potassium nitrate 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | PK/Tox | Related Drugs | BioActivity |

Stem definitionDrug idCAS RN
NO2 - derivatives 4263 7757-79-1

Description:

MoleculeDescription

Synonyms:

  • potassium nitrate
  • nitric acid potassium salt
  • saltpeter
  • Molecular weight: 101.10
  • Formula: KNO3
  • CLOGP:
  • LIPINSKI: None
  • HAC: None
  • HDO: None
  • TPSA:
  • ALOGS:
  • ROTB: None

Drug dosage:

None

ADMET properties:

None

Predicted pharmacokinetic/toxicological properties (PK-AZ):

None

Approvals:

DateAgencyCompanyOrphan
None FDA

FDA Adverse Event Reporting System (Female)

MedDRA adverse event termLikelihood ratioLikelihood ratio thresholdPatients taking drug having adverse eventPatients taking drug not having adverse eventPatients not taking drug having adverse eventPatients not taking drug not having adverse event
Walking aid user 101.63 14.97 60 11105 35446 90581836
Prescribed underdose 87.29 14.97 73 11092 74946 90542336
Seronegative arthritis 74.62 14.97 39 11126 18195 90599087
Wound infection 69.10 14.97 75 11090 106327 90510955
Spinal fusion surgery 67.20 14.97 32 11133 12251 90605031
Upper respiratory tract infection 64.09 14.97 79 11086 128239 90489043
Visual impairment 60.56 14.97 78 11087 132287 90484995
Spondylitis 51.46 14.97 28 11137 14150 90603132
Joint dislocation 46.97 14.97 41 11124 44541 90572741
Lupus vulgaris 42.64 14.97 39 11126 45020 90572262
Osteoporosis 41.21 14.97 55 11110 96476 90520806
Retinitis 39.77 14.97 35 11130 38423 90578859
Hepatic cirrhosis 36.59 14.97 42 11123 63211 90554071
Foot deformity 35.17 14.97 40 11125 59611 90557671
Laryngitis 35.08 14.97 37 11128 50716 90566566
Anti-cyclic citrullinated peptide antibody 34.80 14.97 28 11137 27193 90590089
Type 2 diabetes mellitus 33.54 14.97 76 11089 203168 90414114
Adjustment disorder with depressed mood 33.36 14.97 38 11127 56715 90560567
Lupus-like syndrome 32.68 14.97 35 11130 48811 90568471
Joint stiffness 32.59 14.97 44 11121 77998 90539284
Dislocation of vertebra 30.43 14.97 36 11129 55932 90561350
Drug ineffective 28.12 14.97 83 11082 1384215 89233067
Exostosis 26.96 14.97 33 11132 53101 90564181
Wheezing 26.75 14.97 77 11088 238003 90379279
Ear infection 25.64 14.97 37 11128 69738 90547544
Disability 25.17 14.97 28 11137 40717 90576565
Prescribed overdose 25.14 14.97 44 11121 97581 90519701
Weight decreased 24.40 14.97 102 11063 379808 90237474
Liver function test increased 24.17 14.97 40 11125 84815 90532467
Bone erosion 23.84 14.97 31 11134 52990 90564292
Deep vein thrombosis postoperative 23.79 14.97 36 11129 70773 90546509
Vertebral lateral recess stenosis 23.62 14.97 6 11159 346 90616936
Osteoarthropathy 23.36 14.97 6 11159 362 90616920
Ligamentum flavum hypertrophy 23.22 14.97 6 11159 371 90616911
Wound 23.21 14.97 86 11079 302894 90314388
Hip arthroplasty 23.17 14.97 37 11128 76171 90541111
Grip strength decreased 22.91 14.97 41 11124 92535 90524747
Red blood cell sedimentation rate increased 22.28 14.97 38 11127 82557 90534725
Oedema peripheral 22.14 14.97 76 11089 257839 90359443
Amnesia 21.83 14.97 44 11121 108461 90508821
Lower limb fracture 21.48 14.97 38 11127 84975 90532307
Weight increased 21.44 14.97 105 11060 417822 90199460
Urticaria 20.88 14.97 85 11080 312649 90304633
Stoma site discharge 20.13 14.97 8 11157 1981 90615301
Drug interaction 19.50 14.97 5 11160 276448 90340834
Sciatica 19.08 14.97 40 11125 101342 90515940
Autoimmune disorder 19.00 14.97 34 11131 76710 90540572
Stoma site erythema 18.65 14.97 7 11158 1489 90615793
Delirium 18.29 14.97 40 11125 104319 90512963
Oedema 18.04 14.97 60 11105 200235 90417047
Osteoarthritis 17.96 14.97 59 11106 195671 90421611
Psoriasis 17.77 14.97 49 11116 147705 90469577
Fibroma 17.58 14.97 6 11159 970 90616312
Pulmonary fibrosis 17.49 14.97 40 11125 107463 90509819
Road traffic accident 17.46 14.97 40 11125 107586 90509696
Hypoaesthesia eye 17.42 14.97 5 11160 459 90616823
Gait inability 17.05 14.97 48 11117 146408 90470874
Hypercholesterolaemia 16.93 14.97 38 11127 100854 90516428
Memory impairment 16.81 14.97 58 11107 197186 90420096
Toe operation 16.53 14.97 6 11159 1162 90616120
Gait disturbance 15.97 14.97 69 11096 260427 90356855
Acute kidney injury 15.78 14.97 10 11155 320377 90296905
Stoma site haemorrhage 15.73 14.97 6 11159 1332 90615950
Breast cancer stage III 15.52 14.97 33 11132 84414 90532868
Fibromyalgia 15.32 14.97 58 11107 206211 90411071
On and off phenomenon 15.06 14.97 7 11158 2536 90614746

FDA Adverse Event Reporting System (Male)

MedDRA adverse event termLikelihood ratioLikelihood ratio thresholdPatients taking drug having adverse eventPatients taking drug not having adverse eventPatients not taking drug having adverse eventPatients not taking drug not having adverse event
Respiratory tract infection bacterial 92.02 19.89 22 2761 1887 42616665
Respiratory tract infection viral 84.01 19.89 23 2760 3383 42615169
Fibrin D dimer increased 50.62 19.89 17 2766 4968 42613584
Respiratory tract infection 43.75 19.89 25 2758 26297 42592255
Cytokine release syndrome 33.97 19.89 26 2757 44501 42574051
Testicular haemorrhage 23.51 19.89 5 2778 252 42618300
Stoma site erythema 21.14 19.89 6 2777 1004 42617548

FDA Adverse Event Reporting System (Geriatric)

MedDRA adverse event termLikelihood ratioLikelihood ratio thresholdPatients taking drug having adverse eventPatients taking drug not having adverse eventPatients not taking drug having adverse eventPatients not taking drug not having adverse event
Respiratory tract infection bacterial 82.64 14.61 22 8722 2394 110578161
Respiratory tract infection viral 67.23 14.61 23 8721 5855 110574700
Fibrin D dimer increased 36.22 14.61 17 8727 9828 110570727
Cytokine release syndrome 29.61 14.61 32 8712 70274 110510281
Respiratory tract infection 27.40 14.61 31 8713 71586 110508969
Vertebral lateral recess stenosis 26.27 14.61 6 8738 346 110580209
Ligamentum flavum hypertrophy 25.89 14.61 6 8738 369 110580186
Osteoarthropathy 25.83 14.61 6 8738 373 110580182
Therapeutic reaction time decreased 25.41 14.61 11 8733 5268 110575287
Testicular haemorrhage 22.63 14.61 5 8739 248 110580307
Seronegative arthritis 20.86 14.61 13 8731 13164 110567391
Toe operation 19.97 14.61 6 8738 1008 110579547
Spinal fusion surgery 19.66 14.61 11 8733 9145 110571410
Product dose omission issue 18.74 14.61 62 8682 321720 110258835
Drug interaction 17.28 14.61 9 8735 500174 110080381
Penile haemorrhage 16.29 14.61 5 8739 903 110579652
Stoma site erythema 15.65 14.61 6 8738 2111 110578444
Groin infection 15.48 14.61 5 8739 1065 110579490
Hypoaesthesia eye 15.34 14.61 4 8740 401 110580154

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

SourceCodeDescription
MeSH PA D053834 Explosive Agents
CHEBI has role CHEBI:33287 fertilizer
CHEBI has role CHEBI:35554 cardiovascular drug

Drug Use | Suggest Off label Use Form| |View source of the data|

DiseaseRelationSNOMED_IDDOID
Prevention of dental caries indication 426482000
Gingivitis off-label use 66383009 DOID:3087
Dental Plaque Prevention off-label use
Dental fluorosis contraindication 30265004




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

None

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

IDSource
4017466 VUID
N0000145854 NUI
D02051 KEGG_DRUG
4017466 VANDF
C0071772 UMLSCUI
CHEBI:63043 CHEBI
CHEMBL1644029 ChEMBL_ID
DB11090 DRUGBANK_ID
C023844 MESH_SUPPLEMENTAL_RECORD_UI
RU45X2JN0Z UNII
24434 PUBCHEM_CID
34316 RXNORM
5334 MMSL
NOCODE MMSL
000692 NDDF
419267005 SNOMEDCT_US
77431009 SNOMEDCT_US

Pharmaceutical products:

ProductCategoryIngredientsNDCFormQuantityRouteMarketingLabel
PreviDent 5000 Enamel Protect HUMAN PRESCRIPTION DRUG LABEL 2 0126-0022 GEL, DENTIFRICE 57.50 mg DENTAL UNAPPROVED DRUG OTHER 21 sections
PreviDent 5000 Sensitive HUMAN PRESCRIPTION DRUG LABEL 2 0126-0070 GEL, DENTIFRICE 57.50 mg DENTAL UNAPPROVED DRUG OTHER 21 sections
SENSODYNE PRONAMELmineral BOOST refreshing peppermint HUMAN OTC DRUG LABEL 2 0135-0450 PASTE 50 mg ORAL OTC Monograph Drug 11 sections
SENSODYNE PRONAMEL Daily Protection HUMAN OTC DRUG LABEL 2 0135-0460 PASTE 50 mg ORAL OTC Monograph Drug 11 sections
SENSODYNE Advanced Whitening HUMAN OTC DRUG LABEL 2 0135-0479 PASTE 50 mg ORAL OTC Monograph Drug 11 sections
SENSODYNE PRONAMELmineral BOOST whitening action HUMAN OTC DRUG LABEL 2 0135-0480 PASTE 50 mg ORAL OTC Monograph Drug 11 sections
SENSODYNE PRONAMEL Intensive Enamel Repair Whitening HUMAN OTC DRUG LABEL 2 0135-0481 PASTE 50 mg ORAL OTC Monograph Drug 12 sections
SENSODYNE PRONAMEL Gentle Whitening HUMAN OTC DRUG LABEL 2 0135-0484 PASTE 50 mg ORAL OTC Monograph Drug 11 sections
SENSODYNE PRONAMEL Intensive Enamel Repair Extra Fresh HUMAN OTC DRUG LABEL 2 0135-0486 PASTE 50 mg ORAL OTC Monograph Drug 12 sections
SENSODYNE PRONAMEL Intensive Enamel Repair Clean Mint HUMAN OTC DRUG LABEL 2 0135-0492 PASTE 50 mg ORAL OTC Monograph Drug 12 sections
SENSODYNE PRONAMEL Fresh Breath HUMAN OTC DRUG LABEL 2 0135-0520 PASTE 50 mg ORAL OTC Monograph Drug 11 sections
SensodyneExtra Whitening HUMAN OTC DRUG LABEL 2 0135-0525 PASTE 50 mg DENTAL OTC Monograph Drug 12 sections
Sensodyne Fresh Impact HUMAN OTC DRUG LABEL 2 0135-0528 PASTE 50 mg DENTAL OTC Monograph Drug 12 sections
Sensodyne Fresh Mint HUMAN OTC DRUG LABEL 2 0135-0529 PASTE 50 mg DENTAL OTC Monograph Drug 12 sections
Sensodyne HUMAN OTC DRUG LABEL 2 0135-0550 PASTE 50 mg DENTAL OTC Monograph Drug 12 sections
Sensodyne HUMAN OTC DRUG LABEL 2 0135-0551 PASTE 50 mg DENTAL OTC Monograph Drug 12 sections
SENSODYNE PRONAMEL Multi Action HUMAN OTC DRUG LABEL 2 0135-0568 PASTE 50 mg ORAL OTC Monograph Drug 11 sections
Sensodyne True white HUMAN OTC DRUG LABEL 2 0135-0579 PASTE 50 mg DENTAL OTC Monograph Drug 12 sections
Sensodyne PronamelGentle Whitening Advanced HUMAN OTC DRUG LABEL 2 0135-0580 PASTE 50 mg DENTAL OTC Monograph Drug 12 sections
Sensodyne True white HUMAN OTC DRUG LABEL 2 0135-0581 PASTE 50 mg DENTAL OTC Monograph Drug 12 sections
sensodyne HUMAN OTC DRUG LABEL 2 0135-0593 PASTE 50 mg DENTAL OTC Monograph Drug 12 sections
Sensodyne PronamelStrong and Bright Enamel Mint HUMAN OTC DRUG LABEL 2 0135-0602 PASTE 50 mg ORAL OTC Monograph Drug 12 sections
Sensodyne Pronamel Strong and Bright Enamel Extra Fresh HUMAN OTC DRUG LABEL 2 0135-0603 PASTE 50 mg ORAL OTC Monograph Drug 12 sections
AQUAFRESHSENSITIVE MAXIMUM STRENGTH HUMAN OTC DRUG LABEL 2 0135-0605 PASTE 50 mg DENTAL OTC Monograph Drug 12 sections
Sensodyne Extra Whitening Cool Mint HUMAN OTC DRUG LABEL 2 0135-0643 PASTE 50 mg DENTAL OTC Monograph Drug 12 sections
Sensodyne PronamelGentle Whitening Fresh Mint HUMAN OTC DRUG LABEL 2 0135-0644 PASTE 50 mg DENTAL OTC Monograph Drug 12 sections
SENSODYNE PRONAMEL Active Shield Fresh Mint HUMAN OTC DRUG LABEL 2 0135-0700 PASTE 50 mg ORAL OTC Monograph Drug 12 sections
SENSODYNE PRONAMEL Active Shield Cool Mint HUMAN OTC DRUG LABEL 2 0135-0701 PASTE 50 mg ORAL OTC Monograph Drug 12 sections
Sensodyne Clinical White Stain Protector HUMAN OTC DRUG LABEL 2 0135-0702 PASTE 50 mg ORAL OTC Monograph Drug 11 sections
Sensodyne Clinical White Enamel Strengthening HUMAN OTC DRUG LABEL 2 0135-0703 PASTE 50 mg ORAL OTC Monograph Drug 11 sections