ferrous bisglycinate 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | PK/Tox | Related Drugs | BioActivity |

Stem definitionDrug idCAS RN
5187 20150-34-9

Description:

MoleculeDescription

Synonyms:

  • ferrous bisglycinate
  • ferrous glycinate
  • iron bisglycinate
  • iron glycinate
an iron fortificant in bread for iron-deficient school children
  • Molecular weight: 203.96
  • Formula: C4H8FeN2O4
  • CLOGP:
  • LIPINSKI: None
  • HAC: None
  • HDO: None
  • TPSA: 85.82
  • ALOGS:
  • ROTB: None

Drug dosage:

None

ADMET properties:

None

Predicted pharmacokinetic/toxicological properties (PK-AZ):

None

Approvals:

DateAgencyCompanyOrphan
None FDA

FDA Adverse Event Reporting System (Female)

MedDRA adverse event termLikelihood ratioLikelihood ratio thresholdPatients taking drug having adverse eventPatients taking drug not having adverse eventPatients not taking drug having adverse eventPatients not taking drug not having adverse event
Product dose omission issue 112.83 11.99 334 39832 291353 90296928
Product use in unapproved indication 112.24 11.99 10 40156 336226 90252055
Systemic lupus erythematosus 110.11 11.99 15 40151 361881 90226400
Diarrhoea 108.06 11.99 748 39418 938442 89649839
Glossodynia 103.64 11.99 11 40155 321768 90266513
Pericarditis 102.30 11.99 4 40162 270147 90318134
Maternal exposure during pregnancy 100.39 11.99 19 40147 360044 90228237
Off label use 99.66 11.99 213 39953 1102039 89486242
Treatment failure 98.89 11.99 10 40156 303918 90284363
Infusion related reaction 93.46 11.99 34 40132 416746 90171535
Wound 88.81 11.99 14 40152 302966 90285315
Fall 87.24 11.99 433 39733 481377 90106904
Product use issue 86.63 11.99 20 40146 329899 90258382
Drug intolerance 85.43 11.99 46 40120 447545 90140736
Helicobacter infection 83.76 11.99 4 40162 226846 90361435
Unevaluable event 78.96 11.99 109 40057 54739 90533542
Device expulsion 75.67 11.99 92 40074 40794 90547487
Folliculitis 74.18 11.99 4 40162 204349 90383932
Fatigue 72.22 11.99 804 39362 1153219 89435062
Lower respiratory tract infection 62.29 11.99 17 40149 250642 90337639
Hepatic enzyme increased 61.91 11.99 42 40124 360694 90227587
Full blood count decreased 60.20 11.99 70 40096 29619 90558662
Deep vein thrombosis 58.52 11.99 127 40039 91493 90496788
Type 2 diabetes mellitus 58.18 11.99 10 40156 203234 90385047
Muscle spasms 57.87 11.99 243 39923 251640 90336641
Arthropathy 57.23 11.99 47 40119 366195 90222086
Intentional product use issue 57.20 11.99 13 40153 216879 90371402
Feeling abnormal 55.76 11.99 182 39984 167053 90421228
Device dislocation 55.28 11.99 69 40097 31413 90556868
Liver injury 54.45 11.99 6 40160 170561 90417720
Nausea 54.37 11.99 739 39427 1109577 89478704
Neuropathy peripheral 53.01 11.99 157 40009 136813 90451468
Therapy cessation 51.93 11.99 72 40094 36289 90551992
Irritable bowel syndrome 51.67 11.99 14 40152 207434 90380847
Therapeutic product effect decreased 50.79 11.99 30 40136 277541 90310740
Drug hypersensitivity 49.26 11.99 81 40085 463528 90124753
Haemoglobin decreased 47.61 11.99 169 39997 161787 90426494
C-reactive protein increased 47.57 11.99 11 40155 181378 90406903
Dizziness 47.45 11.99 433 39733 588851 89999430
Drug ineffective 47.00 11.99 391 39775 1383907 89204374
General physical health deterioration 46.84 11.99 53 40113 355062 90233219
Therapeutic product effect incomplete 46.60 11.99 14 40152 193882 90394399
Toxicity to various agents 44.88 11.99 37 40129 287809 90300472
Plasma cell myeloma 41.48 11.99 69 40097 40759 90547522
Constipation 41.09 11.99 238 39928 280157 90308124
Fibromyalgia 41.09 11.99 20 40146 206249 90382032
Blister 40.72 11.99 32 40134 254966 90333315
Ill-defined disorder 39.86 11.99 16 40150 184875 90403406
Dehydration 39.61 11.99 181 39985 194266 90394015
Flatulence 39.50 11.99 68 40098 41299 90546982
Back pain 39.41 11.99 258 39908 316917 90271364
Asthenia 38.86 11.99 384 39782 533367 90054914
Impaired healing 37.89 11.99 29 40137 234170 90354111
Urinary tract infection 36.40 11.99 246 39920 305386 90282895
Pneumonia 35.85 11.99 436 39730 637623 89950658
Psoriasis 35.83 11.99 145 40021 147609 90440672
Headache 35.29 11.99 557 39609 862189 89726092
Discomfort 35.02 11.99 42 40124 274293 90313988
Joint swelling 34.75 11.99 111 40055 503189 90085092
Pulmonary embolism 34.65 11.99 132 40034 130688 90457593
Joint range of motion decreased 34.06 11.99 9 40157 135634 90452647
Prescribed overdose 32.28 11.99 3 40163 97622 90490659
Hot flush 31.92 11.99 77 40089 59411 90528870
Bursitis 30.74 11.99 10 40156 131644 90456637
Intentional overdose 30.72 11.99 3 40163 93831 90494450
Injection site pain 30.54 11.99 155 40011 173544 90414737
Injection site erythema 29.12 11.99 103 40063 98399 90489882
COVID-19 28.48 11.99 20 40146 168823 90419458
Exposure during pregnancy 27.85 11.99 39 40127 238371 90349910
Injection site haemorrhage 27.62 11.99 47 40119 28271 90560010
Pelvic pain 27.51 11.99 34 40132 15323 90572958
Influenza like illness 27.09 11.99 88 40078 80523 90507758
Wheezing 26.77 11.99 40 40126 238040 90350241
Obesity 26.49 11.99 7 40159 105500 90482781
Tremor 26.44 11.99 136 40030 153037 90435244
Rheumatoid arthritis 26.41 11.99 78 40088 362536 90225745
Dyspnoea 26.17 11.99 541 39625 880414 89707867
Asthma 25.97 11.99 42 40124 242118 90346163
Grip strength decreased 25.52 11.99 5 40161 92571 90495710
Wound infection 24.98 11.99 8 40158 106394 90481887
Hip fracture 24.80 11.99 49 40117 33028 90555253
Blood potassium decreased 24.78 11.99 61 40105 47666 90540615
Atrial fibrillation 24.73 11.99 121 40045 133490 90454791
Laboratory test abnormal 24.44 11.99 56 40110 41798 90546483
Peripheral venous disease 24.29 11.99 4 40162 83917 90504364
White blood cell count decreased 23.90 11.99 141 40025 166968 90421313
Eye swelling 23.83 11.99 45 40121 29341 90558940
Hypersensitivity 23.24 11.99 113 40053 454564 90133717
Nasal congestion 22.77 11.99 85 40081 83329 90504952
Hypervolaemia 22.75 11.99 47 40119 32710 90555571
Alopecia 22.54 11.99 128 40038 494943 90093338
Sleep disorder 22.52 11.99 33 40133 197997 90390284
Balance disorder 22.52 11.99 94 40072 96986 90491295
Cardiac failure congestive 22.46 11.99 95 40071 98599 90489682
Live birth 22.39 11.99 4 40162 79103 90509178
Blood cholesterol increased 22.38 11.99 36 40130 207976 90380305
Skin discolouration 22.33 11.99 56 40110 44259 90544022
Mobility decreased 22.05 11.99 49 40117 250685 90337596
Gastrointestinal disorder 21.90 11.99 51 40115 256636 90331645
Vaginal haemorrhage 21.87 11.99 45 40121 31226 90557055
Epilepsy 21.52 11.99 5 40161 82201 90506080
Thrombosis 21.13 11.99 76 40090 73175 90515106
Pulmonary arterial hypertension 21.11 11.99 40 40126 26147 90562134
Hypoxia 19.95 11.99 74 40092 72325 90515956
Pulmonary hypertension 19.64 11.99 52 40114 42471 90545810
Fluid retention 19.43 11.99 84 40082 88007 90500274
Multiple sclerosis relapse 19.32 11.99 59 40107 52246 90536035
Chills 19.28 11.99 112 40054 131869 90456412
Platelet count decreased 19.22 11.99 115 40051 136854 90451427
Dysgeusia 19.14 11.99 59 40107 52501 90535780
Infection 19.07 11.99 89 40077 362005 90226276
Vision blurred 18.39 11.99 97 40069 110196 90478085
Dyspnoea exertional 18.36 11.99 72 40094 72216 90516065
Overdose 18.21 11.99 26 40140 157683 90430598
Product complaint 18.19 11.99 26 40140 13474 90574807
Red blood cell sedimentation rate increased 18.04 11.99 7 40159 82588 90505693
Lung disorder 18.02 11.99 24 40142 149859 90438422
Pulmonary fibrosis 17.78 11.99 13 40153 107490 90480791
Flushing 17.72 11.99 82 40084 88409 90499872
Bone pain 17.62 11.99 64 40102 61919 90526362
Autoimmune disorder 17.61 11.99 6 40160 76738 90511543
Body height decreased 17.57 11.99 24 40142 11925 90576356
Condition aggravated 17.54 11.99 174 39992 595371 89992910
Dry skin 17.19 11.99 81 40085 87992 90500289
Adverse event 17.19 11.99 16 40150 117402 90470879
Suicide attempt 17.12 11.99 6 40160 75393 90512888
Pleural effusion 16.99 11.99 96 40070 111895 90476386
Myalgia 16.83 11.99 134 40032 174991 90413290
Swelling 16.64 11.99 113 40053 418945 90169336
Tooth disorder 16.42 11.99 40 40126 31050 90557231
Cellulitis 16.39 11.99 82 40084 91255 90497026
Illness 16.23 11.99 8 40158 81961 90506320
International normalised ratio increased 16.21 11.99 52 40114 47264 90541017
Abdominal discomfort 15.98 11.99 135 40031 477193 90111088
Hypertension 15.96 11.99 128 40038 457404 90130877
Injection site mass 15.70 11.99 32 40134 22058 90566223
Gallbladder disorder 15.66 11.99 30 40136 19773 90568508
Inflammation 15.62 11.99 35 40131 178557 90409724
Cardiac pacemaker insertion 15.53 11.99 14 40152 4393 90583888
Stomatitis 15.37 11.99 66 40100 274632 90313649
Oedema peripheral 15.19 11.99 178 39988 257737 90330544
Administration site swelling 15.12 11.99 9 40157 1490 90586791
Hospice care 15.04 11.99 20 40146 9684 90578597
Injection site bruising 14.86 11.99 54 40112 52253 90536028
Anaemia 14.80 11.99 229 39937 352573 90235708
Swelling face 14.57 11.99 73 40093 81279 90507002
Depression 14.54 11.99 200 39966 300401 90287880
Lethargy 14.53 11.99 61 40105 63078 90525203
Red blood cell count decreased 14.15 11.99 49 40117 46302 90541979
Plasma cell myeloma recurrent 14.06 11.99 13 40153 4215 90584066
Pollakiuria 13.88 11.99 39 40127 32966 90555315
Intestinal dilatation 13.82 11.99 10 40156 2300 90585981
Heavy menstrual bleeding 13.72 11.99 29 40137 20501 90567780
Hypophagia 13.70 11.99 41 40125 35896 90552385
Drug interaction 13.37 11.99 70 40096 276383 90311898
Multiple allergies 13.29 11.99 24 40142 15122 90573159
Weight decreased 13.15 11.99 239 39927 379671 90208610
Restless legs syndrome 13.05 11.99 30 40136 22440 90565841
Burning sensation 12.85 11.99 59 40107 63393 90524888
Abdominal pain 12.68 11.99 246 39920 395475 90192806
Haematocrit decreased 12.58 11.99 44 40122 41788 90546493
Complication associated with device 12.45 11.99 27 40139 19422 90568859
Drug-induced liver injury 12.42 11.99 13 40153 90305 90497976
Cough 12.38 11.99 231 39935 368731 90219550
Pain in jaw 12.35 11.99 48 40118 47937 90540344
Night sweats 12.29 11.99 24 40142 128742 90459539
Intentional product misuse 12.20 11.99 13 40153 89591 90498690
Liver disorder 12.11 11.99 22 40144 121247 90467034
Injection site reaction 12.08 11.99 76 40090 92004 90496277
Gait disturbance 12.06 11.99 172 39994 260324 90327957
Bronchitis 12.06 11.99 112 40054 152815 90435466
Pulmonary oedema 12.04 11.99 57 40109 62023 90526258

FDA Adverse Event Reporting System (Male)

MedDRA adverse event termLikelihood ratioLikelihood ratio thresholdPatients taking drug having adverse eventPatients taking drug not having adverse eventPatients not taking drug having adverse eventPatients not taking drug not having adverse event
Off label use 127.59 12.46 97 23059 638238 41959941
Product use in unapproved indication 83.53 12.46 4 23152 184452 42413727
Fatigue 69.78 12.46 439 22717 435202 42162977
Plasma cell myeloma 57.24 12.46 97 23059 47481 42550698
Diarrhoea 47.22 12.46 418 22738 460431 42137748
Asthenia 44.18 12.46 282 22874 280511 42317668
Product dose omission issue 43.09 12.46 182 22974 154183 42443996
Full blood count decreased 42.30 12.46 54 23102 20506 42577673
Fall 40.94 12.46 242 22914 234278 42363901
Laboratory test abnormal 40.58 12.46 56 23100 22922 42575257
White blood cell count decreased 37.10 12.46 138 23018 110258 42487921
Completed suicide 35.71 12.46 5 23151 96460 42501719
Drug interaction 34.06 12.46 58 23098 266941 42331238
Adverse drug reaction 29.75 12.46 64 23092 37370 42560809
Toxicity to various agents 29.00 12.46 50 23106 229086 42369093
Pneumonia 28.90 12.46 353 22803 421796 42176383
Dizziness 27.45 12.46 230 22926 249024 42349155
Drug ineffective 27.23 12.46 216 22940 629981 41968198
COVID-19 26.52 12.46 15 23141 115933 42482246
Viral infection 24.62 12.46 44 23112 22439 42575740
Psoriasis 22.77 12.46 68 23088 48536 42549643
General physical health deterioration 22.00 12.46 30 23126 151216 42446963
Intentional product use issue 21.82 12.46 6 23150 71827 42526352
Muscle spasms 21.35 12.46 98 23058 85946 42512233
Intentional product misuse 21.13 12.46 4 23152 61896 42536283
Neuropathy peripheral 20.98 12.46 110 23046 101743 42496436
Rash 20.40 12.46 235 22921 276719 42321460
Sinusitis 20.13 12.46 64 23092 47228 42550951
Influenza 19.45 12.46 76 23080 62099 42536080
Peripheral swelling 18.25 12.46 97 23059 90173 42508006
Cardiac disorder 17.97 12.46 63 23093 48869 42549310
Constipation 17.96 12.46 150 23006 162141 42436038
Dehydration 17.86 12.46 135 23021 141632 42456547
Treatment failure 17.63 12.46 6 23150 62618 42535561
Haemoglobin decreased 17.16 12.46 127 23029 132344 42465835
Interstitial lung disease 16.75 12.46 11 23145 78451 42519728
Influenza like illness 16.31 12.46 46 23110 31794 42566385
Overdose 16.21 12.46 20 23136 105244 42492935
Unevaluable event 16.08 12.46 48 23108 34240 42563939
Febrile neutropenia 15.85 12.46 50 23106 185653 42412526
Drug ineffective for unapproved indication 15.72 12.46 3 23153 46160 42552019
Multiple organ dysfunction syndrome 15.40 12.46 18 23138 97017 42501162
Mental status changes 15.27 12.46 54 23102 42061 42556118
Cytokine release syndrome 14.94 12.46 3 23153 44524 42553655
Platelet count decreased 14.75 12.46 127 23029 138454 42459725
Memory impairment 14.59 12.46 60 23096 50162 42548017
Flatulence 14.54 12.46 38 23118 25114 42573065
Small intestinal obstruction 14.51 12.46 30 23126 17031 42581148
Hepatic function abnormal 14.41 12.46 5 23151 51562 42546617
Foetal exposure during pregnancy 14.27 12.46 4 23152 47307 42550872
Feeling abnormal 14.11 12.46 75 23081 69711 42528468
Coma 13.63 12.46 6 23150 53548 42544631
Atelectasis 13.03 12.46 31 23125 19330 42578849
Cellulitis 13.01 12.46 67 23089 61518 42536661
Thrombosis 12.75 12.46 72 23084 68439 42529740
Fluid retention 12.74 12.46 42 23114 31577 42566602
Weight decreased 12.51 12.46 170 22986 207778 42390401
Hospice care 12.48 12.46 19 23137 8494 42589685

FDA Adverse Event Reporting System (Geriatric)

MedDRA adverse event termLikelihood ratioLikelihood ratio thresholdPatients taking drug having adverse eventPatients taking drug not having adverse eventPatients not taking drug having adverse eventPatients not taking drug not having adverse event
Off label use 186.37 11.12 245 49833 1499940 109039281
Product use in unapproved indication 159.91 11.12 11 50067 447366 110091855
Product dose omission issue 109.97 11.12 358 49720 321424 110217797
Fall 99.73 11.12 537 49541 602945 109936276
Treatment failure 98.47 11.12 7 50071 277227 110261994
Completed suicide 86.43 11.12 6 50072 242375 110296846
Diarrhoea 86.39 11.12 840 49238 1138665 109400556
Device expulsion 84.23 11.12 86 49992 30805 110508416
Systemic lupus erythematosus 80.84 11.12 10 50068 254328 110284893
Drug intolerance 80.22 11.12 42 50036 406470 110132751
Fatigue 77.79 11.12 866 49212 1215092 109324129
Plasma cell myeloma 72.61 11.12 114 49964 62822 110476399
Infusion related reaction 71.41 11.12 42 50036 381120 110158101
Product use issue 71.29 11.12 26 50052 311669 110227552
Dizziness 69.56 11.12 547 49531 697646 109841575
Drug abuse 67.53 11.12 3 50075 177408 110361813
Drug ineffective 67.30 11.12 409 49669 1520131 109019090
Toxicity to various agents 66.19 11.12 72 50006 480483 110058738
Asthenia 64.92 11.12 533 49545 688466 109850755
Duodenal ulcer perforation 64.52 11.12 4 50074 177696 110361525
Helicobacter infection 63.41 11.12 5 50073 181872 110357349
Deep vein thrombosis 63.27 11.12 172 49906 139715 110399506
Intentional product use issue 63.26 11.12 17 50061 247889 110291332
Glossodynia 63.10 11.12 12 50066 221992 110317229
Maternal exposure during pregnancy 60.45 11.12 20 50058 254863 110284358
Dehydration 59.07 11.12 267 49811 279244 110259977
Pericarditis 57.88 11.12 14 50064 219100 110320121
Haemoglobin decreased 57.43 11.12 244 49834 248483 110290738
Lower respiratory tract infection 56.06 11.12 20 50058 243086 110296135
Folliculitis 54.74 11.12 6 50072 167647 110371574
Therapy cessation 54.18 11.12 83 49995 44774 110494447
General physical health deterioration 52.92 11.12 69 50009 425226 110113995
COVID-19 51.85 11.12 23 50055 245037 110294184
Full blood count decreased 49.95 11.12 67 50011 32032 110507189
Therapeutic product effect incomplete 48.96 11.12 20 50058 223785 110315436
Drug hypersensitivity 48.39 11.12 82 49996 454008 110085213
Device dislocation 47.54 11.12 65 50013 31639 110507582
Unevaluable event 47.04 11.12 91 49987 59136 110480085
Hepatic enzyme increased 46.50 11.12 46 50032 320846 110218375
Feeling abnormal 45.41 11.12 182 49896 180529 110358692
Pneumonia 44.38 11.12 598 49480 876116 109663105
Irritable bowel syndrome 44.34 11.12 10 50068 164205 110375016
Nausea 43.61 11.12 793 49285 1234897 109304324
Drug interaction 43.28 11.12 102 49976 500081 110039140
Intentional overdose 42.61 11.12 5 50073 132496 110406725
C-reactive protein increased 42.24 11.12 23 50055 217896 110321325
Type 2 diabetes mellitus 41.85 11.12 14 50064 177218 110362003
Dyspnoea 40.68 11.12 715 49363 1106157 109433064
Wound 39.59 11.12 29 50049 234408 110304813
Muscle spasms 39.53 11.12 238 49840 277919 110261302
Fibromyalgia 39.50 11.12 14 50064 170895 110368326
Intentional product misuse 38.15 11.12 7 50071 132897 110406324
Liver injury 37.09 11.12 11 50067 150402 110388819
Arthropathy 36.41 11.12 46 50032 287476 110251745
Hypervolaemia 35.68 11.12 73 50005 49387 110489834
Joint swelling 34.67 11.12 95 49983 442750 110096471
Fluid retention 34.03 11.12 107 49971 94200 110445021
Cardiac failure congestive 33.95 11.12 147 49931 150853 110388368
Mental status changes 33.81 11.12 93 49985 76029 110463192
Ill-defined disorder 32.73 11.12 15 50063 156838 110382383
Hospice care 30.91 11.12 33 50045 12440 110526781
Flatulence 30.80 11.12 71 50007 52078 110487143
Influenza like illness 29.80 11.12 98 49980 88314 110450907
Bursitis 29.41 11.12 11 50067 129907 110409314
Headache 29.20 11.12 561 49517 881816 109657405
Hip fracture 29.13 11.12 55 50023 35096 110504125
Back pain 28.15 11.12 274 49804 370722 110168499
Multiple sclerosis relapse 28.14 11.12 67 50011 50173 110489048
Therapeutic product effect decreased 28.00 11.12 42 50036 244274 110294947
Overdose 27.97 11.12 39 50039 233755 110305466
Dyspnoea exertional 27.91 11.12 107 49971 103953 110435268
Haematocrit decreased 27.62 11.12 79 49999 66038 110473183
White blood cell count decreased 27.48 11.12 188 49890 229202 110310019
Urinary tract infection 27.26 11.12 246 49832 326036 110213185
Injection site pain 27.04 11.12 155 49923 177767 110361454
Prescribed overdose 26.50 11.12 4 50074 87577 110451644
Joint range of motion decreased 26.45 11.12 11 50067 121821 110417400
Blister 26.14 11.12 39 50039 227337 110311884
Mobility decreased 26.08 11.12 42 50036 237380 110301841
Blood potassium decreased 25.93 11.12 68 50010 54046 110485175
Pelvic pain 25.91 11.12 34 50044 15908 110523313
Viral infection 25.69 11.12 67 50011 53072 110486149
Hypercholesterolaemia 25.61 11.12 5 50073 90832 110448389
International normalised ratio increased 25.59 11.12 92 49986 86680 110452541
Constipation 25.57 11.12 261 49817 357525 110181696
Cellulitis 25.56 11.12 119 49959 125897 110413324
Injection site erythema 25.39 11.12 97 49981 94079 110445142
Peripheral venous disease 25.09 11.12 4 50074 84113 110455108
Asthma 25.01 11.12 47 50031 250244 110288977
Pulmonary arterial hypertension 24.60 11.12 49 50029 32519 110506702
Rheumatoid arthritis 24.40 11.12 63 50015 299550 110239671
Illness 24.30 11.12 4 50074 82167 110457054
Pulmonary hypertension 24.06 11.12 67 50011 55153 110484068
Pulmonary embolism 24.06 11.12 173 49905 214301 110324920
Small intestinal obstruction 23.77 11.12 48 50030 32165 110507056
Epilepsy 23.51 11.12 8 50070 100201 110439020
Grip strength decreased 23.49 11.12 4 50074 80170 110459051
Obesity 23.40 11.12 11 50067 113340 110425881
Injection site haemorrhage 22.94 11.12 48 50030 32980 110506241
Pleural effusion 22.70 11.12 148 49930 177561 110361660
Tremor 22.61 11.12 163 49915 202069 110337152
Neuropathy peripheral 22.10 11.12 148 49930 179129 110360092
Platelet count decreased 22 11.12 179 49899 230264 110308957
Gastrointestinal disorder 21.99 11.12 48 50030 241904 110297317
Hypoxia 21.80 11.12 116 49962 129399 110409822
Eye swelling 21.76 11.12 47 50031 33001 110506220
Cytokine release syndrome 21.76 11.12 3 50075 70303 110468918
Nasal congestion 21.57 11.12 95 49983 98187 110441034
Dysgeusia 21.32 11.12 75 50003 69910 110469311
Flushing 21.31 11.12 99 49979 104637 110434584
Complication associated with device 21.28 11.12 35 50043 20038 110519183
Oedema peripheral 21.25 11.12 235 49843 328425 110210796
Chills 20.95 11.12 153 49925 190427 110348794
Therapeutic response decreased 20.49 11.12 9 50069 96490 110442731
Cardiac disorder 20.10 11.12 78 50000 76202 110463019
Discomfort 20.00 11.12 42 50036 214665 110324556
Product complaint 19.98 11.12 28 50050 13944 110525277
Exposure during pregnancy 19.95 11.12 28 50050 167396 110371825
Weight decreased 19.92 11.12 310 49768 467747 110071474
Suicide attempt 19.90 11.12 11 50067 103383 110435838
Autoimmune disorder 19.79 11.12 3 50075 65480 110473741
Drug ineffective for unapproved indication 19.71 11.12 11 50067 102827 110436394
Impaired healing 19.60 11.12 37 50041 196680 110342541
Coma 19.35 11.12 15 50063 117854 110421367
Abdominal pain 19.32 11.12 333 49745 512656 110026565
Vaginal haemorrhage 19.27 11.12 38 50040 25036 110514185
Live birth 19.22 11.12 4 50074 69480 110469741
Wheezing 19.04 11.12 56 50022 255174 110284047
Bronchitis 18.98 11.12 129 49949 156903 110382318
Gastrointestinal haemorrhage 18.84 11.12 134 49944 165384 110373837
Condition aggravated 18.67 11.12 228 49850 734608 109804613
Atrial fibrillation 18.59 11.12 172 49906 229470 110309751
Bone pain 18.31 11.12 68 50010 65065 110474156
Transfusion 17.67 11.12 37 50041 25435 110513786
Chest pain 17.05 11.12 252 49826 376123 110163098
Inflammation 17.01 11.12 39 50039 193199 110346022
Laryngeal pain 16.95 11.12 17 50061 5958 110533263
Disease progression 16.93 11.12 177 49901 243857 110295364
Eosinophilia 16.74 11.12 3 50075 57933 110481288
Depression 16.61 11.12 218 49860 317117 110222104
Drug-induced liver injury 16.49 11.12 18 50060 120049 110419172
Hepatic function abnormal 16.47 11.12 10 50068 89285 110449936
Atelectasis 16.44 11.12 45 50033 36667 110502554
Myalgia 16.24 11.12 163 49915 222218 110317003
Red blood cell count decreased 16.23 11.12 66 50012 65857 110473364
Wound infection 16.19 11.12 12 50066 96453 110442768
Lung disorder 16.12 11.12 36 50042 180011 110359210
Hypersensitivity 16.04 11.12 112 49966 403886 110135335
Sleep disorder 15.99 11.12 42 50036 198602 110340619
Application site erythema 15.99 11.12 16 50062 5594 110533627
Liver disorder 15.77 11.12 25 50053 142218 110397003
Pain in jaw 15.72 11.12 55 50023 51122 110488099
Thrombosis 15.43 11.12 93 49985 108569 110430652
Heavy menstrual bleeding 15.32 11.12 27 50051 16338 110522883
Depressed level of consciousness 15.23 11.12 17 50061 112261 110426960
Gallbladder disorder 15.12 11.12 31 50047 20998 110518223
Stomatitis 15.04 11.12 67 50011 270175 110269046
Hypertension 15.02 11.12 153 49925 509931 110029290
Hypophagia 14.84 11.12 55 50023 52571 110486650
Infective pulmonary exacerbation of cystic fibrosis 14.65 11.12 25 50053 14746 110524475
Infection 14.58 11.12 100 49978 362100 110177121
Cardiac pacemaker insertion 14.44 11.12 16 50062 6285 110532936
Agranulocytosis 14.36 11.12 5 50073 61755 110477466
Hot flush 13.86 11.12 63 50015 65973 110473248
Vision blurred 13.84 11.12 103 49975 128919 110410302
Cholestasis 13.72 11.12 6 50072 64512 110474709
Gait disturbance 13.68 11.12 189 49889 278019 110261202
Rotator cuff syndrome 13.57 11.12 26 50052 16768 110522453
Blepharospasm 13.54 11.12 4 50074 54847 110484374
Cytomegalovirus infection 13.38 11.12 4 50074 54440 110484781
Influenza 13.35 11.12 126 49952 168975 110370246
Pulmonary fibrosis 13.25 11.12 16 50062 102026 110437195
Lethargy 13.23 11.12 80 49998 93496 110445725
Interstitial lung disease 13.19 11.12 27 50051 139307 110399914
Swelling face 13.10 11.12 79 49999 92242 110446979
Blood glucose decreased 13.06 11.12 36 50042 29452 110509769
Multiple organ dysfunction syndrome 13.05 11.12 31 50047 151679 110387542
Aspartate aminotransferase increased 13.04 11.12 120 49958 159816 110379405
Anxiety 12.97 11.12 224 49854 344854 110194367
Psoriasis 12.95 11.12 108 49970 139885 110399336
Nail disorder 12.95 11.12 5 50073 57930 110481291
Red blood cell sedimentation rate increased 12.81 11.12 10 50068 78292 110460929
Drug reaction with eosinophilia and systemic symptoms 12.79 11.12 11 50067 82084 110457137
Blood cholesterol increased 12.74 11.12 42 50036 184743 110354478
Hospitalisation 12.69 11.12 109 49969 142384 110396837
Application site pain 12.67 11.12 14 50064 5485 110533736
Balance disorder 12.48 11.12 93 49985 116467 110422754
Drug resistance 12.38 11.12 5 50073 56369 110482852
Application site discolouration 12.31 11.12 7 50071 1042 110538179
Blood glucose increased 12.14 11.12 102 49976 132394 110406827
Rash pruritic 12.10 11.12 81 49997 97988 110441233
Granulocytopenia 11.93 11.12 21 50057 12694 110526527
Rib fracture 11.89 11.12 38 50040 33732 110505489
Hepatitis 11.82 11.12 14 50064 90040 110449181
Syncope 11.82 11.12 142 49936 202394 110336827
Alopecia 11.75 11.12 107 49971 364646 110174575
Osteoarthritis 11.59 11.12 43 50035 182580 110356641
Intestinal dilatation 11.58 11.12 11 50067 3609 110535612
Therapy change 11.38 11.12 18 50060 9979 110529242
Metabolic encephalopathy 11.34 11.12 19 50059 11041 110528180
Transient ischaemic attack 11.24 11.12 58 50020 63924 110475297

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

SourceCodeDescription
CHEBI has role CHEBI:75835 anti-anaemic agent

Drug Use | Suggest Off label Use Form| |View source of the data|

None




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

None

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

IDSource
SFW1D987QV UNII
4032717 VANDF
C1721498 UMLSCUI
CHEBI:757203 CHEBI
CHEMBL4297753 ChEMBL_ID
9837124 PUBCHEM_CID
DB11210 DRUGBANK_ID
C510030 MESH_SUPPLEMENTAL_RECORD_UI
27755 MMSL
367012 MMSL
41445 MMSL
d07741 MMSL
009643 NDDF
1102188 RXNORM

Pharmaceutical products:

ProductCategoryIngredientsNDCFormQuantityRouteMarketingLabel
NESTABSPrenatal Multi-vitamin/Mineral Supplement HUMAN PRESCRIPTION DRUG LABEL 15 50967-219 TABLET, FILM COATED 32 mg ORAL unapproved drug other 8 sections
healthy mamaBE WELL ROUNDED BE WELL ROUNDED HUMAN PRESCRIPTION DRUG LABEL 17 58154-107 TABLET, FILM COATED 28 mg ORAL unapproved drug other 8 sections
Vitacore HUMAN PRESCRIPTION DRUG LABEL 12 84460-902 TABLET 20 mg ORAL unapproved drug other 11 sections
Florraxyl HUMAN PRESCRIPTION DRUG LABEL 12 84460-903 TABLET 20 mg ORAL unapproved drug other 10 sections
Folartex HUMAN PRESCRIPTION DRUG LABEL 12 85477-511 TABLET 20 mg ORAL unapproved drug other 10 sections
Folyra HUMAN PRESCRIPTION DRUG LABEL 12 85477-523 TABLET 20 mg ORAL unapproved drug other 10 sections
Folaten HUMAN PRESCRIPTION DRUG LABEL 12 85477-901 TABLET 20 mg ORAL unapproved drug other 10 sections
Folixia HUMAN PRESCRIPTION DRUG LABEL 12 85477-902 TABLET 20 mg ORAL unapproved drug other 11 sections
Nutralyn HUMAN PRESCRIPTION DRUG LABEL 12 85477-903 TABLET 20 mg ORAL unapproved drug other 11 sections
Aflora HUMAN PRESCRIPTION DRUG LABEL 12 85477-904 TABLET 20 mg ORAL unapproved drug other 12 sections