zinc gluconate 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definition	Drug id	CAS RN
	4343	4468-02-4

Description:

Molecule	Description
Synonyms: zinc gluconate trihydrate zinc gluconate	zinc gluconate has anti-inflammatory activity; RN given refers to (D)-isomer; all RRs refers to (D)-isomer unless otherwise noted Molecular weight: 455.67 Formula: C12H22O14Zn CLOGP: LIPINSKI: None HAC: None HDO: None TPSA: 141.28 ALOGS: ROTB: None

Molecule

Description

Synonyms:

zinc gluconate trihydrate
zinc gluconate

zinc gluconate has anti-inflammatory activity; RN given refers to (D)-isomer; all RRs refers to (D)-isomer unless otherwise noted

Molecular weight: 455.67
Formula: C12H22O14Zn
CLOGP:
LIPINSKI: None
HAC: None
HDO: None
TPSA: 141.28
ALOGS:
ROTB: None

Drug dosage:

None

ADMET properties:

None

Approvals:

Date	Agency	Company	Orphan
None	FDA

FDA Adverse Event Reporting System (Female)

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MedDRA adverse event term	Likelihood ratio	Likelihood ratio threshold	Patients taking drug having adverse event	Patients taking drug not having adverse event	Patients not taking drug having adverse event	Patients not taking drug not having adverse event
Sedation complication	512.32	13.41	191	22558	13631	63452642
Creatinine renal clearance decreased	485.11	13.41	192	22557	16116	63450157
Blood calcium decreased	420.15	13.41	200	22549	26251	63440022
Orthostatic hypotension	358.33	13.41	199	22550	35961	63430312
Sedation	342.53	13.41	198	22551	38611	63427662
Cognitive disorder	316.45	13.41	215	22534	55600	63410673
Depressed level of consciousness	264.40	13.41	201	22548	61877	63404396
Balance disorder	263.64	13.41	228	22521	84194	63382079
Mobility decreased	219.81	13.41	243	22506	120916	63345357
Constipation	192.08	13.41	312	22437	224631	63241642

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FDA Adverse Event Reporting System (Male)

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MedDRA adverse event term	Likelihood ratio	Likelihood ratio threshold	Patients taking drug having adverse event	Patients taking drug not having adverse event	Patients not taking drug having adverse event	Patients not taking drug not having adverse event
Off label use	77.12	14.79	245	8015	419279	34529392
Rhinocerebral mucormycosis	55.89	14.79	15	8245	553	34948118
COVID-19	54.98	14.79	79	8181	77471	34871200
Radiation inflammation	40.62	14.79	13	8247	892	34947779
Pulmonary pain	36.77	14.79	13	8247	1211	34947460
Anosmia	35.90	14.79	18	8242	4006	34944665
Product dose omission issue	31.62	14.79	80	8180	119631	34829040
Fatigue	26.18	14.79	163	8097	370490	34578181
Aplastic anaemia	21.38	14.79	18	8242	9698	34938973
Vascular device infection	18.95	14.79	12	8248	4173	34944498

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FDA Adverse Event Reporting System (Geriatric)

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MedDRA adverse event term	Likelihood ratio	Likelihood ratio threshold	Patients taking drug having adverse event	Patients taking drug not having adverse event	Patients not taking drug having adverse event	Patients not taking drug not having adverse event
Sedation complication	526.44	12.70	195	25074	15474	79703645
Creatinine renal clearance decreased	493.37	12.70	196	25073	18806	79700313
Blood calcium decreased	426.36	12.70	206	25063	31613	79687506
Sedation	324.32	12.70	203	25066	51692	79667427
Orthostatic hypotension	314.51	12.70	205	25064	55959	79663160
Cognitive disorder	305.63	12.70	219	25050	69707	79649412
Balance disorder	250.70	12.70	225	25044	98632	79620487
Mobility decreased	231.91	12.70	237	25032	121938	79597181
Depressed level of consciousness	210.26	12.70	202	25067	96450	79622669
Constipation	173.94	12.70	317	24952	282733	79436386

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FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

Source	Code	Description
ATC	A12CB02	ALIMENTARY TRACT AND METABOLISM MINERAL SUPPLEMENTS OTHER MINERAL SUPPLEMENTS Zinc

Drug Use | Suggest Off label Use Form| |View source of the data|

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Disease	Relation	SNOMED_ID	DOID
Ascorbic acid deficiency	indication	76169001
Zinc deficiency	indication	238124008
Hereditary acrodermatitis enteropathica	off-label use	37702000
Methemoglobinemia	off-label use	38959009	DOID:10783
Viral gastroenteritis	off-label use	111843007
Cerebral trauma	off-label use	275382005
Attention deficit hyperactivity disorder	off-label use	406506008
Primary hyperoxaluria	contraindication	17901006	DOID:2977
Hypocupremia	contraindication	19577007
Multiple sclerosis	contraindication	24700007	DOID:2377

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🐶 Veterinary Drug Use

Species	Use	Relation
Dogs	Chemical sterilization	Indication

🐶 Veterinary products

Product	Applicant	Ingredients
Zeuterin	Ark Sciences Inc.	1

Acid dissociation constants calculated using MoKa v3.0.0

None

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

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Search:

ID	Source
000843	NDDF
001943	NDDF
111039007	SNOMEDCT_US
12389-19-4	SECONDARY_CAS_RN
1440975	RXNORM
34828	MMSL
4020507	VANDF
4020809	VUID
4020809	VANDF
420444000	SNOMEDCT_US

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Pharmaceutical products:

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Product	Category	Ingredients	NDC	Form	Quantity	Route	Marketing	Label
Dermamed Nutrition for troubled skin	HUMAN OTC DRUG LABEL	7	69711-687	CAPSULE, GELATIN COATED	10 mg	ORAL	OTC monograph not final	10 sections
Detangjiang	HUMAN OTC DRUG LABEL	8	82570-018	POWDER	2 g	TOPICAL	unapproved drug other	8 sections
Detanjiang	HUMAN OTC DRUG LABEL	8	82570-008	POWDER	2 g	TOPICAL	unapproved drug other	8 sections
Floriva	HUMAN PRESCRIPTION DRUG LABEL	16	52796-173	TABLET, CHEWABLE	5 mg	ORAL	UNAPPROVED DRUG OTHER	6 sections
Floriva	HUMAN PRESCRIPTION DRUG LABEL	16	52796-174	TABLET, CHEWABLE	5 mg	ORAL	UNAPPROVED DRUG OTHER	6 sections
Floriva	HUMAN PRESCRIPTION DRUG LABEL	16	52796-177	TABLET, CHEWABLE	5 mg	ORAL	UNAPPROVED DRUG OTHER	7 sections
Gynetox	HUMAN OTC DRUG LABEL	21	57520-0103	LIQUID	6 [hp_X]	ORAL	unapproved homeopathic	9 sections
NBB	HUMAN OTC DRUG LABEL	3	64762-862	SPRAY, METERED	12.42 mg	ORAL	OTC MONOGRAPH FINAL	24 sections
NBE	HUMAN OTC DRUG LABEL	2	64762-871	SPRAY, METERED	12.26 mg	ORAL	OTC MONOGRAPH FINAL	12 sections
ZINC INJECTABLE A 1mg/ml, solution injectable pour perfusion	HUMAN PRESCRIPTION DRUG LABEL	1	60710-001	INJECTION, SOLUTION	1 mg	INTRAVENOUS	Unapproved drug for use in drug shortage	2 sections

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