sodium gualenate 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definition	Drug id	CAS RN
	3874	6223-35-4

Description:

Molecule

Description

Molfile Inchi Smiles

Synonyms:

azulene sulfonate
sodium guaiazulenesulfonate
sodium gualenate
guaiazulenesulfonic acid sodium

Molecular weight: 278.37
Formula: C15H18O3S
CLOGP: 2.95
LIPINSKI: 0
HAC: 3
HDO: 1
TPSA: 54.37
ALOGS: -3.68
ROTB: 2

Drug dosage:

None

ADMET properties:

None

Approvals:

Date	Agency	Company	Orphan
Jan. 1, 1986	YEAR INTRODUCED

FDA Adverse Event Reporting System (Female)

MedDRA adverse event term	Likelihood ratio	Likelihood ratio threshold	Patients taking drug having adverse event	Patients taking drug not having adverse event	Patients not taking drug having adverse event	Patients not taking drug not having adverse event
Hepatic function abnormal	51.24	45.36	17	526	37125	63451354

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

MedDRA adverse event term	Likelihood ratio	Likelihood ratio threshold	Patients taking drug having adverse event	Patients taking drug not having adverse event	Patients not taking drug having adverse event	Patients not taking drug not having adverse event
Hepatic function abnormal	48.44	30.04	24	1335	73083	79669946
Platelet count decreased	44.15	30.04	32	1327	194632	79548397
Interstitial lung disease	36.21	30.04	23	1336	112577	79630452
Malignant neoplasm progression	32.26	30.04	23	1336	135967	79607062

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

None

Drug Use | Suggest Off label Use Form| |View source of the data|

None

🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

Dissociation level	Dissociation constant	Type (acidic/basic)
pKa1	2.25	acidic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

ID	Source
D02075	KEGG_DRUG
CHEBI:135153	CHEBI
CHEMBL1837010	ChEMBL_ID
C035058	MESH_SUPPLEMENTAL_RECORD_UI
1630	INN_ID
19WSH095WP	UNII
C0900866	UMLSCUI
23669592	PUBCHEM_CID

Pharmaceutical products:

None