zabofloxacin 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
antibacterials, nalidixic acid derivatives 5249 219680-11-2

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • DW-224a
  • zabofloxacin
  • zabolante
  • zabofloxacin hydrochloride
  • zabofloxacin HCl
  • DW-224
  • DW-224aa
  • PB-101
Zabofloxacin is a fluoroquinolone antibiotic with enhanced in-vitro activity against Streptococcus pneumoniae, including strains resistant to other antibiotics. The spectrum of activity of Zabofloxacin includes those bacterial strains that are responsible for most community-acquired respiratory infections.
  • Molecular weight: 401.40
  • Formula: C19H20FN5O4
  • CLOGP: -1.12
  • LIPINSKI: 0
  • HAC: 9
  • HDO: 2
  • TPSA: 107.36
  • ALOGS: -3.31
  • ROTB: 4

Drug dosage:

None

ADMET properties:

None

Approvals:

DateAgencyCompanyOrphan
March 20, 2015 Korean Food and Drug Administration (KFDA) Dong Wha Pharmaceuticals

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

None

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

None

Drug Use | Suggest Off label Use Form| |View source of the data|

DiseaseRelationSNOMED_IDDOID
Acute infective exacerbation of chronic obstructive airways disease indication 285381006




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

Dissociation levelDissociation constantType (acidic/basic)
pKa1 6.27 acidic
pKa2 8.46 Basic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

IDSource
LV66BA6V2G UNII
623574-00-5 SECONDARY_CAS_RN
C2826065 UMLSCUI
CHEMBL2107811 ChEMBL_ID
54556623 PUBCHEM_CID
DB12479 DRUGBANK_ID
CHEMBL232122 ChEMBL_ID
8594 INN_ID
10873 IUPHAR_LIGAND_ID
C480202 MESH_SUPPLEMENTAL_RECORD_UI

Pharmaceutical products:

None