hydracarbazine Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
5125 3614-47-9

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • hydracarbazine
  • TH-2151
  • hydracarbazin
  • hydracarbizine
A hydrazinopyridazine-based diuretic with antihypertensive activity. Hydracarbazine is no longer marketed.
  • Molecular weight: 153.15
  • Formula: C5H7N5O
  • CLOGP: -1.60
  • LIPINSKI: 0
  • HAC: 6
  • HDO: 3
  • TPSA: 105.86
  • ALOGS: -1.77
  • ROTB: 1

Drug dosage:

None

ADMET properties:

None

Approvals:

None

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

Pharmacologic Action:

None

Drug Use (View source of the data)

None

Acid dissociation constants calculated using MoKa v3.0.0

Dissociation levelDissociation constantType (acidic/basic)
pKa1 8.33 acidic
pKa2 11.94 acidic
pKa3 11.23 Basic
pKa4 9.39 Basic
pKa5 3.31 Basic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

IDSource
6CTK2FB9QM UNII
1594 INN_ID
DB09243 DRUGBANK_ID
CHEBI:136055 CHEBI
CHEMBL2106246 ChEMBL_ID
71653 PUBCHEM_CID

Pharmaceutical products:

None