rose bengal 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
4637 632-69-9

Description:

MoleculeDescription

Synonyms:

  • rose bengal
  • Rose Bengal disodium
  • Rose Bengal sodium
  • Sodium tetraiodotetrachlorofluorescein
A bright bluish pink compound that has been used as a dye, biological stain, and diagnostic aid.
  • Molecular weight: 1017.63
  • Formula: C20H2Cl4I4Na2O5
  • CLOGP:
  • LIPINSKI: None
  • HAC: None
  • HDO: None
  • TPSA: 89.49
  • ALOGS:
  • ROTB: None

Drug dosage:

None

ADMET properties:

None

Approvals:

DateAgencyCompanyOrphan
None FDA

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

None

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

SourceCodeDescription
ATC S01JA02 SENSORY ORGANS
OPHTHALMOLOGICALS
DIAGNOSTIC AGENTS
Colouring agents
MeSH PA D004396 Coloring Agents
MeSH PA D005456 Fluorescent Dyes
MeSH PA D007202 Indicators and Reagents
MeSH PA D049408 Luminescent Agents

Drug Use | Suggest Off label Use Form| |View source of the data|

None




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

None

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

TargetClassPharosUniProtActionTypeActivity value
(-log[M])
Mechanism
action
Bioact sourceMoA source
Chymotrypsin C Enzyme IC50 4.30 CHEMBL
Beta-galactosidase Enzyme IC50 4.10 CHEMBL
Poly(ADP-ribose) glycohydrolase Enzyme IC50 4.53 CHEMBL
Beta-lactamase Enzyme IC50 6.33 CHEMBL
Vesicular acetylcholine transporter Transporter IC50 5.01 CHEMBL
Protein translocase subunit SecA 1 Unclassified IC50 6.30 CHEMBL
Protein translocase subunit SecA 2 Unclassified IC50 5.70 CHEMBL

External reference:

IDSource
4019275 VUID
N0000147474 NUI
4019275 VANDF
CHEMBL1208422 ChEMBL_ID
CHEMBL1160160 ChEMBL_ID
CHEMBL2359093 ChEMBL_ID
DB11182 DRUGBANK_ID
25474 PUBCHEM_CID
1362690 RXNORM
5073 MMSL
5436 MMSL
002215 NDDF
013981 NDDF
330888007 SNOMEDCT_US
408742009 SNOMEDCT_US
D012395 MESH_DESCRIPTOR_UI
C0035857 UMLSCUI
11874 INN_ID
956575SN5L UNII

Pharmaceutical products:

ProductCategoryIngredientsNDCFormQuantityRouteMarketingLabel
GloStrips HUMAN PRESCRIPTION DRUG LABEL 1 51801-004 STRIP 1.30 mg OPHTHALMIC UNAPPROVED DRUG OTHER 10 sections