cefcapene pivoxil 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
antibiotics, cefalosporanic acid derivatives 532 105889-45-0

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • cefcapene pivoxil
  • cefcamate pivoxil
  • cefcapene pivoxil hydrochloride
  • cefcapene pivoxil HCl
  • Molecular weight: 567.63
  • Formula: C23H29N5O8S2
  • CLOGP: 1.01
  • LIPINSKI: 2
  • HAC: 13
  • HDO: 3
  • TPSA: 193.24
  • ALOGS: -4.79
  • ROTB: 13

Drug dosage:

None

ADMET properties:

None

Approvals:

None

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

MedDRA adverse event termLikelihood ratioLikelihood ratio thresholdPatients taking drug having adverse eventPatients taking drug not having adverse eventPatients not taking drug having adverse eventPatients not taking drug not having adverse event
Nerve degeneration 72.78 40.74 11 905 197 34955818
Renal neoplasm 52.68 40.74 11 905 1286 34954729
Abdominal rigidity 52.18 40.74 11 905 1346 34954669
Renal mass 49.06 40.74 11 905 1793 34954222
Bone density decreased 48.33 40.74 11 905 1918 34954097

FDA Adverse Event Reporting System (Geriatric)

MedDRA adverse event termLikelihood ratioLikelihood ratio thresholdPatients taking drug having adverse eventPatients taking drug not having adverse eventPatients not taking drug having adverse eventPatients not taking drug not having adverse event
Nerve degeneration 74.36 34.09 11 1281 280 79742816
Renal neoplasm 53.14 34.09 11 1281 1997 79741099
Abdominal rigidity 48.42 34.09 11 1281 3077 79740019
Renal mass 47.56 34.09 11 1281 3329 79739767
Metastasis 39.67 34.09 11 1281 6869 79736227
Middle insomnia 34.28 34.09 12 1280 16057 79727039

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

SourceCodeDescription
CHEBI has role CHEBI:36047 antibacterial drugs

Drug Use | Suggest Off label Use Form| |View source of the data|

None




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

Dissociation levelDissociation constantType (acidic/basic)
pKa1 3.58 Basic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

IDSource
C3273882 UMLSCUI
CHEBI:131729 CHEBI
C425944 MESH_SUPPLEMENTAL_RECORD_UI
147816-23-7 SECONDARY_CAS_RN
8I8MJ56XFQ UNII
5282438 PUBCHEM_CID
C2699134 UMLSCUI
DB13461 DRUGBANK_ID
7006 INN_ID
6436055 PUBCHEM_CID

Pharmaceutical products:

None