sodium thiosalicylate 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |
| Stem definition | Drug id | CAS RN |
|---|---|---|
| 4856 | 134-23-6 |
Description:
| Molecule | Description |
|---|---|
|
Synonyms:
|
a degradation product of thimerosal; RN given refers to parent cpd
|
Drug dosage:
None
ADMET properties:
None
Approvals:
None
FDA Adverse Event Reporting System (Female)
None
FDA Adverse Event Reporting System (Male)
None
FDA Adverse Event Reporting System (Geriatric)
None
FDA Adverse Event Reporting System (Pediatric)
None
Pharmacologic Action:
| Source | Code | Description |
|---|---|---|
| MeSH PA | D000700 | Analgesics |
| MeSH PA | D018712 | Analgesics, Non-Narcotic |
| MeSH PA | D002491 | Central Nervous System Agents |
| MeSH PA | D018373 | Peripheral Nervous System Agents |
| MeSH PA | D018689 | Sensory System Agents |
Drug Use | Suggest Off label Use Form| |View source of the data|
| Disease | Relation | SNOMED_ID | DOID |
|---|---|---|---|
| Rheumatic fever | indication | 58718002 | DOID:1586 |
| Osteoarthritis | indication | 396275006 |
🐶 Veterinary Drug Use
None
🐶 Veterinary products
None
Acid dissociation constants calculated using MoKa v3.0.0
| Dissociation level | Dissociation constant | Type (acidic/basic) |
|---|---|---|
| pKa1 | 3.76 | acidic |
| pKa2 | 6.38 | acidic |
Orange Book patent data (new drug applications)
None
Orange Book exclusivity data (new drug applications)
None
Bioactivity Summary:
| Target | Class | Pharos | UniProt | Action | Type | Activity value (-log[M]) | Mechanism action | Bioact source | MoA source |
|---|---|---|---|---|---|---|---|---|---|
| Histone deacetylase 8 | Enzyme | EC50 | 4.77 | CHEMBL |
External reference:
| ID | Source |
|---|---|
| 4019013 | VANDF |
| CHEBI:9182 | CHEBI |
| JKE | PDB_CHEM_ID |
| C026196 | MESH_SUPPLEMENTAL_RECORD_UI |
| C441201 | MESH_SUPPLEMENTAL_RECORD_UI |
| 147-93-3 | SECONDARY_CAS_RN |
| DB14026 | DRUGBANK_ID |
| 219648 | RXNORM |
| 1165 | MMSL |
| 3661 | MMSL |
| 5498 | MMSL |
| d00844 | MMSL |
| 001598 | NDDF |
| 25486007 | SNOMEDCT_US |
| 786423008 | SNOMEDCT_US |
| C0304347 | UMLSCUI |
| CHEMBL119888 | ChEMBL_ID |
| 23690429 | PUBCHEM_CID |
| C2D9ITW04B | UNII |
Pharmaceutical products:
None