choline alfoscerate 🐢 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
627 28319-77-9

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • choline alfoscerate
  • L-alpha-Glycerophosphocholine
  • alpha-Glycerophosphorylcholine
  • alpha-Glycerylphosphorylcholine
  • Molecular weight: 257.22
  • Formula: C8H20NO6P
  • CLOGP: -12.60
  • LIPINSKI: 0
  • HAC: 7
  • HDO: 2
  • TPSA: 99.05
  • ALOGS: -1.54
  • ROTB: 8

  • Status: OFP

  • Legend:
    OFP - off patent
    OFM - off market
    ONP - on patent

Drug dosage:

None

ADMET properties:

None

Approvals:

None

FDA Adverse Event Reporting System (Female)

MedDRA adverse event termLikelihood ratioLikelihood ratio thresholdPatients taking drug having adverse eventPatients taking drug not having adverse eventPatients not taking drug having adverse eventPatients not taking drug not having adverse event
Disorganised speech 50.72 48.95 7 91 1088 56290881

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

None

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

SourceCodeDescription
ATC N07AX02 NERVOUS SYSTEM
OTHER NERVOUS SYSTEM DRUGS
PARASYMPATHOMIMETICS
Other parasympathomimetics
MeSH PA D000963 Antimetabolites
MeSH PA D002491 Central Nervous System Agents
MeSH PA D005765 Gastrointestinal Agents
MeSH PA D000960 Hypolipidemic Agents
MeSH PA D057847 Lipid Regulating Agents
MeSH PA D008082 Lipotropic Agents
MeSH PA D018697 Nootropic Agents
CHEBI has role CHEBI:25512 neurotransmitters
CHEBI has role CHEBI:33284 nutrients
CHEBI has role CHEBI:50904 alergeno
CHEBI has role CHEBI:75771 Mus musculus metabolites
CHEBI has role CHEBI:75772 S. cerevisiae metabolites
CHEBI has role CHEBI:76924 plant metabolites
CHEBI has role CHEBI:76971 Escherichia coli metabolites
CHEBI has role CHEBI:77746 Homo sapiens metabolite
CHEBI has role CHEBI:83056 Daphnia magna metabolites
CHEBI has role CHEBI:50370 parasympatholytics
CHEBI has role CHEBI:63726 neuroprotective agents

Drug Use | Suggest Off label Use Form| |View source of the data|

None




🐢 Veterinary Drug Use

None

🐢 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

Dissociation levelDissociation constantType (acidic/basic)
pKa1 1.2 acidic
pKa2 13.63 acidic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

IDSource
N0000168626 NUI
D07349 KEGG_DRUG
2449 RXNORM
4017699 VANDF
C0017889 UMLSCUI
CHEBI:16870 CHEBI
CHEBI:15354 CHEBI
CH5 PDB_CHEM_ID
CHEMBL1567463 ChEMBL_ID
DB04660 DRUGBANK_ID
657272 PUBCHEM_CID
5203 INN_ID
60M22SGW66 UNII
DB00122 DRUGBANK_ID
4436 MMSL
4875 MMSL
d03159 MMSL
002058 NDDF
006975 NDDF
111156002 SNOMEDCT_US
65123005 SNOMEDCT_US
C0008405 UMLSCUI
D002794 MESH_DESCRIPTOR_UI
305 PUBCHEM_CID

Pharmaceutical products:

None