterolaemia | 62.54 | 52.38 | 99 | 85924 | 22996 | 79635369 |
Oropharyngeal pain | 62.53 | 52.38 | 20 | 86003 | 109333 | 79549032 |
Peripheral swelling | 60.93 | 52.38 | 498 | 85525 | 269119 | 79389246 |
Weight increased | 60.89 | 52.38 | 509 | 85514 | 276877 | 79381488 |
Suicidal ideation | 60.67 | 52.38 | 6 | 86017 | 76334 | 79582031 |
Injection site erythema | 59.97 | 52.38 | 7 | 86016 | 78190 | 79580175 |
Gait inability | 59.90 | 52.38 | 169 | 85854 | 58748 | 79599617 |
Abdominal pain | 59.40 | 52.38 | 218 | 85805 | 389351 | 79269014 |
Haemorrhage | 59.04 | 52.38 | 13 | 86010 | 91105 | 79567260 |
Chronic kidney disease | 58.88 | 52.38 | 3 | 86020 | 66151 | 79592214 |
Intentional product misuse | 58.85 | 52.38 | 15 | 86008 | 95150 | 79563215 |
Dry skin | 57.74 | 52.38 | 4 | 86019 | 67991 | 79590374 |
Mucosal inflammation | 57.38 | 52.38 | 7 | 86016 | 75573 | 79582792 |
Joint destruction | 57.21 | 52.38 | 49 | 85974 | 5876 | 79652489 |
Drug tolerance decreased | 56.68 | 52.38 | 70 | 85953 | 12908 | 79645457 |
Foot operation | 56.56 | 52.38 | 48 | 85975 | 5685 | 79652680 |
Blood bilirubin increased | 55.94 | 52.38 | 4 | 86019 | 66228 | 79592137 |
Swelling face | 55.55 | 52.38 | 6 | 86017 | 71206 | 79587159 |
Angioedema | 55.43 | 52.38 | 8 | 86015 | 76027 | 79582338 |
Therapy non-responder | 54.86 | 52.38 | 221 | 85802 | 92084 | 79566281 |
Gastrooesophageal reflux disease | 54.61 | 52.38 | 22 | 86001 | 104224 | 79554141 |
Dysarthria | 54.57 | 52.38 | 5 | 86018 | 67617 | 79590748 |
Road traffic accident | 54.30 | 52.38 | 135 | 85888 | 43529 | 79614836 |
Sleep disorder | 54.04 | 52.38 | 209 | 85814 | 85468 | 79572897 |
Abdominal distension | 53.91 | 52.38 | 31 | 85992 | 119619 | 79538746 |
Blood alkaline phosphatase increased | 53.33 | 52.38 | 4 | 86019 | 63660 | 79594705 |
Atrial fibrillation | 53.11 | 52.38 | 82 | 85941 | 197804 | 79460561 |
None
Source | Code | Description |
---|---|---|
MeSH PA | D000893 | Anti-Inflammatory Agents |
Disease | Relation | SNOMED_ID | DOID |
---|---|---|---|
Disorder of musculoskeletal system | indication | 928000 | DOID:17 |
Cerebral edema | indication | 2032001 | |
Otitis externa | indication | 3135009 | |
Proctitis | indication | 3951002 | DOID:3127 |
Keratitis | indication | 5888003 | DOID:4677 |
Tinea pedis | indication | 6020002 | DOID:12403 |
Berylliosis | indication | 8247009 | DOID:10322 |
Psoriasis | indication | 9014002 | DOID:8893 |
Ankylosing spondylitis | indication | 9631008 | DOID:7147 |
Cyclitis | indication | 17657000 | |
Rheumatic heart disease | indication | 23685000 | |
Atopic dermatitis | indication | 24079001 | DOID:3310 |
Inflammatory bowel disease | indication | 24526004 | DOID:0050589 |
Multiple sclerosis | indication | 24700007 | DOID:2377 |
Severe adrenal insufficiency | indication | 24867002 | |
Sarcoidosis | indication | 31541009 | DOID:11335 |
Idiopathic thrombocytopenic purpura | indication | 32273002 | DOID:8924 |
Psoriasis with arthropathy | indication | 33339001 | |
Crohn's disease | indication | 34000006 | |
Tendinitis | indication | 34840004 | DOID:971 |
Erythema multiforme | indication | 36715001 | |
Contact dermatitis | indication | 40275004 | DOID:2773 |
Angioedema | indication | 41291007 | DOID:1558 |
Miliary tuberculosis | indication | 47604008 | DOID:9861 |
Humoral hypercalcemia of malignancy | indication | 47709007 | |
Articular gout | indication | 48440001 | DOID:13189 |
Seborrheic dermatitis | indication | 50563003 | DOID:8741 |
Edema of larynx | indication | 51599000 | |
Chronic ulcerative proctitis | indication | 52231000 | |
Nephrotic syndrome | indication | 52254009 | DOID:1184 |
Lichen simplex chronicus | indication | 53891004 | |
Systemic lupus erythematosus | indication | 55464009 | DOID:9074 |
Allergic rhinitis | indication | 61582004 | |
Ulcerative colitis | indication | 64766004 | DOID:8577 |
Lรถffler's syndrome | indication | 64936001 | DOID:9503 |
Iritis | indication | 65074000 | DOID:1406 |
Pemphigus | indication | 65172003 | DOID:9182 |
Granuloma annulare | indication | 65508009 | DOID:3777 |
Tenosynovitis | indication | 67801009 | DOID:970 |
Blepharoconjunctivitis | indication | 68659002 | DOID:2456 |
Rheumatoid arthritis | indication | 69896004 | DOID:7148 |
Hemorrhoids | indication | 70153002 | DOID:9746 |
Transfusion reaction due to serum protein reaction | indication | 72284000 | |
Epicondylitis | indication | 73583000 | DOID:14087 |
Acquired thrombocytopenia | indication | 74576004 | DOID:11126 |
Iridocyclitis | indication | 77971008 | |
Thyroiditis | indication | 82119001 | DOID:7166 |
Bursitis | indication | 84017003 | DOID:2965 |
Tinea corporis | indication | 84849002 | |
Autoimmune disease | indication | 85828009 | |
Corneal abrasion | indication | 85848002 | |
Infective otitis externa | indication | 86981007 | DOID:9463 |
Infection by larvae of Trichinella spiralis | indication | 88264003 | |
Acne vulgaris | indication | 88616000 | |
Congenital hypoplastic anemia | indication | 88854002 | DOID:1339 |
Pruritus ani | indication | 90446007 | |
Corneal ulcer | indication | 91514001 | DOID:8463 |
Acute lymphoid leukemia | indication | 91857003 | DOID:9952 |
Disorder of skin | indication | 95320005 | DOID:37 |
Dermatitis herpetiformis | indication | 111196000 | DOID:8505 |
Hodgkin's disease | indication | 118599009 | |
Non-Hodgkin's lymphoma | indication | 118601006 | |
Mycosis fungoides | indication | 118618005 | |
Uveitis | indication | 128473001 | DOID:13141 |
Aspiration pneumonitis | indication | 155597006 | |
Asthma | indication | 195967001 | DOID:2841 |
Discoid lupus erythematosus | indication | 200938002 | |
Plaque psoriasis | indication | 200965009 | |
Transplanted organ rejection | indication | 213148006 | |
Malignant otitis externa due to Pseudomonas aeruginosa | indication | 232230009 | |
Congenital adrenal hyperplasia | indication | 237751000 | |
Scalp psoriasis | indication | 238608008 | |
Punctate keratopathy | indication | 246936005 | |
Adrenogenital disorder | indication | 267395000 | DOID:0050811 |
Pruritus of genital organs | indication | 267802000 | |
Eruption of skin | indication | 271807003 | DOID:0050486 |
Follicular non-Hodgkin's lymphoma | indication | 308121000 | |
Infective blepharitis | indication | 312219000 | |
Bacterial keratitis | indication | 314557000 | |
Disorder of eye | indication | 371405004 | DOID:5614 |
Primary adrenocortical insufficiency | indication | 373662000 | |
Adrenal cortical hypofunction | indication | 386584007 | DOID:10493 |
Herpes zoster keratitis | indication | 397573005 | |
Rosacea | indication | 398909004 | DOID:8881 |
Tinea cruris | indication | 399029005 | |
Erythroderma | indication | 399992009 | |
Primary cutaneous T-cell lymphoma | indication | 400122007 | |
Recurrent herpes simplex labialis | indication | 402892009 | |
Juvenile rheumatoid arthritis | indication | 410795001 | |
Autoimmune hemolytic anemia | indication | 413603009 | DOID:718 |
Synovitis | indication | 416209007 | DOID:2703 |
Aphthous ulcer of mouth | indication | 426965005 | DOID:9663 |
Allergic conjunctivitis | indication | 473460002 | DOID:11204 |
Post traumatic osteoarthritis | indication | 699262001 | |
Itching of ear | indication | 699392007 | |
Inflammatory dermatosis | indication | 703938007 | |
Post-Op Ocular Inflammation | indication | ||
Staphylococcus Aureus Otitis Externa | indication | ||
Mastoidectomy Cavity Infections | indication | ||
Systemic Dermatomyositis | indication | ||
Diagnostic Test for Cushing's Syndrome | indication | ||
Gingival Disorders | indication | ||
Synovitis due to Osteoarthritis | indication | ||
Minor Bacterial Skin Infections | indication | ||
Erythroblastic Anemia | indication | ||
Transfusion Reaction Urticaria | indication | ||
Superficial Ocular Infection | indication | ||
Pericarditis | off-label use | 3238004 | DOID:1787 |
Chronic obstructive lung disease | off-label use | 13645005 | DOID:3083 |
West syndrome | off-label use | 28055006 | |
Orthostatic hypotension | off-label use | 28651003 | |
Vasculitis | off-label use | 31996006 | DOID:865 |
Bronchitis | off-label use | 32398004 | DOID:6132 |
Chronic purulent otitis media | off-label use | 38394007 | DOID:14247 |
Eczema | off-label use | 43116000 | |
Respiratory distress syndrome in the newborn | off-label use | 46775006 | |
Nasal polyp | off-label use | 52756005 | |
Rheumatic fever | off-label use | 58718002 | DOID:1586 |
Pseudogout | off-label use | 60782007 | |
Polymyalgia rheumatica | off-label use | 65323003 | DOID:853 |
Adrenoleukodystrophy | off-label use | 65389002 | DOID:10588 |
Chronic hepatitis | off-label use | 76783007 | DOID:2237 |
Pemphigoid | off-label use | 86142006 | |
Hepatic necrosis | off-label use | 87248009 | |
Multiple myeloma | off-label use | 109989006 | DOID:9538 |
Polyarteritis nodosa | off-label use | 155441006 | DOID:9810 |
Pityriasis simplex | off-label use | 200767005 | |
Celiac disease | off-label use | 396331005 | DOID:10608 |
Carditis | off-label use | 399617002 | |
Allergic otitis externa | off-label use | 405821001 | |
Giant cell arteritis | off-label use | 414341000 | DOID:13375 |
Itching of skin | off-label use | 418363000 | |
Congenital Pituitary Hypoplasia | off-label use | ||
Hypercalcemia associated with Sarcoidosis | off-label use | ||
Neonatal Bronchopulmonary Dysplasia | off-label use | ||
Otitis Externa Eczema | off-label use | ||
Otitis Externa Seborrhea | off-label use | ||
Mycosis | contraindication | 3218000 | DOID:1564 |
Ocular hypertension | contraindication | 4210003 | DOID:9282 |
Herpes simplex keratitis | contraindication | 9389005 | |
Bacterial septicemia | contraindication | 10001005 | DOID:0040085 |
Inactive tuberculosis | contraindication | 11999007 | |
Peptic ulcer | contraindication | 13200003 | DOID:750 |
Hypercholesterolemia | contraindication | 13644009 | |
Measles | contraindication | 14189004 | DOID:8622 |
Esophagitis | contraindication | 16761005 | DOID:11963 |
Disease caused by parasite | contraindication | 17322007 | |
Mood swings | contraindication | 18963009 | |
Infection of skin AND/OR subcutaneous tissue | contraindication | 19824006 | |
Cirrhosis of liver | contraindication | 19943007 | DOID:5082 |
Herpes zoster auricularis | contraindication | 21954000 | DOID:9210 |
Glaucoma | contraindication | 23986001 | DOID:1686 |
Abscess of intestine | contraindication | 24557004 | |
Acute tuberculosis | contraindication | 25629007 | |
Shock | contraindication | 27942005 | |
Herpes simplex dendritic keratitis | contraindication | 29943008 | |
Fungal infection of eye | contraindication | 31194008 | |
Bullous myringitis | contraindication | 33528003 | DOID:13791 |
Viral disease | contraindication | 34014006 | DOID:934 |
Severe myopia | contraindication | 34187009 | |
Hyperthyroidism | contraindication | 34486009 | DOID:7998 |
Gastrointestinal fistula | contraindication | 37831005 | |
Hypertensive disorder | contraindication | 38341003 | DOID:10763 |
Infectious disease | contraindication | 40733004 | |
Hypothyroidism | contraindication | 40930008 | DOID:1459 |
Hypokalemia | contraindication | 43339004 | |
Body fluid retention | contraindication | 43498006 | |
Hypercortisolism | contraindication | 47270006 | |
Chronic heart failure | contraindication | 48447003 | |
Tuberculosis of eye | contraindication | 49107007 | |
Duodenal ulcer disease | contraindication | 51868009 | DOID:1724 |
Perforation of tympanic membrane | contraindication | 60442001 | |
Osteoporosis | contraindication | 64859006 | DOID:11476 |
Psychotic disorder | contraindication | 69322001 | |
Diabetes mellitus | contraindication | 73211009 | DOID:9351 |
Hypopituitarism | contraindication | 74728003 | DOID:9406 |
Third degree burn injury | contraindication | 80247002 | |
Hyperglycemia | contraindication | 80394007 | DOID:4195 |
Decreased respiratory function | contraindication | 80954004 | |
Open-angle glaucoma | contraindication | 84494001 | DOID:1067 |
Epilepsy | contraindication | 84757009 | DOID:1826 |
Krukenberg spindle | contraindication | 85430004 | |
Bacterial infectious disease | contraindication | 87628006 | |
Herpes simplex | contraindication | 88594005 | DOID:8566 |
Kidney disease | contraindication | 90708001 | DOID:557 |
Myasthenia gravis | contraindication | 91637004 | DOID:437 |
Disorder of mucous membrane | contraindication | 95351003 | |
Bilateral cataracts | contraindication | 95722004 | |
Hypoalbuminemia | contraindication | 119247004 | |
Open wound | contraindication | 125643001 | |
Eye infection | contraindication | 128351009 | |
Seizure disorder | contraindication | 128613002 | |
Bacterial infection of eye | contraindication | 128984004 | |
Disorder of muscle | contraindication | 129565002 | DOID:423 |
Tuberculosis of ear | contraindication | 186269001 | |
Ophthalmic herpes simplex | contraindication | 186542001 | |
Heart block | contraindication | 233916004 | |
Anastomosis of intestine | contraindication | 235407009 | |
Disease of liver | contraindication | 235856003 | DOID:409 |
Condyloma acuminatum | contraindication | 240542006 | DOID:11168 |
Telangiectasia disorder | contraindication | 247479008 | |
Diverticulitis of gastrointestinal tract | contraindication | 271366000 | |
Peripheral edema | contraindication | 271809000 | |
Injury of eye region | contraindication | 282752000 | |
Varicella-zoster virus infection | contraindication | 309465005 | |
Severe depression | contraindication | 310497006 | |
Viral eye infection | contraindication | 312132001 | |
Viral ear infection | contraindication | 312137007 | |
Fungal ear infection | contraindication | 312148000 | |
Infective otitis media | contraindication | 312218008 | |
Skin irritation | contraindication | 367466007 | |
Vaccinia keratitis | contraindication | 397552005 | |
Gastric ulcer | contraindication | 397825006 | DOID:10808 |
Atrophoderma | contraindication | 399979006 | |
Peripheral vascular disease | contraindication | 400047006 | |
Traumatic rupture of tendon | contraindication | 415749005 | |
Blister | contraindication | 417237009 | |
Denuded skin | contraindication | 418242004 | |
Exposure to varicella | contraindication | 444453009 | |
Psychiatric Disturbance | contraindication | ||
Protozoal Infection | contraindication |
None
None
Dissociation level | Dissociation constant | Type (acidic/basic) |
---|---|---|
pKa1 | 13.63 | acidic |
None
None
Target | Class | Pharos | UniProt | Action | Type | Activity value (-log[M]) | Mechanism action | Bioact source | MoA source |
---|---|---|---|---|---|---|---|---|---|
Glucocorticoid receptor | Nuclear hormone receptor | AGONIST | Kd | 6.02 | WOMBAT-PK | KEGG DRUG | |||
Annexin A1 | Cytosolic other | WOMBAT-PK | |||||||
Corticosteroid-binding globulin | Secreted | Ki | 6.89 | CHEMBL | |||||
Potassium voltage-gated channel subfamily A member 1 | Ion channel | EC50 | 4.48 | CHEMBL | |||||
Sex hormone-binding globulin | Secreted | Kd | 6.43 | CHEMBL | |||||
Multidrug and toxin extrusion protein 1 | Transporter | IC50 | 4.67 | CHEMBL | |||||
Protein farnesyltransferase | Enzyme | IC50 | 4.85 | CHEMBL |
ID | Source |
---|---|
4017937 | VUID |
N0000146287 | NUI |
D00973 | KEGG_DRUG |
21655 | RXNORM |
4017936 | VANDF |
C0056391 | UMLSCUI |
CHEBI:3897 | CHEBI |
CHEMBL1650 | ChEMBL_ID |
D003348 | MESH_DESCRIPTOR_UI |
DB01380 | DRUGBANK_ID |
5745 | PUBCHEM_CID |
883WKN7W8X | UNII |
4508 | MMSL |
51 | MMSL |
92 | MMSL |
002146 | NDDF |
127382005 | SNOMEDCT_US |
53-06-5 | SECONDARY_CAS_RN |
Product | Category | Ingredients | NDC | Form | Quantity | Route | Marketing | Label |
---|---|---|---|---|---|---|---|---|
Cortisone Acetate | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0143-1202 | TABLET | 25 mg | ORAL | ANDA | 14 sections |
Cortisone Acetate | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0143-9700 | TABLET | 25 mg | ORAL | ANDA | 14 sections |
Cortisone Acetate | HUMAN PRESCRIPTION DRUG LABEL | 1 | 62135-173 | TABLET | 25 mg | ORAL | ANDA | 10 sections |