Padimate O 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | PK/Tox | Related Drugs | BioActivity |

Stem definitionDrug idCAS RN
4270 21245-02-3

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • Padimate O
  • Octyl dimethyl PABA
  • Molecular weight: 277.41
  • Formula: C17H27NO2
  • CLOGP: 6.16
  • LIPINSKI: 1
  • HAC: 3
  • HDO: 0
  • TPSA: 29.54
  • ALOGS: -3.89
  • ROTB: 9

Drug dosage:

None

ADMET properties:

None

Predicted pharmacokinetic/toxicological properties (PK-AZ):

PropertyDescriptionValueUnitConfidenceSimilarity
kinase-safety-class ACVR2A,ACVR2B,AKT2,AKT3,AURKA,AXL,BRAF,BTK,CAMK2B,CAMK2D,CDK5,CDK9,CHEK1,DDR1,DYRK1B,EIF2AK3,EPHB4,ERBB2,FLT3,GRK2,GSK3B,ITK,JAK1,JAK2,JAK3,MAP3K1,MAP3K21,MAP3K7,MAP4K1,MAP4K3,MAPK10,MAPK12,MAPK7,MAPK9,MAPKAPK2,MARK4,MET,MTOR,NTRK2,PDK2,PDK4,PDPK1,PIK3CB,PIM2,PRKCD,PRKDC,SIK2,SIK3,STK33,SYK,TEK,TTK,ULK1 53
kinase-selectivity-class AXL,BRAF,DDR1,EIF2AK3,GRK2,MAPK7,PDK4,SIK2,STK33,TEK,TTK 11
pfas-class PFAS structural alert (1 = True, 0 = False) 0

Approvals:

DateAgencyCompanyOrphan
None FDA

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

None

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

SourceCodeDescription
MeSH PA D003879 Dermatologic Agents
MeSH PA D011837 Radiation-Protective Agents
MeSH PA D013473 Sunscreening Agents
MeSH PA D020011 Protective Agents

Drug Use | Suggest Off label Use Form| |View source of the data|

None




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

Dissociation levelDissociation constantType (acidic/basic)
pKa1 2.47 Basic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

IDSource
4019468 VUID
N0000179207 NUI
D05335 KEGG_DRUG
4019283 VANDF
4019468 VANDF
4020732 VANDF
C0069937 UMLSCUI
CHEBI:135932 CHEBI
CHEMBL1323699 ChEMBL_ID
DB11570 DRUGBANK_ID
C041981 MESH_SUPPLEMENTAL_RECORD_UI
Z11006CMUZ UNII
30541 PUBCHEM_CID
32786 RXNORM
001971 NDDF
005913 NDDF

Pharmaceutical products:

ProductCategoryIngredientsNDCFormQuantityRouteMarketingLabel
Lip Balm Sunscreen SPF 4Original HUMAN OTC DRUG LABEL 1 0363-6050 STICK 1.50 mg TOPICAL OTC monograph final 11 sections
Lip Balm Sunscreen SPF 4Cherry Flavor HUMAN OTC DRUG LABEL 1 0363-6060 STICK 1.50 mg TOPICAL OTC monograph final 11 sections
Blistex Medicated Mint Lip Balm HUMAN OTC DRUG LABEL 3 10157-9608 STICK 6.60 g TOPICAL OTC MONOGRAPH FINAL 13 sections
Blistex Medicated Berry Balm HUMAN OTC DRUG LABEL 3 10157-9713 STICK 6.60 g TOPICAL OTC monograph final 13 sections
Blistex Medicated Lip Balm HUMAN OTC DRUG LABEL 3 10157-9822 STICK 6.60 g TOPICAL OTC MONOGRAPH FINAL 13 sections
EA EIGHT HR LIP SHEER TINTS HUMAN OTC DRUG LABEL 3 10967-674 LIPSTICK 8 mg TOPICAL OTC Monograph Drug 9 sections
Rayito de Sol Sunscreen SPF 18 HUMAN OTC DRUG LABEL 3 20367-113 CREAM 4.20 g TOPICAL OTC monograph final 13 sections
KROGER SPF 4 TANNING OIL HUMAN OTC DRUG LABEL 2 30142-929 SPRAY 1.40 g TOPICAL OTC monograph not final 12 sections
Shopko Cherry SPF 4 Lip Balm HUMAN OTC DRUG LABEL 2 37012-731 STICK 1.50 mg TOPICAL OTC monograph not final 8 sections
Shopko Original SPF 4 Lip Balm HUMAN OTC DRUG LABEL 2 37012-732 STICK 1.50 mg TOPICAL OTC monograph not final 8 sections
Pro-Tect Everyday Sunscreen SPF 15 HUMAN OTC DRUG LABEL 3 37945-868 LOTION 50 mg TOPICAL OTC monograph not final 9 sections
MEIJER SPF 4 TANNING OIL HUMAN OTC DRUG LABEL 2 41250-039 LOTION 1.40 g TOPICAL OTC monograph not final 11 sections
Care One Cherry SPF 4 Lip Balm HUMAN OTC DRUG LABEL 2 41520-978 STICK 1.50 mg TOPICAL OTC monograph final 8 sections
Care One Original SPF 4 Lip Balm HUMAN OTC DRUG LABEL 2 41520-979 STICK 1.50 mg TOPICAL OTC monograph final 8 sections
Ariel Sun Smacker SPF 24 Strawberry Kiwi HUMAN OTC DRUG LABEL 3 50051-0001 LIPSTICK 8 g TOPICAL OTC monograph not final 14 sections
Flounder Sun Smacker SPF 24 Watermelon Wave HUMAN OTC DRUG LABEL 3 50051-0002 LIPSTICK 8 g TOPICAL OTC monograph not final 14 sections
Sebastian Sun Smacker SPF 24 Calypso Berry Beat HUMAN OTC DRUG LABEL 3 50051-0003 LIPSTICK 8 g TOPICAL OTC monograph not final 14 sections
Donald Duck Sun Smacker SPF 24 Tropical Touchdown HUMAN OTC DRUG LABEL 3 50051-0004 LIPSTICK 8 g TOPICAL OTC monograph not final 14 sections
Goofy Sun Smacker SPF 24 Berry Goal HUMAN OTC DRUG LABEL 3 50051-0005 LIPSTICK 8 g TOPICAL OTC monograph not final 14 sections
Mickey Sun Smacker SPF 24 Classic Sherbet HUMAN OTC DRUG LABEL 3 50051-0006 LIPSTICK 8 g TOPICAL OTC monograph not final 14 sections
Mickey Sun Smacker SPF 24 Classic Strawberry HUMAN OTC DRUG LABEL 3 50051-0007 LIPSTICK 8 g TOPICAL OTC monograph not final 14 sections
Mickey Sun Smacker SPF 24 Classic Vanilla HUMAN OTC DRUG LABEL 3 50051-0008 LIPSTICK 8 g TOPICAL OTC monograph not final 14 sections
Mickey Sun Smacker SPF 24 Home Run Star Fruit HUMAN OTC DRUG LABEL 3 50051-0009 LIPSTICK 8 g TOPICAL OTC monograph not final 14 sections
Lightning McQueen Sun Smacker SPF 24 Revved Up Raspberry HUMAN OTC DRUG LABEL 3 50051-0010 LIPSTICK 8 g TOPICAL OTC monograph not final 14 sections
Tow Mater Sun Smacker SPF 24 Tow-Tally Orange HUMAN OTC DRUG LABEL 3 50051-0011 LIPSTICK 8 g TOPICAL OTC monograph not final 14 sections
Fin McMissie Sun Smacker SPF 24 Vroom Vroom Vanilla HUMAN OTC DRUG LABEL 3 50051-0012 LIPSTICK 8 g TOPICAL OTC monograph not final 14 sections
Phineas and Ferb Sun Smacker SPF 24 Berry Busted HUMAN OTC DRUG LABEL 3 50051-0013 LIPSTICK 8 g TOPICAL OTC monograph not final 14 sections
Phineas and Ferb Sun Smacker SPF 24 Secret Agent Strawberry HUMAN OTC DRUG LABEL 3 50051-0014 LIPSTICK 8 g TOPICAL OTC monograph not final 14 sections
Phineas and Ferb Sun Smacker SPF 24 Vanilla Vacation HUMAN OTC DRUG LABEL 3 50051-0015 LIPSTICK 8 g TOPICAL OTC monograph not final 14 sections
Lip Smacker SPF 24 Cool Strawberry Orange HUMAN OTC DRUG LABEL 3 50051-0016 LIPSTICK 8 g TOPICAL OTC monograph not final 7 sections