trenbolone hexahydrobenzylcarbonate 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | PK/Tox | Related Drugs | BioActivity |

Stem definitionDrug idCAS RN
anabolic steroids 5065 23454-33-3

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • trenbolone hexahydrobenzylcarbonate
  • parabolan
  • trenbolone cyclohexylmethylcarbonate
  • Molecular weight: 410.55
  • Formula: C26H34O4
  • CLOGP: 5.53
  • LIPINSKI: 1
  • HAC: 4
  • HDO: 0
  • TPSA: 52.60
  • ALOGS: -5.16
  • ROTB: 5

Drug dosage:

None

ADMET properties:

None

Predicted pharmacokinetic/toxicological properties (PK-AZ):

PropertyDescriptionValueUnitConfidenceSimilarity
kinase-safety-class ACVR2B,AURKA,AXL,BRAF,BTK,CAMK2D,CDK5,CDK9,DYRK1B,EIF2AK3,EPHB4,ERBB2,GRK2,GSK3B,ITK,JAK2,MAP2K6,MAP3K7,MAPK10,MAPK7,MAPKAPK2,NTRK2,PDK1,PDK4,PDPK1,PIK3CB,PIM2,PRKDC,STK33,TEK,TGFBR1,TTK 32
kinase-selectivity-class AXL,EIF2AK3,GRK2,STK33,TTK 5
pfas-class PFAS structural alert (1 = True, 0 = False) 0

Approvals:

None

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

None

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

SourceCodeDescription
MeSH PA D006728 Hormones
MeSH PA D045930 Anabolic Agents
CHEBI has role CHEBI:76924 plant metabolite
CHEBI has role CHEBI:138015 endocrine disruptor

Drug Use | Suggest Off label Use Form| |View source of the data|

None




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

None

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

TargetClassPharosUniProtActionTypeActivity value
(-log[M])		Mechanism
action		Bioact sourceMoA source
Androgen receptor Transcription factor IC50 8.58 CHEMBL
Polymerase acidic protein Enzyme Kd 4.04 CHEMBL

External reference:

IDSource
D08627 KEGG_DRUG
C0771657 UMLSCUI
20055297 PUBCHEM_CID
DB11551 DRUGBANK_ID
1484278 RXNORM
005817 NDDF
005818 NDDF
117059000 SNOMEDCT_US
C0076958 UMLSCUI
CHEBI:134706 CHEBI
CHEMBL1698011 ChEMBL_ID
10161-33-8 SECONDARY_CAS_RN
25015 PUBCHEM_CID
2916 INN_ID
D014204 MESH_DESCRIPTOR_UI
BNJ7Y3JFF2 UNII
P53R4420TR UNII
CHEBI:35018 CHEBI
P53R4420TR INXIGHT DRUGS

Pharmaceutical products:

None