crospovidone Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
4278 9003-39-8

Description:

MoleculeDescription

Synonyms:

  • povidone
  • polyvidon
  • polyvidone
  • crospovidone
A polyvinyl polymer of variable molecular weight; used as suspending and dispersing agent and vehicle for pharmaceuticals; also used as blood volume expander.
  • Molecular weight:
  • Formula: (C6H9NO)n
  • CLOGP:
  • LIPINSKI: None
  • HAC: None
  • HDO: None
  • TPSA:
  • ALOGS:
  • ROTB: None

Drug dosage:

None

ADMET properties:

None

Approvals:

DateAgencyCompanyOrphan
None FDA

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

Pharmacologic Action:

SourceCodeDescription
ATC A07BC03 ALIMENTARY TRACT AND METABOLISM
ANTIDIARRHEALS, INTESTINAL ANTIINFLAMMATORY/ANTIINFECTIVE AGENTS
INTESTINAL ADSORBENTS
Other intestinal adsorbents
MeSH PA D001802 Blood Substitutes
MeSH PA D006401 Hematologic Agents
MeSH PA D010592 Pharmaceutic Aids
MeSH PA D010952 Plasma Substitutes
CHEBI has role CHEBI:33295 diagnostic aid
CHEBI has role CHEBI:38849 blood substitutes
CHEBI has role CHEBI:50248 hematologic agents

Drug Use (View source of the data)

DiseaseRelationSNOMED_IDDOID
Tear film insufficiency indication 46152009
Red eye indication 75705005
Keratoconjunctivitis sicca off-label use 302896008 DOID:12895
Bacterial septicemia contraindication 10001005 DOID:0040085
Shock contraindication 27942005
Decreased respiratory function contraindication 80954004
Open wound contraindication 125643001
Seizure disorder contraindication 128613002
Heart block contraindication 233916004
Disease of liver contraindication 235856003 DOID:409
Pregnancy, function contraindication 289908002
Denuded skin contraindication 418242004

Acid dissociation constants calculated using MoKa v3.0.0

None

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

IDSource
4017478 VUID
N0000145866 NUI
D02295 KEGG_DRUG
4017478 VANDF
4020102 VANDF
C0728803 UMLSCUI
CHEBI:53248 CHEBI
CHEMBL2108848 ChEMBL_ID
CHEMBL2108139 ChEMBL_ID
4559 INN_ID
2S7830E561 UNII
131751496 PUBCHEM_CID
DB11061 DRUGBANK_ID
1310706 RXNORM
19304 MMSL
002537 NDDF
396449009 SNOMEDCT_US
56934003 SNOMEDCT_US
D011205 MESH_DESCRIPTOR_UI

Pharmaceutical products:

None