DrugCentral 2023 🐕
2022 Update-Veterinary Drugs & Uses
Search
Structure 🔎
Similarity 🔎
Smart API
Redial
About
Download
L1000
FAQ
DrugCentral 2023 🐕
2022 Update-Veterinary Drugs & Uses
Search
Structure 🔎
Similarity 🔎
Smart API
Redial
About
Download
L1000
FAQ
Scroll
All
FDA-approved
EMA-approved
PMDA-approved
Target Card Uniprot Example:
P23975
diosmetin 🐶
Veterinary Use |
Indications/Contra
| FAERs-F
| FAERs-M
| Orange Bk
| BioActivity |
Stem definition
Drug id
CAS RN
4601
520-34-3
Description:
Molecule
Description
Molfile
Inchi
Smiles
Synonyms:
diosmetine
diosmetin
a 5,7-dihydroxyflavone
Molecular weight: 300.27
Formula: C16H12O6
CLOGP: 2.75
LIPINSKI: 0
HAC: 6
HDO: 3
TPSA: 96.22
ALOGS: -3.60
ROTB: 2
Drug dosage:
None
ADMET properties:
None
Approvals:
Show
10
25
50
100
entries
Search:
Date
Agency
Company
Orphan
None
FDA
Showing 1 to 1 of 1 entries
Previous
1
Next
FDA Adverse Event Reporting System (Female)
None
FDA Adverse Event Reporting System (Male)
None
FDA Adverse Event Reporting System (Geriatric)
None
FDA Adverse Event Reporting System (Pediatric)
None
Pharmacologic Action:
Show
10
25
50
100
entries
Search:
Source
Code
Description
CHEBI has role
CHEBI:22586
antioxidants
CHEBI has role
CHEBI:35610
antineoplastic agents
CHEBI has role
CHEBI:35620
vasodilator agents
CHEBI has role
CHEBI:48422
angiogenesis antagonist
CHEBI has role
CHEBI:50646
antiosteoporotic
CHEBI has role
CHEBI:67079
anti-inflammatory agents
CHEBI has role
CHEBI:68495
Type I cell-death inducers
CHEBI has role
CHEBI:76924
plant metabolites
CHEBI has role
CHEBI:77307
cardioprotective agents
CHEBI has role
CHEBI:140489
TrkB receptor agonist
Showing 1 to 10 of 10 entries
Previous
1
Next
Drug Use
| Suggest Off label Use Form|
|View source of the data|
None
🐶 Veterinary Drug Use
None
🐶 Veterinary products
None
Acid dissociation constants calculated using MoKa v3.0.0
Show
10
25
50
100
entries
Search:
Dissociation level
Dissociation constant
Type (acidic/basic)
pKa1
5.68
acidic
pKa2
9.12
acidic
pKa3
10.43
acidic
Showing 1 to 3 of 3 entries
Previous
1
Next
Orange Book patent data (new drug applications)
None
Orange Book exclusivity data (new drug applications)
None
Bioactivity Summary:
Show
10
25
50
100
entries
Search:
Target
Class
Pharos
UniProt
Action
Type
Activity value
(-log[M])
Mechanism
action
Bioact source
MoA source
Multidrug resistance-associated protein 1
Transporter
P33527
MRP1_HUMAN
IC50
5.52
CHEMBL
Cytochrome P450 1B1
Enzyme
Q16678
CP1B1_HUMAN
IC50
7.54
CHEMBL
Lysine-specific histone demethylase 1A
Enzyme
O60341
KDM1A_HUMAN
IC50
4.55
CHEMBL
Inositol polyphosphate multikinase
Kinase
Q8NFU5
IPMK_HUMAN
IC50
5.14
CHEMBL
Inositol hexakisphosphate kinase 2
Kinase
Q9UHH9
IP6K2_HUMAN
IC50
6.05
CHEMBL
Showing 1 to 5 of 5 entries
Previous
1
Next
External reference:
Show
10
25
50
100
entries
Search:
ID
Source
J8D
PDB_CHEM_ID
1314347
RXNORM
5281612
PUBCHEM_CID
C0114217
UMLSCUI
C039602
MESH_SUPPLEMENTAL_RECORD_UI
CHEBI:4630
CHEBI
CHEMBL90568
ChEMBL_ID
DB11259
DRUGBANK_ID
TWZ37241OT
UNII
Showing 1 to 9 of 9 entries
Previous
1
Next
Pharmaceutical products:
Show
10
25
50
100
entries
Search:
Product
Category
Ingredients
NDC
Form
Quantity
Route
Marketing
Label
GONGJINHYANG SEOL WHITENING
HUMAN OTC DRUG LABEL
1
53208-372
CREAM
0.10 g
TOPICAL
OTC monograph not final
12 sections
ISA KNOX WXII PLUS WHITENING REVOLUTION SERUM
HUMAN OTC DRUG LABEL
1
53208-424
CREAM
0.11 mL
TOPICAL
OTC monograph not final
10 sections
ISAKNOX X202 WHITENING SECRET ESSENCE
HUMAN OTC DRUG LABEL
1
53208-531
CREAM
0.06 mL
TOPICAL
unapproved drug other
9 sections
Whoo Gongjinhyang Seol Whitening Jin Essence
HUMAN OTC DRUG LABEL
1
53208-427
CREAM
0.06 mL
TOPICAL
unapproved drug other
12 sections
Showing 1 to 4 of 4 entries
Previous
1
Next
Search
Structure 🔎
Similarity 🔎
Smart API
Redial
About
Download
L1000
FAQ
diosmetin