mebanazine 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
monoamine oxidase inhibitors, hydrazine derivatives 4865 65-64-5

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • mebanazine monooxalate
  • mebanazine sulfate
  • mebanazine monosulfate
  • mebanazine oxalate
  • mebanazine monohydrochloride
  • mebanazine hydrochloride
  • actomol
  • mebanazine
  • ICI-31397
  • Molecular weight: 136.20
  • Formula: C8H12N2
  • CLOGP: 1.01
  • LIPINSKI: 0
  • HAC: 2
  • HDO: 2
  • TPSA: 38.05
  • ALOGS: -1.11
  • ROTB: 2

Drug dosage:

None

ADMET properties:

None

Approvals:

None

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

None

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

None

Drug Use | Suggest Off label Use Form| |View source of the data|

DiseaseRelationSNOMED_IDDOID
Depressive disorder indication 35489007




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

Dissociation levelDissociation constantType (acidic/basic)
pKa1 7.35 Basic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

TargetClassPharosUniProtActionTypeActivity value
(-log[M])		Mechanism
action		Bioact sourceMoA source
Amine oxidase [flavin-containing] B Enzyme INHIBITOR SCIENTIFIC LITERATURE SCIENTIFIC LITERATURE
Amine oxidase [flavin-containing] A Enzyme INHIBITOR SCIENTIFIC LITERATURE SCIENTIFIC LITERATURE

External reference:

IDSource
Z5R55CJ4CG UNII
3979-76-8 SECONDARY_CAS_RN
34675-74-6 SECONDARY_CAS_RN
29248-55-3 SECONDARY_CAS_RN
C0065831 UMLSCUI
CHEBI:134728 CHEBI
CHEMBL1909283 ChEMBL_ID
6179 PUBCHEM_CID
DB09248 DRUGBANK_ID
1722 INN_ID
C004343 MESH_SUPPLEMENTAL_RECORD_UI

Pharmaceutical products:

None