bucillamine 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |
| Stem definition | Drug id | CAS RN |
|---|---|---|
| 414 | 65002-17-7 |
Description:
| Molecule | Description |
|---|---|
|
Synonyms:
|
|
Drug dosage:
None
ADMET properties:
None
Approvals:
None
FDA Adverse Event Reporting System (Female)
| MedDRA adverse event term | Likelihood ratio | Likelihood ratio threshold | Patients taking drug having adverse event | Patients taking drug not having adverse event | Patients not taking drug having adverse event | Patients not taking drug not having adverse event |
|---|---|---|---|---|---|---|
| Lymphoproliferative disorder | 77.94 | 37.85 | 15 | 602 | 3175 | 63485230 |
| Interstitial lung disease | 69.27 | 37.85 | 25 | 592 | 61883 | 63426522 |
| Epstein-Barr virus associated lymphoproliferative disorder | 46.82 | 37.85 | 9 | 608 | 1885 | 63486520 |
| Diffuse large B-cell lymphoma | 45.57 | 37.85 | 11 | 606 | 6701 | 63481704 |
FDA Adverse Event Reporting System (Male)
None
FDA Adverse Event Reporting System (Geriatric)
| MedDRA adverse event term | Likelihood ratio | Likelihood ratio threshold | Patients taking drug having adverse event | Patients taking drug not having adverse event | Patients not taking drug having adverse event | Patients not taking drug not having adverse event |
|---|---|---|---|---|---|---|
| Lymphoproliferative disorder | 124.46 | 39.33 | 25 | 889 | 5590 | 79737884 |
| Interstitial lung disease | 89.16 | 39.33 | 37 | 877 | 112563 | 79630911 |
| Diffuse large B-cell lymphoma | 55.45 | 39.33 | 15 | 899 | 12134 | 79731340 |
| Epstein-Barr virus associated lymphoproliferative disorder | 50.76 | 39.33 | 11 | 903 | 3521 | 79739953 |
| Pneumocystis jirovecii pneumonia | 40.92 | 39.33 | 15 | 899 | 32493 | 79710981 |
FDA Adverse Event Reporting System (Pediatric)
None
Pharmacologic Action:
| Source | Code | Description |
|---|---|---|
| ATC | M01CC02 | MUSCULO-SKELETAL SYSTEM ANTIINFLAMMATORY AND ANTIRHEUMATIC PRODUCTS SPECIFIC ANTIRHEUMATIC AGENTS Penicillamine and similar agents |
| MeSH PA | D000700 | Analgesics |
| MeSH PA | D018712 | Analgesics, Non-Narcotic |
| MeSH PA | D000893 | Anti-Inflammatory Agents |
| MeSH PA | D000894 | Anti-Inflammatory Agents, Non-Steroidal |
| MeSH PA | D000975 | Antioxidants |
| MeSH PA | D018501 | Antirheumatic Agents |
| MeSH PA | D018373 | Peripheral Nervous System Agents |
| MeSH PA | D020011 | Protective Agents |
| MeSH PA | D018689 | Sensory System Agents |
Drug Use | Suggest Off label Use Form| |View source of the data|
None
🐶 Veterinary Drug Use
None
🐶 Veterinary products
None
Acid dissociation constants calculated using MoKa v3.0.0
| Dissociation level | Dissociation constant | Type (acidic/basic) |
|---|---|---|
| pKa1 | 3.2 | acidic |
| pKa2 | 8.46 | acidic |
| pKa3 | 9.51 | acidic |
| pKa4 | 13.13 | acidic |
Orange Book patent data (new drug applications)
None
Orange Book exclusivity data (new drug applications)
None
Bioactivity Summary:
None
External reference:
| ID | Source |
|---|---|
| D01809 | KEGG_DRUG |
| C0073917 | UMLSCUI |
| CHEBI:31312 | CHEBI |
| CHEMBL80830 | ChEMBL_ID |
| DB12160 | DRUGBANK_ID |
| 656604 | PUBCHEM_CID |
| C026535 | MESH_SUPPLEMENTAL_RECORD_UI |
| 5683 | INN_ID |
| R80LRA5WTF | UNII |
Pharmaceutical products:
None