seractide 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |
| Stem definition | Drug id | CAS RN |
|---|---|---|
| synthetic polypeptides with a corticotropin-like action | 4821 | 39295-97-1 |
Description:
| Molecule | Description |
|---|---|
|
Synonyms:
|
|
Drug dosage:
None
ADMET properties:
None
Approvals:
| Date | Agency | Company | Orphan |
|---|---|---|---|
| Feb. 21, 1978 | FDA | ARMOUR PHARM |
FDA Adverse Event Reporting System (Female)
None
FDA Adverse Event Reporting System (Male)
None
FDA Adverse Event Reporting System (Geriatric)
None
FDA Adverse Event Reporting System (Pediatric)
None
Pharmacologic Action:
None
Drug Use | Suggest Off label Use Form| |View source of the data|
None
🐶 Veterinary Drug Use
None
🐶 Veterinary products
None
Acid dissociation constants calculated using MoKa v3.0.0
| Dissociation level | Dissociation constant | Type (acidic/basic) |
|---|---|---|
| pKa1 | 3.04 | acidic |
| pKa2 | 3.37 | acidic |
| pKa3 | 3.56 | acidic |
| pKa4 | 3.89 | acidic |
| pKa5 | 4.04 | acidic |
| pKa6 | 4.19 | acidic |
| pKa7 | 4.43 | acidic |
| pKa8 | 9.43 | acidic |
| pKa9 | 10.05 | acidic |
| pKa10 | 12.17 | acidic |
| pKa11 | 12.36 | acidic |
| pKa12 | 12.56 | acidic |
| pKa13 | 12.83 | acidic |
| pKa14 | 12.9 | acidic |
| pKa15 | 13.02 | acidic |
| pKa16 | 13.09 | acidic |
| pKa17 | 13.32 | acidic |
| pKa18 | 13.37 | acidic |
| pKa19 | 13.42 | acidic |
| pKa20 | 13.63 | acidic |
| pKa21 | 13.64 | acidic |
| pKa22 | 13.7 | acidic |
| pKa23 | 13.76 | acidic |
| pKa24 | 13.79 | acidic |
| pKa25 | 13.9 | acidic |
| pKa26 | 13.93 | acidic |
| pKa27 | 11.5 | Basic |
| pKa28 | 11.26 | Basic |
| pKa29 | 11.01 | Basic |
| pKa30 | 10.81 | Basic |
| pKa31 | 10.55 | Basic |
| pKa32 | 10.3 | Basic |
| pKa33 | 9.94 | Basic |
| pKa34 | 7.62 | Basic |
| pKa35 | 6.69 | Basic |
Orange Book patent data (new drug applications)
None
Orange Book exclusivity data (new drug applications)
None
Bioactivity Summary:
| Target | Class | Pharos | UniProt | Action | Type | Activity value (-log[M]) | Mechanism action | Bioact source | MoA source |
|---|---|---|---|---|---|---|---|---|---|
| Adrenocorticotropic hormone receptor | GPCR | AGONIST | Ki | 8.01 | SCIENTIFIC LITERATURE | SCIENTIFIC LITERATURE |
External reference:
| ID | Source |
|---|---|
| IGM44CEY2I | UNII |
| D05827 | KEGG_DRUG |
| C1883003 | UMLSCUI |
| CHEBI:136033 | CHEBI |
| CHEMBL1201489 | ChEMBL_ID |
| 3532 | INN_ID |
| 6966 | IUPHAR_LIGAND_ID |
| DB09334 | DRUGBANK_ID |
| 1999800 | RXNORM |
| 63304-56-3 | SECONDARY_CAS_RN |
| 16132296 | PUBCHEM_CID |
Pharmaceutical products:
None