DrugCentral 2023 🐕
2022 Update-Veterinary Drugs & Uses
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DrugCentral 2023 🐕
2022 Update-Veterinary Drugs & Uses
Search
Structure 🔎
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L1000
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FDA-approved
EMA-approved
PMDA-approved
Target Card Uniprot Example:
P23975
stearic acid 🐶
Veterinary Use |
Indications/Contra
| FAERs-F
| FAERs-M
| Orange Bk
| BioActivity |
Stem definition
Drug id
CAS RN
4611
57-11-4
Description:
Molecule
Description
Molfile
Inchi
Smiles
Synonyms:
stearic acid
octadecanoic acid
Molecular weight: 284.48
Formula: C18H36O2
CLOGP: 8.27
LIPINSKI: 1
HAC: 2
HDO: 1
TPSA: 37.30
ALOGS: -6.63
ROTB: 16
Drug dosage:
None
ADMET properties:
None
Approvals:
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Date
Agency
Company
Orphan
None
FDA
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FDA Adverse Event Reporting System (Female)
None
FDA Adverse Event Reporting System (Male)
None
FDA Adverse Event Reporting System (Geriatric)
None
FDA Adverse Event Reporting System (Pediatric)
None
Pharmacologic Action:
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Source
Code
Description
CHEBI has role
CHEBI:76924
plant metabolites
CHEBI has role
CHEBI:77746
Homo sapiens metabolite
CHEBI has role
CHEBI:83056
Daphnia magna metabolites
CHEBI has role
CHEBI:84735
algal metabolites
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Drug Use
| Suggest Off label Use Form|
|View source of the data|
None
🐶 Veterinary Drug Use
None
🐶 Veterinary products
None
Acid dissociation constants calculated using MoKa v3.0.0
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Dissociation level
Dissociation constant
Type (acidic/basic)
pKa1
4.76
acidic
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Orange Book patent data (new drug applications)
None
Orange Book exclusivity data (new drug applications)
None
Bioactivity Summary:
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Target
Class
Pharos
UniProt
Action
Type
Activity value
(-log[M])
Mechanism
action
Bioact source
MoA source
Peroxisome proliferator-activated receptor alpha
Nuclear hormone receptor
Q07869
PPARA_HUMAN
IC50
5.96
CHEMBL
Peroxisome proliferator-activated receptor gamma
Nuclear hormone receptor
P37231
PPARG_HUMAN
IC50
4.52
CHEMBL
Tyrosine-protein phosphatase non-receptor type 1
Enzyme
P18031
PTN1_HUMAN
IC50
5.64
CHEMBL
Fatty acid-binding protein, adipocyte
Cytosolic other
P15090
FABP4_HUMAN
Kd
4.10
CHEMBL
Peroxisome proliferator-activated receptor delta
Nuclear hormone receptor
Q03181
PPARD_HUMAN
IC50
5.22
CHEMBL
Acetylcholinesterase
Enzyme
ACES_ELEEL
Ki
5.44
CHEMBL
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External reference:
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entries
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ID
Source
STE
PDB_CHEM_ID
003887
NDDF
1310551
RXNORM
259577009
SNOMEDCT_US
3377
IUPHAR_LIGAND_ID
4020443
VUID
4020443
VANDF
420674004
SNOMEDCT_US
4ELV7Z65AP
UNII
5281
PUBCHEM_CID
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Pharmaceutical products:
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Product
Category
Ingredients
NDC
Form
Quantity
Route
Marketing
Label
Anubis Barcelona Spa Line
HUMAN OTC DRUG LABEL
22
83021-305
CREAM
1 g
TOPICAL
OTC monograph final
9 sections
Anubis Barcelona Spa Line
HUMAN OTC DRUG LABEL
22
83021-305
CREAM
1 g
TOPICAL
OTC monograph final
9 sections
CELLBN FIRST CARE CLEANSER
HUMAN OTC DRUG LABEL
1
71450-0006
CREAM
16 g
TOPICAL
unapproved drug other
7 sections
Doctor Plus
HUMAN OTC DRUG LABEL
1
70042-6001
CREAM
1.50 g
TOPICAL
unapproved drug other
7 sections
ISA KNOX AGELESS SERUM MAKEUP BASE 10
HUMAN OTC DRUG LABEL
6
53208-471
CREAM
0.18 mL
TOPICAL
OTC monograph not final
5 sections
ISAKNOX AGELESS SERUM MOIST PEARL BASE
HUMAN OTC DRUG LABEL
6
53208-478
LIQUID
0.18 mL
TOPICAL
OTC monograph not final
5 sections
Jinhwagwangsu Bubble
HUMAN OTC DRUG LABEL
1
69871-001
SOAP
120 mg
TOPICAL
unapproved drug other
7 sections
Jinhwagwangsu Hair
HUMAN OTC DRUG LABEL
1
69871-004
SOAP
12 g
TOPICAL
unapproved drug other
7 sections
Obeo Baby Bubble
HUMAN OTC DRUG LABEL
1
69871-002
SOAP
120 mg
TOPICAL
unapproved drug other
7 sections
RECOVERY
HUMAN OTC DRUG LABEL
1
70042-0002
CREAM
1.50 g
TOPICAL
unapproved drug other
7 sections
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stearic acid