benzamycin Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
antibiotics, produced by Streptomyces strains 3875 376597-09-0

Description:

MoleculeDescription

Synonyms:

  • benzamycin
  • Benzoyl peroxide-erythromyxin mixt.
  • Molecular weight: 976.17
  • Formula: C51H77NO17
  • CLOGP:
  • LIPINSKI: None
  • HAC: None
  • HDO: None
  • TPSA:
  • ALOGS:
  • ROTB: None

Drug dosage:

None

ADMET properties:

None

Approvals:

None

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

Pharmacologic Action:

None

Drug Use (View source of the data)

DiseaseRelationSNOMED_IDDOID
Acne vulgaris indication 88616000
Erythroderma contraindication 399992009
Inflammatory dermatosis contraindication 703938007

Acid dissociation constants calculated using MoKa v3.0.0

None

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

TargetClassPharosUniProtActionTypeActivity value
(-log[M])
Mechanism
action
Bioact sourceMoA source
Motilin receptor GPCR IC50 7.36 CHEMBL
Potassium voltage-gated channel subfamily H member 2 Ion channel IC50 7.41 CHEMBL

External reference:

IDSource
C0385222 UMLSCUI
CHEMBL532 ChEMBL_ID
CHEMBL1200370 ChEMBL_ID
C097386 MESH_SUPPLEMENTAL_RECORD_UI
12560 PUBCHEM_CID
117919 RXNORM
185 MMSL

Pharmaceutical products:

None