meprylcaine 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definition	Drug id	CAS RN
local anaesthetics	3770	495-70-5

Description:

Molecule

Description

Molfile Inchi Smiles

Synonyms:

meprylcaine
epirocaine
oracaine
meprylcaine hydrochloride
meprylcaine HCl

Molecular weight: 235.33
Formula: C14H21NO2
CLOGP: 3.37
LIPINSKI: 0
HAC: 3
HDO: 1
TPSA: 38.33
ALOGS: -3.35
ROTB: 7

Drug dosage:

None

ADMET properties:

None

Approvals:

None

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

None

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

None

Drug Use | Suggest Off label Use Form| |View source of the data|

None

🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

Dissociation level	Dissociation constant	Type (acidic/basic)
pKa1	9.9	Basic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

Target	Class	Pharos	UniProt	Action	Type	Activity value (-log[M])	Mechanism action	Bioact source	MoA source
Sodium channel alpha subunits; brain (Types I, II, III)	Ion channel	P35498 Q99250 Q9NY46	SCN1A_HUMAN SCN2A_HUMAN SCN3A_HUMAN		IC50	5.12		CHEMBL

External reference:

ID	Source
D01417	KEGG_DRUG
956-03-6	SECONDARY_CAS_RN
C0301288	UMLSCUI
CHEBI:93147	CHEBI
CHEMBL127810	ChEMBL_ID
4065	PUBCHEM_CID
370	INN_ID
82YT7WU9PW	UNII
15009009	SNOMEDCT_US
CHEMBL2104800	ChEMBL_ID

Pharmaceutical products:

None