parethoxycaine 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definition	Drug id	CAS RN
local anaesthetics	3805	94-23-5

Description:

Molecule

Description

Molfile Inchi Smiles

Synonyms:

parethoxycaine
parethoxycaine hydrochloride
parethoxycaine HCl

Molecular weight: 265.35
Formula: C15H23NO3
CLOGP: 3.96
LIPINSKI: 0
HAC: 4
HDO: 0
TPSA: 38.77
ALOGS: -2.37
ROTB: 9

Drug dosage:

None

ADMET properties:

None

Approvals:

None

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

None

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

None

Drug Use | Suggest Off label Use Form| |View source of the data|

None

🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

Dissociation level	Dissociation constant	Type (acidic/basic)
pKa1	8.8	Basic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

Target	Class	Pharos	UniProt	Action	Type	Activity value (-log[M])	Mechanism action	Bioact source	MoA source
Sodium channel alpha subunits; brain (Types I, II, III)	Ion channel	P35498 Q99250 Q9NY46	SCN1A_HUMAN SCN2A_HUMAN SCN3A_HUMAN		IC50	4.62		CHEMBL

External reference:

ID	Source
136-46-9	SECONDARY_CAS_RN
C0771503	UMLSCUI
CHEBI:135095	CHEBI
CHEMBL421669	ChEMBL_ID
7183	PUBCHEM_CID
18	INN_ID
68E52E5J67	UNII
236249	RXNORM
005504	NDDF
005505	NDDF
CHEMBL1603742	ChEMBL_ID

Pharmaceutical products:

None