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choline alfoscerate 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | PK/Tox | Related Drugs | BioActivity |
| Stem definition | Drug id | CAS RN |
|---|---|---|
| 627 | 28319-77-9 |
Description:
| Molecule | Description |
|---|---|
|
Synonyms:
|
Legend: OFP - off patent OFM - off market ONP - on patent |
Drug dosage:
None
ADMET properties:
None
Predicted pharmacokinetic/toxicological properties (PK-AZ):
| Property | Description | Value | Unit | Confidence | Similarity |
|---|---|---|---|---|---|
| kinase-safety-class | ACVR2A,ACVR2B,ACVRL1,AKT2,AKT3,AURKA,AXL,BRAF,BTK,CAMK2B,CAMK2D,CDK4,CDK5,CDK9,DDR1,DYRK1B,EGFR,EIF2AK3,EPHB4,ERBB2,FLT3,GRK2,GSK3B,IGF1R,IKBKB,ITK,JAK2,JAK3,KDR,MAP2K6,MAP3K14,MAP3K21,MAP3K7,MAPK10,MAPK7,MAPK9,MAPKAPK2,MTOR,NTRK2,PDK1,PDK2,PDK4,PDPK1,PIK3CB,PIK3CD,PIK3CG,PIM2,PLK1,PRKCD,PRKDC,SIK2,SIK3,STK33,SYK,TEK,TGFBR1,TTK,ZAP70 | 58 | |||
| kinase-selectivity-class | AURKA,AXL,BRAF,CAMK2D,CDK1,CDK2,CDK4,CDK6,CDK9,CHUK,EPHB4,ERBB2,GRK2,IRAK1,IRAK3,MAP2K6,MAP3K21,MAPK7,PIK3CD,PRKDC,STK33,SYK,TEK,ZAP70 | 24 | |||
| pfas-class | PFAS structural alert (1 = True, 0 = False) | 0 |
Approvals:
None
FDA Adverse Event Reporting System (Female)
None
FDA Adverse Event Reporting System (Male)
None
FDA Adverse Event Reporting System (Geriatric)
None
FDA Adverse Event Reporting System (Pediatric)
None
Pharmacologic Action:
| Source | Code | Description |
|---|---|---|
| ATC | N07AX02 | NERVOUS SYSTEM OTHER NERVOUS SYSTEM DRUGS PARASYMPATHOMIMETICS Other parasympathomimetics |
| MeSH PA | D000960 | Hypolipidemic Agents |
| MeSH PA | D000963 | Antimetabolites |
| MeSH PA | D005765 | Gastrointestinal Agents |
| MeSH PA | D008082 | Lipotropic Agents |
| MeSH PA | D018697 | Nootropic Agents |
| MeSH PA | D057847 | Lipid Regulating Agents |
| CHEBI has role | CHEBI:25512 | neurotransmitter |
| CHEBI has role | CHEBI:33284 | nutrient |
| CHEBI has role | CHEBI:50904 | allergen |
| CHEBI has role | CHEBI:75771 | mouse metabolite |
| CHEBI has role | CHEBI:75772 | <em>Saccharomyces cerevisiae </em> metabolite |
| CHEBI has role | CHEBI:76924 | plant metabolite |
| CHEBI has role | CHEBI:76971 | <em>Escherichia coli</em> metabolite |
| CHEBI has role | CHEBI:77746 | human metabolite |
| CHEBI has role | CHEBI:83056 | <em>Daphnia magna</em> metabolite |
| CHEBI has role | CHEBI:35526 | hypoglycemic agent |
| CHEBI has role | CHEBI:50370 | parasympatholytic |
| CHEBI has role | CHEBI:63726 | neuroprotective agent |
Related Drugs by ATC class:
N07AX Other parasympathomimetics 2 drugs
Drug Use | Suggest Off label Use Form| |View source of the data|
None
🐶 Veterinary Drug Use
None
🐶 Veterinary products
None
Acid dissociation constants calculated using MoKa v3.0.0
| Dissociation level | Dissociation constant | Type (acidic/basic) |
|---|---|---|
| pKa1 | 1.2 | acidic |
| pKa2 | 13.63 | acidic |
Orange Book patent data (new drug applications)
None
Orange Book exclusivity data (new drug applications)
None
Bioactivity Summary:
None
External reference:
| ID | Source |
|---|---|
| N0000168626 | NUI |
| D07349 | KEGG_DRUG |
| 2449 | RXNORM |
| C0017889 | UMLSCUI |
| CHEBI:16870 | CHEBI |
| CHEMBL6067974 | ChEMBL_ID |
| DB04660 | DRUGBANK_ID |
| 657272 | PUBCHEM_CID |
| 5203 | INN_ID |
| 60M22SGW66 | UNII |
| 4436 | MMSL |
| 4875 | MMSL |
| d03159 | MMSL |
| 002058 | NDDF |
| 006975 | NDDF |
| 111156002 | SNOMEDCT_US |
| 65123005 | SNOMEDCT_US |
| C0008405 | UMLSCUI |
| CH5 | PDB_CHEM_ID |
| DB00122 | DRUGBANK_ID |
| 305 | PUBCHEM_CID |
| 4017699 | VANDF |
| D002794 | MESH_DESCRIPTOR_UI |
| CHEBI:15354 | CHEBI |
Pharmaceutical products:
None