meprylcaine 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
local anaesthetics 3770 495-70-5

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • meprylcaine
  • epirocaine
  • oracaine
  • meprylcaine hydrochloride
  • meprylcaine HCl
  • Molecular weight: 235.33
  • Formula: C14H21NO2
  • CLOGP: 3.37
  • LIPINSKI: 0
  • HAC: 3
  • HDO: 1
  • TPSA: 38.33
  • ALOGS: -3.35
  • ROTB: 7

Drug dosage:

None

ADMET properties:

None

Approvals:

None

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

None

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

None

Drug Use | Suggest Off label Use Form| |View source of the data|

None




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

Dissociation levelDissociation constantType (acidic/basic)
pKa1 9.9 Basic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

TargetClassPharosUniProtActionTypeActivity value
(-log[M])
Mechanism
action
Bioact sourceMoA source
Sodium channel alpha subunits; brain (Types I, II, III) Ion channel IC50 5.12 CHEMBL

External reference:

IDSource
D01417 KEGG_DRUG
956-03-6 SECONDARY_CAS_RN
C0301288 UMLSCUI
CHEBI:93147 CHEBI
CHEMBL127810 ChEMBL_ID
4065 PUBCHEM_CID
370 INN_ID
82YT7WU9PW UNII
15009009 SNOMEDCT_US
CHEMBL2104800 ChEMBL_ID

Pharmaceutical products:

None