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| Stem definition | Drug id | CAS RN |
|---|---|---|
| antiviral, monoclonal antibodies | 5501 | 2444308-95-4 |
| Molecule | Description |
|---|---|
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Synonyms:
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Regdanvimab is a recombinant human IgG1 monoclonal antibody that binds to the receptor binding domain (RBD) of the spike(s) protein of SARS-CoV-2 consequently blocking cellular entry and SARS-CoV-2 infection.
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| Date | Agency | Company | Orphan |
|---|---|---|---|
| Nov. 12, 2021 | EMA | CELLTRION HEALTHCARE HUNGARY KFT. |
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| Source | Code | Description |
|---|---|---|
| ATC | J06BD06 | ANTIINFECTIVES FOR SYSTEMIC USE IMMUNE SERA AND IMMUNOGLOBULINS IMMUNOGLOBULINS Antiviral monoclonal antibodies |
| CHEBI has role | CHEBI:22587 | antiviral agent |
| CHEBI has role | CHEBI:149553 | anticoronaviral agent |
| Disease | Relation | SNOMED_ID | DOID |
|---|---|---|---|
| COVID-19 | indication | 840539006 |
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| Target | Class | Pharos | UniProt | Action | Type | Activity value (-log[M]) | Mechanism action | Bioact source | MoA source |
|---|---|---|---|---|---|---|---|---|---|
| Spike glycoprotein | Glycoprotein | BINDING AGENT | Kd | 9.57 | SCIENTIFIC LITERATURE | DRUG LABEL |
| ID | Source |
|---|---|
| CHEBI:758345 | CHEBI |
| CHEMBL4650462 | ChEMBL_ID |
| C000716788 | MESH_SUPPLEMENTAL_RECORD_UI |
| 11332 | IUPHAR_LIGAND_ID |
| DB16405 | DRUGBANK_ID |
| 40395111000001102 | SNOMEDCT_US |
| C5432268 | UMLSCUI |
| D12241 | KEGG_DRUG |
| 11883 | INN_ID |
| 018944 | NDDF |
| I0BGE6P6I6 | UNII |
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