caramiphen 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |
| Stem definition | Drug id | CAS RN |
|---|---|---|
| 486 | 77-22-5 |
Description:
| Molecule | Description |
|---|---|
|
Synonyms:
|
|
Drug dosage:
None
ADMET properties:
None
Approvals:
| Date | Agency | Company | Orphan |
|---|---|---|---|
| None | FDA |
FDA Adverse Event Reporting System (Female)
None
FDA Adverse Event Reporting System (Male)
None
FDA Adverse Event Reporting System (Geriatric)
None
FDA Adverse Event Reporting System (Pediatric)
None
Pharmacologic Action:
None
Drug Use | Suggest Off label Use Form| |View source of the data|
None
🐶 Veterinary Drug Use
| Species | Use | Relation |
|---|---|---|
| Dogs | Cough | Indication |
🐶 Veterinary products
| Product | Applicant | Ingredients |
|---|---|---|
| Carafen Cough Syrup, Carafen Cough Tablets | Zoetis Inc. | 2 |
Acid dissociation constants calculated using MoKa v3.0.0
| Dissociation level | Dissociation constant | Type (acidic/basic) |
|---|---|---|
| pKa1 | 8.51 | Basic |
Orange Book patent data (new drug applications)
None
Orange Book exclusivity data (new drug applications)
None
Bioactivity Summary:
| Target | Class | Pharos | UniProt | Action | Type | Activity value (-log[M]) | Mechanism action | Bioact source | MoA source |
|---|---|---|---|---|---|---|---|---|---|
| Sigma non-opioid intracellular receptor 1 | Membrane receptor | Ki | 7.81 | CHEMBL | |||||
| Lysosomal Pro-X carboxypeptidase | Enzyme | Ki | 7.59 | CHEMBL | |||||
| Muscarinic acetylcholine receptor M2 | GPCR | Ki | 7.50 | CHEMBL | |||||
| Muscarinic acetylcholine receptor M1 | GPCR | Ki | 8.92 | CHEMBL | |||||
| Sodium-dependent dopamine transporter | Transporter | Ki | 5.29 | CHEMBL |
External reference:
| ID | Source |
|---|---|
| 4019653 | VUID |
| N0000179066 | NUI |
| 125-85-9 | SECONDARY_CAS_RN |
| 133053 | RXNORM |
| C0054635 | UMLSCUI |
| CHEBI:135204 | CHEBI |
| CHEMBL61946 | ChEMBL_ID |
| CHEMBL1598472 | ChEMBL_ID |
| DB11504 | DRUGBANK_ID |
| C004519 | MESH_SUPPLEMENTAL_RECORD_UI |
| 6472 | PUBCHEM_CID |
| C000595810 | MESH_SUPPLEMENTAL_RECORD_UI |
| 1268 | INN_ID |
| 125-86-0 | SECONDARY_CAS_RN |
| 97J7NP0XJY | UNII |
| 4348 | MMSL |
| d03571 | MMSL |
| 412472003 | SNOMEDCT_US |
| 412473008 | SNOMEDCT_US |
| 96253007 | SNOMEDCT_US |
| 96315000 | SNOMEDCT_US |
| 4018017 | VANDF |
| 4019653 | VANDF |
| 001658 | NDDF |
| 001659 | NDDF |
| 001660 | NDDF |
Pharmaceutical products:
None