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sulfomyxin 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | PK/Tox | Related Drugs | BioActivity |
| Stem definition | Drug id | CAS RN |
|---|---|---|
| 5623 | 1405-52-3 |
Description:
| Molecule | Description |
|---|---|
|
Synonyms:
|
|
Drug dosage:
None
ADMET properties:
None
Predicted pharmacokinetic/toxicological properties (PK-AZ):
| Property | Description | Value | Unit | Confidence | Similarity |
|---|---|---|---|---|---|
| azlogd74 | LogD at pH 7.4 | -0.277 | High | 0.93 | |
| caco2-efflux | Caco-2 efflux ratio (BA/AB) | 1.641 | High | 0.93 | |
| caco2-intrinsic-papp | Caco-2 intrinsic apparent permeability | 0.364 | 10^-6 cm/s | High | 0.93 |
| dh-clint | Dog hepatocyte intrinsic clearance | 1.714 | uL/min/10^6 cells | High | 0.93 |
| dppb | Dog plasma protein binding (% unbound) | 22.950 | % | High | 0.93 |
| fcs-ppb | Fetal calf serum protein binding (% unbound) | 25.880 | % | High | 0.93 |
| herg | hERG pIC50 | 4.838 | pIC50 | High | 0.93 |
| hh-clint | Human hepatocyte intrinsic clearance | 2.018 | uL/min/10^6 cells | High | 0.93 |
| hlm-clint | Human liver microsomal intrinsic clearance | 4.699 | uL/min/mg protein | High | 0.93 |
| hppb | Human plasma protein binding (% unbound) | 17.120 | % | High | 0.93 |
| mdck-mdr1-efflux | MDCK-MDR1 efflux ratio | 3.342 | High | 0.93 | |
| mh-clint | Mouse hepatocyte intrinsic clearance | 3.436 | High | 0.93 | |
| mppb | Mouse plasma protein binding (% unbound) | 10.410 | High | 0.93 | |
| nih-mdck-mdr1-efflux | NIH MDCK-MDR1 efflux ratio | 2.698 | High | 0.93 | |
| pfas-class | PFAS structural alert (1 = True, 0 = False) | 0 | |||
| pppb | Pig plasma protein binding (% unbound) | 31.170 | % | High | 0.93 |
| rh-clint | Rat hepatocyte intrinsic clearance | 1.442 | uL/min/10^6 cells | High | 0.93 |
| rh-fuinc | Rat hepatocyte fraction unbound in incubation | 49.310 | % | High | 0.93 |
| rppb | Rat plasma protein binding (% unbound) | 21.090 | % | High | 0.93 |
| solubility-dd | Solubility at pH 7.4 in DMSO | 839.460 | uM | High | 0.93 |
Approvals:
| Date | Agency | Company | Orphan |
|---|---|---|---|
| None | FDA |
FDA Adverse Event Reporting System (Female)
None
FDA Adverse Event Reporting System (Male)
None
FDA Adverse Event Reporting System (Geriatric)
None
FDA Adverse Event Reporting System (Pediatric)
None
Pharmacologic Action:
None
Drug Use | Suggest Off label Use Form| |View source of the data|
None
🐶 Veterinary Drug Use
| Species | Use | Relation |
|---|---|---|
| Chickens | Disease caused or complicated by Escherichia coli | Indication |
| Chickens | Colibacillosis | Indication |
| Chickens | Complicated chronic respiratory disease | Indication |
| Turkeys | Disease caused or complicated by Escherichia coli | Indication |
| Turkeys | Colibacillosis | Indication |
| Turkeys | Complicated chronic respiratory disease | Indication |
🐶 Veterinary products
| Product | Applicant | Ingredients |
|---|---|---|
| Dynamyxin Injectable | Zoetis Inc. | 1 |
Acid dissociation constants calculated using MoKa v3.0.0
None
Orange Book patent data (new drug applications)
None
Orange Book exclusivity data (new drug applications)
None
Bioactivity Summary:
None
External reference:
| ID | Source |
|---|---|
| CHEBI:757733 | CHEBI |
| CHEMBL4594215 | ChEMBL_ID |
| 96010001 | SNOMEDCT_US |
| C0521887 | UMLSCUI |
| 1933 | INN_ID |
| D05959 | KEGG_DRUG |
| 3083710 | PUBCHEM_CID |
| 094M0E38I6 | UNII |
Pharmaceutical products:
None