zinc acetate 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | PK/Tox | Related Drugs | BioActivity |

Stem definitionDrug idCAS RN
4269 557-34-6

Description:

MoleculeDescription

Synonyms:

  • zinc acetate anhydrous
  • zinc acetate dihydrate
  • wilzin
  • zinc acetate
  • zinc diacetate
  • zinc acetate hydrate
  • nobelzin
A salt produced by the reaction of zinc oxide with acetic acid and used as an astringent, styptic, and emetic.
  • Molecular weight: 183.47
  • Formula: C4H6O4Zn
  • CLOGP: -2.49
  • LIPINSKI: None
  • HAC: None
  • HDO: None
  • TPSA: 40.13
  • ALOGS:
  • ROTB: None

Drug dosage:

DoseUnitRoute
0.15 g O

ADMET properties:

None

Predicted pharmacokinetic/toxicological properties (PK-AZ):

None

Approvals:

DateAgencyCompanyOrphan
Jan. 22, 2021 PMDA NOBELPHARMA Co., Ltd
Feb. 22, 1980 FDA ARMOUR PHARM

FDA Adverse Event Reporting System (Female)

MedDRA adverse event termLikelihood ratioLikelihood ratio thresholdPatients taking drug having adverse eventPatients taking drug not having adverse eventPatients not taking drug having adverse eventPatients not taking drug not having adverse event
Anosmia 94.89 24.16 23 1254 9825 90617345
Ageusia 44.04 24.16 14 1263 16062 90611108
Corneal neovascularisation 26.16 24.16 4 1273 147 90627023
Hyposmia 24.54 24.16 5 1272 964 90626206

FDA Adverse Event Reporting System (Male)

MedDRA adverse event termLikelihood ratioLikelihood ratio thresholdPatients taking drug having adverse eventPatients taking drug not having adverse eventPatients not taking drug having adverse eventPatients not taking drug not having adverse event
Anosmia 51.31 31.33 12 502 5164 42615657

FDA Adverse Event Reporting System (Geriatric)

MedDRA adverse event termLikelihood ratioLikelihood ratio thresholdPatients taking drug having adverse eventPatients taking drug not having adverse eventPatients not taking drug having adverse eventPatients not taking drug not having adverse event
Anosmia 124.19 25.10 30 1553 12442 110575274
Ageusia 45.00 25.10 15 1568 19630 110568086

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

SourceCodeDescription
ATC A16AX05 ALIMENTARY TRACT AND METABOLISM
OTHER ALIMENTARY TRACT AND METABOLISM PRODUCTS
OTHER ALIMENTARY TRACT AND METABOLISM PRODUCTS
Various alimentary tract and metabolism products
CHEBI has role CHEBI:22587 antiviral agent
CHEBI has role CHEBI:33281 antimicrobial agent
CHEBI has role CHEBI:51177 antitussive
CHEBI has role CHEBI:67079 anti-inflammatory agent
CHEBI has role CHEBI:74783 astringent

Related Drugs by ATC class:

A16AX Various alimentary tract and metabolism products 23 drugs
anethole trithionedoxecitinedoxribtimineeliglustatfosdenopteringivosiranglycerol phenylbutyratelonafarniblumasiranmigalastatmiglustatnedosiran show all 23 →

Drug Use | Suggest Off label Use Form| |View source of the data|

DiseaseRelationSNOMED_IDDOID
Otitis externa indication 3135009
Proctitis indication 3951002 DOID:3127
Wound indication 13924000
Burn injury indication 48333001
Hemorrhoids indication 70153002 DOID:9746
Rectal pain indication 77880009
Wilson's disease indication 88518009
Diaper rash indication 91487003
Hypozincemia indication 238124008
Eruption of skin indication 271807003 DOID:0050486
Skin irritation indication 367466007
Arthropod bite wound indication 409985002
Itching of skin indication 418363000
Itching of ear indication 699392007
Otalgia off-label use 16001004
Impacted cerumen off-label use 18070006
Hypocupremia contraindication 19577007
Perforation of tympanic membrane contraindication 60442001
Open wound contraindication 125643001
Infective otitis media contraindication 312218008
Denuded skin contraindication 418242004
Porphyria contraindication 418470004




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

None

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

IDSource
4021033 VUID
N0000148498 NUI
5970-45-6 SECONDARY_CAS_RN
4021033 VANDF
C0149368 UMLSCUI
CHEMBL3184986 ChEMBL_ID
CHEMBL1200928 ChEMBL_ID
D019345 MESH_DESCRIPTOR_UI
DB14487 DRUGBANK_ID
FM5526K07A UNII
11192 PUBCHEM_CID
1299637 RXNORM
27914 MMSL
5706 MMSL
72545 MMSL
NOCODE MMSL
d04123 MMSL
003862 NDDF
003863 NDDF
015397 NDDF
395952003 SNOMEDCT_US
412376004 SNOMEDCT_US
CHEBI:62984 CHEBI
FM5526K07A INXIGHT DRUGS

Pharmaceutical products:

ProductCategoryIngredientsNDCFormQuantityRouteMarketingLabel
good sense itch relief HUMAN OTC DRUG LABEL 2 0113-0622 CREAM 0.10 g TOPICAL OTC Monograph Drug 14 sections
Caladryl Clear HUMAN OTC DRUG LABEL 2 0187-5466 LOTION 1 mg TOPICAL OTC Monograph Drug 14 sections
WAL- DRYL ITCH RELIEF HUMAN OTC DRUG LABEL 2 0363-0121 CREAM 1 mg TOPICAL OTC MONOGRAPH NOT FINAL 15 sections
Wal-dryl HUMAN OTC DRUG LABEL 2 0363-0122 CREAM 0.10 mg TOPICAL OTC MONOGRAPH NOT FINAL 13 sections
Diphenhydramine HCl and Zinc Acetate HUMAN OTC DRUG LABEL 2 0363-0215 SPRAY 0.08 g TOPICAL OTC Monograph Drug 15 sections
Diphenhydramine HCl and Zinc Acetate HUMAN OTC DRUG LABEL 2 0363-0215 SPRAY 0.08 g TOPICAL OTC Monograph Drug 15 sections
WALGREENS ANTI ITCH HUMAN OTC DRUG LABEL 2 0363-1411 CREAM 0.10 g TOPICAL OTC monograph final 13 sections
EXTRA STRENGTH WAL-DRYL ITCH RELIEF HUMAN OTC DRUG LABEL 2 0363-2177 SPRAY 1 mg TOPICAL OTC Monograph Drug 15 sections
Walgreens Anti Itch Cream HUMAN OTC DRUG LABEL 2 0363-2315 CREAM 1 mg TOPICAL OTC Monograph Drug 10 sections
Walgreens Original Strength Anti Itch HUMAN OTC DRUG LABEL 2 0363-4115 CREAM 0.10 g TOPICAL OTC MONOGRAPH DRUG 15 sections
calahist clear HUMAN OTC DRUG LABEL 2 0363-9412 LOTION 1 mg TOPICAL OTC Monograph Drug 13 sections
Humco Calaclear HUMAN OTC DRUG LABEL 2 0395-0400 LOTION 1 mg TOPICAL OTC Monograph Drug 12 sections
Calaclear HUMAN OTC DRUG LABEL 2 0395-9108 LOTION 1 mg TOPICAL OTC monograph final 12 sections
Rugby Caldyphen Clear HUMAN OTC DRUG LABEL 2 0536-1269 LOTION 1 mg TOPICAL OTC Monograph Drug 8 sections
Banophen HUMAN OTC DRUG LABEL 2 0904-5354 CREAM 0.10 g TOPICAL OTC Monograph Drug 14 sections
Blistex Ivarest Poison Ivy Itch HUMAN OTC DRUG LABEL 2 10157-2100 SPRAY 0.12 g TOPICAL OTC monograph drug 12 sections
Clear Anti-Itch HUMAN OTC DRUG LABEL 2 11344-812 LOTION 1 mg TOPICAL OTC Monograph Drug 13 sections
Weeks and Leo Extra Strength Itch Stopping HUMAN OTC DRUG LABEL 2 11383-258 CREAM 1 mg TOPICAL OTC monograph not final 13 sections
Dr. Sheffield Anti Itch Cream HUMAN OTC DRUG LABEL 2 11527-069 CREAM 1 mg TOPICAL OTC Monograph Drug 9 sections
Anti-itch HUMAN OTC DRUG LABEL 2 11673-895 CREAM 1 mg TOPICAL OTC Monograph Drug 10 sections
Clear Anti-Itch HUMAN OTC DRUG LABEL 2 11822-0219 LOTION 1 mg TOPICAL OTC Monograph Drug 13 sections
Rite AidMaximum Strength Itch Relief HUMAN OTC DRUG LABEL 2 11822-0371 SPRAY 1 mg TOPICAL OTC monograph final 7 sections
Rite Aid Itch Relief HUMAN OTC DRUG LABEL 2 11822-0647 SPRAY 0.10 g TOPICAL OTC Monograph Drug 8 sections
Maximum Strength First Aid Anti-ItchRite Aid HUMAN OTC DRUG LABEL 2 11822-1228 SPRAY 0.10 g TOPICAL OTC monograph not final 11 sections
Rite Aid Cala Itch Relief HUMAN OTC DRUG LABEL 2 11822-3101 SPRAY 0.10 g TOPICAL OTC Monograph Drug 7 sections
Rite Aid Extra Strength Itch Stopping HUMAN OTC DRUG LABEL 2 11822-6614 CREAM 1 mg TOPICAL OTC Monograph Drug 13 sections
First Aid Clear Anti-Itch medicated padsRite Aid HUMAN OTC DRUG LABEL 2 11822-7781 LIQUID 0.10 g TOPICAL OTC monograph final 9 sections
Extra Strength First Aid Anti-itchRite Aid HUMAN OTC DRUG LABEL 2 11822-7796 SPRAY 0.10 g TOPICAL OTC monograph not final 12 sections
Select Brand Itch Relief HUMAN OTC DRUG LABEL 2 15127-054 SPRAY 0.01 g TOPICAL OTC monograph final 14 sections
signature care itch relief HUMAN OTC DRUG LABEL 2 21130-154 CREAM 0.10 g TOPICAL OTC Monograph Drug 14 sections