hydroxyproline Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
4272 51-35-4

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • hydroxyproline
  • 4-Hydroxy-L-proline
  • 4-Hydroxyproline
A hydroxylated form of the imino acid proline. A deficiency in ASCORBIC ACID can result in impaired hydroxyproline formation.
  • Molecular weight: 131.13
  • Formula: C5H9NO3
  • CLOGP: -1.91
  • LIPINSKI: 0
  • HAC: 4
  • HDO: 3
  • TPSA: 69.56
  • ALOGS: 0.57
  • ROTB: 1

Drug dosage:

None

ADMET properties:

None

Approvals:

DateAgencyCompanyOrphan
None FDA

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

Pharmacologic Action:

None

Drug Use (View source of the data)

None

Acid dissociation constants calculated using MoKa v3.0.0

Dissociation levelDissociation constantType (acidic/basic)
pKa1 2.11 acidic
pKa2 9.91 Basic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

IDSource
D006909 MESH_DESCRIPTOR_UI
N0000170257 NUI
C0020388 UMLSCUI
74727008 SNOMEDCT_US
1311548 RXNORM
RMB44WO89X UNII
HYP PDB_CHEM_ID
DB08847 DRUGBANK_ID
CHEBI:18095 CHEBI
5810 PUBCHEM_CID

Pharmaceutical products:

ProductCategoryIngredientsNDCFormQuantityRouteMarketingLabel
GONGJINHYANG MI LUXURY FOUNDATION 2 HUMAN OTC DRUG LABEL 2 53208-410 CREAM 0.53 mL TOPICAL OTC monograph not final 6 sections
OHUI Wrinkle Science wrinkle repair eye HUMAN OTC DRUG LABEL 1 53208-429 CREAM 0.51 1 TOPICAL unapproved drug other 6 sections
O HUI WRINKLE SCIENCE WRINKLE REPAIR HUMAN OTC DRUG LABEL 1 53208-430 CREAM 0.50 1 TOPICAL unapproved drug other 6 sections
ISA KNOX AGELESS SERUM MAKEUP BASE 10 HUMAN OTC DRUG LABEL 6 53208-471 CREAM 0.53 mL TOPICAL OTC monograph not final 5 sections
ISAKNOX AGELESS SERUM MOIST PEARL BASE HUMAN OTC DRUG LABEL 6 53208-478 LIQUID 0.53 mL TOPICAL OTC monograph not final 5 sections
OUHI CELL POWER NO 1 ESSENCE HUMAN OTC DRUG LABEL 2 53208-491 LIQUID 0.50 mL TOPICAL unapproved drug other 9 sections
OHUI THE FIRST CELL REVOLUTION AGE CONTROL SUN BLOCK HUMAN OTC DRUG LABEL 6 53208-515 CREAM 0.50 g TOPICAL OTC monograph not final 4 sections
ISA KNOX SMART BB SUN HUMAN OTC DRUG LABEL 4 53208-520 CREAM 0.50 mL TOPICAL OTC monograph not final 5 sections