Stem definition | Drug id | CAS RN |
---|---|---|
anti-inflammatory, anilinonicotinic acid derivatives | 705 | 17737-65-4 |
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Source | Code | Description |
---|---|---|
MeSH PA | D000700 | Analgesics |
MeSH PA | D018712 | Analgesics, Non-Narcotic |
MeSH PA | D000893 | Anti-Inflammatory Agents |
MeSH PA | D000894 | Anti-Inflammatory Agents, Non-Steroidal |
MeSH PA | D018501 | Antirheumatic Agents |
MeSH PA | D018373 | Peripheral Nervous System Agents |
MeSH PA | D018689 | Sensory System Agents |
CHEBI has role | CHEBI:35475 | non-steroidal anti-inflammatory agent |
CHEBI has role | CHEBI:35493 | anti-pyretic |
CHEBI has role | CHEBI:35544 | cyclooxygenase inhibitors |
CHEBI has role | CHEBI:35620 | vasodilator agents |
CHEBI has role | CHEBI:35856 | lipoxygenase inhibitors |
CHEBI has role | CHEBI:50427 | platelet aggregation inhibitors |
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Dissociation level | Dissociation constant | Type (acidic/basic) |
---|---|---|
pKa1 | 1.96 | acidic |
pKa2 | 5.45 | Basic |
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Target | Class | Pharos | UniProt | Action | Type | Activity value (-log[M]) | Mechanism action | Bioact source | MoA source |
---|---|---|---|---|---|---|---|---|---|
Dihydroorotate dehydrogenase (quinone), mitochondrial | Enzyme | IC50 | 4.89 | CHEMBL |
ID | Source |
---|---|
N0000167333 | NUI |
D03555 | KEGG_DRUG |
2601 | RXNORM |
C0009018 | UMLSCUI |
CHEBI:76200 | CHEBI |
6J3 | PDB_CHEM_ID |
CHEMBL1332971 | ChEMBL_ID |
DB09218 | DRUGBANK_ID |
D003002 | MESH_DESCRIPTOR_UI |
28718 | PUBCHEM_CID |
2718 | INN_ID |
V7DXN0M42R | UNII |
004344 | NDDF |
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