sodium stibogluconate 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definition	Drug id	CAS RN
	4020	16037-91-5

Description:

Molecule	Description
Molfile Inchi Smiles Synonyms: pentostam sodium antimony gluconate sodium stibogluconate myostibin solusurmin stibatin stibogluconate sodium	Antimony complex where the metal may exist in either the pentavalent or trivalent states. The pentavalent gluconate is used in leishmaniasis. The trivalent gluconate is most frequently used in schistosomiasis. Molecular weight: 679.80 Formula: C12H20O17Sb2 CLOGP: -0.40 LIPINSKI: 3 HAC: 17 HDO: 8 TPSA: 276.27 ALOGS: -1.36 ROTB: 8

Molecule

Description

Molfile Inchi Smiles

Synonyms:

pentostam
sodium antimony gluconate
sodium stibogluconate
myostibin
solusurmin
stibatin
stibogluconate sodium

Antimony complex where the metal may exist in either the pentavalent or trivalent states. The pentavalent gluconate is used in leishmaniasis. The trivalent gluconate is most frequently used in schistosomiasis.

Molecular weight: 679.80
Formula: C12H20O17Sb2
CLOGP: -0.40
LIPINSKI: 3
HAC: 17
HDO: 8
TPSA: 276.27
ALOGS: -1.36
ROTB: 8

Drug dosage:

Dose	Unit	Route
0.85	g	P

ADMET properties:

None

Approvals:

None

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

None

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

Source	Code	Description
ATC	P01CB02	ANTIPARASITIC PRODUCTS, INSECTICIDES AND REPELLENTS ANTIPROTOZOALS AGENTS AGAINST LEISHMANIASIS AND TRYPANOSOMIASIS Antimony compounds
MeSH PA	D000871	Anthelmintics
MeSH PA	D000890	Anti-Infective Agents
MeSH PA	D000977	Antiparasitic Agents
MeSH PA	D000980	Antiplatyhelmintic Agents
MeSH PA	D000981	Antiprotozoal Agents
MeSH PA	D012556	Schistosomicides
CHEBI has role	CHEBI:35610	antineoplastic agents
CHEBI has role	CHEBI:70868	antileishmanial drugs

Drug Use | Suggest Off label Use Form| |View source of the data|

Disease	Relation	SNOMED_ID	DOID
Leishmaniasis	indication	80612004	DOID:9065

🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

None

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

ID	Source
D00582	KEGG_DRUG
C0030895	UMLSCUI
CHEBI:28148	CHEBI
CHEMBL2313755	ChEMBL_ID
CHEMBL2079699	ChEMBL_ID
CHEMBL3991035	ChEMBL_ID
CHEMBL2108095	ChEMBL_ID
DB05630	DRUGBANK_ID
16683012	PUBCHEM_CID
152209	RXNORM
004469	NDDF
324951006	SNOMEDCT_US
419379007	SNOMEDCT_US
D000967	MESH_DESCRIPTOR_UI

Pharmaceutical products:

None