DrugCentral 2023 🐕
2022 Update-Veterinary Drugs & Uses
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DrugCentral 2023 🐕
2022 Update-Veterinary Drugs & Uses
Search
Structure 🔎
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L1000
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Substructure SMILES Example:
n1cnccc1
xantinol 🐶
Veterinary Use |
Indications/Contra
| FAERs-F
| FAERs-M
| Orange Bk
| BioActivity |
Stem definition
Drug id
CAS RN
N-methylated xanthine derivatives
4368
437-74-1
Description:
Molecule
Description
Molfile
Inchi
Smiles
Synonyms:
xanthinol
xantinol
xantinol nicotinate
xanthinol nicotinate
xanthinol niacinate
A vasodilator used in peripheral vascular disorders and insufficiency. It may cause gastric discomfort and hypotension.
Molecular weight: 311.34
Formula: C13H21N5O4
CLOGP: -1.14
LIPINSKI: 0
HAC: 9
HDO: 2
TPSA: 102.14
ALOGS: -1.25
ROTB: 6
Drug dosage:
Dose
Unit
Route
0.90
g
O
0.90
g
P
ADMET properties:
None
Approvals:
None
FDA Adverse Event Reporting System (Female)
None
FDA Adverse Event Reporting System (Male)
None
FDA Adverse Event Reporting System (Geriatric)
None
FDA Adverse Event Reporting System (Pediatric)
None
Pharmacologic Action:
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Source
Code
Description
ATC
C04AD02
CARDIOVASCULAR SYSTEM
PERIPHERAL VASODILATORS
PERIPHERAL VASODILATORS
Purine derivatives
CHEBI has role
CHEBI:25212
metabolites
CHEBI has role
CHEBI:35620
vasodilator agents
CHEBI has role
CHEBI:35679
antilipemic drugs
CHEBI has role
CHEBI:50247
antidotes
CHEBI has role
CHEBI:75771
Mus musculus metabolites
CHEBI has role
CHEBI:76924
plant metabolites
CHEBI has role
CHEBI:76971
Escherichia coli metabolites
CHEBI has role
CHEBI:84087
human urinary metabolites
CHEBI has role
CHEBI:84264
nicotinamide deaminase inhibitors
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Drug Use
| Suggest Off label Use Form|
|View source of the data|
None
🐶 Veterinary Drug Use
None
🐶 Veterinary products
None
Acid dissociation constants calculated using MoKa v3.0.0
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Dissociation level
Dissociation constant
Type (acidic/basic)
pKa1
13.25
acidic
pKa2
7.86
Basic
pKa3
1.66
Basic
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Orange Book patent data (new drug applications)
None
Orange Book exclusivity data (new drug applications)
None
Bioactivity Summary:
None
External reference:
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ID
Source
NIO
PDB_CHEM_ID
001052
NDDF
003508
NDDF
10500003
SNOMEDCT_US
11358
RXNORM
1492
INN_ID
2275
MMSL
2530-97-4
SECONDARY_CAS_RN
273943001
SNOMEDCT_US
4017661
VANDF
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Pharmaceutical products:
None
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xantinol