polydatin Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
4613 27208-80-6

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • polydatin
  • polydotin peceid
  • pieceid
from Polygonum cuspidatum
  • Molecular weight: 390.39
  • Formula: C20H22O8
  • CLOGP: 1.52
  • LIPINSKI: 1
  • HAC: 8
  • HDO: 6
  • TPSA: 139.84
  • ALOGS: -2.71
  • ROTB: 5

Drug dosage:

None

ADMET properties:

None

Approvals:

DateAgencyCompanyOrphan
None FDA

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

Pharmacologic Action:

SourceCodeDescription
CHEBI has role CHEBI:22586 antioxidants
CHEBI has role CHEBI:25212 metabolites
CHEBI has role CHEBI:38070 antiarrhythmic agent
CHEBI has role CHEBI:62868 antihepatotoxic agent
CHEBI has role CHEBI:76595 nephroprotective agents

Drug Use (View source of the data)

None

Acid dissociation constants calculated using MoKa v3.0.0

Dissociation levelDissociation constantType (acidic/basic)
pKa1 6.51 acidic
pKa2 8.82 acidic
pKa3 11.99 acidic
pKa4 12.61 acidic
pKa5 13.44 acidic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

IDSource
C0071538 UMLSCUI
CHEBI:8198 CHEBI
DB11263 DRUGBANK_ID
C058229 MESH_SUPPLEMENTAL_RECORD_UI
XM261C37CQ UNII
5281718 PUBCHEM_CID
1364277 RXNORM

Pharmaceutical products:

ProductCategoryIngredientsNDCFormQuantityRouteMarketingLabel
Sooryehan Pure-Whitening HUMAN OTC DRUG LABEL 1 53208-441 CREAM 0.22 mL TOPICAL unapproved drug other 5 sections
Sooryehan Pure-Whitening Essence HUMAN OTC DRUG LABEL 1 53208-442 CREAM 0.22 1 TOPICAL unapproved drug other 5 sections
Sooryehan Pure Whitening Spot Treatment HUMAN OTC DRUG LABEL 1 53208-444 CREAM 0.21 mL TOPICAL OTC monograph not final 5 sections