hydroxyproline 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
4272 51-35-4

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • hydroxyproline
  • 4-Hydroxy-L-proline
  • 4-Hydroxyproline
A hydroxylated form of the imino acid proline. A deficiency in ASCORBIC ACID can result in impaired hydroxyproline formation.
  • Molecular weight: 131.13
  • Formula: C5H9NO3
  • CLOGP: -1.91
  • LIPINSKI: 0
  • HAC: 4
  • HDO: 3
  • TPSA: 69.56
  • ALOGS: 0.57
  • ROTB: 1

Drug dosage:

None

ADMET properties:

None

Approvals:

DateAgencyCompanyOrphan
None FDA

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

None

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

SourceCodeDescription
CHEBI has role CHEBI:75771 Mus musculus metabolites
CHEBI has role CHEBI:76924 plant metabolites
CHEBI has role CHEBI:77746 Homo sapiens metabolite

Drug Use | Suggest Off label Use Form| |View source of the data|

None




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

Dissociation levelDissociation constantType (acidic/basic)
pKa1 2.11 acidic
pKa2 9.91 Basic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

IDSource
N0000170257 NUI
C0020388 UMLSCUI
CHEBI:18095 CHEBI
HYP PDB_CHEM_ID
D006909 MESH_DESCRIPTOR_UI
DB08847 DRUGBANK_ID
RMB44WO89X UNII
5810 PUBCHEM_CID
1311548 RXNORM
74727008 SNOMEDCT_US

Pharmaceutical products:

ProductCategoryIngredientsNDCFormQuantityRouteMarketingLabel
GONGJINHYANG MI LUXURY FOUNDATION 2 HUMAN OTC DRUG LABEL 2 53208-410 CREAM 0.53 mL TOPICAL OTC monograph not final 12 sections
OHUI Wrinkle Science wrinkle repair eye HUMAN OTC DRUG LABEL 1 53208-429 CREAM 0.51 1 TOPICAL unapproved drug other 12 sections
O HUI WRINKLE SCIENCE WRINKLE REPAIR HUMAN OTC DRUG LABEL 1 53208-430 CREAM 0.50 1 TOPICAL unapproved drug other 12 sections
ISA KNOX AGELESS SERUM MAKEUP BASE 10 HUMAN OTC DRUG LABEL 6 53208-471 CREAM 0.53 mL TOPICAL OTC monograph not final 5 sections
ISAKNOX AGELESS SERUM MOIST PEARL BASE HUMAN OTC DRUG LABEL 6 53208-478 LIQUID 0.53 mL TOPICAL OTC monograph not final 5 sections
OUHI CELL POWER NO 1 ESSENCE HUMAN OTC DRUG LABEL 2 53208-491 LIQUID 0.50 mL TOPICAL unapproved drug other 9 sections
OHUI THE FIRST CELL REVOLUTION AGE CONTROL SUN BLOCK HUMAN OTC DRUG LABEL 6 53208-515 CREAM 0.50 g TOPICAL OTC monograph not final 5 sections
ISA KNOX SMART BB SUN HUMAN OTC DRUG LABEL 5 53208-520 CREAM 0.50 mL TOPICAL OTC monograph not final 6 sections