thymol 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
4258 89-83-8

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • thymol
  • thyme camphor
  • thymol chrystals
A phenol obtained from thyme oil or other volatile oils used as a stabilizer in pharmaceutical preparations, and as an antiseptic (antibacterial or antifungal) agent.
  • Molecular weight: 150.22
  • Formula: C10H14O
  • CLOGP: 3.20
  • LIPINSKI: 0
  • HAC: 1
  • HDO: 1
  • TPSA: 20.23
  • ALOGS: -2.37
  • ROTB: 1

Drug dosage:

None

ADMET properties:

None

Approvals:

DateAgencyCompanyOrphan
None FDA

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

None

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

SourceCodeDescription
MeSH PA D000890 Anti-Infective Agents
MeSH PA D000891 Anti-Infective Agents, Local
MeSH PA D000935 Antifungal Agents
CHEBI has role CHEBI:27311 essential oil component

Drug Use | Suggest Off label Use Form| |View source of the data|

None




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

Dissociation levelDissociation constantType (acidic/basic)
pKa1 10.57 acidic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

TargetClassPharosUniProtActionTypeActivity value
(-log[M])
Mechanism
action
Bioact sourceMoA source
Transient receptor potential cation channel subfamily A member 1 Ion channel EC50 5.22 CHEMBL
Transient receptor potential cation channel subfamily M member 8 Ion channel EC50 4.28 CHEMBL
Heat sensitive channel TRPV3 Unclassified EC50 4.54 CHEMBL

External reference:

IDSource
4019136 VUID
N0000147386 NUI
D01039 KEGG_DRUG
4019136 VANDF
C0040096 UMLSCUI
CHEBI:27607 CHEBI
IPB PDB_CHEM_ID
CHEMBL29411 ChEMBL_ID
D013943 MESH_DESCRIPTOR_UI
DB02513 DRUGBANK_ID
2499 IUPHAR_LIGAND_ID
3J50XA376E UNII
6989 PUBCHEM_CID
10553 RXNORM
NOCODE MMSL
002914 NDDF
331322007 SNOMEDCT_US
54932001 SNOMEDCT_US

Pharmaceutical products:

ProductCategoryIngredientsNDCFormQuantityRouteMarketingLabel
Antiseptic Mouth Rinse HUMAN OTC DRUG LABEL 4 0363-0072 MOUTHWASH 0.06 kg ORAL OTC monograph not final 12 sections
Rinse HUMAN OTC DRUG LABEL 4 0363-0318 MOUTHWASH 0.64 mg ORAL OTC monograph not final 13 sections
Rinse HUMAN OTC DRUG LABEL 4 0363-0318 MOUTHWASH 0.64 mg ORAL OTC monograph not final 13 sections
Antispetic HUMAN OTC DRUG LABEL 4 0363-0664 MOUTHWASH 0.64 mg ORAL OTC monograph not final 14 sections
Antispetic HUMAN OTC DRUG LABEL 4 0363-0664 MOUTHWASH 0.64 mg ORAL OTC monograph not final 14 sections
Tartar control plus HUMAN OTC DRUG LABEL 4 0363-0855 MOUTHWASH 0.64 mg ORAL OTC monograph not final 13 sections
Antiseptic HUMAN OTC DRUG LABEL 4 0869-0072 MOUTHWASH 0.64 mg ORAL OTC monograph not final 12 sections
Antiseptic Mouth Rinse HUMAN OTC DRUG LABEL 4 0869-0318 MOUTHWASH 0.64 mg ORAL OTC monograph not final 13 sections
Antiseptic Mouth Rinse HUMAN OTC DRUG LABEL 4 0869-0318 MOUTHWASH 0.64 mg ORAL OTC monograph not final 13 sections
Tartar Control Plus HUMAN OTC DRUG LABEL 4 0869-0434 MOUTHWASH 0.64 mg ORAL OTC monograph not final 12 sections
Tartar Control Plus HUMAN OTC DRUG LABEL 4 0869-0434 MOUTHWASH 0.64 mg ORAL OTC monograph not final 12 sections
Antispetic HUMAN OTC DRUG LABEL 4 0869-0664 MOUTHWASH 0.64 mg ORAL OTC monograph not final 12 sections
Antispetic HUMAN OTC DRUG LABEL 4 0869-0664 MOUTHWASH 0.64 mg ORAL OTC monograph not final 12 sections
Antispetic HUMAN OTC DRUG LABEL 4 10202-664 MOUTHWASH 0.64 mg ORAL OTC monograph not final 11 sections
Antiseptic Mouth Rinse HUMAN OTC DRUG LABEL 4 11344-072 MOUTHWASH 0.06 kg ORAL OTC monograph not final 12 sections
Antiseptic Mouth Rinse HUMAN OTC DRUG LABEL 4 11344-318 MOUTHWASH 0.06 kg ORAL OTC monograph not final 13 sections
Antispetic HUMAN OTC DRUG LABEL 4 11344-567 MOUTHWASH 0.64 mg ORAL OTC monograph not final 13 sections
Antispetic HUMAN OTC DRUG LABEL 4 11673-072 MOUTHWASH 0.64 mg ORAL OTC monograph not final 12 sections
Antiseptic HUMAN OTC DRUG LABEL 4 11673-318 MOUTHWASH 0.64 mg ORAL OTC monograph not final 13 sections
Antiseptic HUMAN OTC DRUG LABEL 4 11673-318 MOUTHWASH 0.64 mg ORAL OTC monograph not final 13 sections
Tartar control plus HUMAN OTC DRUG LABEL 4 11673-434 MOUTHWASH 0.64 mg ORAL OTC monograph not final 12 sections
Tartar control plus HUMAN OTC DRUG LABEL 4 11673-434 MOUTHWASH 0.64 mg ORAL OTC monograph not final 12 sections
Antispetic HUMAN OTC DRUG LABEL 4 11673-664 MOUTHWASH 0.64 mg ORAL OTC monograph not final 12 sections
Antispetic HUMAN OTC DRUG LABEL 4 11673-664 MOUTHWASH 0.64 mg ORAL OTC monograph not final 12 sections
Antiseptic Mouth Rinse HUMAN OTC DRUG LABEL 4 11822-0072 MOUTHWASH 0.64 mg ORAL OTC monograph not final 13 sections
Tartar control plus HUMAN OTC DRUG LABEL 4 11822-0434 MOUTHWASH 0.64 mg ORAL OTC monograph not final 10 sections
Antispetic HUMAN OTC DRUG LABEL 4 11822-0664 MOUTHWASH 0.64 mg ORAL OTC monograph not final 13 sections
Antispetic HUMAN OTC DRUG LABEL 4 11822-0664 MOUTHWASH 0.64 mg ORAL OTC monograph not final 13 sections
Oral Care Antiseptic HUMAN OTC DRUG LABEL 4 11822-3108 MOUTHWASH 0.64 mg ORAL OTC monograph not final 12 sections
Oral Care Antiseptic HUMAN OTC DRUG LABEL 4 11822-3108 MOUTHWASH 0.64 mg ORAL OTC monograph not final 12 sections