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decamethrin 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | PK/Tox | Related Drugs | BioActivity |
| Stem definition | Drug id | CAS RN |
|---|---|---|
| 4378 | 52918-63-5 |
Description:
| Molecule | Description |
|---|---|
|
Synonyms:
|
A synthetic pyrethroid insecticide with contact and residual activity, also used as an acaricide.
|
Drug dosage:
None
ADMET properties:
None
Predicted pharmacokinetic/toxicological properties (PK-AZ):
| Property | Description | Value | Unit | Confidence | Similarity |
|---|---|---|---|---|---|
| kinase-safety-class | ACVR2A,ACVR2B,AKT2,AKT3,AURKA,AXL,BRAF,BTK,CAMK2B,CAMK2D,CDK5,CDK9,DDR1,DYRK1B,EGFR,EIF2AK3,EPHB4,ERBB2,GRK2,GSK3B,ITK,JAK2,JAK3,MAP2K6,MAP3K1,MAP3K21,MAP3K7,MAPK10,MAPK12,MAPK7,MAPK9,MAPKAPK2,MARK4,MET,MTOR,NTRK2,PDK1,PDK2,PDK4,PDPK1,PIK3CB,PIK3CD,PIK3CG,PIM2,PRKCD,PRKDC,SIK2,SIK3,STK33,SYK,TEK,TTK,ULK1,ZAP70 | 54 | |||
| kinase-selectivity-class | AXL,GRK2,PIK3CB,RIPK1 | 4 | |||
| pfas-class | PFAS structural alert (1 = True, 0 = False) | 0 |
Approvals:
None
FDA Adverse Event Reporting System (Female)
None
FDA Adverse Event Reporting System (Male)
None
FDA Adverse Event Reporting System (Geriatric)
None
FDA Adverse Event Reporting System (Pediatric)
None
Pharmacologic Action:
| Source | Code | Description |
|---|---|---|
| ATC | P03BA03 | ANTIPARASITIC PRODUCTS, INSECTICIDES AND REPELLENTS ECTOPARASITICIDES, INCL. SCABICIDES, INSECTICIDES AND REPELLENTS INSECTICIDES AND REPELLENTS Pyrethrines |
| MeSH PA | D007306 | Insecticides |
| MeSH PA | D010575 | Pesticides |
| CHEBI has role | CHEBI:22583 | antifeedant |
| CHEBI has role | CHEBI:33286 | agrochemical |
| CHEBI has role | CHEBI:35442 | antiparasitic agent |
| CHEBI has role | CHEBI:37153 | EC 3.1.3.16 (phosphoprotein phosphatase) inhibitor |
| CHEBI has role | CHEBI:38807 | calcium channel agonist |
| CHEBI has role | CHEBI:39116 | pyrethroid ester insecticide |
Related Drugs by ATC class:
P03BA Pyrethrines 3 drugs
Drug Use | Suggest Off label Use Form| |View source of the data|
None
🐶 Veterinary Drug Use
None
🐶 Veterinary products
None
Acid dissociation constants calculated using MoKa v3.0.0
None
Orange Book patent data (new drug applications)
None
Orange Book exclusivity data (new drug applications)
None
Bioactivity Summary:
None
External reference:
| ID | Source |
|---|---|
| D07785 | KEGG_DRUG |
| C0057233 | UMLSCUI |
| CHEBI:4388 | CHEBI |
| CHEMBL1593566 | ChEMBL_ID |
| DB13600 | DRUGBANK_ID |
| C017180 | MESH_SUPPLEMENTAL_RECORD_UI |
| 40585 | PUBCHEM_CID |
| 22374 | RXNORM |
| 004346 | NDDF |
| 2JTS8R821G | UNII |
| 2JTS8R821G | INXIGHT DRUGS |
Pharmaceutical products:
None