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zilpaterol 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | PK/Tox | Related Drugs | BioActivity |
| Stem definition | Drug id | CAS RN |
|---|---|---|
| bronchodilators, phenethylamine derivatives | 5645 | 119520-05-7 |
Description:
| Molecule | Description |
|---|---|
|
Synonyms:
|
Is an adrenergic drug currently licensed in Mexico and South Africa as feed additive for cattle close to consignment
|
Drug dosage:
None
ADMET properties:
None
Predicted pharmacokinetic/toxicological properties (PK-AZ):
| Property | Description | Value | Unit | Confidence | Similarity |
|---|---|---|---|---|---|
| pfas-class | PFAS structural alert (1 = True, 0 = False) | 0 |
Approvals:
| Date | Agency | Company | Orphan |
|---|---|---|---|
| None | FDA |
FDA Adverse Event Reporting System (Female)
None
FDA Adverse Event Reporting System (Male)
None
FDA Adverse Event Reporting System (Geriatric)
None
FDA Adverse Event Reporting System (Pediatric)
None
Pharmacologic Action:
None
Drug Use | Suggest Off label Use Form| |View source of the data|
None
🐶 Veterinary Drug Use
| Species | Use | Relation |
|---|---|---|
| Cattle | To increase rate of weight gain | Indication |
| Cattle | To improve feed efficiency | Indication |
| Cattle | To increase carcass leanness | Indication |
🐶 Veterinary products
| Product | Applicant | Ingredients |
|---|---|---|
| Zilmax | Intervet Inc. | 1 |
| Zilmax and Rumensin and Tylan | Intervet Inc. | 3 |
| Zilmax plus Rumensin | Intervet Inc. | 2 |
| Zilmax and Rumensin and Tylan and MGA | Intervet Inc. | 4 |
| Zilmax/Rumensin/MGA | Intervet Inc. | 3 |
| Zilmax plus MGA | Intervet Inc. | 2 |
| Heifermax 500/Zilmax/Rumensin | Elanco US Inc. | 3 |
| Heifermax 500/Zilmax/Rumensin/Tylan | Elanco US Inc. | 4 |
| Heifermax 500 plus Zilmax | Elanco US Inc. | 2 |
| Zilmax/Rumensin/Tylovet 100/MGA | Huvepharma EOOD | 4 |
| Zilmax/Rumensin/Tylovet 100 | Huvepharma EOOD | 3 |
Acid dissociation constants calculated using MoKa v3.0.0
None
Orange Book patent data (new drug applications)
None
Orange Book exclusivity data (new drug applications)
None
Bioactivity Summary:
| Target | Class | Pharos | UniProt | Action | Type | Activity value (-log[M]) | Mechanism action | Bioact source | MoA source |
|---|---|---|---|---|---|---|---|---|---|
| Beta-2 adrenergic receptor | GPCR | Ki | 6.50 | CHEMBL | |||||
| Mu-type opioid receptor | GPCR | Ki | 4.89 | CHEMBL |
External reference:
| ID | Source |
|---|---|
| CHEBI:180945 | CHEBI |
| CHEMBL2218907 | ChEMBL_ID |
| C475840 | MESH_SUPPLEMENTAL_RECORD_UI |
| DB11479 | DRUGBANK_ID |
| C1259819 | UMLSCUI |
| CHEMBL513390 | ChEMBL_ID |
| 6349 | INN_ID |
| 119520-06-8 | SECONDARY_CAS_RN |
| KEGG_DRUG | |
| 3086576 | PUBCHEM_CID |
| S384A1Y12J | UNII |
| 1727537 | RXNORM |
| C058948 | MESH_SUPPLEMENTAL_RECORD_UI |
| S384A1Y12J | INXIGHT DRUGS |
Pharmaceutical products:
None