Stem definition | Drug id | CAS RN |
---|---|---|
beta-adrenoreceptor antagonists | 487 | 57775-29-8 |
Molecule | Description |
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Synonyms:
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Source | Code | Description |
---|---|---|
MeSH PA | D018663 | Adrenergic Agents |
MeSH PA | D018674 | Adrenergic Antagonists |
MeSH PA | D000319 | Adrenergic beta-Antagonists |
MeSH PA | D018377 | Neurotransmitter Agents |
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Dissociation level | Dissociation constant | Type (acidic/basic) |
---|---|---|
pKa1 | 12.13 | acidic |
pKa2 | 9.19 | Basic |
None
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Target | Class | Pharos | UniProt | Action | Type | Activity value (-log[M]) | Mechanism action | Bioact source | MoA source |
---|---|---|---|---|---|---|---|---|---|
Beta-2 adrenergic receptor | GPCR | Ki | 9.94 | CHEMBL | |||||
Beta-3 adrenergic receptor | GPCR | AGONIST | Ki | 8.70 | IUPHAR | ||||
Beta-3 adrenergic receptor | GPCR | AGONIST | Ki | 7.70 | IUPHAR | ||||
Beta-3 adrenergic receptor | GPCR | AGONIST | Ki | 7.70 | IUPHAR | ||||
Beta-1 adrenergic receptor | GPCR | Ki | 10.05 | CHEMBL |
ID | Source |
---|---|
D07608 | KEGG_DRUG |
20192 | RXNORM |
C0054636 | UMLSCUI |
CHEBI:135261 | CHEBI |
CHEMBL324665 | ChEMBL_ID |
C014382 | MESH_SUPPLEMENTAL_RECORD_UI |
71739 | PUBCHEM_CID |
569 | IUPHAR_LIGAND_ID |
4036 | INN_ID |
29PW75S82A | UNII |
006896 | NDDF |
None