manganese sulfate 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | PK/Tox | Related Drugs | BioActivity |

Stem definitionDrug idCAS RN
4461 7785-87-7

Description:

MoleculeDescription

Synonyms:

  • manganese sulfate
  • Molecular weight: 150.99
  • Formula: MnO4S
  • CLOGP:
  • LIPINSKI: None
  • HAC: None
  • HDO: None
  • TPSA: 80.26
  • ALOGS:
  • ROTB: None

Drug dosage:

None

ADMET properties:

None

Predicted pharmacokinetic/toxicological properties (PK-AZ):

None

Approvals:

DateAgencyCompanyOrphan
None FDA

FDA Adverse Event Reporting System (Female)

MedDRA adverse event termLikelihood ratioLikelihood ratio thresholdPatients taking drug having adverse eventPatients taking drug not having adverse eventPatients not taking drug having adverse eventPatients not taking drug not having adverse event
Pemphigus 1727.90 9.87 6471 776368 320393 89525215
Systemic lupus erythematosus 1716.68 9.87 6923 775916 354973 89490635
Glossodynia 1473.40 9.87 6090 776749 315689 89529919
Hand deformity 1230.45 9.87 5446 777393 290916 89554692
Arthropathy 1196.51 9.87 6281 776558 359961 89485647
Abdominal discomfort 1077.58 9.87 7433 775406 469895 89375713
Alopecia 1064.84 9.87 7619 775220 487452 89358156
Wound 1001.33 9.87 5214 777625 297766 89547842
Completed suicide 981.96 9.87 70 782769 144988 89700620
Toxicity to various agents 898.64 9.87 702 782137 287144 89558464
Synovitis 893.85 9.87 5380 777459 324372 89521236
Maternal exposure during pregnancy 852.29 9.87 5675 777164 354388 89491220
Anti-cyclic citrullinated peptide antibody positive 831.96 9.87 4142 778697 232291 89613317
Swelling 831.69 9.87 6329 776510 412729 89432879
Pericarditis 826.26 9.87 4552 778287 265599 89580009
Contraindicated product administered 740.07 9.87 5017 777822 315122 89530486
Discomfort 738.05 9.87 4468 778371 269867 89575741
Joint swelling 681.43 9.87 6990 775849 496310 89349298
Duodenal ulcer perforation 674.55 9.87 3726 779113 217562 89628046
Infusion related reaction 639.06 9.87 5942 776897 410838 89434770
Helicobacter infection 621.63 9.87 3713 779126 223137 89622471
Death 589.51 9.87 1998 780841 454553 89391055
Intentional overdose 554.99 9.87 76 782763 93758 89751850
Drug interaction 543.58 9.87 972 781867 275481 89570127
Rheumatoid arthritis 527.33 9.87 5113 777726 357501 89488107
Rheumatoid factor positive 496.90 9.87 2851 779988 168799 89676809
Pain 483.32 9.87 11628 771211 984713 88860895
Psoriatic arthropathy 452.82 9.87 3450 779389 224885 89620723
Febrile neutropenia 450.12 9.87 422 782417 157927 89687681
Hepatic enzyme increased 429.40 9.87 4885 777954 355851 89489757
Drug abuse 403.75 9.87 106 782733 82241 89763367
Therapeutic product effect decreased 391.54 9.87 3890 778949 273681 89571927
Suicide attempt 381.39 9.87 91 782748 75308 89770300
Arthralgia 365.80 9.87 9050 773789 769472 89076136
Musculoskeletal stiffness 363.33 9.87 4039 778800 292493 89553115
Impaired healing 358.26 9.87 3339 779500 230860 89614748
Product use issue 350.38 9.87 4372 778467 325547 89520061
Malignant neoplasm progression 345.54 9.87 251 782588 106619 89738989
Disease progression 344.78 9.87 511 782328 156104 89689504
Constipation 339.49 9.87 1260 781579 279135 89566473
Depressed level of consciousness 332.40 9.87 107 782732 72677 89772931
Folliculitis 324.90 9.87 2938 779901 201415 89644193
Acute kidney injury 314.14 9.87 1560 781279 318827 89526781
Rheumatic fever 313.19 9.87 2331 780508 150790 89694818
Neutropenia 308.74 9.87 957 781882 223947 89621661
Blister 302.16 9.87 3451 779388 251547 89594061
Cardiac arrest 293.08 9.87 284 782555 104651 89740957
Overdose 286.56 9.87 581 782258 157128 89688480
Drug intolerance 279.42 9.87 5422 777417 442169 89403439
Muscle injury 269.74 9.87 2518 780321 174136 89671472
Electrocardiogram QT prolonged 266.05 9.87 147 782692 72309 89773299
Sleep disorder due to general medical condition, insomnia type 258.54 9.87 1951 780888 126743 89718865
Irritable bowel syndrome 255.43 9.87 2829 780010 204619 89640989
Swollen joint count increased 251.14 9.87 1734 781105 109472 89736136
Type 2 diabetes mellitus 245.83 9.87 2762 780077 200482 89645126
Lactic acidosis 241.64 9.87 68 782771 50395 89795213
Fibromyalgia 240.44 9.87 2783 780056 203486 89642122
Nausea 240.26 9.87 7537 775302 1102779 88742829
Hyperhidrosis 239.31 9.87 512 782327 135793 89709815
Hypersensitivity 238.41 9.87 5369 777470 449308 89396300
Exposure during pregnancy 236.25 9.87 3120 779719 235290 89610318
Treatment failure 233.68 9.87 3806 779033 300122 89545486
Somnolence 228.59 9.87 978 781861 208106 89637502
Nasopharyngitis 226.65 9.87 4849 777990 402255 89443353
Hypotension 225.19 9.87 1765 781074 323632 89521976
Hip arthroplasty 221.78 9.87 1268 781571 74940 89770668
Lower respiratory tract infection 220.67 9.87 3212 779627 247447 89598161
Hyponatraemia 219.45 9.87 520 782319 133018 89712590
Knee arthroplasty 217.66 9.87 1346 781493 81836 89763772
Sedation 216.12 9.87 73 782766 48098 89797510
Blood cholesterol increased 212.68 9.87 2738 780101 205274 89640334
C-reactive protein abnormal 210.08 9.87 1847 780992 125582 89720026
Ill-defined disorder 201.98 9.87 2464 780375 182427 89663181
Cardiac failure 196.65 9.87 406 782433 109090 89736518
Drug ineffective for unapproved indication 190.02 9.87 177 782662 66467 89779141
Bradycardia 189.96 9.87 268 782571 83579 89762029
Stomatitis 181.22 9.87 3357 779482 271341 89574267
Liver injury 178.93 9.87 2256 780583 168311 89677297
Drug reaction with eosinophilia and systemic symptoms 173.24 9.87 76 782763 42682 89802926
Red blood cell sedimentation rate abnormal 173.08 9.87 531 782308 23673 89821935
Tremor 172.01 9.87 709 782130 152464 89693144
Agitation 170.09 9.87 197 782642 66901 89778707
Anaemia 168.69 9.87 2093 780746 350709 89494899
Neoplasm progression 166.61 9.87 88 782751 44398 89801210
Serotonin syndrome 165.52 9.87 60 782779 37827 89807781
Renal failure 165.50 9.87 578 782261 130429 89715179
Cognitive disorder 163.12 9.87 216 782623 69191 89776417
Myelosuppression 161.63 9.87 135 782704 53456 89792152
Diarrhoea 160.85 9.87 6559 776280 932631 88912977
Contusion 159.45 9.87 3052 779787 248164 89597444
Renal impairment 157.37 9.87 431 782408 104990 89740618
Rhabdomyolysis 157.21 9.87 127 782712 51129 89794479
Osteoarthritis 156.27 9.87 2467 780372 193263 89652345
Thrombocytopenia 150.02 9.87 1120 781719 207605 89638003
Coma 149.30 9.87 248 782591 72384 89773224
Intentional product use issue 145.58 9.87 2658 780181 214234 89631374
Chest discomfort 143.45 9.87 660 782179 137705 89707903
Angioedema 143.37 9.87 211 782628 64665 89780943
Sickle cell anaemia with crisis 142.60 9.87 239 782600 7058 89838550
Syncope 141.61 9.87 626 782213 132037 89713571
Hypoglycaemia 141.26 9.87 241 782598 69607 89776001
Sopor 140.96 9.87 22 782817 24622 89820986
Injury 140.42 9.87 2441 780398 194908 89650700
Neuropathy peripheral 139.84 9.87 657 782182 136313 89709295
Off label use 138.10 9.87 7955 774884 1094297 88751311
Respiratory failure 138.07 9.87 540 782299 117878 89727730
No adverse event 136.17 9.87 236 782603 67746 89777862
Macular degeneration 135.15 9.87 80 782759 37890 89807718
Drug resistance 135.11 9.87 47 782792 30402 89815206
Respiratory arrest 133.71 9.87 60 782779 33251 89812357
Myalgia 132.96 9.87 925 781914 174200 89671408
Pregnancy 131.00 9.87 952 781887 61095 89784513
Joint range of motion decreased 126.38 9.87 1756 781083 133887 89711721
Metabolic acidosis 126.06 9.87 178 782661 55498 89790110
Intentional self-injury 125.55 9.87 48 782791 29286 89816322
General physical health deterioration 124.78 9.87 3981 778858 351134 89494474
Facet joint syndrome 123.39 9.87 1347 781492 97042 89748566
Cytokine release syndrome 122.71 9.87 44 782795 27929 89817679
Neutrophil count decreased 121.97 9.87 273 782566 71259 89774349
Sinusitis 121.80 9.87 3851 778988 339237 89506371
Multiple organ dysfunction syndrome 119.65 9.87 257 782582 68079 89777529
Intentional product misuse 119.54 9.87 386 782453 89218 89756390
Hepatic function abnormal 119.39 9.87 134 782705 46154 89799454
Grip strength decreased 119.14 9.87 1274 781565 91302 89754306
Weight increased 118.69 9.87 4572 778267 413355 89432253
Inflammation 118.19 9.87 2184 780655 176408 89669200
Live birth 116.86 9.87 1120 781719 77987 89767621
Peripheral swelling 116.31 9.87 4515 778324 408591 89437017
Cardio-respiratory arrest 116.01 9.87 231 782608 62909 89782699
COVID-19 114.28 9.87 921 781918 167922 89677686
Fatigue 114.03 9.87 11503 771336 1142520 88703088
Hepatic failure 112.68 9.87 106 782733 39622 89805986
Seizure 112.52 9.87 813 782026 151816 89693792
Vision blurred 112.01 9.87 530 782309 109763 89735845
Tachycardia 111.87 9.87 849 781990 156824 89688784
Hyperglycaemia 111.43 9.87 167 782672 50803 89794805
White blood cell count decreased 110.15 9.87 918 781921 166191 89679417
Sedation complication 109.54 9.87 10 782829 16934 89828674
Orthostatic hypotension 109.07 9.87 120 782719 41707 89803901
Palpitations 108.86 9.87 712 782127 136016 89709592
Rash 107.52 9.87 8122 774717 787978 89057630
Mobility decreased 106.92 9.87 2880 779959 247854 89597754
Balance disorder 106.70 9.87 453 782386 96627 89748981
Dry skin 106.30 9.87 396 782443 87677 89757931
Multiple sclerosis relapse 106.20 9.87 180 782659 52125 89793483
Altered state of consciousness 105.94 9.87 71 782768 31461 89814147
Dysphagia 105.73 9.87 554 782285 111724 89733884
Dyspnoea 104.91 9.87 6387 776452 874568 88971040
Device expulsion 104.75 9.87 119 782720 40767 89804841
Blood glucose increased 104.34 9.87 445 782394 94801 89750807
Hypoxia 104.34 9.87 301 782538 72098 89773510
Accidental exposure to product 103.53 9.87 128 782711 42238 89803370
Pulmonary fibrosis 101.47 9.87 1395 781444 106108 89739500
Dehydration 101.14 9.87 1132 781707 193315 89652293
Deep vein thrombosis postoperative 99.93 9.87 993 781846 69816 89775792
Condition aggravated 99.52 9.87 6185 776654 589360 89256248
Metastases to bone 99.19 9.87 48 782791 25457 89820151
Anaphylactic reaction 95.22 9.87 410 782429 87114 89758494
Lip dry 94.86 9.87 1309 781530 99646 89745962
Blood pressure systolic abnormal 94.64 9.87 376 782463 19102 89826506
Product dose omission issue 94.40 9.87 1863 780976 289824 89555784
Blood pressure diastolic abnormal 94.37 9.87 381 782458 19500 89826108
Palmar-plantar erythrodysaesthesia syndrome 94.28 9.87 63 782776 27960 89817648
Platelet count decreased 94.13 9.87 744 782095 136225 89709383
Infection 93.43 9.87 3921 778918 358173 89487435
Drug withdrawal syndrome 93.41 9.87 67 782772 28656 89816952
Erythema 93.27 9.87 1405 781434 227841 89617767
Encephalopathy 93.22 9.87 161 782678 46283 89799325
Shock 92.46 9.87 68 782771 28710 89816898
Dysarthria 91.20 9.87 210 782629 54272 89791336
Suicidal ideation 91.15 9.87 329 782510 73526 89772082
Hepatocellular injury 91.01 9.87 70 782769 28888 89816720
Feeling abnormal 90.80 9.87 964 781875 166271 89679337
Anaphylactic shock 90.09 9.87 84 782755 31533 89814075
Colitis 90.06 9.87 306 782533 69636 89775972
Food allergy 88.83 9.87 55 782784 25423 89820185
Hyperkalaemia 88.65 9.87 277 782562 64687 89780921
Temperature regulation disorder 88.12 9.87 11 782828 14568 89831040
Vomiting 87.74 9.87 5750 777089 782543 89063065
Creatinine renal clearance decreased 87.68 9.87 27 782812 18872 89826736
Hallucination 87.38 9.87 285 782554 65674 89779934
Restlessness 87.20 9.87 108 782731 35612 89809996
Wrong technique in product usage process 86.89 9.87 321 782518 71250 89774358
Sepsis 86.87 9.87 1064 781775 178750 89666858
Skin exfoliation 86.17 9.87 299 782540 67614 89777994
Rash erythematous 83.71 9.87 285 782554 64819 89780789
Ejection fraction decreased 83.10 9.87 63 782776 26190 89819418
Obesity 82.70 9.87 1326 781513 104181 89741427
Anxiety 82.61 9.87 2040 780799 307732 89537876
Cardiac failure congestive 81.59 9.87 508 782331 98186 89747422
Disability assessment scale score increased 81.19 9.87 132 782707 3799 89841809
Drug dependence 81.13 9.87 80 782759 29247 89816361
Asthenia 80.99 9.87 3776 779063 529975 89315633
Cytomegalovirus infection 80.23 9.87 67 782772 26535 89819073
Mydriasis 80.20 9.87 16 782823 14996 89830612
Ventricular tachycardia 79.88 9.87 58 782781 24650 89820958
Autoimmune disorder 79.54 9.87 1013 781826 75731 89769877
Leukopenia 79.37 9.87 526 782313 100184 89745424
Blood calcium decreased 79.35 9.87 86 782753 30096 89815512
Disturbance in attention 79.32 9.87 181 782658 46928 89798680
Diabetic ketoacidosis 79.29 9.87 57 782782 24350 89821258
Abortion spontaneous 77.70 9.87 761 782078 53295 89792313
Joint effusion 77.62 9.87 357 782482 19353 89826255
Wound infection 77.40 9.87 1321 781518 105081 89740527
Foot deformity 77.25 9.87 822 782017 58829 89786779
Back pain 76.83 9.87 2118 780721 315057 89530551
C-reactive protein increased 76.29 9.87 2080 780759 179309 89666299
Arthritis 76.26 9.87 1939 780900 165376 89680232
Cholestasis 75.47 9.87 123 782716 36176 89809432
Red blood cell sedimentation rate increased 74.39 9.87 1063 781776 81532 89764076
Neurotoxicity 73.93 9.87 47 782792 21420 89824188
Metastases to liver 73.63 9.87 84 782755 28723 89816885
Schizophrenia 73.47 9.87 19 782820 14895 89830713
Drug level increased 73.10 9.87 79 782760 27683 89817925
Cough 72.75 9.87 2532 780307 366430 89479178
Flushing 72.37 9.87 457 782382 88034 89757574
Blood creatinine increased 72.33 9.87 545 782294 100841 89744767
Blood pressure systolic increased 71.86 9.87 796 782043 57549 89788059
Myocardial infarction 71.71 9.87 578 782261 105394 89740214
Personality disorder 71.42 9.87 11 782828 12433 89833175
Ascites 71.36 9.87 195 782644 47545 89798063
Sciatica 71.34 9.87 1252 781587 100130 89745478
Product use in unapproved indication 71.32 9.87 2286 780553 333950 89511658
Gamma-glutamyltransferase increased 71.32 9.87 137 782702 37815 89807793
Respiratory depression 70.92 9.87 23 782816 15552 89830056
Blood pressure decreased 70.81 9.87 369 782470 74526 89771082
Hypercholesterolaemia 70.65 9.87 1245 781594 99647 89745961
Acute hepatic failure 69.06 9.87 56 782783 22505 89823103
Hypokalaemia 68.28 9.87 763 782076 130353 89715255
Blood creatine phosphokinase increased 67.32 9.87 119 782720 33904 89811704
Dermatitis atopic 67.30 9.87 62 782777 23410 89822198
Osteonecrosis of jaw 66.85 9.87 149 782690 38954 89806654
Disorientation 66.84 9.87 179 782660 43935 89801673
Blood pressure fluctuation 66.82 9.87 720 782119 51693 89793915
Breast cancer stage III 66.81 9.87 1063 781776 83384 89762224
Extrapyramidal disorder 66.01 9.87 29 782810 16274 89829334
Device difficult to use 65.13 9.87 35 782804 17490 89828118
Joint destruction 64.96 9.87 257 782582 13030 89832578
Torsade de pointes 64.71 9.87 25 782814 15157 89830451
Chronic sinusitis 64.62 9.87 66 782773 23736 89821872
Bursitis 64.55 9.87 1541 781298 130113 89715495
Adjustment disorder with depressed mood 64.38 9.87 762 782077 55991 89789617
Fluid retention 64.05 9.87 471 782368 87620 89757988
Pulmonary embolism 63.96 9.87 772 782067 130048 89715560
Aphasia 63.90 9.87 175 782664 42637 89802971
Musculoskeletal pain 63.80 9.87 1934 780905 169317 89676291
Metastases to central nervous system 63.79 9.87 36 782803 17506 89828102
Dislocation of vertebra 63.72 9.87 752 782087 55216 89790392
Cerebral haemorrhage 63.67 9.87 126 782713 34396 89811212
Peripheral venous disease 63.27 9.87 1048 781791 82873 89762735
Blood bilirubin increased 63.17 9.87 180 782659 43290 89802318
Disease recurrence 63.13 9.87 145 782694 37508 89808100
Blood alkaline phosphatase increased 62.81 9.87 209 782630 47870 89797738
Unresponsive to stimuli 62.15 9.87 149 782690 37972 89807636
Parkinsonism 61.91 9.87 22 782817 14043 89831565
Depressed mood 61.78 9.87 224 782615 49998 89795610
Gastrointestinal disorder 61.78 9.87 2760 780079 253927 89591681
Gait inability 61.74 9.87 1680 781159 144776 89700832
Poisoning 61.72 9.87 27 782812 15190 89830418
Emotional distress 61.61 9.87 141 782698 36521 89809087
Adverse event 61.15 9.87 1386 781453 116032 89729576
Bone erosion 61.07 9.87 714 782125 52307 89793301
Juvenile idiopathic arthritis 60.74 9.87 117 782722 3860 89841748
Loss of consciousness 60.68 9.87 849 781990 139389 89706219
Hemiparesis 60.54 9.87 114 782725 31705 89813903
Procedural pain 60.46 9.87 123 782716 33237 89812371
Foetal exposure during pregnancy 60.30 9.87 602 782237 42373 89803235
Posterior reversible encephalopathy syndrome 59.45 9.87 63 782776 22276 89823332
Disseminated intravascular coagulation 59.30 9.87 59 782780 21479 89824129
Thrombotic microangiopathy 59.16 9.87 31 782808 15712 89829896
Therapy partial responder 58.85 9.87 62 782777 21981 89823627
Polyarthritis 58.49 9.87 313 782526 18037 89827571
Withdrawal syndrome 58.31 9.87 65 782774 22459 89823149
Cerebrovascular accident 58.13 9.87 735 782104 122798 89722810
Exposure via skin contact 58.05 9.87 11 782828 10694 89834914
Hemiplegia 57.58 9.87 34 782805 16126 89829482
Vertigo 57.35 9.87 360 782479 69451 89776157
Akathisia 57.35 9.87 13 782826 11146 89834462
Chronic kidney disease 57.14 9.87 231 782608 49960 89795648
Bone pain 57.14 9.87 308 782531 61675 89783933
Hypothermia 56.59 9.87 32 782807 15543 89830065
Road traffic accident 56.54 9.87 1272 781567 106354 89739254
Mental status changes 56.48 9.87 197 782642 44482 89801126
Exposure to toxic agent 56.42 9.87 3 782836 7964 89837644
Aspartate aminotransferase increased 56.00 9.87 593 782246 102344 89743264
Atrial fibrillation 56.00 9.87 814 782025 132797 89712811
Dizziness 55.57 9.87 4359 778480 584925 89260683
Hypomania 55.55 9.87 6 782833 8891 89836717
Angina pectoris 55.55 9.87 164 782675 38996 89806612
Nasal polyps 55.27 9.87 13 782826 10867 89834741
Psychotic disorder 55.04 9.87 117 782722 31113 89814495
Skin haemorrhage 55.02 9.87 62 782777 21318 89824290
Eating disorder 54.82 9.87 99 782740 27974 89817634
Carotid artery thrombosis 54.62 9.87 7 782832 9085 89836523
Dysgeusia 54.28 9.87 251 782588 52309 89793299
Basal cell carcinoma 53.97 9.87 482 782357 32907 89812701
Polyneuropathy 53.23 9.87 53 782786 19288 89826320
Paraesthesia oral 53.01 9.87 122 782717 31537 89814071
Hypomagnesaemia 52.72 9.87 146 782693 35442 89810166
Joint laxity 52.59 9.87 87 782752 2541 89843067
Joint stiffness 52.50 9.87 957 781882 77085 89768523
Respiratory distress 52.47 9.87 167 782672 38779 89806829
Ventricular fibrillation 52.26 9.87 28 782811 14016 89831592
Pulmonary oedema 52.11 9.87 318 782521 61762 89783846
Pain in jaw 52.05 9.87 225 782614 47760 89797848
Pancreatitis acute 51.98 9.87 126 782713 31989 89813619
Inappropriate antidiuretic hormone secretion 51.92 9.87 55 782784 19450 89826158
Dyskinesia 51.83 9.87 153 782686 36381 89809227
Swollen tongue 51.38 9.87 213 782626 45743 89799865
Headache 51.30 9.87 6599 776240 856147 88989461
Proteinuria 51.21 9.87 76 782763 23215 89822393
Alanine aminotransferase increased 50.98 9.87 717 782122 117621 89727987
Hepatotoxicity 50.93 9.87 213 782626 45629 89799979
Speech disorder 50.52 9.87 212 782627 45373 89800235
Gestational diabetes 50.39 9.87 203 782636 10379 89835229
Vaginal flatulence 50.35 9.87 23 782816 12615 89832993
Brain oedema 49.75 9.87 46 782793 17339 89828269
Second primary malignancy 49.65 9.87 14 782825 10364 89835244
Eczema 49.13 9.87 262 782577 52608 89793000
Bronchospasm 49.11 9.87 64 782775 20645 89824963
Myoclonus 48.87 9.87 56 782783 19112 89826496
Miosis 48.84 9.87 11 782828 9473 89836135
Arrhythmia 48.71 9.87 194 782645 42138 89803470
Acute respiratory failure 48.56 9.87 198 782641 42720 89802888
Face oedema 48.49 9.87 79 782760 23239 89822369
Toxic skin eruption 48.47 9.87 39 782800 15735 89829873
Status epilepticus 48.28 9.87 55 782784 18819 89826789
Haematotoxicity 48.12 9.87 24 782815 12511 89833097
Sleep disorder 48.00 9.87 2131 780708 195899 89649709
Stevens-Johnson syndrome 47.75 9.87 115 782724 29261 89816347
Prescribed underdose 47.72 9.87 912 781927 74107 89771501
Abnormal behaviour 47.68 9.87 76 782763 22552 89823056
Muscle spasticity 47.21 9.87 152 782687 35170 89810438
Acute generalised exanthematous pustulosis 47.19 9.87 30 782809 13673 89831935
Diabetes mellitus inadequate control 47.19 9.87 55 782784 18629 89826979
Loss of personal independence in daily activities 46.97 9.87 1523 781316 134582 89711026
Eye pruritus 46.89 9.87 114 782725 28913 89816695
Lower limb fracture 46.63 9.87 1011 781828 84002 89761606
Proctitis 46.55 9.87 38 782801 15221 89830387
Dystonia 46.39 9.87 46 782793 16773 89828835
Drug tolerance decreased 46.01 9.87 452 782387 31678 89813930
C-reactive protein 45.77 9.87 443 782396 30924 89814684
Haemorrhage 45.72 9.87 381 782458 68988 89776620
Lethargy 45.70 9.87 338 782501 62801 89782807
Coordination abnormal 45.69 9.87 71 782768 21285 89824323
Psoriasis 45.35 9.87 1631 781208 146123 89699485
Caesarean section 45.10 9.87 295 782544 18282 89827326
Pleural effusion 44.95 9.87 688 782151 111303 89734305
Osteoporosis 44.94 9.87 1122 781717 95409 89750199
Muscle twitching 44.92 9.87 88 782751 24114 89821494
Illness 44.67 9.87 472 782367 81497 89764111
Cytopenia 44.47 9.87 51 782788 17398 89828210
Gastrointestinal haemorrhage 44.33 9.87 532 782307 89716 89755892
Adjustment disorder 44.32 9.87 14 782825 9628 89835980
Rebound effect 44.27 9.87 13 782826 9371 89836237
Aggression 43.66 9.87 104 782735 26564 89819044
Irritability 43.25 9.87 160 782679 35502 89810106
Arterial occlusive disease 43.21 9.87 27 782812 12419 89833189
Multiple drug therapy 43.08 9.87 5 782834 7004 89838604
Haemophagocytic lymphohistiocytosis 42.96 9.87 42 782797 15417 89830191
Rhinitis allergic 42.84 9.87 49 782790 16736 89828872
Metastases to lung 42.67 9.87 45 782794 15946 89829662
Affect lability 42.65 9.87 56 782783 18007 89827601
Dry mouth 42.51 9.87 1971 780868 182088 89663520
Transplant rejection 42.49 9.87 29 782810 12729 89832879
Anti-cyclic citrullinated peptide antibody 42.49 9.87 390 782449 26831 89818777
Injection site reaction 41.90 9.87 1067 781772 91013 89754595
Female genital tract fistula 41.57 9.87 56 782783 17812 89827796
X-ray abnormal 41.45 9.87 586 782253 44838 89800770
Lymphocyte count decreased 41.37 9.87 159 782680 34891 89810717
Myocarditis 41.35 9.87 35 782804 13771 89831837
Coagulopathy 41.25 9.87 87 782752 23202 89822406
Premature labour 41.18 9.87 226 782613 13150 89832458
Hyperlipidaemia 41.10 9.87 85 782754 22831 89822777
Bronchopulmonary aspergillosis 40.58 9.87 24 782815 11374 89834234
Cardiogenic shock 40.39 9.87 95 782744 24373 89821235
Blood pressure diastolic decreased 40.19 9.87 381 782458 26445 89819163
Motor dysfunction 40.13 9.87 65 782774 19165 89826443
Eosinophilia 40.11 9.87 120 782719 28413 89817195
Fall 40.10 9.87 3599 779240 478211 89367397
Hypothyroidism 40.10 9.87 281 782558 52846 89792762
Obstructive airways disorder 39.92 9.87 104 782735 25765 89819843
Small for dates baby 39.74 9.87 114 782725 4893 89840715
Mania 39.68 9.87 38 782801 14086 89831522
Muscle rigidity 39.62 9.87 39 782800 14270 89831338
Cerebral infarction 39.48 9.87 109 782730 26487 89819121
Sinus tachycardia 39.30 9.87 121 782718 28392 89817216
Tachypnoea 39.10 9.87 78 782761 21231 89824377
Chills 39.09 9.87 855 781984 131126 89714482
Oedema 39.04 9.87 2110 780729 198185 89647423
Tardive dyskinesia 38.94 9.87 23 782816 10907 89834701
Atrioventricular block complete 38.86 9.87 18 782821 9793 89835815
Forced expiratory volume decreased 38.72 9.87 3 782836 5805 89839803
Laryngitis 38.69 9.87 635 782204 50118 89795490
Drug dose omission by device 38.66 9.87 20 782819 10211 89835397
Abdominal pain 38.37 9.87 2920 779919 392801 89452807
Lupus-like syndrome 38.30 9.87 614 782225 48232 89797376
Disability 38.13 9.87 528 782311 40217 89805391
Nodule 38.01 9.87 375 782464 26311 89819297
Neck deformity 37.94 9.87 68 782771 2121 89843487
Hospitalisation 37.90 9.87 830 782009 127270 89718338
Sensory loss 37.81 9.87 61 782778 18014 89827594
Nightmare 37.78 9.87 82 782757 21643 89823965
Tumour lysis syndrome 37.61 9.87 25 782814 11127 89834481
Acute myeloid leukaemia 37.49 9.87 76 782763 20564 89825044
Stress cardiomyopathy 37.44 9.87 36 782803 13319 89832289
Pain in extremity 37.40 9.87 4442 778397 446087 89399521
Radiculopathy 37.27 9.87 64 782775 18441 89827167
Graft versus host disease 37.13 9.87 12 782827 8132 89837476
Joint dislocation 37.09 9.87 566 782273 44016 89801592
Asphyxia 37.06 9.87 8 782831 7095 89838513
Dyspnoea exertional 36.71 9.87 423 782416 71865 89773743
Mental disorder 36.62 9.87 149 782690 32169 89813439
Hypoaesthesia 36.60 9.87 3171 779668 311039 89534569
Clostridium difficile colitis 36.34 9.87 114 782725 26592 89819016
Pulmonary arterial hypertension 36.19 9.87 111 782728 26076 89819532
Deep vein thrombosis 36.04 9.87 565 782274 91055 89754553
Haematoma 36.01 9.87 194 782645 38854 89806754
Vaginal discharge 35.93 9.87 71 782768 19393 89826215
Haemorrhage intracranial 35.81 9.87 47 782792 15115 89830493
Paradoxical drug reaction 35.72 9.87 4 782835 5762 89839846
Neuroleptic malignant syndrome 35.44 9.87 47 782792 15049 89830559
Melaena 35.44 9.87 167 782672 34630 89810978
Tuberculosis 35.32 9.87 207 782632 12342 89833266
Onychomycosis 35.24 9.87 485 782354 36891 89808717
Diabetes mellitus 35.17 9.87 374 782465 64501 89781107
Tinnitus 35.03 9.87 223 782616 42879 89802729
Lupus vulgaris 34.81 9.87 565 782274 44494 89801114
Hallucination, visual 34.75 9.87 94 782745 22998 89822610
Paralysis 34.50 9.87 29 782810 11449 89834159
Jaundice 34.34 9.87 154 782685 32363 89813245
Aspergillus infection 34.22 9.87 26 782813 10797 89834811
Device use error 34.07 9.87 10 782829 7211 89838397
Urinary retention 33.99 9.87 189 782650 37555 89808053
International normalised ratio increased 33.91 9.87 254 782585 47062 89798546
Haemoptysis 33.88 9.87 160 782679 33160 89812448
Rheumatoid nodule 33.57 9.87 293 782546 19873 89825735
Lung disorder 33.53 9.87 1600 781239 148283 89697325
Hepatic cytolysis 33.51 9.87 145 782694 30771 89814837
Gangrene 33.50 9.87 37 782802 12839 89832769
Mucosal inflammation 33.39 9.87 327 782512 57298 89788310
Acute graft versus host disease 33.36 9.87 4 782835 5464 89840144
Wheelchair user 32.90 9.87 144 782695 7641 89837967
Substance abuse 32.87 9.87 4 782835 5402 89840206
Panic attack 32.82 9.87 117 782722 26248 89819360
Epistaxis 32.80 9.87 527 782312 84598 89761010
Hepatic cirrhosis 32.72 9.87 746 782093 62507 89783101
Heart rate decreased 32.52 9.87 646 782193 52859 89792749
Haematochezia 32.21 9.87 425 782414 70488 89775120
Pseudomonas infection 32.20 9.87 49 782790 14816 89830792
Infective pulmonary exacerbation of cystic fibrosis 32.11 9.87 25 782814 10254 89835354
Product preparation error 32.00 9.87 25 782814 10236 89835372
Multiple fractures 31.78 9.87 165 782674 9397 89836211
Lip swelling 31.76 9.87 199 782640 38411 89807197
Device related infection 31.72 9.87 115 782724 25671 89819937
Skin burning sensation 31.69 9.87 77 782762 19534 89826074
Bradyphrenia 31.68 9.87 13 782826 7599 89838009
Cardiotoxicity 31.58 9.87 31 782808 11358 89834250
Retinitis 31.51 9.87 487 782352 37971 89807637
Exostosis 31.45 9.87 639 782200 52495 89793113
Circulatory collapse 31.35 9.87 110 782729 24794 89820814
Maternal drugs affecting foetus 31.34 9.87 107 782732 5048 89840560
Onychomadesis 31.26 9.87 565 782274 45433 89800175
Epstein-Barr virus infection 31.26 9.87 26 782813 10318 89835290
Swelling face 31.22 9.87 504 782335 80848 89764760
Multiple-drug resistance 31.22 9.87 14 782825 7762 89837846
Inappropriate schedule of product administration 31.11 9.87 1022 781817 148911 89696697
Erythema multiforme 30.98 9.87 36 782803 12210 89833398
Maternal exposure before pregnancy 30.94 9.87 184 782655 11029 89834579
Complication of device removal 30.75 9.87 8 782831 6247 89839361
Infusion site pain 30.73 9.87 79 782760 19659 89825949
Ischaemic stroke 30.60 9.87 94 782745 22072 89823536
Tenderness 30.58 9.87 361 782478 26507 89819101
Dysuria 30.43 9.87 207 782632 39194 89806414
Sleep apnoea syndrome 30.24 9.87 156 782683 31591 89814017
Acute graft versus host disease in skin 30.23 9.87 3 782836 4753 89840855
Acute respiratory distress syndrome 30.21 9.87 136 782703 28550 89817058
Ventricular septal defect 30.08 9.87 109 782730 5298 89840310
Psychomotor hyperactivity 29.97 9.87 40 782799 12773 89832835
Nervousness 29.87 9.87 172 782667 33884 89811724
Cardiomyopathy 29.85 9.87 83 782756 20123 89825485
Accidental overdose 29.80 9.87 134 782705 28139 89817469
Pericardial effusion 29.71 9.87 191 782648 36642 89808966
Leukocytosis 29.67 9.87 152 782687 30838 89814770
Oral candidiasis 29.55 9.87 182 782657 35273 89810335
Lymphopenia 29.52 9.87 100 782739 22781 89822827
Jaundice cholestatic 29.42 9.87 26 782813 10017 89835591
Complication of device insertion 29.41 9.87 28 782811 10408 89835200
Glycosylated haemoglobin increased 29.39 9.87 56 782783 15506 89830102
Crying 29.21 9.87 118 782721 25527 89820081
Immune reconstitution inflammatory syndrome 29.19 9.87 12 782827 7007 89838601
Febrile bone marrow aplasia 28.79 9.87 25 782814 9713 89835895
Product prescribing error 28.78 9.87 148 782691 29997 89815611
Rash maculo-papular 28.73 9.87 221 782618 40712 89804896
Genital haemorrhage 28.69 9.87 20 782819 8682 89836926
Product administration error 28.59 9.87 124 782715 26299 89819309
Influenza like illness 28.47 9.87 507 782332 80104 89765504
Premature rupture of membranes 28.39 9.87 109 782730 5449 89840159
Hot flush 28.33 9.87 353 782486 59135 89786473
Aspiration 28.32 9.87 58 782781 15635 89829973
Vascular device infection 28.28 9.87 37 782802 11915 89833693
Drug hypersensitivity 28.20 9.87 3540 779299 460069 89385539
Product prescribing issue 28.13 9.87 17 782822 7962 89837646
Fear 27.87 9.87 64 782775 16558 89829050
Ketoacidosis 27.81 9.87 7 782832 5588 89840020
Interstitial lung disease 27.80 9.87 478 782361 75927 89769681
Pathogen resistance 27.63 9.87 18 782821 8097 89837511
Device dislocation 27.62 9.87 159 782680 31323 89814285
Pulmonary hypertension 27.37 9.87 235 782604 42288 89803320
Pyrexia 27.32 9.87 5158 777681 655327 89190281
Dysphonia 27.24 9.87 382 782457 62702 89782906
Hypophagia 27.16 9.87 190 782649 35747 89809861
Toxic epidermal necrolysis 27.10 9.87 167 782672 32361 89813247
Sinus disorder 27.09 9.87 180 782659 34267 89811341
Product administered to patient of inappropriate age 26.96 9.87 4 782835 4649 89840959
Pemphigoid 26.89 9.87 23 782816 9003 89836605
Delusion 26.85 9.87 49 782790 13791 89831817
Wheezing 26.82 9.87 2397 780442 235683 89609925
Urinary incontinence 26.76 9.87 202 782637 37364 89808244
Hypophosphataemia 26.72 9.87 55 782784 14799 89830809
Blood pressure diastolic increased 26.65 9.87 197 782642 12709 89832899
Blood urea increased 26.46 9.87 154 782685 30259 89815349
Respiratory acidosis 26.32 9.87 19 782820 8100 89837508
Myopathy 26.10 9.87 48 782791 13470 89832138
Transaminases increased 26.01 9.87 201 782638 36991 89808617
Dysmorphism 26.00 9.87 64 782775 2504 89843104
Eye irritation 25.99 9.87 179 782660 33799 89811809
Blood potassium decreased 25.93 9.87 275 782564 47452 89798156
Incorrect dose administered 25.83 9.87 503 782336 78427 89767181
Body temperature decreased 25.79 9.87 317 782522 23499 89822109
Enthesopathy 25.74 9.87 154 782685 9250 89836358
Acute chest syndrome 25.71 9.87 40 782799 1108 89844500
Cytomegalovirus infection reactivation 25.62 9.87 18 782821 7782 89837826
Hyperbilirubinaemia 25.58 9.87 51 782788 13885 89831723
Sinus bradycardia 25.52 9.87 69 782770 16883 89828725
Purpura 25.51 9.87 56 782783 14722 89830886
Subarachnoid haemorrhage 25.38 9.87 75 782764 17829 89827779
Blood glucose decreased 25.32 9.87 110 782729 23319 89822289
Limb deformity 25.08 9.87 86 782753 4066 89841542
Graft versus host disease in gastrointestinal tract 24.91 9.87 4 782835 4384 89841224
Anuria 24.89 9.87 57 782782 14761 89830847
Hypervolaemia 24.85 9.87 173 782666 32584 89813024
Acidosis 24.79 9.87 45 782794 12691 89832917
Breast cancer metastatic 24.78 9.87 59 782780 15073 89830535
Eosinophil count increased 24.77 9.87 47 782792 13034 89832574
Heart rate increased 24.76 9.87 764 782075 112138 89733470
Right ventricular failure 24.73 9.87 84 782755 19121 89826487
Ankylosing spondylitis 24.62 9.87 196 782643 12937 89832671
Middle insomnia 24.60 9.87 69 782770 16682 89828926
Bradykinesia 24.58 9.87 14 782825 6774 89838834
Labelled drug-drug interaction medication error 24.57 9.87 56 782783 14526 89831082
Renal tubular necrosis 24.44 9.87 56 782783 14499 89831109
Device breakage 24.43 9.87 53 782786 13991 89831617
Smear cervix abnormal 24.42 9.87 71 782768 3071 89842537
Seronegative arthritis 24.42 9.87 253 782586 17981 89827627
Ileus 24.42 9.87 68 782771 16478 89829130
Pulmonary congestion 24.35 9.87 86 782753 19347 89826261
Maternal exposure timing unspecified 24.24 9.87 299 782540 22184 89823424
Multiple sclerosis 24.21 9.87 141 782698 27699 89817909
Colitis microscopic 23.97 9.87 37 782802 11122 89834486
Atrial septal defect 23.94 9.87 137 782702 8097 89837511
Blepharospasm 23.92 9.87 638 782201 54807 89790801
Paranoia 23.90 9.87 47 782792 12861 89832747
Sexual dysfunction 23.89 9.87 6 782833 4798 89840810
Treatment noncompliance 23.87 9.87 309 782530 51418 89794190
Latent tuberculosis 23.86 9.87 68 782771 2908 89842700
Lymphoedema 23.84 9.87 52 782787 13701 89831907
Polyuria 23.84 9.87 31 782808 10009 89835599
Drug effective for unapproved indication 23.81 9.87 20 782819 7898 89837710
Toxic encephalopathy 23.75 9.87 24 782815 8675 89836933
Atrial tachycardia 23.71 9.87 11 782828 5979 89839629
Malignant mediastinal neoplasm 23.47 9.87 43 782796 1365 89844243
Mood altered 23.46 9.87 73 782766 17071 89828537
Rales 23.39 9.87 65 782774 15762 89829846
Ear infection 23.35 9.87 778 782061 68997 89776611
Multiple allergies 23.29 9.87 61 782778 15085 89830523
Pallor 23.26 9.87 186 782653 33979 89811629
Glomerular filtration rate decreased 23.23 9.87 72 782767 16860 89828748
Presyncope 23.14 9.87 170 782669 31635 89813973
Pulseless electrical activity 22.88 9.87 26 782813 8906 89836702
Breast cancer female 22.85 9.87 60 782779 14826 89830782
Bradypnoea 22.82 9.87 6 782833 4652 89840956
Systemic inflammatory response syndrome 22.81 9.87 14 782825 6502 89839106
Electrocardiogram QRS complex prolonged 22.79 9.87 18 782821 7330 89838278
Schizoaffective disorder 22.74 9.87 8 782831 5139 89840469
Bacteraemia 22.72 9.87 107 782732 22193 89823415
Dissociation 22.72 9.87 15 782824 6700 89838908
Subdural haematoma 22.68 9.87 71 782768 16574 89829034
Antinuclear antibody positive 22.59 9.87 147 782692 9094 89836514
Cyanosis 22.48 9.87 89 782750 19366 89826242
Complication associated with device 22.46 9.87 89 782750 19360 89826248
Prescribed overdose 22.43 9.87 1045 781794 96580 89749028
Acute myocardial infarction 22.37 9.87 193 782646 34697 89810911
Drug tolerance 22.32 9.87 245 782594 17671 89827937
Acute pulmonary oedema 22.31 9.87 30 782809 9550 89836058
Agranulocytosis 22.27 9.87 194 782645 34808 89810800
Pulmonary alveolar haemorrhage 22.26 9.87 12 782827 5986 89839622
Rheumatoid lung 22.23 9.87 82 782757 4021 89841587
Tubulointerstitial nephritis 22.23 9.87 128 782711 25215 89820393
Chronic obstructive pulmonary disease 22.23 9.87 477 782362 73352 89772256
Throat tightness 22.22 9.87 156 782683 29328 89816280
Atrioventricular block 22.21 9.87 26 782813 8789 89836819
Metastases to lymph nodes 22.13 9.87 42 782797 11647 89833961
Generalised oedema 22.12 9.87 87 782752 18966 89826642
Oliguria 22.08 9.87 36 782803 10588 89835020
Head injury 22.07 9.87 168 782671 31020 89814588
Blood lactic acid increased 22.00 9.87 26 782813 8752 89836856
Finger deformity 21.98 9.87 403 782436 32494 89813114
Skin toxicity 21.80 9.87 16 782823 6763 89838845
Cytomegalovirus viraemia 21.79 9.87 20 782819 7566 89838042
Respiration abnormal 21.71 9.87 22 782817 7941 89837667
Rotator cuff repair 21.58 9.87 58 782781 2396 89843212
Hyperuricaemia 21.42 9.87 16 782823 6703 89838905
Gastroenteritis viral 21.39 9.87 375 782464 29980 89815628
Localised infection 21.33 9.87 408 782431 33154 89812454
Hypernatraemia 21.26 9.87 30 782809 9357 89836251
Sneezing 21.09 9.87 161 782678 29708 89815900
Insurance issue 21.08 9.87 39 782800 10919 89834689
Product adhesion issue 21.05 9.87 9 782830 5133 89840475
Product administration interrupted 21.03 9.87 48 782791 12444 89833164
Synovial disorder 20.99 9.87 67 782772 3051 89842557
Chronic graft versus host disease 20.92 9.87 5 782834 4134 89841474
Body height below normal 20.87 9.87 53 782786 2115 89843493
Adenovirus infection 20.74 9.87 7 782832 4615 89840993
Hepatitis acute 20.72 9.87 39 782800 10848 89834760
Respiratory tract congestion 20.67 9.87 145 782694 27265 89818343
Tenosynovitis stenosans 20.58 9.87 78 782761 3875 89841733
Placental disorder 20.57 9.87 44 782795 1567 89844041
Device issue 20.48 9.87 160 782679 29377 89816231
Transplant dysfunction 20.45 9.87 10 782829 5272 89840336
Therapeutic response shortened 20.36 9.87 115 782724 22764 89822844
Synovial fluid analysis 20.31 9.87 62 782777 2756 89842852
Total lung capacity increased 20.22 9.87 9 782830 5012 89840596
Hallucinations, mixed 20.13 9.87 13 782826 5876 89839732
Product storage error 20.11 9.87 98 782741 20143 89825465
Sputum discoloured 20.10 9.87 99 782740 20292 89825316
Therapy interrupted 20.04 9.87 308 782531 49800 89795808
Urinary tract infection 20.04 9.87 2322 780517 303310 89542298
Troponin increased 20.03 9.87 54 782785 13227 89832381
Hyperprolactinaemia 19.97 9.87 11 782828 5422 89840186
Blood test abnormal 19.93 9.87 103 782736 20849 89824759
Developmental hip dysplasia 19.90 9.87 43 782796 1542 89844066
Bone marrow failure 19.88 9.87 180 782659 32041 89813567
Nail operation 19.83 9.87 48 782791 1858 89843750
Hallucination, auditory 19.81 9.87 71 782768 15904 89829704
Systemic candida 19.80 9.87 9 782830 4950 89840658
Clostridium test positive 19.76 9.87 11 782828 5390 89840218
Device leakage 19.72 9.87 35 782804 9956 89835652
Salivary hypersecretion 19.67 9.87 30 782809 9062 89836546
Dementia 19.62 9.87 123 782716 23738 89821870
Sleep terror 19.62 9.87 7 782832 4457 89841151
Infusion site erythema 19.57 9.87 57 782782 13613 89831995
Red blood cell sedimentation rate 19.56 9.87 86 782753 4572 89841036
Abdominal distension 19.52 9.87 925 781914 129676 89715932
Acute coronary syndrome 19.48 9.87 40 782799 10773 89834835
Walking aid user 19.39 9.87 422 782417 35084 89810524
Impaired gastric emptying 19.38 9.87 52 782787 12757 89832851
Night sweats 19.36 9.87 1326 781513 127440 89718168
Immune effector cell-associated neurotoxicity syndrome 19.36 9.87 13 782826 5755 89839853
Stillbirth 19.18 9.87 120 782719 7323 89838285
Laryngospasm 19.01 9.87 3 782836 3330 89842278
Injection site pruritus 18.98 9.87 604 782235 53230 89792378
Neck mass 18.91 9.87 75 782764 3807 89841801
Blindness 18.85 9.87 143 782696 26425 89819183
Loose body in joint 18.72 9.87 39 782800 1363 89844245
Electrolyte imbalance 18.71 9.87 124 782715 23621 89821987
Therapy non-responder 18.71 9.87 1397 781442 135307 89710301
Foetal anticonvulsant syndrome 18.64 9.87 26 782813 651 89844957
Klebsiella infection 18.63 9.87 38 782801 10259 89835349
Visual acuity reduced 18.57 9.87 122 782717 23288 89822320
Affective disorder 18.56 9.87 24 782815 7769 89837839
Body temperature increased 18.51 9.87 273 782566 44437 89801171
Progressive multifocal leukoencephalopathy 18.49 9.87 71 782768 15584 89830024
Bone lesion 18.46 9.87 17 782822 6420 89839188
Post-traumatic stress disorder 18.46 9.87 19 782820 6809 89838799
Cardiac disorder 18.44 9.87 363 782476 56509 89789099
Plasma cell myeloma 18.43 9.87 245 782594 40583 89805025
Immune-mediated enterocolitis 18.42 9.87 9 782830 4748 89840860
Blood pressure inadequately controlled 18.37 9.87 16 782823 6208 89839400
Renal injury 18.36 9.87 38 782801 10205 89835403
Diplopia 18.34 9.87 159 782680 28555 89817053
Shock haemorrhagic 18.31 9.87 50 782789 12195 89833413
Hereditary angioedema 18.31 9.87 33 782806 9332 89836276
Tumour marker increased 18.30 9.87 14 782825 5793 89839815
Lacrimation increased 18.12 9.87 148 782691 26914 89818694
Nail disorder 18.11 9.87 652 782187 58415 89787193
Diabetes insipidus 18.07 9.87 3 782836 3209 89842399
Bundle branch block left 18.06 9.87 25 782814 7860 89837748
Spinal stenosis 18.05 9.87 230 782609 17194 89828414
Rhinovirus infection 18.00 9.87 15 782824 5948 89839660
Anti-neutrophil cytoplasmic antibody positive vasculitis 18.00 9.87 6 782833 3987 89841621
Renal disorder 17.90 9.87 225 782614 37634 89807974
Hepatitis B reactivation 17.86 9.87 6 782833 3968 89841640
End stage renal disease 17.86 9.87 29 782810 8542 89837066
Cleft lip and palate 17.85 9.87 27 782812 729 89844879
Postoperative wound infection 17.84 9.87 186 782653 13240 89832368
Asthma 17.83 9.87 1825 781014 240335 89605273
Generalised tonic-clonic seizure 17.81 9.87 204 782635 34699 89810909
Pulmonary haemorrhage 17.76 9.87 26 782813 7987 89837621
Blood lactate dehydrogenase increased 17.74 9.87 141 782698 25791 89819817
Injection site erythema 17.68 9.87 1030 781809 97472 89748136
Cholelithiasis 17.67 9.87 333 782506 52173 89793435
Haematemesis 17.65 9.87 196 782643 33530 89812078
Pre-eclampsia 17.60 9.87 159 782680 10889 89834719
Nystagmus 17.48 9.87 22 782817 7205 89838403
Ankle arthroplasty 17.42 9.87 59 782780 2772 89842836
Bundle branch block right 17.37 9.87 13 782826 5440 89840168
Blood phosphorus decreased 17.37 9.87 11 782828 5023 89840585
Coronary artery disease 17.36 9.87 196 782643 33427 89812181
Temperature intolerance 17.34 9.87 50 782789 11980 89833628
Hyperlactacidaemia 17.32 9.87 7 782832 4129 89841479
Anosmia 17.27 9.87 37 782802 9811 89835797
Hyperthermia 17.16 9.87 40 782799 10295 89835313
Synovial cyst 17.16 9.87 166 782673 11586 89834022
Amyloid arthropathy 17.15 9.87 42 782797 1638 89843970
Tenosynovitis 17.14 9.87 197 782642 14370 89831238
Enterocolitis 17.10 9.87 41 782798 10449 89835159
Pruritus genital 17.09 9.87 9 782830 4549 89841059
Euglycaemic diabetic ketoacidosis 17.05 9.87 17 782822 6184 89839424
Hypoalbuminaemia 16.96 9.87 75 782764 15822 89829786
Pharyngeal swelling 16.91 9.87 38 782801 9906 89835702
Pseudomonal sepsis 16.87 9.87 8 782831 4294 89841314
Anhedonia 16.85 9.87 47 782792 11384 89834224
Malaise 16.82 9.87 4656 778183 581330 89264278
Haemodynamic instability 16.77 9.87 49 782790 11690 89833918
Feeding disorder 16.71 9.87 86 782753 17426 89828182
Product dose omission in error 16.70 9.87 106 782733 20397 89825211
Dermatitis exfoliative 16.62 9.87 14 782825 5522 89840086
Human antichimeric antibody positive 16.51 9.87 43 782796 1743 89843865
Thrombosis 16.47 9.87 494 782345 72757 89772851
Antibody test positive 16.41 9.87 60 782779 2929 89842679
Hypogammaglobulinaemia 16.40 9.87 43 782796 10631 89834977
Hypoglycaemic coma 16.37 9.87 3 782836 2987 89842621
Ventricular extrasystoles 16.36 9.87 59 782780 13191 89832417
Hyperthyroidism 16.32 9.87 92 782747 18218 89827390
Hepatic necrosis 16.21 9.87 19 782820 6419 89839189
Potentiating drug interaction 16.18 9.87 15 782824 5647 89839961
Cardiac failure acute 16.18 9.87 51 782788 11878 89833730
Congenital arterial malformation 16.17 9.87 17 782822 314 89845294
Malignant melanoma 16.14 9.87 173 782666 12403 89833205
Peripheral sensory neuropathy 16.01 9.87 35 782804 9215 89836393
Personality change 15.99 9.87 24 782815 7297 89838311
Septic shock 15.99 9.87 580 782259 83580 89762028
Femur fracture 15.98 9.87 516 782323 45566 89800042
Infusion site swelling 15.97 9.87 50 782789 11670 89833938
Infusion site pruritus 15.95 9.87 21 782818 6744 89838864
Type 1 diabetes mellitus 15.94 9.87 11 782828 4801 89840807
Arthritis infective 15.94 9.87 121 782718 7871 89837737
Spondylitis 15.91 9.87 190 782649 13988 89831620
Pain of skin 15.90 9.87 78 782761 16004 89829604
Liver disorder 15.88 9.87 1235 781604 120034 89725574
Skin lesion 15.87 9.87 227 782612 37138 89808470
Pneumatosis intestinalis 15.78 9.87 5 782834 3432 89842176
Staphylococcal infection 15.75 9.87 309 782530 48130 89797478
Dermatitis acneiform 15.73 9.87 19 782820 6335 89839273
Trigeminal neuralgia 15.72 9.87 8 782831 4123 89841485
Neutrophilia 15.71 9.87 16 782823 5762 89839846
Catheter site pain 15.69 9.87 15 782824 5564 89840044
Limb reduction defect 15.65 9.87 23 782816 605 89845003
Amylase increased 15.62 9.87 23 782816 7049 89838559
Clear cell renal cell carcinoma 15.60 9.87 39 782800 1541 89844067
Pneumonia viral 15.59 9.87 33 782806 8790 89836818
Laryngeal oedema 15.57 9.87 22 782817 6859 89838749
Facial paralysis 15.56 9.87 75 782764 15459 89830149
Pneumonitis 15.53 9.87 278 782561 43892 89801716
Skin plaque 15.47 9.87 40 782799 9935 89835673
Lymphatic fistula 15.42 9.87 37 782802 1424 89844184
Extra dose administered 15.37 9.87 35 782804 9083 89836525
Scleritis 15.37 9.87 87 782752 5121 89840487
Neuralgia 15.34 9.87 186 782653 31314 89814294
Maternal exposure during delivery 15.32 9.87 7 782832 3839 89841769
Skin papilloma 15.28 9.87 92 782747 5538 89840070
Polyhydramnios 15.20 9.87 52 782787 2456 89843152
Candida infection 15.14 9.87 205 782634 33852 89811756
Hypertelorism 15.14 9.87 21 782818 523 89845085
Ileus paralytic 15.10 9.87 13 782826 5072 89840536
Rash macular 15.05 9.87 178 782661 30102 89815506
Nasal oedema 15.05 9.87 103 782736 6481 89839127
Activated partial thromboplastin time prolonged 14.92 9.87 28 782811 7797 89837811
Unevaluable event 14.92 9.87 360 782479 54488 89791120
Device malfunction 14.84 9.87 113 782726 20864 89824744
Nasal obstruction 14.83 9.87 53 782786 2559 89843049
Breast feeding 14.76 9.87 27 782812 856 89844752
Device physical property issue 14.74 9.87 3 782836 2773 89842835
Product substitution issue 14.72 9.87 93 782746 17915 89827693
Nephropathy toxic 14.69 9.87 58 782781 12630 89832978
Erythema of eyelid 14.68 9.87 5 782834 3278 89842330
Sleep disorder due to a general medical condition 14.67 9.87 285 782554 44453 89801155
Femoral hernia incarcerated 14.65 9.87 37 782802 1471 89844137
Retrognathia 14.55 9.87 21 782818 543 89845065
Rectal haemorrhage 14.44 9.87 576 782263 82168 89763440
Bezoar 14.43 9.87 3 782836 2731 89842877
Hyperammonaemia 14.36 9.87 21 782818 6454 89839154
Hyperpyrexia 14.35 9.87 12 782827 4749 89840859
Loss of employment 14.35 9.87 4 782835 2983 89842625
Lung opacity 14.32 9.87 19 782820 6083 89839525
Reversible cerebral vasoconstriction syndrome 14.28 9.87 9 782830 4121 89841487
Intracranial pressure increased 14.23 9.87 23 782816 6788 89838820
Haematuria 14.23 9.87 214 782625 34723 89810885
Bone density increased 14.20 9.87 27 782812 882 89844726
Pneumothorax 14.16 9.87 102 782737 19065 89826543
Immune thrombocytopenia 14.14 9.87 63 782776 13263 89832345
Back injury 14.14 9.87 514 782325 46108 89799500
Wound infection pseudomonas 14.11 9.87 44 782795 1979 89843629
Varicella zoster virus infection 14.04 9.87 8 782831 3869 89841739
Hypoventilation 14.02 9.87 15 782824 5281 89840327
Skin ulcer 13.97 9.87 547 782292 49528 89796080
Confusional state 13.95 9.87 3645 779194 382560 89463048
Epstein-Barr virus associated lymphoproliferative disorder 13.92 9.87 3 782836 2664 89842944
Haemorrhage in pregnancy 13.85 9.87 46 782793 2139 89843469
Ulcer haemorrhage 13.79 9.87 311 782528 26010 89819598
Kidney transplant rejection 13.72 9.87 13 782826 4844 89840764
Mouth ulceration 13.70 9.87 447 782392 39527 89806081
Long QT syndrome 13.68 9.87 9 782830 4028 89841580
Abortion incomplete 13.67 9.87 5 782834 3135 89842473
Restless legs syndrome 13.66 9.87 126 782713 22344 89823264
Crohn's disease 13.64 9.87 80 782759 4771 89840837
Brain injury 13.63 9.87 29 782810 7709 89837899
Polydipsia 13.59 9.87 10 782829 4221 89841387
Exercise tolerance decreased 13.55 9.87 28 782811 7523 89838085
Impaired quality of life 13.55 9.87 131 782708 23013 89822595
Hepatitis cholestatic 13.53 9.87 34 782805 8527 89837081
Metastasis 13.52 9.87 20 782819 6117 89839491
Fracture delayed union 13.51 9.87 50 782789 2456 89843152
Speech disorder developmental 13.50 9.87 27 782812 916 89844692
Increased appetite 13.48 9.87 54 782785 11711 89833897
Blood sodium decreased 13.47 9.87 163 782676 27450 89818158
Feeling hot 13.41 9.87 544 782295 77464 89768144
Short stature 13.40 9.87 29 782810 1041 89844567
Hypokinesia 13.38 9.87 80 782759 15617 89829991
Ataxia 13.33 9.87 96 782743 17946 89827662
Cholecystitis chronic 13.33 9.87 42 782797 9784 89835824
Amenorrhoea 13.31 9.87 54 782785 11668 89833940
Choking 13.31 9.87 56 782783 11977 89833631
Incoherent 13.28 9.87 14 782825 4963 89840645
Pneumonia bacterial 13.25 9.87 61 782778 12729 89832879
Iritis 13.23 9.87 65 782774 3621 89841987
Atrial flutter 13.22 9.87 48 782791 10710 89834898
Nocardiosis 13.20 9.87 3 782836 2567 89843041
Hepatitis fulminant 13.09 9.87 9 782830 3936 89841672
Pancreatitis 13.08 9.87 482 782357 69344 89776264
Central nervous system lesion 13.00 9.87 54 782785 11592 89834016
Skin weeping 12.99 9.87 4 782835 2796 89842812
Full blood count abnormal 12.98 9.87 230 782609 36367 89809241
Device use issue 12.96 9.87 8 782831 3705 89841903
Gastroschisis 12.95 9.87 17 782822 401 89845207
Hepatic encephalopathy 12.93 9.87 68 782771 13704 89831904
Eosinophilic granulomatosis with polyangiitis 12.90 9.87 3 782836 2527 89843081
Neoplasm recurrence 12.88 9.87 6 782833 3253 89842355
Nail injury 12.83 9.87 24 782815 774 89844834
Carotid artery occlusion 12.71 9.87 22 782817 6320 89839288
Endophthalmitis 12.71 9.87 13 782826 4672 89840936
Product residue present 12.70 9.87 11 782828 4280 89841328
Pregnancy with contraceptive device 12.70 9.87 15 782824 5051 89840557
Dyspepsia 12.68 9.87 1924 780915 196236 89649372
Hypercapnia 12.63 9.87 24 782815 6653 89838955
Congenital anomaly 12.61 9.87 96 782743 6251 89839357
Eyelid oedema 12.56 9.87 54 782785 11480 89834128
Myocardial ischaemia 12.53 9.87 69 782770 13745 89831863
Atrioventricular block second degree 12.48 9.87 12 782827 4440 89841168
Cushingoid 12.42 9.87 141 782698 10254 89835354
Needle issue 12.42 9.87 70 782769 13864 89831744
Thirst 12.39 9.87 86 782753 16209 89829399
Eye swelling 12.31 9.87 179 782660 29207 89816401
Anger 12.19 9.87 69 782770 13651 89831957
Lipase increased 12.11 9.87 52 782787 11059 89834549
Cystitis haemorrhagic 12.11 9.87 18 782821 5495 89840113
Adverse drug reaction 12.08 9.87 1168 781671 115533 89730075
Disturbance in social behaviour 12.08 9.87 11 782828 4177 89841431
Intervertebral disc degeneration 12.03 9.87 213 782626 17061 89828547
Product availability issue 12.02 9.87 29 782810 7375 89838233
Uterine perforation 11.94 9.87 30 782809 7524 89838084
Inflammatory marker increased 11.94 9.87 127 782712 9087 89836521
Pathological fracture 11.94 9.87 43 782796 9617 89835991
Product physical issue 11.93 9.87 19 782820 5641 89839967
Benign ovarian tumour 11.93 9.87 18 782821 485 89845123
Osteolysis 11.92 9.87 8 782831 3542 89842066
Blood potassium increased 11.91 9.87 118 782721 20631 89824977
Metastases to peritoneum 11.88 9.87 11 782828 4144 89841464
Ingrown hair 11.83 9.87 20 782819 595 89845013
Device deployment issue 11.82 9.87 15 782824 4894 89840714
Cholangitis 11.76 9.87 28 782811 7154 89838454
International normalised ratio fluctuation 11.76 9.87 6 782833 3087 89842521
Dermatitis contact 11.74 9.87 69 782770 13526 89832082
Catheter site erythema 11.73 9.87 15 782824 4879 89840729
Pancreatic steatosis 11.72 9.87 36 782803 1606 89844002
Cross sensitivity reaction 11.70 9.87 5 782834 2852 89842756
Dermatitis 11.68 9.87 129 782710 22091 89823517
Hyperreflexia 11.68 9.87 25 782814 6632 89838976
Skin fissures 11.67 9.87 119 782720 20690 89824918
Post procedural haemorrhage 11.66 9.87 38 782801 8760 89836848
Osteonecrosis 11.65 9.87 158 782681 26083 89819525
Implant site pain 11.64 9.87 4 782835 2608 89843000
Oligoarthritis 11.63 9.87 19 782820 549 89845059
Congenital cerebral cyst 11.63 9.87 13 782826 258 89845350
Exomphalos 11.61 9.87 19 782820 550 89845058
Immunosuppressant drug level increased 11.58 9.87 14 782825 4666 89840942
Metabolic disorder 11.55 9.87 30 782809 7440 89838168
Clostridium difficile infection 11.55 9.87 232 782607 36013 89809595
Hypotonia 11.54 9.87 55 782784 11371 89834237
Major depression 11.54 9.87 46 782793 9989 89835619
Cerebral haematoma 11.52 9.87 12 782827 4277 89841331
Lung transplant 11.51 9.87 9 782830 3683 89841925
Abnormal dreams 11.48 9.87 54 782785 11203 89834405
Cleft palate 11.47 9.87 31 782808 1285 89844323
Terminal state 11.43 9.87 5 782834 2813 89842795
Catheter site haemorrhage 11.36 9.87 9 782830 3659 89841949
Lip oedema 11.35 9.87 14 782825 4625 89840983
Intraocular pressure increased 11.34 9.87 28 782811 7065 89838543
Intestinal ischaemia 11.34 9.87 39 782800 8844 89836764
Blood loss anaemia 11.33 9.87 47 782792 10093 89835515
Hypertransaminasaemia 11.31 9.87 85 782754 15740 89829868
Pulmonary tuberculosis 11.27 9.87 76 782763 4758 89840850
Neutrophil count increased 11.24 9.87 110 782729 19280 89826328
Learning disorder 11.23 9.87 24 782815 854 89844754
Bacterial infection 11.20 9.87 139 782700 23305 89822303
Sickle cell anaemia 11.20 9.87 20 782819 622 89844986
Ventricular hypokinesia 11.19 9.87 18 782821 5323 89840285
Ageusia 11.19 9.87 87 782752 15989 89829619
Inadequate analgesia 11.18 9.87 7 782832 3217 89842391
Poor quality device used 11.15 9.87 3 782836 2290 89843318
Respiratory disorder 11.14 9.87 452 782387 64364 89781244
Human anti-human antibody test 11.14 9.87 16 782823 412 89845196
Therapeutic response unexpected 11.12 9.87 128 782711 21752 89823856
Persecutory delusion 11.08 9.87 7 782832 3201 89842407
Cervical incompetence 11.07 9.87 20 782819 628 89844980
Pneumonia fungal 11.05 9.87 28 782811 7003 89838605
Pneumonia aspiration 11.05 9.87 269 782570 40671 89804937
Heparin-induced thrombocytopenia 11.04 9.87 18 782821 5294 89840314
Tendonitis 11.03 9.87 252 782587 21120 89824488
Wrong technique in device usage process 11.02 9.87 21 782818 5814 89839794
Skin cancer 11.00 9.87 171 782668 13348 89832260
Cyst rupture 10.96 9.87 23 782816 808 89844800
Upper-airway cough syndrome 10.96 9.87 81 782758 15054 89830554
Cardiac failure chronic 10.94 9.87 20 782819 5626 89839982
Total lung capacity decreased 10.91 9.87 10 782829 3785 89841823
Blood parathyroid hormone decreased 10.91 9.87 157 782682 12059 89833549
Foetal distress syndrome 10.91 9.87 36 782803 1669 89843939
Pulmonary function test abnormal 10.89 9.87 5 782834 2734 89842874
Productive cough 10.89 9.87 549 782290 76514 89769094
Sensitisation 10.86 9.87 12 782827 4163 89841445
Flatulence 10.85 9.87 273 782566 41094 89804514
Subacute cutaneous lupus erythematosus 10.83 9.87 9 782830 3573 89842035
Micturition urgency 10.81 9.87 55 782784 11178 89834430
Pulmonary toxicity 10.79 9.87 57 782782 11474 89834134
Haemodialysis 10.77 9.87 39 782800 8708 89836900
Immune-mediated hepatitis 10.77 9.87 6 782833 2938 89842670
Type I hypersensitivity 10.74 9.87 12 782827 4143 89841465
Drug screen positive 10.68 9.87 10 782829 3747 89841861
Skin swelling 10.66 9.87 26 782813 6588 89839020
Retinal haemorrhage 10.66 9.87 21 782818 5743 89839865
Granuloma skin 10.65 9.87 140 782699 10540 89835068
Ventricular arrhythmia 10.61 9.87 13 782826 4308 89841300
Metastases to spine 10.60 9.87 10 782829 3733 89841875
Lymph gland infection 10.56 9.87 18 782821 539 89845069
Immunisation 10.56 9.87 3 782836 2210 89843398
Blood calcium increased 10.52 9.87 61 782778 11997 89833611
Mental impairment 10.49 9.87 93 782746 16627 89828981
Hypocalcaemia 10.47 9.87 282 782557 42086 89803522
Fracture 10.39 9.87 257 782582 21819 89823789
Device occlusion 10.39 9.87 43 782796 9239 89836369
Cold sweat 10.37 9.87 75 782764 14006 89831602
Hypoglycaemia neonatal 10.36 9.87 27 782812 1095 89844513
Paranasal sinus discomfort 10.34 9.87 24 782815 6186 89839422
Breast cancer stage II 10.34 9.87 388 782451 34946 89810662
Colorectal cancer 10.34 9.87 11 782828 3882 89841726
Talipes 10.33 9.87 35 782804 1645 89843963
Anal incontinence 10.31 9.87 90 782749 16140 89829468
Facial pain 10.30 9.87 69 782770 13113 89832495
Foot operation 10.27 9.87 121 782718 8880 89836728
Cholecystitis acute 10.26 9.87 44 782795 9360 89836248
Wrong product administered 10.23 9.87 33 782806 7632 89837976
Joint warmth 10.21 9.87 36 782803 1726 89843882
Formication 10.18 9.87 16 782823 4775 89840833
Oral pain 10.18 9.87 210 782629 32473 89813135
Staphylococcal sepsis 10.17 9.87 44 782795 9339 89836269
Injection site warmth 10.15 9.87 210 782629 17305 89828303
Decreased appetite 10.11 9.87 3000 779839 373540 89472068
Cell death 10.10 9.87 7 782832 3048 89842560
Hypochloraemia 10.10 9.87 5 782834 2617 89842991
Induced labour 10.08 9.87 25 782814 983 89844625
Cardiac tamponade 10.01 9.87 21 782818 5611 89839997
Depressive symptom 10.00 9.87 19 782820 5266 89840342
Skin disorder 9.96 9.87 241 782598 36465 89809143
Liver function test increased 9.96 9.87 857 781982 83998 89761610
Embolism 9.95 9.87 45 782794 9436 89836172
Congenital foot malformation 9.88 9.87 12 782827 261 89845347

FDA Adverse Event Reporting System (Male)

MedDRA adverse event termLikelihood ratioLikelihood ratio thresholdPatients taking drug having adverse eventPatients taking drug not having adverse eventPatients not taking drug having adverse eventPatients not taking drug not having adverse event
Rheumatoid arthritis 660.46 10.20 935 213526 41505 42365369
Drug abuse 346.14 10.20 56 214405 104715 42302159
Foetal exposure during pregnancy 344.75 10.20 746 213715 46565 42360309
Toxicity to various agents 301.07 10.20 429 214032 228707 42178167
Psoriatic arthropathy 270.76 10.20 466 213995 24501 42382373
Arthralgia 261.65 10.20 1848 212613 203390 42203484
Completed suicide 244.09 10.20 90 214371 96375 42310499
Drug interaction 191.39 10.20 695 213766 266304 42140570
Psoriasis 155.43 10.20 568 213893 48036 42358838
Sickle cell anaemia with crisis 154.92 10.20 155 214306 4735 42402139
Joint swelling 150.65 10.20 710 213751 67312 42339562
Dysmorphism 141.43 10.20 124 214337 3192 42403682
Intentional overdose 126.79 10.20 50 214411 51406 42355468
Arthritis 113.58 10.20 466 213995 41599 42365275
Product use in unapproved indication 111.98 10.20 512 213949 183944 42222930
Musculoskeletal stiffness 111.56 10.20 580 213881 57185 42349689
Pain 107.69 10.20 1780 212681 243068 42163806
Synovitis 103.78 10.20 237 214224 15330 42391544
Blood pressure fluctuation 102.17 10.20 333 214128 26575 42380299
Premature baby 98.46 10.20 298 214163 22855 42384019
Enthesopathy 95.99 10.20 120 214341 4708 42402166
Blood pressure systolic increased 92.91 10.20 331 214130 27637 42379237
Small for dates baby 92.40 10.20 123 214338 5140 42401734
Off label use 92.10 10.20 2479 211982 635856 41771018
Arthropathy 86.40 10.20 336 214125 29261 42377613
Exposure during pregnancy 85.47 10.20 154 214307 8394 42398480
Hepatic function abnormal 83.09 10.20 82 214379 51485 42355389
Coma 83.07 10.20 88 214373 53466 42353408
Tenosynovitis 81.31 10.20 109 214352 4586 42402288
C-reactive protein abnormal 79.12 10.20 156 214305 9105 42397769
Acute kidney injury 78.96 10.20 1337 213124 366000 42040874
Death 78.04 10.20 1792 212669 469393 41937481
Blood pressure systolic abnormal 77.48 10.20 116 214345 5412 42401462
Disease progression 76.67 10.20 417 214044 143239 42263635
Serotonin syndrome 74.53 10.20 19 214442 25826 42381048
Rhabdomyolysis 72.32 10.20 180 214281 77839 42329035
Speech disorder developmental 71.59 10.20 72 214389 2213 42404661
Neonatal respiratory distress syndrome 69.49 10.20 99 214362 4414 42402460
Overdose 66.94 10.20 287 214174 104977 42301897
Maternal exposure during pregnancy 66.33 10.20 123 214338 6855 42400019
Blood pressure diastolic abnormal 65.91 10.20 114 214347 6014 42400860
Drug resistance 65.61 10.20 46 214415 34202 42372672
Foetal anticonvulsant syndrome 63.79 10.20 51 214410 1151 42405723
Sedation 63.77 10.20 37 214424 30438 42376436
Low birth weight baby 62.45 10.20 148 214313 9807 42397067
Multiple organ dysfunction syndrome 61.43 10.20 265 214196 96770 42310104
Drug dependence 61.34 10.20 35 214426 29059 42377815
Pancytopenia 61.22 10.20 881 213580 116862 42290012
Intentional product misuse 61.20 10.20 138 214323 61762 42345112
Weight decreased 61.20 10.20 1423 213038 206525 42200349
Osteoarthritis 57.88 10.20 260 214201 24145 42382729
Suicide attempt 57.76 10.20 89 214372 46011 42360863
Heart rate decreased 57.35 10.20 347 214114 36185 42370689
Alanine aminotransferase abnormal 57.18 10.20 95 214366 4849 42402025
Hypoglycaemia neonatal 57.07 10.20 62 214399 2088 42404786
Hypospadias 54.56 10.20 78 214383 3489 42403385
Maternal drugs affecting foetus 54.44 10.20 81 214380 3758 42403116
Atrial septal defect 54.38 10.20 122 214339 7797 42399077
Peripheral swelling 52.85 10.20 690 213771 89580 42317294
Learning disorder 52.30 10.20 44 214417 1069 42405805
Febrile neutropenia 51.28 10.20 643 213818 185060 42221814
Blood pressure diastolic decreased 50.33 10.20 140 214321 10235 42396639
Nasopharyngitis 49.99 10.20 644 213817 83352 42323522
Appendicolith 49.69 10.20 5 214456 13451 42393423
Autism spectrum disorder 49.66 10.20 68 214393 2920 42403954
Cryptorchism 49.57 10.20 56 214405 1971 42404903
Joint effusion 48.77 10.20 98 214363 5799 42401075
Angioedema 48.57 10.20 87 214374 42390 42364484
Pain in extremity 48.48 10.20 1044 213417 149560 42257314
Rheumatoid nodule 48.04 10.20 67 214394 2928 42403946
Palmar-plantar erythrodysaesthesia syndrome 47.50 10.20 22 214439 20560 42386314
Drug ineffective for unapproved indication 47.21 10.20 101 214360 46062 42360812
Jaundice neonatal 44.67 10.20 55 214406 2124 42404750
Sleep disorder due to a general medical condition 44.59 10.20 16 214445 17437 42389437
Altered state of consciousness 44.34 10.20 49 214412 29210 42377664
Poisoning 43.96 10.20 10 214451 14689 42392185
Ventricular septal defect 43.65 10.20 79 214382 4320 42402554
Haemoglobin decreased 43.50 10.20 921 213540 131550 42275324
Colitis ulcerative 43.25 10.20 252 214209 25923 42380951
Blood pressure diastolic increased 43.23 10.20 98 214363 6307 42400567
Inflammation 41.91 10.20 303 214158 33544 42373330
Syndactyly 41.83 10.20 36 214425 903 42405971
Haematochezia 41.77 10.20 464 213997 57972 42348902
Infusion related reaction 41.74 10.20 479 213982 60327 42346547
Tongue disorder 41.61 10.20 87 214374 5296 42401578
Grip strength decreased 41.57 10.20 69 214392 3519 42403355
Maternal exposure during breast feeding 41.55 10.20 45 214416 1510 42405364
Body temperature decreased 41.55 10.20 163 214298 14250 42392624
Bradycardia 41.36 10.20 256 214205 85228 42321646
Drug ineffective 41.06 10.20 2678 211783 627519 41779355
No adverse event 41.05 10.20 84 214377 38937 42367937
Blood pressure increased 41.04 10.20 731 213730 101197 42305677
Suicidal ideation 40.91 10.20 116 214345 48045 42358829
Hand deformity 40.40 10.20 70 214391 3698 42403176
Knee arthroplasty 40.16 10.20 116 214345 8665 42398209
Cytomegalovirus infection 39.86 10.20 63 214398 32243 42374631
Cytokine release syndrome 39.50 10.20 105 214356 44422 42362452
Foot deformity 39.28 10.20 82 214379 4986 42401888
Drug reaction with eosinophilia and systemic symptoms 39.03 10.20 97 214364 41978 42364896
Depressed level of consciousness 38.96 10.20 118 214343 47852 42359022
Myelosuppression 38.54 10.20 92 214369 40369 42366505
Pathogen resistance 38.05 10.20 6 214455 11444 42395430
Exposure via breast milk 37.64 10.20 54 214407 2423 42404451
Neuroleptic malignant syndrome 37.12 10.20 32 214429 21440 42385434
Abdominal discomfort 36.69 10.20 557 213904 74698 42332176
Cardiogenic shock 36.42 10.20 78 214383 35562 42371312
Joint laxity 36.12 10.20 24 214437 402 42406472
Toxic epidermal necrolysis 36.10 10.20 49 214412 26701 42380173
Red blood cell sedimentation rate increased 36.04 10.20 121 214340 9803 42397071
C-reactive protein increased 36.00 10.20 483 213978 63077 42343797
Foetal growth restriction 35.84 10.20 81 214380 5202 42401672
Sopor 35.66 10.20 11 214450 13191 42393683
Cardiac murmur 35.64 10.20 143 214318 12632 42394242
Lower respiratory tract infection 35.54 10.20 340 214121 40866 42366008
Polyarthritis 34.34 10.20 78 214383 5026 42401848
Malignant neoplasm progression 34.30 10.20 364 214097 108036 42298838
Bradycardia neonatal 34.27 10.20 38 214423 1310 42405564
Lactic acidosis 34.20 10.20 115 214346 45146 42361728
Ventricular fibrillation 34.17 10.20 62 214399 30061 42376813
Anal fissure 34.07 10.20 79 214382 5160 42401714
Developmental delay 33.97 10.20 59 214402 3123 42403751
Respiratory arrest 33.60 10.20 57 214404 28367 42378507
Wound 33.11 10.20 172 214289 16945 42389929
Drug use disorder 33.04 10.20 6 214455 10327 42396547
Respiratory disorder neonatal 32.99 10.20 45 214416 1925 42404949
Renal impairment 32.94 10.20 375 214086 109853 42297021
Acute hepatic failure 32.61 10.20 23 214438 17050 42389824
Acute chest syndrome 32.35 10.20 33 214428 1032 42405842
Catarrh 32.28 10.20 84 214377 5902 42400972
Drug withdrawal syndrome neonatal 32.07 10.20 70 214391 4391 42402483
Basal cell carcinoma 31.99 10.20 210 214251 22523 42384351
Tendonitis 31.92 10.20 116 214345 9778 42397096
Anaphylactic shock 30.82 10.20 44 214417 23473 42383401
Plagiocephaly 30.80 10.20 25 214436 577 42406297
Caesarean section 30.67 10.20 45 214416 2061 42404813
Psychotic disorder 30.62 10.20 63 214398 29145 42377729
Cardiac failure 30.59 10.20 367 214094 106489 42300385
Talipes 30.03 10.20 46 214415 2190 42404684
Fatigue 29.92 10.20 2562 211899 433079 41973795
Finger deformity 29.92 10.20 39 214422 1596 42405278
Delirium 29.92 10.20 149 214312 52370 42354504
Dysgraphia 29.81 10.20 49 214412 2479 42404395
Hypermobility syndrome 29.69 10.20 20 214441 343 42406531
Hypoglycaemia 29.60 10.20 178 214283 59676 42347198
Pulmonary alveolar haemorrhage 29.58 10.20 19 214442 14797 42392077
Shock 29.53 10.20 64 214397 29057 42377817
Mucocutaneous ulceration 29.49 10.20 23 214438 500 42406374
Neurotoxicity 29.29 10.20 46 214415 23605 42383269
Musculoskeletal pain 29.20 10.20 276 214185 33064 42373810
Congenital hand malformation 28.99 10.20 25 214436 629 42406245
Substance abuse 28.85 10.20 5 214456 8900 42397974
Large for dates baby 28.58 10.20 29 214432 901 42405973
Agitation 28.38 10.20 198 214263 64116 42342758
Burns second degree 28.33 10.20 81 214380 6015 42400859
Ankylosing spondylitis 28.30 10.20 89 214372 6967 42399907
Immune reconstitution inflammatory syndrome 28.22 10.20 8 214453 10135 42396739
Frequent bowel movements 27.88 10.20 194 214267 21213 42385661
Cardiac arrest 27.77 10.20 385 214076 108935 42297939
Forced expiratory volume decreased 27.75 10.20 3 214458 7627 42399247
Joint range of motion decreased 27.69 10.20 94 214367 7659 42399215
Haematocrit decreased 27.66 10.20 283 214178 34625 42372249
Agitation neonatal 27.60 10.20 35 214426 1393 42405481
Electrocardiogram QT prolonged 27.32 10.20 136 214325 47809 42359065
Systemic lupus erythematosus 27.32 10.20 106 214355 9218 42397656
Intentional self-injury 27.09 10.20 22 214439 15180 42391694
Venoocclusive liver disease 27.08 10.20 9 214452 10293 42396581
Aspergillus infection 26.89 10.20 24 214437 15813 42391061
Therapy partial responder 26.69 10.20 37 214424 19984 42386890
Therapeutic product effect decreased 26.68 10.20 308 214153 38842 42368032
Diaphragmatic disorder 26.58 10.20 32 214429 1207 42405667
Language disorder 26.56 10.20 46 214415 2429 42404445
Respiratory failure 26.55 10.20 469 213992 127663 42279211
Tuberculosis 26.55 10.20 111 214350 9988 42396886
BK virus infection 26.22 10.20 6 214455 8778 42398096
Renal failure 26.12 10.20 538 213923 143188 42263686
Respiratory depression 26.03 10.20 34 214427 18834 42388040
Akathisia 25.99 10.20 10 214451 10441 42396433
Hypokalaemia 25.98 10.20 233 214228 71488 42335386
Ultrasound antenatal screen 25.89 10.20 22 214439 542 42406332
Post transplant lymphoproliferative disorder 25.73 10.20 7 214454 9113 42397761
Cytomegalovirus infection reactivation 25.71 10.20 12 214449 11166 42395708
Appendicitis 25.62 10.20 40 214421 20573 42386301
Hydrops foetalis 25.61 10.20 27 214434 878 42405996
Hyperglycaemia 25.61 10.20 131 214330 45728 42361146
Mucormycosis 25.50 10.20 3 214458 7140 42399734
Wrong technique in product usage process 25.42 10.20 119 214342 42516 42364358
Hepatic failure 25.37 10.20 102 214359 37998 42368876
Foetal disorder 25.02 10.20 29 214432 1050 42405824
Skin cancer 24.88 10.20 119 214342 11343 42395531
Trisomy 18 24.83 10.20 26 214435 839 42406035
Arthritis infective 24.63 10.20 60 214401 4046 42402828
Localised infection 24.43 10.20 181 214280 20192 42386682
Drug intolerance 24.41 10.20 553 213908 79871 42327003
Somnolence 23.95 10.20 534 213927 140571 42266303
Parosmia 23.83 10.20 89 214372 7602 42399272
Nasal disorder 23.77 10.20 39 214422 1970 42404904
Gingival pain 23.63 10.20 95 214366 8399 42398475
Maternal exposure before pregnancy 23.40 10.20 28 214433 1049 42405825
Selective eating disorder 23.28 10.20 36 214425 1728 42405146
Astigmatism 23.20 10.20 31 214430 1300 42405574
Hyperbilirubinaemia neonatal 23.08 10.20 25 214436 839 42406035
Lung neoplasm malignant 22.90 10.20 170 214291 18977 42387897
Dyspraxia 22.85 10.20 19 214442 454 42406420
Anal fistula 22.78 10.20 76 214385 6137 42400737
Joint stiffness 22.59 10.20 122 214339 12200 42394674
Blood phosphorus increased 22.47 10.20 18 214443 12507 42394367
Radiation inflammation 22.37 10.20 27 214434 1021 42405853
Tachycardia 22.24 10.20 366 214095 100721 42306153
Vitamin D deficiency 22.22 10.20 90 214371 7983 42398891
Drug withdrawal syndrome 22.15 10.20 47 214414 21502 42385372
Withdrawal syndrome 22.10 10.20 25 214436 14750 42392124
Hypotonia neonatal 22.04 10.20 32 214429 1452 42405422
Temperature regulation disorder 21.76 10.20 28 214433 1131 42405743
Adenovirus infection 21.67 10.20 4 214457 6805 42400069
Crohn's disease 21.65 10.20 47 214414 2937 42403937
Knee deformity 21.62 10.20 23 214438 756 42406118
Oxygen saturation decreased 21.61 10.20 451 214010 64236 42342638
Motor developmental delay 21.54 10.20 22 214439 689 42406185
Cleft lip and palate 21.53 10.20 25 214436 907 42405967
Arthrodesis 21.38 10.20 20 214441 561 42406313
Umbilical hernia 21.20 10.20 68 214393 5379 42401495
Suspected suicide 21.17 10.20 3 214458 6196 42400678
Serum ferritin increased 21.10 10.20 82 214379 7137 42399737
Steroid dependence 21.00 10.20 78 214383 6644 42400230
Post procedural infection 20.53 10.20 70 214391 5715 42401159
Dyslexia 20.36 10.20 16 214445 352 42406522
Thymus disorder 20.35 10.20 14 214447 249 42406625
Hypopnoea 20.23 10.20 86 214375 7796 42399078
Acute graft versus host disease 20.20 10.20 8 214453 8207 42398667
Rebound effect 20.20 10.20 6 214455 7373 42399501
Transient aphasia 20.04 10.20 20 214441 609 42406265
Ankyloglossia congenital 19.98 10.20 16 214445 362 42406512
Central nervous system mass 19.95 10.20 23 214438 828 42406046
Loss of personal independence in daily activities 19.93 10.20 357 214104 49459 42357415
Congenital foot malformation 19.90 10.20 17 214444 422 42406452
Wall motion score index abnormal 19.86 10.20 23 214438 832 42406042
Hypoxia 19.84 10.20 240 214221 69546 42337328
Cellulitis 19.81 10.20 427 214034 61158 42345716
Proteinuria 19.78 10.20 55 214406 22928 42383946
Congenital anomaly 19.71 10.20 31 214430 1510 42405364
Influenza 19.65 10.20 430 214031 61745 42345129
Intellectual disability 19.62 10.20 35 214426 1892 42404982
Ear disorder 19.59 10.20 36 214425 1992 42404882
Metabolic acidosis 19.43 10.20 167 214294 51691 42355183
Spinal disorder 19.43 10.20 59 214402 4532 42402342
Cardiac septal defect 19.31 10.20 24 214437 936 42405938
Aggression 18.97 10.20 137 214324 44026 42362848
Fall 18.93 10.20 1397 213064 233123 42173751
Airway remodelling 18.91 10.20 23 214438 877 42405997
Incorrect route of product administration 18.88 10.20 61 214400 24244 42382630
Pruritus 18.72 10.20 768 213693 188003 42218871
Intervertebral disc degeneration 18.61 10.20 80 214381 7287 42399587
Synovial cyst 18.61 10.20 41 214420 2588 42404286
Red blood cell sedimentation rate 18.59 10.20 25 214436 1055 42405819
Polyomavirus-associated nephropathy 18.53 10.20 3 214458 5612 42401262
Weight increased 18.51 10.20 691 213770 107292 42299582
Cytomegalovirus viraemia 18.51 10.20 15 214446 10362 42396512
Headache 18.51 10.20 1421 213040 237948 42168926
Syringe issue 18.46 10.20 10 214451 8546 42398328
Medical device implantation 18.42 10.20 19 214442 602 42406272
Transfusion-related circulatory overload 18.39 10.20 21 214440 748 42406126
Spina bifida 18.37 10.20 16 214445 408 42406466
Rhinitis 18.31 10.20 113 214348 11864 42395010
Haemolysis 18.30 10.20 96 214365 9493 42397381
Arthritis bacterial 18.26 10.20 68 214393 5800 42401074
Cystitis haemorrhagic 18.25 10.20 7 214454 7322 42399552
Blood parathyroid hormone decreased 18.24 10.20 31 214430 1612 42405262
Multiple congenital abnormalities 18.20 10.20 18 214443 542 42406332
Fistula discharge 18.09 10.20 25 214436 1083 42405791
Renal aplasia 18.08 10.20 21 214440 762 42406112
Squamous cell carcinoma of lung 18.07 10.20 37 214424 2219 42404655
Infection 17.99 10.20 712 213749 111356 42295518
Blood creatine phosphokinase increased 17.96 10.20 156 214305 48182 42358692
Malignant melanoma 17.86 10.20 94 214367 9306 42397568
Oropharyngeal pain 17.85 10.20 307 214154 42203 42364671
Ear infection 17.84 10.20 118 214343 12686 42394188
Joint ankylosis 17.78 10.20 31 214430 1646 42405228
Pulmonary fibrosis 17.77 10.20 209 214252 26472 42380402
Drug dose omission by device 17.61 10.20 4 214457 5882 42400992
Cleft lip 17.58 10.20 14 214447 314 42406560
Sinusitis 17.56 10.20 335 214126 46957 42359917
Atopy 17.44 10.20 23 214438 952 42405922
Alcohol poisoning 17.44 10.20 80 214381 7494 42399380
Limb reduction defect 17.43 10.20 14 214447 318 42406556
Accidental exposure to product 17.40 10.20 49 214412 20344 42386530
Lacrimal disorder 17.36 10.20 14 214447 320 42406554
Pulmonary vasculitis 17.32 10.20 5 214456 6261 42400613
Anti-cyclic citrullinated peptide antibody positive 17.30 10.20 33 214428 1879 42404995
Pneumonia 17.24 10.20 2399 212062 419750 41987124
Congenital bladder anomaly 17.22 10.20 13 214448 269 42406605
Otitis media 17.18 10.20 49 214412 3634 42403240
Cardiotoxicity 17.11 10.20 8 214453 7437 42399437
Weight decrease neonatal 17.10 10.20 14 214447 327 42406547
Hepatic steatosis 17.04 10.20 174 214287 21274 42385600
Acute graft versus host disease in skin 17.03 10.20 8 214453 7416 42399458
Back disorder 17.03 10.20 79 214382 7435 42399439
Constipation 17.01 10.20 656 213805 161635 42245239
Vitamin B12 deficiency 16.98 10.20 59 214402 4863 42402011
Granuloma skin 16.96 10.20 25 214436 1150 42405724
Patent ductus arteriosus 16.95 10.20 47 214414 3429 42403445
Ventricular tachycardia 16.93 10.20 86 214375 30074 42376800
Haemangioma congenital 16.92 10.20 17 214444 522 42406352
Hydrocele 16.85 10.20 39 214422 2544 42404330
Osteonecrosis of jaw 16.83 10.20 45 214416 19004 42387870
Upper respiratory tract infection 16.79 10.20 302 214159 41871 42365003
Posterior reversible encephalopathy syndrome 16.79 10.20 24 214437 12797 42394077
Pneumonia aspiration 16.72 10.20 166 214295 49912 42356962
Hypertelorism 16.69 10.20 18 214443 601 42406273
Pectus excavatum 16.67 10.20 12 214449 230 42406644
Ascites 16.46 10.20 194 214267 56484 42350390
Dermatitis atopic 16.46 10.20 23 214438 12381 42394493
Cerebral haemorrhage 16.20 10.20 122 214339 38844 42368030
Heart rate irregular 16.17 10.20 137 214324 15913 42390961
Vomiting 16.14 10.20 1247 213214 288476 42118398
Disseminated intravascular coagulation 16.11 10.20 67 214394 24727 42382147
Sexual dysfunction 16.01 10.20 7 214454 6768 42400106
Mite allergy 15.98 10.20 3 214458 5043 42401831
Neurological symptom 15.96 10.20 16 214445 9975 42396899
Red blood cell sedimentation rate abnormal 15.95 10.20 49 214412 3787 42403087
Colorectal cancer 15.95 10.20 3 214458 5035 42401839
Device leakage 15.83 10.20 17 214444 10268 42396606
Exposure to toxic agent 15.80 10.20 3 214458 5001 42401873
Immunosuppression 15.70 10.20 84 214377 8369 42398505
Injection site haemorrhage 15.66 10.20 107 214354 11629 42395245
Neck mass 15.60 10.20 31 214430 1819 42405055
Bone cyst 15.56 10.20 29 214432 1622 42405252
Red blood cell count decreased 15.50 10.20 241 214220 32474 42374400
Spondyloarthropathy 15.49 10.20 21 214440 893 42405981
Electrocardiogram QRS complex prolonged 15.46 10.20 5 214456 5818 42401056
Neutropenia neonatal 15.39 10.20 21 214440 899 42405975
Septic arthritis staphylococcal 15.36 10.20 16 214445 513 42406361
Juvenile idiopathic arthritis 15.23 10.20 38 214423 2601 42404273
Pulmonary pain 15.23 10.20 28 214433 1550 42405324
Skin injury 15.22 10.20 38 214423 2603 42404271
Microangiopathy 15.18 10.20 29 214432 1653 42405221
Bursitis 15.16 10.20 67 214394 6177 42400697
Abortion spontaneous 15.05 10.20 14 214447 390 42406484
Carcinoid tumour of the small bowel 14.90 10.20 14 214447 395 42406479
Asphyxia 14.89 10.20 12 214449 8314 42398560
C-reactive protein decreased 14.85 10.20 34 214427 2202 42404672
Mobility decreased 14.83 10.20 255 214206 35051 42371823
Contusion 14.77 10.20 295 214166 41690 42365184
Cholelithiasis 14.73 10.20 181 214280 23165 42383709
Loss of consciousness 14.68 10.20 353 214108 92001 42314873
Polydactyly 14.66 10.20 24 214437 1210 42405664
Disability assessment scale score increased 14.64 10.20 14 214447 404 42406470
Acute respiratory distress syndrome 14.64 10.20 90 214371 30018 42376856
Gastrointestinal infection 14.63 10.20 70 214391 6673 42400201
Agranulocytosis 14.63 10.20 92 214369 30520 42376354
Oesophageal fibrosis 14.62 10.20 10 214451 176 42406698
Dysstasia 14.60 10.20 121 214340 13965 42392909
Chronic graft versus host disease 14.60 10.20 6 214455 6019 42400855
Myoclonus 14.56 10.20 41 214420 17024 42389850
Bronchiolitis 14.52 10.20 48 214413 3858 42403016
Hernia pain 14.49 10.20 12 214449 285 42406589
Neoplasm progression 14.46 10.20 86 214375 28914 42377960
Tooth malformation 14.38 10.20 10 214451 181 42406693
Obsessive-compulsive disorder 14.37 10.20 8 214453 6735 42400139
Glycosylated haemoglobin increased 14.30 10.20 27 214434 12897 42393977
Respiratory rate increased 14.25 10.20 100 214361 10962 42395912
Hypocalcaemia 14.25 10.20 91 214370 30082 42376792
Hypertriglyceridaemia 14.23 10.20 18 214443 10108 42396766
Neck pain 14.18 10.20 221 214240 29793 42377081
Attention deficit hyperactivity disorder 14.16 10.20 41 214420 3067 42403807
Urticaria 14.08 10.20 275 214186 73761 42333113
Low set ears 14.08 10.20 15 214446 494 42406380
Cytomegalovirus chorioretinitis 14.07 10.20 3 214458 4608 42402266
Diverticulum 14.05 10.20 75 214386 7466 42399408
Foetal distress syndrome 14.00 10.20 23 214438 1163 42405711
Drug level increased 13.98 10.20 76 214385 26124 42380750
Nephropathy toxic 13.97 10.20 41 214420 16797 42390077
Exposure via skin contact 13.97 10.20 4 214457 5034 42401840
Hepatic enzyme increased 13.94 10.20 315 214146 45469 42361405
Lung opacity 13.84 10.20 6 214455 5831 42401043
Blister infected 13.72 10.20 15 214446 509 42406365
Impaired work ability 13.70 10.20 106 214355 11985 42394889
Respiratory tract infection viral 13.70 10.20 43 214418 3363 42403511
Microcephaly 13.67 10.20 20 214441 914 42405960
Myasthenia gravis 13.60 10.20 39 214422 16098 42390776
Arnold-Chiari malformation 13.60 10.20 13 214448 375 42406499
Autoscopy 13.58 10.20 11 214450 253 42406621
Maternal exposure timing unspecified 13.54 10.20 13 214448 377 42406497
Hepatitis E antibody positive 13.47 10.20 11 214450 256 42406618
Hyponatraemia 13.46 10.20 398 214063 101064 42305810
Back pain 13.44 10.20 856 213605 140920 42265954
Hypertransaminasaemia 13.39 10.20 16 214445 9211 42397663
Potentiating drug interaction 13.32 10.20 8 214453 6460 42400414
Gangrene neonatal 13.32 10.20 10 214451 205 42406669
Endophthalmitis 13.29 10.20 3 214458 4430 42402444
Cystitis bacterial 13.28 10.20 10 214451 206 42406668
Lung cancer metastatic 13.23 10.20 39 214422 2947 42403927
Diverticular perforation 13.22 10.20 45 214416 3671 42403203
Euglycaemic diabetic ketoacidosis 13.14 10.20 6 214455 5654 42401220
Scoliosis 13.07 10.20 40 214421 3086 42403788
Haemoptysis 13.03 10.20 159 214302 46008 42360866
Haematotoxicity 13.01 10.20 22 214439 10963 42395911
Haemangioma 12.98 10.20 30 214431 1955 42404919
Fistula 12.96 10.20 76 214385 7836 42399038
Hepatic encephalopathy 12.95 10.20 41 214420 16401 42390473
Dry throat 12.95 10.20 38 214423 2864 42404010
Mydriasis 12.95 10.20 15 214446 8755 42398119
Asthma 12.92 10.20 228 214233 62086 42344788
Bone erosion 12.86 10.20 50 214411 4353 42402521
Anaemia vitamin B12 deficiency 12.84 10.20 15 214446 548 42406326
Eosinophilic myocarditis 12.80 10.20 24 214437 1349 42405525
Pleural fibrosis 12.78 10.20 24 214437 1350 42405524
Strabismus 12.71 10.20 33 214428 2315 42404559
Ligament rupture 12.71 10.20 24 214437 1356 42405518
Melaena 12.70 10.20 129 214332 38617 42368257
Rash maculo-papular 12.65 10.20 124 214337 37379 42369495
Anal atresia 12.61 10.20 11 214450 281 42406593
Developmental coordination disorder 12.57 10.20 10 214451 224 42406650
Multiple-drug resistance 12.55 10.20 11 214450 7311 42399563
Lower respiratory tract congestion 12.53 10.20 26 214435 1574 42405300
Educational problem 12.52 10.20 15 214446 563 42406311
Foetal heart rate deceleration abnormality 12.50 10.20 15 214446 564 42406310
Pharyngitis 12.43 10.20 82 214379 8808 42398066
Asymptomatic bacteriuria 12.42 10.20 10 214451 228 42406646
Psychiatric decompensation 12.37 10.20 3 214458 4219 42402655
Vascular insufficiency 12.36 10.20 12 214449 353 42406521
Inguinal hernia 12.34 10.20 82 214379 8830 42398044
Blood albumin decreased 12.26 10.20 125 214336 15277 42391597
Thrombotic microangiopathy 12.26 10.20 36 214425 14746 42392128
Pleuritic pain 12.26 10.20 69 214392 7008 42399866
Blood insulin increased 12.25 10.20 12 214449 357 42406517
Dystonia 12.24 10.20 29 214432 12761 42394113
Gross motor delay 12.20 10.20 12 214449 359 42406515
Abdominal adhesions 12.14 10.20 27 214434 1715 42405159
Hyperammonaemia 12.11 10.20 13 214448 7853 42399021
Hepatitis E virus test positive 12.11 10.20 11 214450 297 42406577
Hypermetropia 12.10 10.20 14 214447 506 42406368
Poor venous access 12.09 10.20 70 214391 7182 42399692
Psychomotor retardation 12.08 10.20 49 214412 4350 42402524
Hallucination 12.06 10.20 210 214251 57297 42349577
Nephrolithiasis 12.04 10.20 256 214205 36574 42370300
Nerve compression 11.97 10.20 46 214415 3982 42402892
Infective pulmonary exacerbation of cystic fibrosis 11.95 10.20 13 214448 7805 42399069
Rotator cuff syndrome 11.93 10.20 65 214396 6521 42400353
Immunodeficiency 11.92 10.20 70 214391 7220 42399654
Hepatitis fulminant 11.92 10.20 5 214456 4954 42401920
Blood test abnormal 11.88 10.20 108 214353 12798 42394076
Vein disorder 11.85 10.20 30 214431 2072 42404802
Muscle twitching 11.85 10.20 26 214435 11754 42395120
Pyrexia 11.84 10.20 1771 212690 392271 42014603
Latent tuberculosis 11.82 10.20 26 214435 1639 42405235
Unresponsive to stimuli 11.82 10.20 101 214360 31302 42375572
Mucosal ulceration 11.80 10.20 23 214438 1331 42405543
Nail bed bleeding 11.80 10.20 13 214448 445 42406429
Skin abrasion 11.79 10.20 76 214385 8099 42398775
Blood folate increased 11.75 10.20 11 214450 309 42406565
Nephrotic syndrome 11.73 10.20 16 214445 8702 42398172
Peripheral artery thrombosis 11.73 10.20 35 214426 2662 42404212
Palindromic rheumatism 11.73 10.20 9 214452 191 42406683
Mania 11.70 10.20 22 214439 10525 42396349
Haemodynamic instability 11.60 10.20 29 214432 12528 42394346
Congenital hydronephrosis 11.57 10.20 17 214444 780 42406094
Tinnitus 11.44 10.20 207 214254 28731 42378143
Disease recurrence 11.37 10.20 95 214366 29583 42377291
Myopia 11.33 10.20 22 214439 1269 42405605
Tender joint count decreased 11.32 10.20 10 214451 260 42406614
Swollen joint count decreased 11.32 10.20 10 214451 260 42406614
Tinea pedis 11.31 10.20 29 214432 2019 42404855
Hypothyroidism 11.28 10.20 105 214356 31979 42374895
Psychomotor skills impaired 11.27 10.20 54 214407 5150 42401724
Fever neonatal 11.27 10.20 8 214453 150 42406724
Protein deficiency 11.26 10.20 10 214451 262 42406612
Stress ulcer 11.19 10.20 10 214451 264 42406610
Dehiscence 11.19 10.20 15 214446 631 42406243
Panniculitis 11.14 10.20 30 214431 2151 42404723
Bronchopulmonary aspergillosis 11.13 10.20 55 214406 19374 42387500
Drug-induced liver injury 11.11 10.20 131 214330 38142 42368732
Cardio-respiratory arrest 11.08 10.20 218 214243 58418 42348456
Excessive cerumen production 11.07 10.20 11 214450 333 42406541
Hallucination, auditory 11.07 10.20 38 214423 14826 42392048
Hand fracture 11.06 10.20 36 214425 2870 42404004
Osteochondrosis 11.06 10.20 23 214438 1395 42405479
Skin graft failure 11.04 10.20 8 214453 155 42406719
Anal spasm 11.04 10.20 8 214453 155 42406719
Hypophosphataemia 11.04 10.20 61 214400 20884 42385990
Palmoplantar pustulosis 10.97 10.20 13 214448 482 42406392
Disinhibition 10.97 10.20 3 214458 3892 42402982
Congenital genital malformation 10.95 10.20 8 214453 157 42406717
Rectal haemorrhage 10.94 10.20 327 214134 49279 42357595
Bronchitis 10.91 10.20 313 214148 46888 42359986
Abnormal behaviour 10.91 10.20 83 214378 26368 42380506
Emphysema 10.88 10.20 99 214362 11736 42395138
Ear malformation 10.86 10.20 11 214450 341 42406533
Gait disturbance 10.85 10.20 600 213861 97400 42309474
Vitamin B complex deficiency 10.83 10.20 13 214448 489 42406385
Visuospatial deficit 10.81 10.20 7 214454 112 42406762
Hip arthroplasty 10.74 10.20 54 214407 5251 42401623
Glomerular filtration rate decreased 10.74 10.20 44 214417 16307 42390567
Non-Hodgkin's lymphoma 10.74 10.20 23 214438 1424 42405450
Facial pain 10.72 10.20 4 214457 4256 42402618
Kyphosis 10.72 10.20 22 214439 1322 42405552
Encephalopathy 10.69 10.20 145 214316 41188 42365686
Brain oedema 10.68 10.20 44 214417 16283 42390591
Fine motor skill dysfunction 10.65 10.20 30 214431 2209 42404665
Dry mouth 10.64 10.20 139 214322 39740 42367134
Necrotising fasciitis streptococcal 10.62 10.20 8 214453 165 42406709
Restlessness 10.60 10.20 95 214366 29154 42377720
Mutism 10.58 10.20 23 214438 1439 42405435
Nail pitting 10.54 10.20 12 214449 426 42406448
PCO2 decreased 10.53 10.20 26 214435 1768 42405106
Blood homocysteine increased 10.50 10.20 10 214451 287 42406587
Complications of transplanted kidney 10.49 10.20 7 214454 5343 42401531
Haemoglobinuria 10.49 10.20 15 214446 671 42406203
Kidney infection 10.43 10.20 64 214397 6706 42400168
Stevens-Johnson syndrome 10.42 10.20 67 214394 22111 42384763
Lung neoplasm 10.41 10.20 49 214412 4639 42402235
Meningeal disorder 10.40 10.20 11 214450 359 42406515
Mesothelioma 10.39 10.20 12 214449 433 42406441
Bone hypertrophy 10.36 10.20 10 214451 292 42406582
Hyperkalaemia 10.32 10.20 317 214144 80141 42326733
Gamma-glutamyltransferase increased 10.32 10.20 109 214352 32388 42374486
Anti-erythropoietin antibody positive 10.27 10.20 17 214444 865 42406009
Pulmonary artery stenosis congenital 10.26 10.20 13 214448 517 42406357
Mean cell volume increased 10.22 10.20 43 214418 3880 42402994
Gastroschisis 10.22 10.20 8 214453 175 42406699

FDA Adverse Event Reporting System (Geriatric)

MedDRA adverse event termLikelihood ratioLikelihood ratio thresholdPatients taking drug having adverse eventPatients taking drug not having adverse eventPatients not taking drug having adverse eventPatients not taking drug not having adverse event
Systemic lupus erythematosus 1194.92 10.01 4246 780586 250092 109554375
Completed suicide 1188.85 10.01 157 784675 242224 109562243
Toxicity to various agents 1181.16 10.01 1005 783827 479550 109324917
Arthropathy 1140.11 10.01 4546 780286 282976 109521491
Synovitis 1104.70 10.01 4356 780476 269736 109534731
Pemphigus 1098.23 10.01 3686 781146 210884 109593583
Hand deformity 1078.26 10.01 3708 781124 214798 109589669
Joint swelling 1021.42 10.01 5990 778842 436855 109367612
Glossodynia 993.10 10.01 3648 781184 218356 109586111
Anti-cyclic citrullinated peptide antibody positive 861 10.01 3046 781786 178938 109625529
Wound 854.92 10.01 3613 781219 230824 109573643
Rheumatoid arthritis 838.52 10.01 4273 780559 295340 109509127
Pericarditis 825.63 10.01 3411 781421 215703 109588764
Drug abuse 799.29 10.01 146 784686 177265 109627202
Maternal exposure during pregnancy 761.88 10.01 3704 781128 251179 109553288
Duodenal ulcer perforation 741.32 10.01 2856 781976 174844 109629623
Abdominal discomfort 730.75 10.01 5042 779790 388816 109415651
Drug interaction 730.46 10.01 1535 783297 498648 109305819
Arthralgia 721.33 10.01 8576 776256 771056 109033411
Infusion related reaction 703.86 10.01 4874 779958 376288 109428179
Helicobacter infection 700.57 10.01 2851 781981 179026 109625441
Swelling 686.42 10.01 4553 780279 346488 109457979
Alopecia 649.84 10.01 4624 780208 360129 109444338
Psoriatic arthropathy 623.84 10.01 2909 781923 193852 109610615
Therapeutic product effect decreased 619.88 10.01 3392 781440 240924 109563543
Intentional overdose 571.66 10.01 121 784711 132380 109672087
Discomfort 559.51 10.01 3003 781829 211704 109592763
Rheumatoid factor positive 545.00 10.01 2111 782721 129529 109674938
Death 536.94 10.01 2844 781988 696025 109108442
Contraindicated product administered 531.74 10.01 3296 781536 244971 109559496
Pain 524.71 10.01 9599 775233 945356 108859111
Impaired healing 507.51 10.01 2744 782088 193973 109610494
Musculoskeletal stiffness 504.29 10.01 3558 781274 276264 109528203
Hepatic enzyme increased 485.25 10.01 3915 780917 316977 109487490
Febrile neutropenia 478.25 10.01 953 783879 315814 109488653
Acute kidney injury 465.30 10.01 2627 782205 632803 109171664
Folliculitis 455.25 10.01 2372 782460 165281 109639186
Nasopharyngitis 439.13 10.01 4503 780329 389858 109414609
Blister 411.20 10.01 2894 781938 224482 109579985
Irritable bowel syndrome 410.29 10.01 2271 782561 161944 109642523
Muscle injury 406.60 10.01 2027 782805 138780 109665687
C-reactive protein abnormal 403.21 10.01 1907 782925 127788 109676679
Drug intolerance 386.30 10.01 4498 780334 402014 109402453
Fibromyalgia 375.83 10.01 2285 782547 168624 109635843
Lower respiratory tract infection 373.32 10.01 2977 781855 240129 109564338
Rheumatic fever 371.35 10.01 1789 783043 120790 109683677
Sleep disorder due to general medical condition, insomnia type 362.31 10.01 1599 783233 104044 109700423
Exposure during pregnancy 352.18 10.01 2213 782619 165211 109639256
Depressed level of consciousness 340.45 10.01 186 784646 112092 109692375
Disease progression 336.70 10.01 772 784060 243262 109561205
Suicide attempt 336.44 10.01 156 784676 103238 109701229
Sinusitis 323.97 10.01 3375 781457 293313 109511154
Cardiac arrest 316.06 10.01 570 784262 196183 109608284
Peripheral swelling 314.40 10.01 4308 780524 399726 109404741
Ill-defined disorder 312.48 10.01 2045 782787 154808 109649659
Osteoarthritis 310.23 10.01 2290 782542 180333 109624134
Hypersensitivity 300.36 10.01 4273 780559 399725 109404742
Malignant neoplasm progression 300.34 10.01 484 784348 174083 109630384
Type 2 diabetes mellitus 291.19 10.01 2205 782627 175027 109629440
Swollen joint count increased 285.11 10.01 1264 783568 82397 109722070
Stomatitis 283.21 10.01 3049 781783 267193 109537274
Weight increased 282.43 10.01 4363 780469 415281 109389186
Rhabdomyolysis 266.78 10.01 276 784556 120125 109684342
Constipation 266.42 10.01 1470 783362 356316 109448151
Inflammation 264.36 10.01 2306 782526 190932 109613535
Overdose 263.14 10.01 818 784014 232976 109571491
Sedation 259.95 10.01 85 784747 69598 109734869
Neutropenia 256.11 10.01 1582 783250 373038 109431429
Treatment failure 253.56 10.01 3046 781786 274188 109530279
Lactic acidosis 251.86 10.01 175 784657 92636 109711831
Bradycardia 244.00 10.01 457 784375 155060 109649407
Multiple organ dysfunction syndrome 241.40 10.01 442 784390 151268 109653199
Contusion 239.88 10.01 2623 782209 230738 109573729
Hepatic function abnormal 236.24 10.01 173 784659 89122 109715345
Facet joint syndrome 233.06 10.01 1326 783506 95502 109708965
Cardiac failure 228.14 10.01 633 784199 186993 109617474
Hyponatraemia 228.00 10.01 786 784046 216867 109587600
Joint range of motion decreased 227.93 10.01 1564 783268 120268 109684199
Coma 224.97 10.01 304 784528 117565 109686902
Red blood cell sedimentation rate abnormal 220.21 10.01 517 784315 23992 109780475
Serotonin syndrome 219.18 10.01 73 784759 59080 109745387
Sickle cell anaemia with crisis 218.69 10.01 303 784529 9242 109795225
Respiratory failure 215.96 10.01 792 784040 214540 109589927
Drug reaction with eosinophilia and systemic symptoms 212.10 10.01 163 784669 81932 109722535
Blood cholesterol increased 212.04 10.01 2124 782708 182661 109621806
Hypotension 211.37 10.01 2539 782293 521310 109283157
Knee arthroplasty 210.60 10.01 967 783865 63981 109740486
Drug resistance 209.88 10.01 69 784763 56305 109748162
Renal failure 209.51 10.01 861 783971 225713 109578754
Grip strength decreased 207.68 10.01 1120 783712 79054 109725413
Electrocardiogram QT prolonged 206.96 10.01 282 784550 108678 109695789
Renal impairment 206.64 10.01 667 784165 187778 109616689
Myelosuppression 204.80 10.01 220 784612 94120 109710347
Somnolence 202.77 10.01 1257 783575 296192 109508275
Drug ineffective for unapproved indication 200.58 10.01 261 784571 102577 109701890
Arthritis 199.42 10.01 1941 782891 165645 109638822
Pregnancy 196.00 10.01 800 784032 50267 109754200
Product use issue 191.63 10.01 3193 781639 308502 109495965
Lip dry 190.29 10.01 1290 783542 98793 109705674
Hip arthroplasty 188.44 10.01 841 783991 54972 109749495
Mobility decreased 185.86 10.01 2535 782297 234887 109569580
Infection 184.81 10.01 3603 781229 358597 109445870
Blood pressure systolic abnormal 184.09 10.01 487 784345 24363 109780104
Cytokine release syndrome 183.67 10.01 138 784694 70168 109734299
Intentional product use issue 181.99 10.01 2617 782215 245289 109559178
Blood pressure fluctuation 180.93 10.01 1026 783806 73798 109730669
Respiratory arrest 180.50 10.01 94 784738 58205 109746262
Injury 176.85 10.01 1981 782851 175284 109629183
Angioedema 176.15 10.01 266 784566 98234 109706233
Hypoglycaemia 175.30 10.01 349 784483 115755 109688712
Blood pressure systolic increased 175.05 10.01 1098 783734 81893 109722574
Blood pressure diastolic abnormal 173.36 10.01 488 784344 25327 109779140
Agitation 172.26 10.01 338 784494 112713 109691754
Musculoskeletal pain 172.12 10.01 2022 782810 181001 109623466
Bursitis 169.18 10.01 1534 783298 128384 109676083
Live birth 166.18 10.01 950 783882 68534 109735933
Hyperhidrosis 164.98 10.01 725 784107 186573 109617894
Off label use 162.61 10.01 8852 775980 1491333 108313134
Sopor 162.54 10.01 31 784801 36515 109767952
Altered state of consciousness 161.26 10.01 105 784727 57521 109746946
Neoplasm progression 160.91 10.01 133 784699 64462 109740005
C-reactive protein increased 160.55 10.01 2302 782530 215617 109588850
Intentional product misuse 155.21 10.01 457 784375 132447 109672020
Red blood cell sedimentation rate increased 152.89 10.01 1016 783816 77286 109727181
Hepatic failure 150.65 10.01 159 784673 68580 109735887
Deep vein thrombosis postoperative 147.32 10.01 819 784013 58472 109745995
Sepsis 144.67 10.01 1554 783278 325792 109478675
Cardio-respiratory arrest 144.38 10.01 386 784446 115450 109689017
Abortion spontaneous 143.60 10.01 552 784280 33730 109770737
Obesity 142.32 10.01 1328 783504 112023 109692444
Cytomegalovirus infection 142.04 10.01 107 784725 54337 109750130
Gastrointestinal disorder 141.89 10.01 2460 782372 239492 109564975
Metabolic acidosis 140.36 10.01 312 784520 99432 109705035
Liver injury 140.20 10.01 1659 783173 148754 109655713
Wound infection 139.65 10.01 1166 783666 95299 109709168
Breast cancer stage III 139.36 10.01 1001 783831 78116 109726351
Hyperglycaemia 137.04 10.01 246 784586 84844 109719623
Anaemia 135.55 10.01 2905 781927 544181 109260286
Sciatica 134.90 10.01 1119 783713 91280 109713187
Tachycardia 134.37 10.01 998 783834 225647 109578820
Peripheral venous disease 132.75 10.01 1037 783795 83080 109721387
Thrombocytopenia 132.30 10.01 1713 783119 347172 109457295
Neuropathy peripheral 130.37 10.01 742 784090 178535 109625932
Hypoxia 130.05 10.01 476 784356 129039 109675428
Shock 129.01 10.01 114 784718 53474 109750993
Joint effusion 128.63 10.01 383 784449 20522 109783945
Drug dependence 127.07 10.01 101 784731 49919 109754548
Anaphylactic shock 123.67 10.01 110 784722 51436 109753031
Pain in extremity 123.02 10.01 4417 780415 482701 109321766
Intentional self-injury 122.48 10.01 56 784776 37373 109767094
Ventricular fibrillation 121.53 10.01 71 784761 41242 109763225
Autoimmune disorder 120.29 10.01 837 783995 64646 109739821
Syncope 119.50 10.01 893 783939 201643 109602824
Respiratory depression 119.42 10.01 39 784793 31962 109772505
Cognitive disorder 118.87 10.01 279 784553 87232 109717235
Poisoning 118.69 10.01 30 784802 29075 109775392
Hyperkalaemia 113.38 10.01 536 784296 135260 109669207
Product use in unapproved indication 113.26 10.01 2367 782465 445010 109359457
Seizure 113.24 10.01 1013 783819 220172 109584295
Condition aggravated 111.92 10.01 6328 778504 728508 109075959
Palmar-plantar erythrodysaesthesia syndrome 111.76 10.01 77 784755 40948 109763519
Bone erosion 110.22 10.01 633 784199 45738 109758729
Neurotoxicity 110.04 10.01 83 784749 42124 109762343
Road traffic accident 109.72 10.01 1206 783626 106192 109698275
Fatigue 109.69 10.01 10033 774799 1205925 108598542
Ventricular tachycardia 109.22 10.01 116 784716 49893 109754574
Foot deformity 108.90 10.01 652 784180 47828 109756639
Disability assessment scale score increased 107.64 10.01 142 784690 4128 109800339
Rash 107.50 10.01 6976 777856 813988 108990479
Joint stiffness 107.22 10.01 831 784001 66412 109738055
Drug use disorder 107.05 10.01 5 784827 18069 109786398
Ascites 107.00 10.01 321 784511 92487 109711980
Disseminated intravascular coagulation 106.61 10.01 82 784750 41204 109763263
General physical health deterioration 105.28 10.01 3848 780984 421447 109383020
Gait inability 104.56 10.01 1451 783381 134925 109669542
Encephalopathy 104.13 10.01 266 784566 80789 109723678
Cardiogenic shock 102.35 10.01 155 784677 57183 109747284
Sedation complication 101.87 10.01 11 784821 19844 109784623
Blood pressure diastolic decreased 101.67 10.01 514 784318 35371 109769096
Neutrophil count decreased 100.60 10.01 478 784354 120463 109684004
Nausea 100.25 10.01 7484 777348 1228206 108576261
Tremor 100.13 10.01 934 783898 201298 109603169
No adverse event 99.02 10.01 237 784595 73602 109730865
Hypoaesthesia 98.85 10.01 2925 781907 311298 109493169
Suicidal ideation 96.45 10.01 342 784490 93595 109710872
Psoriasis 96.45 10.01 1462 783370 138531 109665936
Adverse event 94.79 10.01 1185 783647 107624 109696843
Injection site reaction 94.59 10.01 1008 783824 88062 109716405
Suspected suicide 94.13 10.01 3 784829 15196 109789271
Cerebral haemorrhage 94.07 10.01 200 784632 64768 109739699
Pulmonary fibrosis 93.97 10.01 1123 783709 100919 109703548
Heart rate decreased 93.78 10.01 949 783883 81807 109722660
Lower limb fracture 93.69 10.01 881 783951 74467 109730000
Blood creatine phosphokinase increased 92.97 10.01 241 784591 72836 109731631
Hypokalaemia 92.76 10.01 837 783995 181611 109622856
Myalgia 92.53 10.01 1070 783762 221311 109583156
Acute hepatic failure 92.18 10.01 74 784758 36394 109768073
Mydriasis 91.99 10.01 22 784810 22135 109782332
Enthesopathy 91.88 10.01 244 784588 12234 109792233
Hepatocellular injury 91.27 10.01 136 784696 50506 109753961
Blood creatinine increased 90.40 10.01 845 783987 182044 109622423
Restlessness 90.27 10.01 163 784669 56096 109748371
Neuroleptic malignant syndrome 90.06 10.01 66 784766 33993 109770474
Dehydration 89.84 10.01 1418 783414 278093 109526374
Hypercholesterolaemia 89.12 10.01 1012 783820 89825 109714642
Adjustment disorder with depressed mood 87.84 10.01 573 784259 43310 109761157
Osteoporosis 87.80 10.01 976 783856 86176 109718291
Leukopenia 87.77 10.01 656 784176 148135 109656332
Dry mouth 87.14 10.01 1944 782888 198004 109606463
Polyarthritis 86.64 10.01 314 784518 18649 109785818
Dislocation of vertebra 85.76 10.01 568 784264 43153 109761314
Chest discomfort 85.59 10.01 804 784028 173044 109631423
Orthostatic hypotension 85.42 10.01 217 784615 66032 109738435
Disturbance in attention 84.72 10.01 197 784635 61798 109742669
Dry skin 84.63 10.01 434 784398 107219 109697248
Aspergillus infection 82.77 10.01 39 784793 25577 109778890
Cardiac failure congestive 82.43 10.01 680 784152 150320 109654147
Rheumatoid nodule 81.91 10.01 323 784509 19973 109784494
Joint destruction 81.61 10.01 215 784617 10728 109793739
Vision blurred 81.37 10.01 558 784274 128464 109676003
Drug withdrawal syndrome 81.19 10.01 90 784742 37964 109766503
Appendicolith 81.13 10.01 5 784827 14250 109790217
Hallucination 80.83 10.01 407 784425 101025 109703442
Wrong technique in product usage process 80.64 10.01 332 784500 87016 109717451
Atrial fibrillation 80.33 10.01 1146 783686 228496 109575971
Juvenile idiopathic arthritis 80.09 10.01 149 784683 5858 109798609
Myoclonus 79.67 10.01 70 784762 32928 109771539
Post transplant lymphoproliferative disorder 79.21 10.01 9 784823 15604 109788863
Platelet count decreased 78.86 10.01 1155 783677 229288 109575179
C-reactive protein 78.04 10.01 423 784409 29908 109774559
Night sweats 77.32 10.01 1359 783473 132624 109671843
Myocardial infarction 76.91 10.01 932 783900 191151 109613316
Cholestasis 76.66 10.01 220 784612 64298 109740169
Venoocclusive liver disease 76.57 10.01 9 784823 15198 109789269
Cerebral infarction 76.38 10.01 158 784674 51680 109752787
Blood glucose increased 75.39 10.01 590 784242 131906 109672561
Skin exfoliation 74.91 10.01 343 784489 87308 109717159
Aggression 74.76 10.01 196 784636 59014 109745453
Proteinuria 74.54 10.01 105 784727 39913 109764554
Therapy partial responder 74.40 10.01 92 784740 36969 109767498
Withdrawal syndrome 74.04 10.01 68 784764 31312 109773155
Accidental exposure to product 74.04 10.01 152 784680 49856 109754611
Thrombotic microangiopathy 73.86 10.01 59 784773 29090 109775377
Sleep disorder 73.40 10.01 1888 782944 196756 109607711
Psychotic disorder 72.75 10.01 158 784674 50779 109753688
Dysphagia 72.37 10.01 718 784114 152882 109651585
Disorientation 72.08 10.01 258 784574 70413 109734054
Ejection fraction decreased 71.54 10.01 112 784720 40768 109763699
Temperature regulation disorder 71.52 10.01 5 784827 12821 109791646
Forced expiratory volume decreased 71.04 10.01 6 784826 13170 109791297
Akathisia 71.03 10.01 17 784815 17096 109787371
Pulmonary alveolar haemorrhage 71 10.01 27 784805 20123 109784344
Hypothermia 70.81 10.01 50 784782 26252 109778215
Torsade de pointes 70.61 10.01 36 784796 22564 109781903
BK virus infection 70.57 10.01 6 784826 13100 109791367
Pathogen resistance 70.57 10.01 19 784813 17653 109786814
Posterior reversible encephalopathy syndrome 70.16 10.01 82 784750 33779 109770688
Gamma-glutamyltransferase increased 69.99 10.01 213 784619 61096 109743371
Respiratory distress 69.87 10.01 252 784580 68622 109735845
Onychomadesis 69.33 10.01 558 784274 45105 109759362
Anaphylactic reaction 69.30 10.01 500 784332 113800 109690667
Onychomycosis 69.29 10.01 490 784342 38041 109766426
Dysarthria 69.06 10.01 334 784498 83787 109720680
Cytomegalovirus infection reactivation 69.01 10.01 22 784810 18311 109786156
Drug level increased 69.00 10.01 147 784685 47572 109756895
Bronchopulmonary aspergillosis 68.95 10.01 66 784766 29797 109774670
Exposure to toxic agent 68.92 10.01 6 784826 12852 109791615
Tenosynovitis 68.86 10.01 263 784569 16020 109788447
Miosis 68.71 10.01 35 784797 21948 109782519
Blood pressure diastolic increased 68.53 10.01 290 784542 18517 109785950
Diabetic ketoacidosis 68.25 10.01 121 784711 41937 109762530
Extrapyramidal disorder 67.59 10.01 63 784769 28804 109775663
Haemoptysis 67.26 10.01 269 784563 71085 109733382
White blood cell count decreased 67.06 10.01 1184 783648 228206 109576261
Body temperature decreased 66.59 10.01 470 784362 36465 109768002
Disease recurrence 66.00 10.01 216 784616 60568 109743899
Laryngitis 65.89 10.01 521 784311 41890 109762577
Caesarean section 65.87 10.01 232 784600 13585 109790882
Immune reconstitution inflammatory syndrome 65.64 10.01 17 784815 16209 109788258
Loss of consciousness 65.39 10.01 989 783843 195317 109609150
Blepharospasm 65.05 10.01 635 784197 54216 109750251
Unresponsive to stimuli 64.32 10.01 234 784598 63556 109740911
Substance abuse 63.70 10.01 7 784825 12456 109792011
Creatinine renal clearance decreased 63.45 10.01 38 784794 21777 109782690
Asphyxia 63.34 10.01 12 784820 14203 109790264
Loss of personal independence in daily activities 62.98 10.01 1451 783381 148569 109655898
Lung disorder 62.97 10.01 1699 783133 178348 109626119
Acute respiratory distress syndrome 62.76 10.01 182 784650 53016 109751451
Brain oedema 62.63 10.01 77 784755 31021 109773446
Joint laxity 62.62 10.01 83 784749 2424 109802043
Haematotoxicity 62.34 10.01 36 784796 21046 109783421
Balance disorder 62.21 10.01 528 784304 116032 109688435
X-ray abnormal 61.84 10.01 473 784359 37644 109766823
Abnormal behaviour 61.84 10.01 114 784718 38925 109765542
Acute graft versus host disease 61.56 10.01 9 784823 12872 109791595
Oedema 60.75 10.01 1935 782897 208041 109596426
Dyspnoea 60.53 10.01 6905 777927 1099967 108704500
Wheezing 60.12 10.01 2297 782535 252933 109551534
Status epilepticus 59.64 10.01 82 784750 31489 109772978
Lupus-like syndrome 59.52 10.01 494 784338 40298 109764169
Exostosis 59.47 10.01 542 784290 45414 109759053
Hemiplegia 59.14 10.01 45 784787 22737 109781730
Localised infection 58.95 10.01 514 784318 42534 109761933
Ear infection 58.90 10.01 693 784139 62039 109742428
Melaena 58.79 10.01 269 784563 68488 109735979
Irritability 58.29 10.01 161 784671 47648 109756819
Finger deformity 57.86 10.01 418 784414 32674 109771793
Arrhythmia 57.84 10.01 275 784557 69300 109735167
Dystonia 57.32 10.01 59 784773 25746 109778721
Anti-cyclic citrullinated peptide antibody 57.29 10.01 287 784545 19677 109784790
Gestational diabetes 56.97 10.01 147 784685 7242 109797225
Interstitial lung disease 56.94 10.01 673 784159 138661 109665806
Retinitis 56.91 10.01 409 784423 31918 109772549
Mucormycosis 56.86 10.01 5 784827 10623 109793844
Clostridium difficile colitis 56.74 10.01 143 784689 43635 109760832
Pulmonary oedema 55.98 10.01 451 784381 100208 109704259
Coagulopathy 55.90 10.01 130 784702 40781 109763686
Aphasia 55.87 10.01 222 784610 58775 109745692
Rebound effect 55.32 10.01 18 784814 14788 109789679
Toxic epidermal necrolysis 55.29 10.01 211 784621 56516 109747951
Personality disorder 54.78 10.01 12 784820 12825 109791642
Exposure via skin contact 54.68 10.01 13 784819 13134 109791333
Second primary malignancy 54.65 10.01 30 784802 18038 109786429
Basal cell carcinoma 54.62 10.01 526 784306 44744 109759723
Tumour lysis syndrome 54.27 10.01 84 784748 30717 109773750
Tachypnoea 53.97 10.01 125 784707 39270 109765197
Blood bilirubin increased 53.83 10.01 317 784515 75655 109728812
Speech disorder 53.77 10.01 239 784593 61330 109743137
Neurologic neglect syndrome 53.72 10.01 3 784829 9295 109795172
Lupus vulgaris 53.60 10.01 418 784414 33465 109771002
Inappropriate antidiuretic hormone secretion 53.48 10.01 99 784733 33752 109770715
Pancreatitis acute 53.23 10.01 233 784599 60041 109744426
Eosinophilia 52.98 10.01 221 784611 57715 109746752
Graft versus host disease 52.98 10.01 34 784798 18772 109785695
Hepatic cirrhosis 52.82 10.01 722 784110 66904 109737563
Bronchospasm 52.77 10.01 83 784749 30156 109774311
Psychomotor hyperactivity 52.70 10.01 40 784792 20237 109784230
Transplant rejection 52.52 10.01 58 784774 24509 109779958
Graft versus host disease in gastrointestinal tract 51.48 10.01 3 784829 8965 109795502
Nail disorder 51.33 10.01 633 784199 57302 109747165
Unintentional medical device removal 51.18 10.01 3 784829 8920 109795547
Dyskinesia 51.02 10.01 190 784642 51256 109753211
Haemophagocytic lymphohistiocytosis 51.02 10.01 91 784741 31468 109772999
Dermatitis atopic 50.64 10.01 64 784768 25477 109778990
Diarrhoea 50.55 10.01 7204 777628 1132301 108672166
Osteonecrosis of jaw 50.51 10.01 173 784659 47844 109756623
Device difficult to use 50.29 10.01 36 784796 18769 109785698
Drug dose omission by device 50.24 10.01 20 784812 14496 109789971
COVID-19 50.14 10.01 1339 783493 243721 109560746
Septic shock 49.97 10.01 801 784031 156727 109647740
Joint dislocation 49.85 10.01 414 784418 33776 109770691
Prescribed overdose 49.68 10.01 886 783946 86695 109717772
Adenovirus infection 49.59 10.01 9 784823 10985 109793482
Stevens-Johnson syndrome 49.32 10.01 169 784663 46732 109757735
Chronic kidney disease 49.06 10.01 328 784504 75963 109728504
Cytomegalovirus viraemia 48.84 10.01 33 784799 17731 109786736
Maternal exposure timing unspecified 48.73 10.01 285 784547 20728 109783739
Cytopenia 48.54 10.01 87 784745 30029 109774438
Hypomagnesaemia 48.23 10.01 242 784590 60128 109744339
Hypophosphataemia 48.16 10.01 102 784730 33080 109771387
Pulmonary embolism 47.59 10.01 1158 783674 213316 109591151
Blood calcium decreased 47.31 10.01 116 784716 35729 109768738
Acute respiratory failure 47.19 10.01 326 784506 74934 109729533
Mental status changes 47.11 10.01 331 784501 75791 109728676
Acute chest syndrome 47.05 10.01 66 784766 2037 109802430
Red blood cell sedimentation rate 46.85 10.01 110 784722 5104 109799363
Face oedema 46.82 10.01 105 784727 33364 109771103
Mania 46.81 10.01 47 784785 20749 109783718
Angina pectoris 46.80 10.01 255 784577 62040 109742427
Rash erythematous 46.73 10.01 364 784468 81468 109722999
Lymphocyte count decreased 46.57 10.01 228 784604 57015 109747452
Polyomavirus-associated nephropathy 46.31 10.01 3 784829 8198 109796269
Palpitations 46.13 10.01 823 784009 158389 109646078
Blood alkaline phosphatase increased 46.11 10.01 304 784528 70631 109733836
Hypothyroidism 46.09 10.01 315 784517 72584 109731883
Acute graft versus host disease in skin 45.91 10.01 10 784822 10730 109793737
Muscle rigidity 45.82 10.01 62 784770 23969 109780498
Hallucination, visual 45.63 10.01 137 784695 39468 109764999
Haemorrhage intracranial 45.52 10.01 85 784747 28884 109775583
Carotid artery thrombosis 45.45 10.01 7 784825 9631 109794836
Tendonitis 44.76 10.01 328 784504 25755 109778712
Pleural effusion 44.66 10.01 941 783891 176768 109627699
Drug tolerance decreased 44.26 10.01 341 784491 27199 109777268
Wheelchair user 43.89 10.01 139 784693 7703 109796764
Back injury 43.78 10.01 522 784310 46877 109757590
Maternal exposure before pregnancy 43.65 10.01 132 784700 7133 109797334
Gastrointestinal haemorrhage 43.51 10.01 870 783962 164648 109639819
Muscle twitching 43.46 10.01 92 784740 29843 109774624
Metastases to bone 43.42 10.01 99 784733 31273 109773194
Metastases to central nervous system 43.37 10.01 59 784773 22758 109781709
Acute generalised exanthematous pustulosis 43.25 10.01 54 784778 21610 109782857
Hyperbilirubinaemia 43.09 10.01 96 784736 30575 109773892
Injection site erythema 43.03 10.01 922 783910 93254 109711213
Hemiparesis 42.98 10.01 163 784669 43740 109760727
Rash maculo-papular 42.92 10.01 329 784503 73893 109730574
Pneumonia aspiration 42.89 10.01 369 784463 80864 109723603
Obstructive airways disorder 42.85 10.01 175 784657 45974 109758493
Prescribed underdose 42.71 10.01 675 784157 64499 109739968
Bradyphrenia 42.53 10.01 15 784817 11713 109792754
Metastases to liver 42.52 10.01 120 784712 35266 109769201
Coordination abnormal 42.38 10.01 71 784761 25157 109779310
Paradoxical drug reaction 42.25 10.01 9 784823 9808 109794659
Tongue disorder 42.06 10.01 207 784625 14091 109790376
Agranulocytosis 42.02 10.01 261 784571 61499 109742968
Cerebrovascular accident 41.82 10.01 973 783859 180311 109624156
Erythema multiforme 41.69 10.01 53 784779 21044 109783423
Emotional distress 41.68 10.01 170 784662 44677 109759790
Urinary retention 41.67 10.01 306 784526 69377 109735090
Blood pressure decreased 41.41 10.01 571 784261 114520 109689947
Alanine aminotransferase abnormal 41.33 10.01 153 784679 9181 109795286
Flushing 41.22 10.01 510 784322 104226 109700241
Leukocytosis 41.18 10.01 219 784613 53609 109750858
Procedural pain 40.99 10.01 123 784709 35442 109769025
Parkinsonism 40.55 10.01 59 784773 22128 109782339
Bacteraemia 40.46 10.01 159 784673 42231 109762236
Hyperthermia 40.44 10.01 55 784777 21217 109783250
Blood phosphorus increased 40.25 10.01 34 784798 16306 109788161
Pyrexia 40.22 10.01 5675 779157 892590 108911877
Acidosis 40.12 10.01 61 784771 22470 109781997
Multiple-drug resistance 40.00 10.01 22 784810 13213 109791254
Nodule 39.79 10.01 380 784452 32251 109772216
Toxic skin eruption 39.58 10.01 85 784747 27430 109777037
Cardiotoxicity 39.33 10.01 37 784795 16844 109787623
Cardiomyopathy 39.33 10.01 115 784717 33410 109771057
Ischaemic stroke 39.24 10.01 155 784677 41108 109763359
Injection site pruritus 39.12 10.01 545 784287 50713 109753754
Vomiting 39.08 10.01 5768 779064 904907 108899560
Coronary artery disease 39.04 10.01 323 784509 71367 109733100
Aspartate aminotransferase increased 38.99 10.01 851 783981 159085 109645382
Neck deformity 38.98 10.01 57 784775 1829 109802638
Disability 38.88 10.01 356 784476 29867 109774600
Haemorrhage 38.87 10.01 528 784304 106164 109698303
Fracture 38.77 10.01 305 784527 24483 109779984
Sinus tachycardia 38.68 10.01 173 784659 44320 109760147
Premature labour 38.67 10.01 148 784684 9024 109795443
Femur fracture 38.59 10.01 484 784348 43985 109760482
Appendicitis 38.45 10.01 91 784741 28373 109776094
Generalised tonic-clonic seizure 38.29 10.01 229 784603 54451 109750016
Glycosylated haemoglobin increased 38.28 10.01 68 784764 23551 109780916
Chronic graft versus host disease 38.08 10.01 10 784822 9447 109795020
Colitis 37.77 10.01 505 784327 101818 109702649
Pseudomonas infection 37.66 10.01 89 784743 27764 109776703
Hepatotoxicity 37.62 10.01 279 784553 63121 109741346
Premature rupture of membranes 37.57 10.01 94 784738 4543 109799924
Myocarditis 37.55 10.01 100 784732 29955 109774512
Electrocardiogram QRS complex prolonged 37.42 10.01 23 784809 12998 109791469
Multiple sclerosis relapse 37.00 10.01 207 784625 50033 109754434
Synovial cyst 36.91 10.01 170 784662 11260 109793207
Shock haemorrhagic 36.89 10.01 87 784745 27160 109777307
Depressed mood 36.85 10.01 266 784566 60543 109743924
Tenderness 36.49 10.01 344 784488 29093 109775374
Ankylosing spondylitis 36.37 10.01 212 784620 15400 109789067
Tardive dyskinesia 36.31 10.01 26 784806 13553 109790914
Epstein-Barr virus infection 36.07 10.01 48 784784 18690 109785777
Latent tuberculosis 35.84 10.01 84 784748 3893 109800574
Diabetes mellitus 35.78 10.01 493 784339 98888 109705579
Fear 35.61 10.01 69 784763 23124 109781343
Skin haemorrhage 35.46 10.01 77 784755 24750 109779717
Motor dysfunction 35.44 10.01 75 784757 24331 109780136
Diabetes insipidus 35.40 10.01 3 784829 6567 109797900
Haematoma 35.34 10.01 256 784576 58220 109746247
Schizophrenia 35.23 10.01 63 784769 21763 109782704
Conjunctivitis allergic 35.15 10.01 4 784828 6927 109797540
Migraine 35.14 10.01 1522 783310 170130 109634337
Acute myeloid leukaemia 35.08 10.01 145 784687 37965 109766502
Proctitis 35.06 10.01 41 784791 16886 109787581
Hyperuricaemia 34.87 10.01 31 784801 14500 109789967
Klebsiella infection 34.84 10.01 55 784777 19954 109784513
Blood parathyroid hormone decreased 34.66 10.01 184 784648 12905 109791562
Graft versus host disease in skin 34.65 10.01 8 784824 8246 109796221
Subdural haematoma 34.62 10.01 137 784695 36317 109768150
Smear cervix abnormal 34.58 10.01 66 784766 2646 109801821
Hepatic encephalopathy 34.56 10.01 95 784737 28161 109776306
Haemodynamic instability 34.36 10.01 69 784763 22819 109781648
Tuberculosis 34.31 10.01 230 784602 17544 109786923
Potentiating drug interaction 34.26 10.01 20 784812 11623 109792844
Fluid retention 34.25 10.01 467 784365 93840 109710627
Ileus 34.19 10.01 108 784724 30621 109773846
Device leakage 34.18 10.01 38 784794 16010 109788457
Cardiac failure acute 34.12 10.01 75 784757 24003 109780464
Acute myocardial infarction 34.09 10.01 405 784427 83372 109721095
Spinal stenosis 34.07 10.01 242 784590 18814 109785653
Seronegative arthritis 34.05 10.01 184 784648 12993 109791474
Nocardiosis 34.04 10.01 6 784826 7480 109796987
Eating disorder 33.95 10.01 109 784723 30749 109773718
Infective pulmonary exacerbation of cystic fibrosis 33.69 10.01 33 784799 14738 109789729
Anuria 33.53 10.01 77 784755 24264 109780203
Feeling abnormal 33.49 10.01 1001 783831 179710 109624757
Glomerular filtration rate decreased 33.48 10.01 100 784732 28856 109775611
Cystitis haemorrhagic 33.14 10.01 23 784809 12186 109792281
Scleritis 33.06 10.01 99 784733 5321 109799146
Stress cardiomyopathy 33.04 10.01 38 784794 15768 109788699
Arthritis infective 32.86 10.01 154 784678 10275 109794192
Vaginal flatulence 32.80 10.01 23 784809 12121 109792346
Device expulsion 32.69 10.01 111 784721 30780 109773687
Respiratory acidosis 32.57 10.01 30 784802 13796 109790671
Bone pain 32.57 10.01 300 784532 64833 109739634
Neck mass 32.24 10.01 91 784741 4730 109799737
Granuloma skin 32.23 10.01 162 784670 11121 109793346
Enterocolitis 32.13 10.01 53 784779 18896 109785571
Hyperammonaemia 32.11 10.01 30 784802 13702 109790765
Candida infection 32.09 10.01 204 784628 47805 109756662
Hepatitis B reactivation 31.93 10.01 7 784825 7477 109796990
Product prescribing error 31.86 10.01 223 784609 51108 109753359
Sinus bradycardia 31.85 10.01 105 784727 29378 109775089
Food allergy 31.82 10.01 58 784774 19890 109784577
Oliguria 31.81 10.01 52 784780 18605 109785862
Dissociation 31.78 10.01 15 784817 9827 109794640
Jaundice cholestatic 31.77 10.01 34 784798 14574 109789893
Dust allergy 31.63 10.01 3 784829 5998 109798469
Antinuclear antibody positive 31.58 10.01 139 784693 9029 109795438
Liver disorder 31.56 10.01 1272 783560 140971 109663496
Immune effector cell-associated neurotoxicity syndrome 31.49 10.01 35 784797 14747 109789720
Limb deformity 31.47 10.01 77 784755 3669 109800798
Rhinitis allergic 31.45 10.01 49 784783 17873 109786594
Pneumothorax 31.40 10.01 136 784696 35149 109769318
Jaundice 31.30 10.01 269 784563 58967 109745500
Mental disorder 31.27 10.01 155 784677 38636 109765831
Polyneuropathy 31.24 10.01 119 784713 31893 109772574
End stage renal disease 31.17 10.01 66 784766 21407 109783060
Multiple fractures 31.15 10.01 136 784696 8804 109795663
Adjustment disorder 31.12 10.01 19 784813 10776 109793691
Blood lactic acid increased 31.00 10.01 40 784792 15781 109788686
Nephropathy toxic 30.98 10.01 96 784736 27382 109777085
Mouth ulceration 30.95 10.01 497 784335 47641 109756826
Colorectal cancer 30.82 10.01 13 784819 9101 109795366
Pemphigoid 30.81 10.01 58 784774 19649 109784818
Sexual dysfunction 30.78 10.01 11 784821 8519 109795948
Generalised oedema 30.71 10.01 113 784719 30591 109773876
Labelled drug-drug interaction medication error 30.53 10.01 106 784726 29196 109775271
Pre-eclampsia 30.45 10.01 132 784700 8518 109795949
Paraesthesia oral 30.44 10.01 129 784703 33542 109770925
Pulmonary vasculitis 30.40 10.01 5 784827 6555 109797912
Gastroenteritis viral 30.22 10.01 347 784485 30879 109773588
Cardiac failure chronic 30.20 10.01 32 784800 13779 109790688
Metastases to lung 30.15 10.01 75 784757 22988 109781479
Hypernatraemia 30.13 10.01 50 784782 17783 109786684
Euglycaemic diabetic ketoacidosis 30.11 10.01 23 784809 11600 109792867
Rotator cuff repair 29.95 10.01 56 784776 2210 109802257
Drug tolerance 29.87 10.01 211 784621 16374 109788093
Myasthenia gravis 29.67 10.01 68 784764 21443 109783024
Liver function test increased 29.65 10.01 831 784001 87717 109716750
Acute coronary syndrome 29.56 10.01 76 784756 23036 109781431
Bacterial infection 29.56 10.01 198 784634 45838 109758629
Febrile bone marrow aplasia 29.48 10.01 49 784783 17416 109787051
Neck pain 29.41 10.01 1110 783722 122020 109682447
Cyanosis 29.39 10.01 110 784722 29631 109774836
Skin ulcer 29.36 10.01 624 784208 63021 109741446
Chills 29.33 10.01 1081 783751 189499 109614968
Pulmonary arterial hypertension 29.30 10.01 125 784707 32443 109772024
Hallucination, auditory 29.21 10.01 93 784739 26304 109778163
Device use error 29.12 10.01 14 784818 9075 109795392
Pneumatosis intestinalis 29.11 10.01 12 784820 8517 109795950
Lip swelling 29.10 10.01 225 784607 50442 109754025
Hyperlipidaemia 29.03 10.01 143 784689 35705 109768762
Malignant mediastinal neoplasm 28.99 10.01 42 784790 1336 109803131
Delusion 28.96 10.01 80 784752 23675 109780792
Lethargy 28.94 10.01 478 784354 93098 109711369
Blood urea increased 28.85 10.01 250 784582 54707 109749760
Synovial disorder 28.74 10.01 65 784767 2942 109801525
Hepatitis acute 28.67 10.01 56 784776 18710 109785757
Diplopia 28.52 10.01 177 784655 41717 109762750
Device related infection 28.47 10.01 164 784668 39355 109765112
Radiculopathy 28.43 10.01 59 784773 19277 109785190
Pulseless electrical activity 28.29 10.01 47 784785 16710 109787757
Dermatitis acneiform 28.22 10.01 29 784803 12666 109791801
Atrial tachycardia 28.11 10.01 15 784817 9163 109795304
Hypoalbuminaemia 28.09 10.01 108 784724 28866 109775601
Pruritus genital 28.03 10.01 6 784826 6516 109797951
Hypomania 28.03 10.01 19 784813 10191 109794276
Vasoplegia syndrome 27.94 10.01 3 784829 5436 109799031
Anxiety 27.94 10.01 2089 782743 342989 109461478
Pulmonary haemorrhage 27.93 10.01 46 784786 16410 109788057
Panniculitis 27.92 10.01 198 784634 15384 109789083
Mite allergy 27.86 10.01 4 784828 5799 109798668
Cytomegalovirus chorioretinitis 27.83 10.01 8 784824 7120 109797347
Multiple drug therapy 27.80 10.01 11 784821 8003 109796464
Lung opacity 27.79 10.01 25 784807 11627 109792840
Hyperlactacidaemia 27.73 10.01 12 784820 8274 109796193
Therapy non-responder 27.71 10.01 1374 783458 155933 109648534
Erythema 27.63 10.01 1740 783092 289707 109514760
Rheumatoid lung 27.57 10.01 80 784752 4224 109800243
Transaminases increased 27.53 10.01 302 784530 63088 109741379
Premature delivery 27.27 10.01 335 784497 30297 109774170
Endophthalmitis 27.18 10.01 12 784820 8175 109796292
Troponin increased 26.93 10.01 114 784718 29652 109774815
Bronchitis 26.92 10.01 1368 783464 155664 109648803
Pancytopenia 26.90 10.01 1779 783053 207834 109596633
Myopathy 26.88 10.01 89 784743 24871 109779596
Synovial fluid analysis 26.80 10.01 59 784773 2622 109801845
Paranoia 26.79 10.01 76 784756 22298 109782169
Sleep terror 26.60 10.01 7 784825 6603 109797864
Ankle arthroplasty 26.48 10.01 57 784775 2494 109801973
Female genital tract fistula 26.37 10.01 48 784784 16471 109787996
Sensory loss 26.35 10.01 72 784760 21385 109783082
Hepatitis cholestatic 26.33 10.01 53 784779 17513 109786954
Hepatitis fulminant 26.20 10.01 14 784818 8546 109795921
Subarachnoid haemorrhage 26.11 10.01 115 784717 29587 109774880
Paralysis 26.11 10.01 44 784788 15556 109788911
Skin toxicity 26.10 10.01 27 784805 11756 109792711
Chronic sinusitis 25.96 10.01 91 784741 24993 109779474
Bone disorder 25.94 10.01 247 784585 20945 109783522
Blood pressure increased 25.75 10.01 2149 782683 256224 109548243
Circulatory collapse 25.60 10.01 189 784643 42804 109761663
Toxic encephalopathy 25.39 10.01 43 784789 15171 109789296
Pneumonia bacterial 25.38 10.01 98 784734 26163 109778304
Pulmonary congestion 25.38 10.01 123 784709 30843 109773624
Alanine aminotransferase increased 25.32 10.01 1056 783776 182717 109621750
Peripheral sensory neuropathy 25.29 10.01 50 784782 16630 109787837
Eye pruritus 25.26 10.01 133 784699 32642 109771825
Hypocalcaemia 25.08 10.01 320 784512 65046 109739421
Tenosynovitis stenosans 25.07 10.01 69 784763 3534 109800933
Adverse drug reaction 25.07 10.01 951 783881 104608 109699859
Hyperpyrexia 24.99 10.01 13 784819 8056 109796411
Bladder cancer 24.99 10.01 68 784764 20224 109784243
Myocardial ischaemia 24.89 10.01 101 784731 26583 109777884
Affect lability 24.84 10.01 60 784772 18577 109785890
Product administered to patient of inappropriate age 24.81 10.01 13 784819 8023 109796444
Virologic failure 24.76 10.01 3 784829 4949 109799518
Drug effective for unapproved indication 24.61 10.01 39 784793 14128 109790339
Diabetes mellitus inadequate control 24.56 10.01 118 784714 29657 109774810
Epistaxis 24.44 10.01 721 784111 129651 109674816
Cleft lip and palate 24.36 10.01 28 784804 704 109803763
International normalised ratio increased 24.35 10.01 451 784381 86321 109718146
Normal newborn 24.28 10.01 250 784582 21646 109782821
Progressive multifocal leukoencephalopathy 24.21 10.01 93 784739 24863 109779604
Hypogammaglobulinaemia 24.18 10.01 68 784764 20008 109784459
Cross sensitivity reaction 24.17 10.01 5 784827 5562 109798905
Immune-mediated enterocolitis 24.11 10.01 22 784810 10163 109794304
Immune-mediated myositis 24.05 10.01 7 784825 6179 109798288
Product preparation error 24.02 10.01 25 784807 10854 109793613
Gangrene 23.91 10.01 50 784782 16291 109788176
Joint injury 23.90 10.01 408 784424 39586 109764881
Foot fracture 23.88 10.01 282 784550 25264 109779203
Loose body in joint 23.86 10.01 39 784793 1381 109803086
Lymphopenia 23.73 10.01 177 784655 39993 109764474
Ventricular arrhythmia 23.63 10.01 22 784810 10065 109794402
Blood lactate dehydrogenase increased 23.57 10.01 201 784631 44133 109760334
Walking aid user 23.53 10.01 277 784555 24798 109779669
Affective disorder 23.53 10.01 27 784805 11214 109793253
Atrioventricular block complete 23.47 10.01 69 784763 20013 109784454
Visual acuity reduced 23.46 10.01 133 784699 32040 109772427
Respiration abnormal 23.45 10.01 21 784811 9788 109794679
Skin papilloma 23.34 10.01 104 784728 6792 109797675
Product label confusion 23.31 10.01 255 784577 22422 109782045
Product prescribing issue 23.30 10.01 34 784798 12738 109791729
Thrombosis 23.19 10.01 590 784242 108072 109696395
Hypercapnia 23.14 10.01 27 784805 11132 109793335
Right ventricular failure 23.12 10.01 100 784732 25854 109778613
Palmoplantar keratoderma 23.06 10.01 5 784827 5382 109799085
Nasal oedema 23.04 10.01 103 784729 6736 109797731
Polyuria 22.94 10.01 58 784774 17680 109786787
Hydrops foetalis 22.90 10.01 28 784804 753 109803714
Amyloid arthropathy 22.81 10.01 42 784790 1638 109802829
Accidental death 22.81 10.01 4 784828 5005 109799462
Macular degeneration 22.80 10.01 78 784754 21581 109782886
Kidney transplant rejection 22.78 10.01 31 784801 11956 109792511
Strongyloidiasis 22.67 10.01 4 784828 4982 109799485
Poor venous access 22.62 10.01 270 784562 24252 109780215
Hepatocellular carcinoma 22.62 10.01 22 784810 9858 109794609
Postoperative wound infection 22.57 10.01 190 784642 15563 109788904
Nail operation 22.56 10.01 42 784790 1652 109802815
Bradykinesia 22.48 10.01 26 784806 10762 109793705
Haematemesis 22.44 10.01 290 784542 58818 109745649
Presyncope 22.40 10.01 230 784602 48657 109755810
Nasal polyps 22.31 10.01 37 784795 13163 109791304
Hypoxic-ischaemic encephalopathy 22.30 10.01 18 784814 8829 109795638
Rales 22.23 10.01 95 784737 24644 109779823
Renal tubular necrosis 22.21 10.01 126 784706 30349 109774118
Exposure via ingestion 22.13 10.01 4 784828 4896 109799571
Blindness 22.05 10.01 159 784673 36200 109768267
Spondylitis 22.05 10.01 147 784685 11191 109793276
Pericardial effusion 21.99 10.01 280 784552 56937 109747530
Ultrasound antenatal screen 21.82 10.01 26 784806 680 109803787
COVID-19 pneumonia 21.78 10.01 164 784668 36979 109767488
Human antichimeric antibody positive 21.73 10.01 42 784790 1700 109802767
Dyspnoea exertional 21.68 10.01 567 784265 103493 109700974
Acute pulmonary oedema 21.65 10.01 56 784776 16940 109787527
Venoocclusive disease 21.57 10.01 9 784823 6341 109798126
Sleep disorder due to a general medical condition 21.55 10.01 251 784581 51861 109752606
Acute myeloid leukaemia recurrent 21.54 10.01 5 784827 5134 109799333
Fracture delayed union 21.51 10.01 48 784784 2153 109802314
Product administration error 21.50 10.01 165 784667 37052 109767415
Ulcer haemorrhage 21.48 10.01 250 784582 22321 109782146
Mucocutaneous ulceration 21.46 10.01 27 784805 748 109803719
Gastric haemorrhage 21.40 10.01 51 784781 15864 109788603
Ketoacidosis 21.36 10.01 24 784808 10063 109794404
Pulmonary hypertension 21.31 10.01 270 784562 54950 109749517
Full blood count abnormal 21.28 10.01 275 784557 55777 109748690
Hyperprolactinaemia 21.26 10.01 10 784822 6565 109797902
Sputum discoloured 21.21 10.01 114 784718 27831 109776636
Atrioventricular block 21.20 10.01 56 784776 16821 109787646
Epilepsy 21.05 10.01 891 783941 99318 109705149
Transplant dysfunction 20.92 10.01 17 784815 8311 109796156
Foot operation 20.89 10.01 105 784727 7208 109797259
Dysphonia 20.89 10.01 396 784436 75533 109728934
Type 1 diabetes mellitus 20.88 10.01 20 784812 9027 109795440
Acute graft versus host disease in intestine 20.82 10.01 7 784825 5632 109798835
Bacterial sepsis 20.80 10.01 26 784806 10400 109794067
Product dose omission issue 20.78 10.01 1983 782849 319799 109484668
Intervertebral disc degeneration 20.77 10.01 208 784624 17877 109786590
Fear of injection 20.75 10.01 121 784711 8790 109795677
Immunosuppressant drug level increased 20.63 10.01 32 784800 11692 109792775
Vascular device infection 20.58 10.01 55 784777 16457 109788010
Therapeutic response decreased 20.27 10.01 858 783974 95641 109708826
Capillary leak syndrome 20.13 10.01 5 784827 4903 109799564
Bradypnoea 20.10 10.01 19 784813 8630 109795837
Hypertransaminasaemia 20.08 10.01 96 784736 24159 109780308
Joint noise 20.07 10.01 81 784751 5062 109799405
Acute lymphocytic leukaemia recurrent 19.98 10.01 8 784824 5779 109798688
Renal injury 19.97 10.01 67 784765 18646 109785821
Systemic inflammatory response syndrome 19.86 10.01 39 784793 13004 109791463
Arterial occlusive disease 19.84 10.01 50 784782 15258 109789209
Lymphatic fistula 19.83 10.01 37 784795 1458 109803009
Lipase increased 19.82 10.01 67 784765 18605 109785862
Human herpesvirus 6 infection 19.80 10.01 11 784821 6570 109797897
Ventricular extrasystoles 19.70 10.01 88 784744 22553 109781914
Skin cancer 19.69 10.01 203 784629 17581 109786886
Vascular stent thrombosis 19.67 10.01 3 784829 4158 109800309
Femoral hernia incarcerated 19.58 10.01 37 784795 1472 109802995
Ingrown hair 19.55 10.01 26 784806 762 109803705
Hydrocephalus 19.54 10.01 27 784805 10348 109794119
Salivary hypersecretion 19.54 10.01 61 784771 17360 109787107
Anti-neutrophil cytoplasmic antibody positive vasculitis 19.52 10.01 7 784825 5410 109799057
Abdominal pain upper 19.46 10.01 2794 782038 346317 109458150
Amylase increased 19.44 10.01 37 784795 12482 109791985
Trisomy 18 19.41 10.01 23 784809 598 109803869
Metastasis 19.40 10.01 18 784814 8249 109796218
Hyperphosphataemia 19.35 10.01 56 784776 16325 109788142
Purpura 19.34 10.01 98 784734 24290 109780177
Heparin-induced thrombocytopenia 19.33 10.01 32 784800 11392 109793075
Hypertriglyceridaemia 19.25 10.01 55 784777 16099 109788368
Anosmia 19.24 10.01 37 784795 12435 109792032
Post procedural infection 18.96 10.01 165 784667 13644 109790823
Linear IgA disease 18.94 10.01 4 784828 4385 109800082
Polydipsia 18.93 10.01 16 784816 7672 109796795
Skin burning sensation 18.89 10.01 85 784747 21740 109782727
Foetal exposure during pregnancy 18.86 10.01 104 784728 7401 109797066
Oesophageal carcinoma 18.84 10.01 33 784799 11491 109792976
Ileus paralytic 18.83 10.01 34 784798 11703 109792764
Body height below normal 18.76 10.01 44 784788 2040 109802427
Systemic candida 18.75 10.01 26 784806 9948 109794519
Incoherent 18.69 10.01 19 784813 8339 109796128
Laryngospasm 18.67 10.01 5 784827 4663 109799804
Breast cancer stage I 18.66 10.01 15 784817 7372 109797095
Dysgeusia 18.64 10.01 367 784465 69618 109734849
Wound infection pseudomonas 18.62 10.01 48 784784 2363 109802104
Oropharyngeal pain 18.60 10.01 1155 783677 134121 109670346
Confusional state 18.58 10.01 3683 781149 464997 109339470
Weight decreased 18.54 10.01 3678 781154 464379 109340088
Total lung capacity decreased 18.53 10.01 14 784818 7100 109797367
Temperature intolerance 18.52 10.01 45 784787 13905 109790562
Vaginal discharge 18.51 10.01 65 784767 17843 109786624
Hypotonia 18.47 10.01 54 784778 15691 109788776
Short stature 18.46 10.01 30 784802 1057 109803410
Swelling face 18.46 10.01 506 784326 91815 109712652
Vertigo 18.45 10.01 472 784360 86398 109718069
Malignant melanoma 18.32 10.01 192 784640 16699 109787768
Psychiatric decompensation 18.29 10.01 9 784823 5756 109798711
Brain injury 18.27 10.01 43 784789 13433 109791034
Breast feeding 18.18 10.01 24 784808 698 109803769
Erectile dysfunction 18.09 10.01 69 784763 18487 109785980
Pain in jaw 18.02 10.01 255 784577 50922 109753545
Congestive cardiomyopathy 18 10.01 47 784785 14172 109790295
Laryngeal oedema 18.00 10.01 26 784806 9781 109794686
Injection site bruising 17.98 10.01 484 784348 50779 109753688
Neurological symptom 17.97 10.01 54 784778 15554 109788913
Haematuria 17.90 10.01 450 784382 82555 109721912
Colitis ulcerative 17.90 10.01 695 784137 76668 109727799
Dyspepsia 17.87 10.01 1581 783251 189384 109615083
Porphyria acute 17.86 10.01 208 784624 18572 109785895
Depressive symptom 17.84 10.01 20 784812 8394 109796073
Cholangitis 17.76 10.01 58 784774 16277 109788190
Immune-mediated hepatitis 17.75 10.01 13 784819 6698 109797769
Hyperthyroidism 17.73 10.01 128 784704 29133 109775334
Pulmonary pain 17.73 10.01 90 784742 6203 109798264
Complications of transplanted kidney 17.71 10.01 16 784816 7426 109797041
Prostatic specific antigen increased 17.71 10.01 39 784793 12472 109791995
Eosinophil count increased 17.64 10.01 83 784749 20975 109783492
Polyhydramnios 17.61 10.01 41 784791 1892 109802575
Injection site warmth 17.56 10.01 195 784637 17210 109787257
Hypophagia 17.56 10.01 265 784567 52361 109752106
Neuritis 17.50 10.01 16 784816 7383 109797084
Disturbance in social behaviour 17.45 10.01 7 784825 5051 109799416
Intracranial pressure increased 17.37 10.01 30 784802 10505 109793962
Anhedonia 17.32 10.01 54 784778 15374 109789093
Long QT syndrome 17.30 10.01 15 784817 7103 109797364
Varicella zoster virus infection 17.28 10.01 12 784820 6356 109798111
Therapy interrupted 17.27 10.01 249 784583 49573 109754894
Hypervolaemia 17.21 10.01 247 784585 49213 109755254
Mucosal inflammation 17.20 10.01 535 784297 95606 109708861
Left ventricular dysfunction 17.19 10.01 97 784735 23396 109781071
Antibody test positive 17.19 10.01 55 784777 3065 109801402
Concomitant disease aggravated 17.18 10.01 59 784773 16305 109788162
Sudden death 17.17 10.01 102 784730 24293 109780174
Colitis microscopic 17.17 10.01 44 784788 13350 109791117
Methaemoglobinaemia 17.13 10.01 24 784808 9144 109795323
Pulmonary function test abnormal 17.12 10.01 7 784825 4993 109799474
Eosinophilic granulomatosis with polyangiitis 17.11 10.01 31 784801 10655 109793812
Placental disorder 17.10 10.01 28 784804 993 109803474
Eczema 16.95 10.01 387 784445 71906 109732561
Deep vein thrombosis 16.78 10.01 816 784016 139071 109665396
Nervous system disorder 16.78 10.01 144 784688 31577 109772890
Maternal exposure during breast feeding 16.74 10.01 67 784765 4171 109800296
Herpes zoster 16.74 10.01 935 783897 107444 109697023
Small for dates baby 16.66 10.01 22 784810 640 109803827
Cryptococcosis 16.66 10.01 6 784826 4625 109799842
Personality change 16.66 10.01 33 784799 10969 109793498
Brain natriuretic peptide increased 16.65 10.01 34 784798 11175 109793292
Metastases to lymph nodes 16.61 10.01 53 784779 14979 109789488
Pseudomonal sepsis 16.59 10.01 24 784808 9022 109795445
Hypertensive crisis 16.58 10.01 103 784729 24269 109780198
Cardiac septal defect 16.56 10.01 27 784805 954 109803513
Neutrophilia 16.50 10.01 30 784802 10299 109794168
Anticholinergic syndrome 16.35 10.01 5 784827 4275 109800192
Creatinine renal clearance increased 16.28 10.01 3 784829 3622 109800845
Electrolyte imbalance 16.24 10.01 176 784656 36852 109767615
Osteonecrosis 16.19 10.01 157 784675 33584 109770883
Tetany 16.15 10.01 3 784829 3601 109800866
Type I hypersensitivity 16.12 10.01 13 784819 6380 109798087
Endodontic procedure 16.12 10.01 54 784778 3082 109801385
Diaphragmatic disorder 16.09 10.01 39 784793 1847 109802620
Myoglobin blood increased 16.07 10.01 5 784827 4227 109800240
Activated partial thromboplastin time prolonged 16.02 10.01 93 784739 22275 109782192
Antineutrophil cytoplasmic antibody positive 15.99 10.01 8 784824 5068 109799399
Lower respiratory tract congestion 15.98 10.01 72 784760 4724 109799743
Treatment noncompliance 15.93 10.01 395 784437 72595 109731872
Post-traumatic stress disorder 15.91 10.01 14 784818 6582 109797885
Syringe issue 15.82 10.01 27 784805 9498 109794969
Benign ovarian tumour 15.81 10.01 18 784814 448 109804019
Mood altered 15.78 10.01 88 784744 21287 109783180
Stillbirth 15.73 10.01 66 784766 4198 109800269
Chronic obstructive pulmonary disease 15.72 10.01 624 784208 108534 109695933
Hepatitis C 15.58 10.01 42 784790 12531 109791936
Gait disturbance 15.55 10.01 2227 782605 275981 109528486
Breast cancer stage II 15.54 10.01 277 784555 27098 109777369
Blood glucose decreased 15.54 10.01 134 784698 29354 109775113
Foetal distress syndrome 15.52 10.01 21 784811 626 109803841
Incorrect dose administered 15.47 10.01 590 784242 103051 109701416
Catarrh 15.43 10.01 97 784735 7238 109797229
Swollen joint count 15.42 10.01 110 784722 8564 109795903
Staphylococcal infection 15.40 10.01 378 784454 69566 109734901
Device loosening 15.35 10.01 24 784808 818 109803649
Osteopenia 15.31 10.01 232 784600 21977 109782490
Hepatitis B 15.28 10.01 28 784804 9584 109794883
Radiation inflammation 15.25 10.01 27 784805 1021 109803446
Ear pain 15.25 10.01 490 784342 52736 109751731
Hyperventilation 15.19 10.01 25 784807 8922 109795545
Infection reactivation 15.18 10.01 5 784827 4076 109800391
Dyslipidaemia 15.16 10.01 60 784772 15905 109788562
Infusion site reaction 15.15 10.01 192 784640 17490 109786977
Device occlusion 15.11 10.01 56 784776 15129 109789338
Drug screen positive 14.99 10.01 14 784818 6396 109798071
Accidental overdose 14.99 10.01 268 784564 51566 109752901
Complication of device removal 14.98 10.01 7 784825 4613 109799854
Bone density increased 14.95 10.01 26 784806 969 109803498
Compartment syndrome 14.93 10.01 12 784820 5898 109798569
Hypertension 14.85 10.01 3952 780880 506132 109298335
Taste disorder 14.79 10.01 586 784246 64801 109739666
Haemorrhage in pregnancy 14.78 10.01 35 784797 1633 109802834
Atrial flutter 14.76 10.01 106 784726 24156 109780311
Extravascular haemolysis 14.74 10.01 17 784815 429 109804038
Total lung capacity increased 14.73 10.01 9 784823 5103 109799364
Eyelid oedema 14.72 10.01 57 784775 15205 109789262
Sickle cell anaemia 14.70 10.01 23 784809 784 109803683
Placental insufficiency 14.70 10.01 30 784802 1264 109803203
Extradural haematoma 14.68 10.01 3 784829 3366 109801101
Aspiration 14.68 10.01 142 784690 30391 109774076
Metabolic disorder 14.68 10.01 33 784799 10477 109793990
Plasma cell myeloma recurrent 14.65 10.01 17 784815 7025 109797442
Panic attack 14.59 10.01 133 784699 28807 109775660
Anal fissure 14.59 10.01 120 784712 9761 109794706
Cushingoid 14.58 10.01 137 784695 11575 109792892
Nail injury 14.58 10.01 23 784809 790 109803677
Clostridium test positive 14.57 10.01 35 784797 10858 109793609
Genital haemorrhage 14.56 10.01 18 784814 7234 109797233
Ligament rupture 14.53 10.01 62 784770 3973 109800494
Impaired gastric emptying 14.53 10.01 47 784785 13228 109791239
Intraocular pressure increased 14.51 10.01 35 784797 10841 109793626
Cyst 14.51 10.01 180 784652 16316 109788151
Injection site swelling 14.51 10.01 556 784276 61234 109743233
Epstein-Barr virus associated lymphoproliferative disorder 14.49 10.01 8 784824 4794 109799673
Pharyngeal swelling 14.31 10.01 41 784791 11991 109792476
Insurance issue 14.27 10.01 34 784798 10578 109793889
Asthenia 14.27 10.01 4522 780310 684477 109119990
Hypoglycaemic coma 14.27 10.01 11 784821 5522 109798945
Autonomic nervous system imbalance 14.27 10.01 12 784820 5768 109798699
Bronchial secretion retention 14.27 10.01 9 784823 5015 109799452
Head injury 14.22 10.01 217 784615 42800 109761667
Haematocrit decreased 14.14 10.01 589 784243 65528 109738939
Central nervous system mass 14.14 10.01 23 784809 811 109803656
Steroid diabetes 14.13 10.01 10 784822 5244 109799223
Bone density abnormal 14.08 10.01 60 784772 3843 109800624
Oral candidiasis 14.05 10.01 228 784604 44532 109759935
Extra dose administered 14.05 10.01 42 784790 12117 109792350
Hepatic cancer 14.03 10.01 37 784795 11119 109793348
Injection site rash 14.03 10.01 239 784593 23180 109781287
Neoplasm recurrence 14.01 10.01 10 784822 5222 109799245
Epstein-Barr viraemia 14.01 10.01 4 784828 3575 109800892
Wall motion score index abnormal 14.00 10.01 23 784809 818 109803649
Hepatic necrosis 13.98 10.01 31 784801 9891 109794576
Spinal osteoarthritis 13.97 10.01 211 784621 19972 109784495
Retinal haemorrhage 13.96 10.01 29 784803 9472 109794995
Nervousness 13.92 10.01 181 784651 36670 109767797
Mitochondrial toxicity 13.92 10.01 3 784829 3242 109801225
Enterococcal infection 13.89 10.01 86 784746 20280 109784187
Staphylococcal bacteraemia 13.84 10.01 66 784766 16622 109787845
Back pain 13.84 10.01 2368 782464 368628 109435839
Coeliac disease 13.82 10.01 403 784429 42784 109761683
Blood potassium increased 13.81 10.01 160 784672 33089 109771378
Pancreatic steatosis 13.79 10.01 36 784796 1786 109802681
Bradyarrhythmia 13.79 10.01 9 784823 4925 109799542
Lymph gland infection 13.79 10.01 20 784812 637 109803830
Lacrimal disorder 13.78 10.01 18 784814 518 109803949
Mental impairment 13.73 10.01 99 784733 22540 109781927
Blood folate increased 13.72 10.01 19 784813 579 109803888
Multiple allergies 13.71 10.01 43 784789 12220 109792247
Behaviour disorder 13.71 10.01 30 784802 9617 109794850
Cytomegalovirus colitis 13.68 10.01 18 784814 7043 109797424
Induced labour 13.64 10.01 24 784808 903 109803564
Accidental exposure to product by child 13.63 10.01 3 784829 3195 109801272
Heart rate irregular 13.61 10.01 329 784503 33945 109770522
Hypovolaemia 13.53 10.01 94 784738 21580 109782887
Cervical incompetence 13.50 10.01 18 784814 529 109803938
Obsessive-compulsive disorder 13.48 10.01 19 784813 7222 109797245
Corneal oedema 13.47 10.01 3 784829 3170 109801297
Gastric cancer 13.47 10.01 37 784795 10971 109793496
Bone marrow failure 13.47 10.01 310 784522 57538 109746929
Iritis 13.43 10.01 67 784765 4585 109799882
Immune thrombocytopenia 13.34 10.01 99 784733 22395 109782072
Hypoventilation 13.34 10.01 23 784809 8058 109796409
Acute lung injury 13.34 10.01 3 784829 3148 109801319
Cyst rupture 13.33 10.01 23 784809 852 109803615
Hand fracture 13.29 10.01 101 784731 8021 109796446
Wrong product administered 13.29 10.01 37 784795 10923 109793544
Cerebral toxoplasmosis 13.28 10.01 3 784829 3139 109801328
Vasculitis 13.25 10.01 177 784655 35696 109768771
Troponin T increased 13.24 10.01 7 784825 4299 109800168
Vein disorder 13.24 10.01 83 784749 6187 109798280
Hallucinations, mixed 13.23 10.01 26 784806 8667 109795800
Lower gastrointestinal haemorrhage 13.16 10.01 77 784755 18409 109786058
Lip oedema 13.13 10.01 21 784811 7579 109796888
Respiratory tract infection 13.12 10.01 628 784204 70989 109733478
Pneumonia fungal 13.05 10.01 57 784775 14697 109789770
Drooling 13.03 10.01 19 784813 7120 109797347
Renal cancer 13.01 10.01 48 784784 12986 109791481
Bronchopulmonary aspergillosis allergic 13.00 10.01 25 784807 8401 109796066
Delayed graft function 12.98 10.01 7 784825 4250 109800217
Cardiac dysfunction 12.97 10.01 15 784817 6208 109798259
Pain of skin 12.93 10.01 86 784746 19943 109784524
Medication error 12.93 10.01 891 783941 104475 109699992
Spinal cord compression 12.92 10.01 21 784811 7531 109796936
Granulocyte count decreased 12.92 10.01 6 784826 3968 109800499
Reversible cerebral vasoconstriction syndrome 12.88 10.01 9 784823 4752 109799715
Blood loss anaemia 12.88 10.01 75 784757 17950 109786517
Sneezing 12.86 10.01 155 784677 31829 109772638
Nightmare 12.86 10.01 196 784636 38667 109765800
Abortion incomplete 12.85 10.01 3 784829 3069 109801398
Mitral valve incompetence 12.84 10.01 163 784669 33166 109771301
Joint lock 12.82 10.01 55 784777 3533 109800934
Tumour haemorrhage 12.81 10.01 11 784821 5234 109799233
Pseudomembranous colitis 12.69 10.01 16 784816 6375 109798092
Injection site extravasation 12.69 10.01 119 784713 10050 109794417
Nystagmus 12.66 10.01 41 784791 11536 109792931
Upper gastrointestinal haemorrhage 12.66 10.01 265 784567 49831 109754636
Kounis syndrome 12.65 10.01 14 784818 5911 109798556
Blood uric acid increased 12.65 10.01 95 784737 21434 109783033
Transient aphasia 12.63 10.01 20 784812 689 109803778
Dysuria 12.59 10.01 328 784504 59903 109744564
Defaecation disorder 12.59 10.01 22 784810 823 109803644
Anger 12.58 10.01 81 784751 18926 109785541
Plasma cell myeloma 12.57 10.01 345 784487 62591 109741876
Burns second degree 12.56 10.01 96 784736 7637 109796830
Swollen tongue 12.55 10.01 329 784503 60033 109744434
Oligoarthritis 12.52 10.01 21 784811 760 109803707
Secondary adrenocortical insufficiency 12.51 10.01 8 784824 4426 109800041
Nephrotic syndrome 12.50 10.01 53 784779 13778 109790689
Human anti-human antibody test 12.48 10.01 15 784817 396 109804071
Lymphoedema 12.41 10.01 59 784773 14870 109789597
Musculoskeletal disorder 12.40 10.01 228 784604 22436 109782031
Renal tubular disorder 12.39 10.01 21 784811 7408 109797059
Areflexia 12.37 10.01 18 784814 6751 109797716
Fungaemia 12.33 10.01 15 784817 6071 109798396
C-reactive protein decreased 12.31 10.01 47 784785 2862 109801605
Hypopituitarism 12.28 10.01 8 784824 4382 109800085
Urinary incontinence 12.28 10.01 257 784575 48330 109756137
Tender joint count increased 12.28 10.01 15 784817 403 109804064
Dactylitis 12.27 10.01 60 784772 4073 109800394
Cough 12.21 10.01 2998 781834 458643 109345824
Complication of device insertion 12.14 10.01 28 784804 8810 109795657
Viraemia 12.14 10.01 7 784825 4095 109800372
Threatened labour 12.12 10.01 19 784813 649 109803818
Enterobacter infection 12.12 10.01 14 784818 5797 109798670
Airway remodelling 12.10 10.01 23 784809 919 109803548
Ataxia 12.07 10.01 146 784686 29962 109774505
Hypertonia 12.06 10.01 26 784806 8380 109796087
Rhinovirus infection 12.04 10.01 43 784789 11746 109792721
Frequent bowel movements 12.04 10.01 621 784211 70769 109733698
Epstein-Barr virus infection reactivation 12.04 10.01 7 784825 4077 109800390
Crying 11.98 10.01 120 784712 25508 109778959
Productive cough 11.96 10.01 676 784156 113629 109690838
Dermatitis bullous 11.96 10.01 74 784758 17455 109787012
Wrong patient received product 11.95 10.01 18 784814 6656 109797811
Leukoencephalopathy 11.94 10.01 30 784802 9165 109795302
Fanconi syndrome 11.93 10.01 5 784827 3514 109800953
Post procedural haemorrhage 11.93 10.01 63 784769 15449 109789018
Liver abscess 11.90 10.01 23 784809 7716 109796751
Bone fissure 11.89 10.01 18 784814 596 109803871
Ulcer 11.85 10.01 395 784437 42721 109761746
Dermatitis exfoliative 11.85 10.01 41 784791 11306 109793161
Vascular purpura 11.79 10.01 6 784826 3765 109800702
Pneumomediastinum 11.78 10.01 11 784821 5025 109799442
Labyrinthitis 11.77 10.01 48 784784 3014 109801453
Breast cancer female 11.75 10.01 47 784785 12421 109792046
Joint warmth 11.74 10.01 37 784795 2045 109802422
Cardiopulmonary failure 11.72 10.01 24 784808 7879 109796588
Product monitoring error 11.69 10.01 29 784803 8898 109795569
Device breakage 11.69 10.01 54 784778 13715 109790752
Parvovirus B19 infection 11.69 10.01 3 784829 2878 109801589
Sleep disorder therapy 11.67 10.01 22 784810 7449 109797018
Pupillary reflex impaired 11.67 10.01 7 784825 4008 109800459
Immunisation 11.67 10.01 4 784828 3179 109801288
Clonus 11.66 10.01 28 784804 8688 109795779
Oxygen saturation decreased 11.66 10.01 1279 783553 155703 109648764
Carcinoid tumour of the small bowel 11.66 10.01 15 784817 425 109804042
Infusion site pain 11.65 10.01 74 784758 17345 109787122
Paronychia 11.60 10.01 40 784792 11041 109793426
Skin weeping 11.59 10.01 6 784826 3729 109800738
Poor quality device used 11.58 10.01 3 784829 2860 109801607
Arteriospasm coronary 11.58 10.01 30 784802 9070 109795397
Oesophageal fibrosis 11.57 10.01 10 784822 176 109804291
Arteriosclerosis 11.56 10.01 116 784716 24651 109779816
Hyporesponsive to stimuli 11.56 10.01 3 784829 2857 109801610
Embolism 11.52 10.01 68 784764 16221 109788246
Osteoporotic fracture 11.49 10.01 71 784761 5266 109799201
Hypothalamo-pituitary disorder 11.48 10.01 3 784829 2843 109801624
Product dose omission in error 11.45 10.01 109 784723 23403 109781064
Terminal state 11.45 10.01 14 784818 5653 109798814
Brain abscess 11.44 10.01 19 784813 6755 109797712
Increased appetite 11.42 10.01 61 784771 14916 109789551
Uveitis 11.39 10.01 217 784615 21493 109782974
Schizoaffective disorder 11.39 10.01 4 784828 3132 109801335
Cogwheel rigidity 11.39 10.01 6 784826 3692 109800775
Aphthous ulcer 11.35 10.01 212 784620 20924 109783543
Quadriparesis 11.34 10.01 10 784822 4697 109799770
Tooth disorder 11.34 10.01 282 784550 29227 109775240
Prerenal failure 11.33 10.01 9 784823 4450 109800017
Drug abuser 11.31 10.01 13 784819 5396 109799071
Pharyngitis streptococcal 11.30 10.01 144 784688 13133 109791334
Feeding disorder 11.29 10.01 97 784735 21265 109783202
Skin necrosis 11.28 10.01 215 784617 21297 109783170
Tension headache 11.27 10.01 33 784799 9585 109794882
Choking 11.27 10.01 62 784770 15048 109789419
Alcohol abuse 11.26 10.01 11 784821 4918 109799549
Muscle spasticity 11.26 10.01 183 784649 35732 109768735
Myofascial pain syndrome 11.24 10.01 42 784790 2531 109801936
Clear cell renal cell carcinoma 11.23 10.01 44 784788 2712 109801755
Cold sweat 11.22 10.01 101 784731 21930 109782537
Cystoid macular oedema 11.20 10.01 3 784829 2797 109801670
Liver transplant rejection 11.15 10.01 7 784825 3911 109800556
Erythema of eyelid 11.13 10.01 7 784825 3908 109800559
Pneumonitis 11.13 10.01 437 784395 76094 109728373
Fibroadenoma of breast 11.08 10.01 19 784813 700 109803767
Rash morbilliform 11.08 10.01 25 784807 7926 109796541
Cardiac tamponade 11.05 10.01 42 784790 11265 109793202
Tubulointerstitial nephritis 10.99 10.01 297 784535 53987 109750480
Abortion threatened 10.96 10.01 15 784817 452 109804015
Eye movement disorder 10.96 10.01 34 784798 9694 109794773
Hypochloraemia 10.95 10.01 6 784826 3612 109800855
Mycobacterium chelonae infection 10.95 10.01 4 784828 3056 109801411
Subileus 10.92 10.01 18 784814 6419 109798048
Autoimmune hepatitis 10.90 10.01 61 784771 14743 109789724
Anaesthetic complication 10.89 10.01 6 784826 3600 109800867
Haemorrhage subcutaneous 10.86 10.01 14 784818 5525 109798942
Skin graft failure 10.84 10.01 11 784821 239 109804228
Thirst 10.84 10.01 100 784732 21607 109782860
Inadequate analgesia 10.84 10.01 12 784820 5065 109799402
Haemorrhagic transformation stroke 10.82 10.01 4 784828 3033 109801434
Breast abscess 10.81 10.01 32 784800 1709 109802758
Knee operation 10.76 10.01 86 784746 6936 109797531
Blood phosphorus decreased 10.76 10.01 24 784808 7641 109796826
Tumour marker increased 10.76 10.01 12 784820 5048 109799419
Lung transplant 10.74 10.01 13 784819 5273 109799194
Disorganised speech 10.72 10.01 5 784827 3298 109801169
Neutrophil count increased 10.72 10.01 177 784655 34475 109769992
Tuberculin test positive 10.72 10.01 53 784779 3615 109800852
Throat tightness 10.71 10.01 170 784662 33319 109771148
Oculogyric crisis 10.70 10.01 7 784825 3825 109800642
Brain herniation 10.69 10.01 30 784802 8833 109795634
Hypoproteinaemia 10.68 10.01 16 784816 5929 109798538
Malnutrition 10.67 10.01 133 784699 27146 109777321
Peritoneal dialysis complication 10.66 10.01 41 784791 2505 109801962
Twin pregnancy 10.63 10.01 22 784810 936 109803531
Impaired work ability 10.61 10.01 254 784578 26165 109778302
Lip and/or oral cavity cancer 10.58 10.01 25 784807 1165 109803302
Pancreatic carcinoma 10.56 10.01 62 784770 14810 109789657
Apraxia 10.53 10.01 6 784826 3534 109800933
Cancer pain 10.53 10.01 20 784812 6752 109797715
Injection site haemorrhage 10.51 10.01 308 784524 32720 109771747
Device issue 10.48 10.01 177 784655 34358 109770109
Renal disorder 10.46 10.01 269 784563 49210 109755257
CD4 lymphocytes decreased 10.45 10.01 4 784828 2970 109801497
Middle insomnia 10.43 10.01 94 784738 20408 109784059
Lip blister 10.40 10.01 49 784783 3276 109801191
Catatonia 10.40 10.01 43 784789 11257 109793210
Angina unstable 10.39 10.01 71 784761 16361 109788106
Candida sepsis 10.38 10.01 4 784828 2957 109801510
Hospitalisation 10.37 10.01 870 783962 141623 109662844
Swollen joint count decreased 10.34 10.01 13 784819 360 109804107
Tonic clonic movements 10.33 10.01 4 784828 2948 109801519
Vertebral osteophyte 10.32 10.01 16 784816 541 109803926
Mesothelioma 10.31 10.01 13 784819 361 109804106
Immune-mediated myocarditis 10.30 10.01 6 784826 3492 109800975
Persecutory delusion 10.30 10.01 18 784814 6273 109798194
Joint ankylosis 10.29 10.01 40 784792 2457 109802010
Tooth abscess 10.27 10.01 189 784643 18600 109785867
Abortion missed 10.27 10.01 29 784803 1508 109802959
Staphylococcal sepsis 10.26 10.01 77 784755 17377 109787090
Vacuum extractor delivery 10.26 10.01 8 784824 121 109804346
Hypovolaemic shock 10.25 10.01 61 784771 14522 109789945
Post procedural haematoma 10.23 10.01 3 784829 2636 109801831
Resuscitation 10.22 10.01 4 784828 2929 109801538
Hereditary angioedema 10.21 10.01 22 784810 7092 109797375
Nasal obstruction 10.21 10.01 49 784783 3301 109801166
Gastric ulcer haemorrhage 10.19 10.01 37 784795 10057 109794410
Pancreatitis 10.18 10.01 551 784281 92982 109711485
Hepatitis E antibody positive 10.17 10.01 11 784821 258 109804209
Apnoea 10.15 10.01 56 784776 13583 109790884
Analgesic therapy 10.07 10.01 23 784809 7261 109797206
Transfusion-related circulatory overload 10.05 10.01 21 784811 900 109803567
Unevaluable event 10.01 10.01 332 784500 58895 109745572

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

SourceCodeDescription
CHEBI has role CHEBI:75835 anti-anaemic agent

Drug Use | Suggest Off label Use Form| |View source of the data|

None




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

None

Orange Book patent data (new drug applications)

Formulation strengthTrade nameApplicantApplication numberApproval dateTypeDose formRoutePatent numberPatent expiration datePatent use
EQ 0.3MG COPPER/ML;EQ 55MCG BASE/ML;EQ 60MCG SELENIUM/ML;EQ 3MG BASE/ML (1ML) TRALEMENT AM REGENT N209376 July 2, 2020 RX SOLUTION INTRAVENOUS 11975022 July 1, 2041 ADULT AND PEDIATRIC PATIENTS WEIGHING AT LEAST 10 KG AS A SOURCE OF ZINC, COPPER, MANGANESE, AND SELENIUM FOR PARENTERAL NUTRITION WHEN ORAL OR ENTERAL NUTRITION IS NOT POSSIBLE, INSUFFICIENT, OR CONTRAINDICATED
EQ 0.3MG COPPER/ML;EQ 55MCG BASE/ML;EQ 60MCG SELENIUM/ML;EQ 3MG BASE/ML (1ML) TRALEMENT AM REGENT N209376 July 2, 2020 RX SOLUTION INTRAVENOUS 12150956 July 1, 2041 ADULT AND PEDIATRIC PATIENTS WEIGHING AT LEAST 10 KG AS A SOURCE OF ZINC, COPPER, MANGANESE, AND SELENIUM FOR PARENTERAL NUTRITION WHEN ORAL OR ENTERAL NUTRITION IS NOT POSSIBLE, INSUFFICIENT, OR CONTRAINDICATED
EQ 0.3MG COPPER/ML;EQ 55MCG BASE/ML;EQ 60MCG SELENIUM/ML;EQ 3MG BASE/ML (1ML) TRALEMENT AM REGENT N209376 July 2, 2020 RX SOLUTION INTRAVENOUS 12150957 July 1, 2041 ADULT AND PEDIATRIC PATIENTS WEIGHING AT LEAST 10 KG AS A SOURCE OF ZINC, COPPER, MANGANESE, AND SELENIUM FOR PARENTERAL NUTRITION WHEN ORAL OR ENTERAL NUTRITION IS NOT POSSIBLE, INSUFFICIENT, OR CONTRAINDICATED
EQ 0.3MG COPPER/ML;EQ 55MCG BASE/ML;EQ 60MCG SELENIUM/ML;EQ 3MG BASE/ML (5ML) TRALEMENT AM REGENT N209376 Dec. 2, 2020 RX SOLUTION INTRAVENOUS 11975022 July 1, 2041 ADULT AND PEDIATRIC PATIENTS WEIGHING AT LEAST 10 KG AS A SOURCE OF ZINC, COPPER, MANGANESE, AND SELENIUM FOR PARENTERAL NUTRITION WHEN ORAL OR ENTERAL NUTRITION IS NOT POSSIBLE, INSUFFICIENT, OR CONTRAINDICATED
EQ 0.3MG COPPER/ML;EQ 55MCG BASE/ML;EQ 60MCG SELENIUM/ML;EQ 3MG BASE/ML (5ML) TRALEMENT AM REGENT N209376 Dec. 2, 2020 RX SOLUTION INTRAVENOUS 12150956 July 1, 2041 ADULT AND PEDIATRIC PATIENTS WEIGHING AT LEAST 10 KG AS A SOURCE OF ZINC, COPPER, MANGANESE, AND SELENIUM FOR PARENTERAL NUTRITION WHEN ORAL OR ENTERAL NUTRITION IS NOT POSSIBLE, INSUFFICIENT, OR CONTRAINDICATED
EQ 0.3MG COPPER/ML;EQ 55MCG BASE/ML;EQ 60MCG SELENIUM/ML;EQ 3MG BASE/ML (5ML) TRALEMENT AM REGENT N209376 Dec. 2, 2020 RX SOLUTION INTRAVENOUS 12150957 July 1, 2041 ADULT AND PEDIATRIC PATIENTS WEIGHING AT LEAST 10 KG AS A SOURCE OF ZINC, COPPER, MANGANESE, AND SELENIUM FOR PARENTERAL NUTRITION WHEN ORAL OR ENTERAL NUTRITION IS NOT POSSIBLE, INSUFFICIENT, OR CONTRAINDICATED
EQ 60MCG COPPER/ML;EQ 3MCG BASE/ML;EQ 6MCG SELENIUM/ML;EQ 1000MCG BASE/ML (1ML) MULTRYS AM REGENT N209376 June 30, 2021 RX SOLUTION INTRAVENOUS 11975022 July 1, 2041 NEONATAL AND PEDIATRIC PATIENTS WEIGHING LESS THAN 10 KG AS A SOURCE OF ZINC, COPPER, MANGANESE, AND SELENIUM FOR PARENTERAL NUTRITION WHEN ORAL OR ENTERAL NUTRITION IS NOT POSSIBLE, INSUFFICIENT, OR CONTRAINDICATED
EQ 60MCG COPPER/ML;EQ 3MCG BASE/ML;EQ 6MCG SELENIUM/ML;EQ 1000MCG BASE/ML (1ML) MULTRYS AM REGENT N209376 June 30, 2021 RX SOLUTION INTRAVENOUS 12150956 July 1, 2041 NEONATAL AND PEDIATRIC PATIENTS WEIGHING LESS THAN 10 KG AS A SOURCE OF ZINC, COPPER, MANGANESE, AND SELENIUM FOR PARENTERAL NUTRITION WHEN ORAL OR ENTERAL NUTRITION IS NOT POSSIBLE, INSUFFICIENT, OR CONTRAINDICATED
EQ 60MCG COPPER/ML;EQ 3MCG BASE/ML;EQ 6MCG SELENIUM/ML;EQ 1000MCG BASE/ML (1ML) MULTRYS AM REGENT N209376 June 30, 2021 RX SOLUTION INTRAVENOUS 12150957 July 1, 2041 NEONATAL AND PEDIATRIC PATIENTS WEIGHING LESS THAN 10 KG AS A SOURCE OF ZINC, COPPER, MANGANESE, AND SELENIUM FOR PARENTERAL NUTRITION WHEN ORAL OR ENTERAL NUTRITION IS NOT POSSIBLE, INSUFFICIENT, OR CONTRAINDICATED

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

IDSource
D04854 KEGG_DRUG
4017709 VUID
N0000179176 NUI
10034-96-5 SECONDARY_CAS_RN
4017681 VANDF
4017709 VANDF
CHEBI:86364 CHEBI
CHEMBL2103742 ChEMBL_ID
C039798 MESH_SUPPLEMENTAL_RECORD_UI
W00LYS4T26 UNII
24580 PUBCHEM_CID
29268 RXNORM
1544 MMSL
33690 MMSL
5021 MMSL
d00434 MMSL
000858 NDDF
C0065649 UMLSCUI
W00LYS4T26 INXIGHT DRUGS

Pharmaceutical products:

ProductCategoryIngredientsNDCFormQuantityRouteMarketingLabel
Multitrace-5 HUMAN PRESCRIPTION DRUG LABEL 5 0517-8510 INJECTION, SOLUTION 0.31 mg INTRAVENOUS UNAPPROVED DRUG OTHER 14 sections
Multitrace -4 Pediatric HUMAN PRESCRIPTION DRUG LABEL 4 0517-9203 INJECTION, SOLUTION, CONCENTRATE 77 ug INTRAVENOUS UNAPPROVED DRUG OTHER 14 sections
Multrys HUMAN PRESCRIPTION DRUG LABEL 4 0517-9302 INJECTION, SOLUTION 8.22 ug INTRAVENOUS NDA 19 sections
Tralement HUMAN PRESCRIPTION DRUG LABEL 4 0517-9305 INJECTION, SOLUTION 55 ug INTRAVENOUS NDA 22 sections
Se-Tan PLUS HUMAN PRESCRIPTION DRUG LABEL 13 13925-118 CAPSULE, GELATIN COATED 1.30 mg ORAL unapproved drug other 18 sections
Centratex HUMAN PRESCRIPTION DRUG LABEL 13 23359-100 CAPSULE 1.30 mg ORAL unapproved drug other 13 sections
Concept OB HUMAN PRESCRIPTION DRUG LABEL 15 52747-620 CAPSULE 1.30 mg ORAL unapproved drug other 13 sections
Multitol-M HUMAN PRESCRIPTION DRUG LABEL 17 59088-005 TABLET 2.30 mg ORAL unapproved drug other 11 sections
Finazol HUMAN PRESCRIPTION DRUG LABEL 24 59088-008 TABLET 0.75 mg ORAL unapproved drug other 13 sections
Prenatol-M HUMAN PRESCRIPTION DRUG LABEL 20 59088-009 TABLET 2.60 mg ORAL unapproved drug other 13 sections
PureVit DualFe Plus HUMAN PRESCRIPTION DRUG LABEL 13 59088-112 CAPSULE 1.30 mg ORAL unapproved drug other 12 sections
Vitalux HUMAN PRESCRIPTION DRUG LABEL 20 59088-139 TABLET 2.60 mg ORAL unapproved drug other 13 sections
Vitrexyl HUMAN PRESCRIPTION DRUG LABEL 17 59088-164 TABLET 2.30 mg ORAL unapproved drug other 11 sections
Vitrexyl plus Iron HUMAN PRESCRIPTION DRUG LABEL 18 59088-165 TABLET 2.30 mg ORAL unapproved drug other 13 sections
Prenatrix HUMAN PRESCRIPTION DRUG LABEL 20 59088-166 TABLET 2.60 mg ORAL unapproved drug other 13 sections
Vitrexate HUMAN PRESCRIPTION DRUG LABEL 17 59088-167 TABLET 2.30 mg ORAL unapproved drug other 11 sections
Vitrexate FE HUMAN PRESCRIPTION DRUG LABEL 18 59088-168 TABLET 2.30 mg ORAL unapproved drug other 13 sections
Prenatryl HUMAN PRESCRIPTION DRUG LABEL 20 59088-169 TABLET 2.60 mg ORAL unapproved drug other 13 sections
Vitranol HUMAN PRESCRIPTION DRUG LABEL 17 59088-171 TABLET 2.30 mg ORAL unapproved drug other 11 sections
Prometa HUMAN PRESCRIPTION DRUG LABEL 20 59088-172 TABLET 2.60 mg ORAL unapproved drug other 13 sections
Vitranol Fe HUMAN PRESCRIPTION DRUG LABEL 18 59088-173 TABLET 2.30 mg ORAL unapproved drug other 13 sections
Venexa HUMAN PRESCRIPTION DRUG LABEL 17 59088-176 TABLET 2.30 mg ORAL unapproved drug other 11 sections
Venexa FE HUMAN PRESCRIPTION DRUG LABEL 18 59088-177 TABLET 2.30 mg ORAL unapproved drug other 13 sections
Pretrate HUMAN PRESCRIPTION DRUG LABEL 20 59088-178 TABLET 2.60 mg ORAL unapproved drug other 13 sections
Zintrexyl-C HUMAN PRESCRIPTION DRUG LABEL 24 59088-180 TABLET 0.75 mg ORAL unapproved drug other 13 sections
Folitin-Z HUMAN PRESCRIPTION DRUG LABEL 24 59088-181 TABLET 0.75 mg ORAL unapproved drug other 13 sections
Ribotin-E HUMAN PRESCRIPTION DRUG LABEL 24 59088-182 TABLET 0.75 mg ORAL unapproved drug other 13 sections
Ventrixyl HUMAN PRESCRIPTION DRUG LABEL 17 59088-186 TABLET 2.30 mg ORAL unapproved drug other 12 sections
Ventrixyl Fe HUMAN PRESCRIPTION DRUG LABEL 18 59088-187 TABLET 2.30 mg ORAL unapproved drug other 13 sections
Vitramyn HUMAN PRESCRIPTION DRUG LABEL 17 59088-193 TABLET 2.30 mg ORAL unapproved drug other 11 sections