epicriptine 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
ergot alkaloid derivatives 4148 88660-47-3

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • dihydro-beta-ergocryptin
  • dihydro-beta-ergocryptine
  • beta-dihydroergocryptine
  • Dihydro-.beta.-ergocryptine mesylate
  • epicriptine
  • Dihydro-.beta.-ergocryptine mesilate
a sec-butyl group replaces the isobutyl group of dihydroergocryptine
  • Molecular weight: 577.73
  • Formula: C32H43N5O5
  • CLOGP: 5.60
  • LIPINSKI: 2
  • HAC: 10
  • HDO: 3
  • TPSA: 118.21
  • ALOGS: -3.32
  • ROTB: 5

Drug dosage:

None

ADMET properties:

None

Approvals:

DateAgencyCompanyOrphan
None FDA

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

None

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

None

Drug Use | Suggest Off label Use Form| |View source of the data|

DiseaseRelationSNOMED_IDDOID
Senile dementia indication 15662003
Alzheimer's disease indication 26929004 DOID:10652




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

Dissociation levelDissociation constantType (acidic/basic)
pKa1 12.64 acidic
pKa2 13.28 acidic
pKa3 13.84 acidic
pKa4 7.56 Basic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

IDSource
65914-79-6 SECONDARY_CAS_RN
C3714499 UMLSCUI
CHEBI:135927 CHEBI
CHEMBL2106411 ChEMBL_ID
DB11275 DRUGBANK_ID
C527876 MESH_SUPPLEMENTAL_RECORD_UI
6220 INN_ID
5M64643B5U UNII
65667 PUBCHEM_CID
1426905 RXNORM
425819004 SNOMEDCT_US
75561002 SNOMEDCT_US

Pharmaceutical products:

ProductCategoryIngredientsNDCFormQuantityRouteMarketingLabel
Ergoloid Mesylates HUMAN PRESCRIPTION DRUG LABEL 4 53489-281 TABLET 0.11 mg ORAL ANDA 11 sections
Ergoloid Mesylates HUMAN PRESCRIPTION DRUG LABEL 4 68151-2780 TABLET 0.11 mg ORAL ANDA 10 sections